8G32
 
 | | Pro-form of a CDCL short from E. anophelis | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, GLYCEROL, ... | | 著者 | Johnstone, B.A, Christie, M.P, Morton, C.J, Parker, M.W. | | 登録日 | 2023-02-06 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Distant relatives of a eukaryotic cell-specific toxin family evolved a complement-like mechanism to kill bacteria.
Nat Commun, 15, 2024
|
|
6OGO
 | | Crystal structure of NDM-9 metallo-beta-lactamase | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Raczynska, J.E, Imiolczyk, B, Jaskolski, M. | | 登録日 | 2019-04-03 | | 公開日 | 2020-04-15 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Flexible loops of New Delhi metallo-beta-lactamase modulate its activity towards different substrates.
Int.J.Biol.Macromol., 158, 2020
|
|
8G71
 | | Spike/Nb2 complex with 1 RBD up | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Ye, G, Bu, F, Liu, B, Li, F. | | 登録日 | 2023-02-16 | | 公開日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (2.1 Å) | | 主引用文献 | SARS-CoV-2 spike/Nb2 complex with 1 RBD up
To Be Published
|
|
6OHW
 | | Structural basis for human coronavirus attachment to sialic acid receptors. Apo-HCoV-OC43 S | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike surface glycoprotein, ... | | 著者 | Tortorici, M.A, Walls, A.C, Lang, Y, Wang, C, Li, Z, Koerhuis, D, Boons, G.J, Bosch, B.J, Rey, F.A, de Groot, R, Veesler, D. | | 登録日 | 2019-04-07 | | 公開日 | 2019-06-05 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural basis for human coronavirus attachment to sialic acid receptors.
Nat.Struct.Mol.Biol., 26, 2019
|
|
5LDZ
 | | Quadruple space group ambiguity due to rotational and translational non-crystallographic symmetry in human liver fructose-1,6-bisphosphatase | | 分子名称: | CHLORIDE ION, Fructose-1,6-bisphosphatase 1, SULFATE ION, ... | | 著者 | Ruf, A, Tetaz, T, Schott, B, Joseph, C, Rudolph, M.G. | | 登録日 | 2016-06-29 | | 公開日 | 2016-10-26 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Quadruple space-group ambiguity owing to rotational and translational noncrystallographic symmetry in human liver fructose-1,6-bisphosphatase.
Acta Crystallogr D Struct Biol, 72, 2016
|
|
7RK7
 | | The complex between TIL 1383i TCR and human Class I MHC HLA-A2 with the bound Tyrosinase(369-377)(N371D) nonameric peptide | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A alpha chain, ... | | 著者 | Singh, N.K, Davancaze, L.M, Arbuiso, A, Weiss, L.I, Keller, G.L.J, Baker, B.M. | | 登録日 | 2021-07-22 | | 公開日 | 2022-11-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | | 主引用文献 | The complex between TIL 1383i TCR and human Class I MHC HLA-A2 with the bound Tyrosinase(369-377)(N371D) nonameric peptide
To Be Published
|
|
6ONA
 | |
6YUR
 | | Crystal structure of S. aureus FabI inhibited by SKTS1 | | 分子名称: | 6-[4-(4-hexyl-2-oxidanyl-phenoxy)phenoxy]pyridin-2-ol, Enoyl-[acyl-carrier-protein] reductase [NADPH], NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Weinrich, J.D, Eltschkner, S, Schiebel, J, Kehrein, J, Le, T.A, Davoodi, S, Merget, B, Tonge, P.J, Engels, B, Sotriffer, C.A, Kisker, C. | | 登録日 | 2020-04-27 | | 公開日 | 2021-03-24 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | A Long Residence Time Enoyl-Reductase Inhibitor Explores an Extended Binding Region with Isoenzyme-Dependent Tautomer Adaptation and Differential Substrate-Binding Loop Closure.
Acs Infect Dis., 7, 2021
|
|
8EAW
 | |
8GE0
 | |
7BII
 | | Crystal structure of Nematocida HUWE1 | | 分子名称: | E3 ubiquitin-protein ligase HUWE1 | | 著者 | Grabarczyk, D.B, Petrova, O.A, Meinhart, A, Kessler, D, Clausen, T. | | 登録日 | 2021-01-12 | | 公開日 | 2021-07-28 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.037 Å) | | 主引用文献 | HUWE1 employs a giant substrate-binding ring to feed and regulate its HECT E3 domain.
Nat.Chem.Biol., 17, 2021
|
|
8JTR
 | | Cryo-EM structure of GeoCas9-sgRNA binary complex | | 分子名称: | CRISPR-associated endonuclease Cas9, sgRNA (139-bp) | | 著者 | Shen, P.P, Liu, B.B, Li, X, Zhang, L.L, Chen, C.-C, Guo, R.-T. | | 登録日 | 2023-06-22 | | 公開日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | | 主引用文献 | Cryo-EM structure of GeoCas9-sgRNA binary complex
To Be Published
|
|
7BAG
 | | C3b in complex with CP40 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETAMIDE, AMINO GROUP, ... | | 著者 | Lamers, C, Xue, X, Smiesko, M, van Son, H, Wagner, B, Sfyroera, G, Gros, P, Lambris, J, Ricklin, D. | | 登録日 | 2020-12-15 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Insight into mode-of-action and structural determinants of the compstatin family of clinical complement inhibitors.
