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1HVU
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HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE COMPLEXED WITH A 33-BASE NUCLEOTIDE RNA PSEUDOKNOT
分子名称: PROTEIN (HIV-1 REVERSE TRANSCRIPTASE), RNA (33 NUCLEOTIDE RNA PSEUDOKNOT)
著者Jaeger, J, Restle, T, Steitz, T.A.
登録日1998-06-30
公開日1999-01-13
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (4.75 Å)
主引用文献The structure of HIV-1 reverse transcriptase complexed with an RNA pseudoknot inhibitor.
EMBO J., 17, 1998
1HVV
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SELF-ASSOCIATION OF THE H3 REGION OF SYNTAXIN 1A: IMPLICATIONS FOR SNARE COMPLEX ASSEMBLY
分子名称: D(-)-TARTARIC ACID, SYNTAXIN 1A
著者Misura, K.M.S, Scheller, R.H, Weis, W.I.
登録日2001-01-08
公開日2001-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Self-association of the H3 region of syntaxin 1A. Implications for intermediates in SNARE complex assembly.
J.Biol.Chem., 276, 2001
1HVW
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HAIRPINLESS MUTANT OF OMEGA-ATRACOTOXIN-HV1A
分子名称: OMEGA-ATRACOTOXIN-HV1A
著者Fletcher, J.I, King, G.F.
登録日2001-01-08
公開日2001-01-17
最終更新日2024-11-06
実験手法SOLUTION NMR
主引用文献Functional significance of the beta hairpin in the insecticidal neurotoxin omega-atracotoxin-Hv1a.
J.Biol.Chem., 276, 2001
1HVX
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BACILLUS STEAROTHERMOPHILUS ALPHA-AMYLASE
分子名称: ALPHA-AMYLASE, CALCIUM ION, SODIUM ION
著者Suvd, D, Fujimoto, Z, Takase, K, Matsumura, M, Mizuno, H.
登録日2001-01-08
公開日2001-01-31
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of Bacillus stearothermophilus alpha-amylase: possible factors determining the thermostability.
J.Biochem., 129, 2001
1HVY
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Human thymidylate synthase complexed with dUMP and Raltitrexed, an antifolate drug, is in the closed conformation
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, BETA-MERCAPTOETHANOL, THYMIDYLATE SYNTHASE, ...
著者Phan, J, Koli, S, Minor, W, Dunlap, R.B, Berger, S.H, Lebioda, L.
登録日2001-01-08
公開日2001-01-31
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Human thymidylate synthase is in the closed conformation when complexed with dUMP and raltitrexed, an antifolate drug
Biochemistry, 40, 2001
1HVZ
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RTD-1, A CYCLIC ANTIMICROBIAL DEFENSIN FROM RHESUS MACAQUE LEUKOCYTES
分子名称: THETA DEFENSIN 1
著者Craik, D.J, Trabi, M, Schirra, H.J.
登録日2001-01-09
公開日2001-05-30
最終更新日2024-10-09
実験手法SOLUTION NMR
主引用文献Three-dimensional structure of RTD-1, a cyclic antimicrobial defensin from Rhesus macaque leukocytes.
Biochemistry, 40, 2001
1HW1
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THE FADR-DNA COMPLEX: TRANSCRIPTIONAL CONTROL OF FATTY ACID METABOLISM IN ESCHERICHIA COLI
分子名称: FATTY ACID METABOLISM REGULATOR PROTEIN, SULFATE ION, ZINC ION
著者Xu, Y, Heath, R.J, Li, Z, Rock, C.O, White, S.W.
登録日2001-01-09
公開日2001-01-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The FadR.DNA complex. Transcriptional control of fatty acid metabolism in Escherichia coli.
J.Biol.Chem., 276, 2001
1HW2
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FADR-DNA COMPLEX: TRANSCRIPTIONAL CONTROL OF FATTY ACID METABOLISM IN ECHERICHIA COLI
分子名称: 5'-D(*CP*GP*AP*TP*CP*TP*GP*GP*TP*CP*CP*GP*AP*CP*CP*AP*GP*AP*TP*GP*CP*T)-3', 5'-D(*G*CP*AP*TP*CP*TP*GP*GP*TP*CP*GP*GP*AP*CP*CP*AP*GP*AP*TP*CP*GP*A)-3', FATTY ACID METABOLISM REGULATOR PROTEIN, ...
著者Xu, Y, Heath, R.J, Li, Z, Rock, C.O, White, S.W.
登録日2001-01-09
公開日2001-01-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献The FadR.DNA complex. Transcriptional control of fatty acid metabolism in Escherichia coli.