Nat Commun, 13, 2022
|
|
6VPL
 | |
7MNX
 | | Crystal Structure of Nup358/RanBP2 Ran-binding domain 2 in complex with Ran-GPPNHP | | 分子名称: | E3 SUMO-protein ligase RanBP2, GTP-binding nuclear protein Ran, MAGNESIUM ION, ... | | 著者 | Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A. | | 登録日 | 2021-05-01 | | 公開日 | 2022-06-15 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022
|
|
5LIH
 | | Structure of a peptide-substrate bound to PKCiota core kinase domain | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MANGANESE (II) ION, ... | | 著者 | Soriano, E.V, Purkiss, A.G, McDonald, N.Q. | | 登録日 | 2016-07-14 | | 公開日 | 2016-09-14 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | aPKC Inhibition by Par3 CR3 Flanking Regions Controls Substrate Access and Underpins Apical-Junctional Polarization.
Dev.Cell, 38, 2016
|
|
5LVX
 | | Crystal structure of glucocerebrosidase with an inhibitory quinazoline modulator | | 分子名称: | 11-[(2~{R})-2-[(2-pyridin-3-ylquinazolin-4-yl)amino]-2,3-dihydro-1~{H}-inden-5-yl]undec-10-ynoic acid, 11-[(2~{S})-2-[(2-pyridin-3-ylquinazolin-4-yl)amino]-2,3-dihydro-1~{H}-inden-5-yl]undec-10-ynoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zheng, J, Chen, L, Skinner, O.S, Lansbury, P, Skerlj, R, Mrosek, M, Heunisch, U, Krapp, S, Weigand, S, Charrow, J, Schwake, M, Kelleher, N.L, Silverman, R.B, Krainc, D. | | 登録日 | 2016-09-14 | | 公開日 | 2017-10-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | beta-Glucocerebrosidase Modulators Promote Dimerization of beta-Glucocerebrosidase and Reveal an Allosteric Binding Site.
J. Am. Chem. Soc., 140, 2018
|
|
6UDJ
 | | HIV-1 bNAb 1-18 in complex with BG505 SOSIP.664 and 10-1074 | | 分子名称: | 1-18 Fab Heavy Chain, 1-18 Fab Light Chain, 10-1074 Fab Heavy Chain, ... | | 著者 | Abernathy, M.E, Barnes, C.O, Gristick, H.B, Bjorkman, P.J. | | 登録日 | 2019-09-19 | | 公開日 | 2020-01-29 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody.
Cell, 180, 2020
|
|
6UDK
 | | HIV-1 bNAb 1-55 in complex with modified BG505 SOSIP-based immunogen RC1 and 10-1074 | | 分子名称: | 1-55 Fab Heavy Chain, 1-55 Fab Light Chain, 10-1074 Fab Heavy Chain, ... | | 著者 | Abernathy, M.E, Barnes, C.O, Gristick, H.B, Bjorkman, P.J. | | 登録日 | 2019-09-19 | | 公開日 | 2020-01-29 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody.
Cell, 180, 2020
|
|
9BAF
 | | Solution NMR structure of conofurin-Delta | | 分子名称: | Alpha-conotoxin LvIA | | 著者 | Harvey, P.J, Craik, D.J, Hone, A.J, McIntosh, J.M. | | 登録日 | 2024-04-04 | | 公開日 | 2024-07-03 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Design, Synthesis, and Structure-Activity Relationships of Novel Peptide Derivatives of the Severe Acute Respiratory Syndrome-Coronavirus-2 Spike-Protein that Potently Inhibit Nicotinic Acetylcholine Receptors.
J.Med.Chem., 67, 2024
|
|
5ZWO
 | | Cryo-EM structure of the yeast B complex at average resolution of 3.9 angstrom | | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 23 kDa U4/U6.U5 small nuclear ribonucleoprotein component, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, ... | | 著者 | Bai, R, Wan, R, Yan, C, Shi, Y. | | 登録日 | 2018-05-16 | | 公開日 | 2018-08-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
Science, 360, 2018
|
|
7PR5
 | | Cocrystal of an RSL-N23H and sulfonato-thiacalix[4]arene - zinc complex | | 分子名称: | Fucose-binding lectin protein, GLYCEROL, ZINC ION, ... | | 著者 | Flood, R.J, Ramberg, K, Guagnini, F, Crowley, P.B. | | 登録日 | 2021-09-20 | | 公開日 | 2022-03-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Protein Frameworks with Thiacalixarene and Zinc.
Cryst.Growth Des., 22, 2022
|
|
7NG3
 | | Crystal structure of MG-132 covalently bound to the main protease (3CLpro/Mpro) of SARS-CoV-2 in spacegroup P1. | | 分子名称: | 3C-like proteinase, CHLORIDE ION, N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S)-1-hydroxy-4-methylpentan-2-yl]-L-leucinamide | | 著者 | Costanzi, E, Demitri, N, Giabbai, B, Storici, P. | | 登録日 | 2021-02-08 | | 公開日 | 2021-04-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural and Biochemical Analysis of the Dual Inhibition of MG-132 against SARS-CoV-2 Main Protease (Mpro/3CLpro) and Human Cathepsin-L.
Int J Mol Sci, 22, 2021
|
|
8EPE
 | | Engineering Crystals with Tunable Symmetries from 14- or 16-Base-Long DNA Strands | | 分子名称: | DNA (5'-D(*CP*GP*AP*CP*G)-3'), DNA (5'-D(P*CP*CP*CP*GP*C)-3'), DNA (5'-D(P*CP*GP*TP*GP*GP*G)-3') | | 著者 | Zhang, C, Zhao, J, Lu, B, Sha, R, Seeman, N.C, Noinaj, N, Mao, C. | | 登録日 | 2022-10-05 | | 公開日 | 2023-03-08 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Engineering DNA Crystals toward Studying DNA-Guest Molecule Interactions.
J.Am.Chem.Soc., 145, 2023
|
|
6OLY
 | |