J.Biol.Chem., 276, 2001
1HW3
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STRUCTURE OF HUMAN THYMIDYLATE SYNTHASE SUGGESTS ADVANTAGES OF CHEMOTHERAPY WITH NONCOMPETITIVE INHIBITORS
分子名称: 1,2-ETHANEDIOL, SULFATE ION, THYMIDYLATE SYNTHASE
著者Phan, J, Steadman, J.D, Koli, S, Ding, W.C, Minor, W, Dunlap, R.B, Berger, S.H, Lebioda, L.
登録日2001-01-09
公開日2001-01-24
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of human thymidylate synthase suggests advantages of chemotherapy with noncompetitive inhibitors.
J.Biol.Chem., 276, 2001
1HW4
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STRUCTURE OF THYMIDYLATE SYNTHASE SUGGESTS ADVANTAGES OF CHEMOTHERAPY WITH NONCOMPETITIVE INHIBITORS
分子名称: 1,2-ETHANEDIOL, SULFATE ION, THYMIDYLATE SYNTHASE
著者Phan, J, Steadman, J.D, Koli, S, Ding, W.C, Minor, W, Dunlap, R.B, Berger, S.H, Lebioda, L.
登録日2001-01-09
公開日2001-01-24
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Structure of human thymidylate synthase suggests advantages of chemotherapy with noncompetitive inhibitors.
J.Biol.Chem., 276, 2001
1HW5
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THE CAP/CRP VARIANT T127L/S128A
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CATABOLITE GENE ACTIVATOR
著者Chu, S.Y, Tordova, M, Gilliland, G.L, Gorshkova, I, Shi, Y.
登録日2001-01-09
公開日2001-01-17
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献The structure of the T127L/S128A mutant of cAMP receptor protein facilitates promoter site binding
J.Biol.Chem., 276, 2001
1HW6
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CRYSTAL STRUCTURE OF APO-2,5-DIKETO-D-GLUCONATE REDUCTASE
分子名称: 2,5-DIKETO-D-GLUCONIC ACID REDUCTASE, CHLORIDE ION, MAGNESIUM ION
著者Sanli, G, Blaber, M.
登録日2001-01-09
公開日2001-06-20
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural assembly of the active site in an aldo-keto reductase by NADPH cofactor.
J.Mol.Biol., 309, 2001
1HW7
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HSP33, HEAT SHOCK PROTEIN WITH REDOX-REGULATED CHAPERONE ACTIVITY
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, HEAT SHOCK PROTEIN HSP33, SULFATE ION, ...
著者Vijayalakshmi, J, Mukhergee, M.K, Graumann, J, Jakob, U, Saper, M.A.
登録日2001-01-09
公開日2001-05-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The 2.2 A crystal structure of Hsp33: a heat shock protein with redox-regulated chaperone activity.
Structure, 9, 2001
1HW8
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COMPLEX OF THE CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH COMPACTIN (ALSO KNOWN AS MEVASTATIN)
分子名称: (3R,5R)-3,5-dihydroxy-7-[(1S,2S,8S,8aR)-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]h eptanoic acid, ADENOSINE-5'-DIPHOSPHATE, HMG-COA REDUCTASE
著者Istvan, E.S, Deisenhofer, J.
登録日2001-01-09
公開日2001-05-11
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural mechanism for statin inhibition of HMG-CoA reductase.
Science, 292, 2001
1HW9
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COMPLEX OF THE CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH SIMVASTATIN
分子名称: ADENOSINE-5'-DIPHOSPHATE, HMG-COA REDUCTASE, Simvastatin acid
著者Istvan, E.S, Deisenhofer, J.
登録日2001-01-09
公開日2001-05-11
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Structural mechanism for statin inhibition of HMG-CoA reductase.
Science, 292, 2001
1HWG
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1:2 COMPLEX OF HUMAN GROWTH HORMONE WITH ITS SOLUBLE BINDING PROTEIN
分子名称: GROWTH HORMONE, GROWTH HORMONE BINDING PROTEIN
著者Sundstrom, S.M, Lundqvist, T.
登録日1996-11-13
公開日1997-11-19
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of an antagonist mutant of human growth hormone, G120R, in complex with its receptor at 2.9 A resolution.
J.Biol.Chem., 271, 1996
1HWH
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1:1 COMPLEX OF HUMAN GROWTH HORMONE MUTANT G120R WITH ITS SOLUBLE BINDING PROTEIN
分子名称: GROWTH HORMONE, GROWTH HORMONE BINDING PROTEIN
著者Sundstrom, S.M, Lundqvist, T.
登録日1996-11-13
公開日1997-11-19
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of an antagonist mutant of human growth hormone, G120R, in complex with its receptor at 2.9 A resolution.
J.Biol.Chem., 271, 1996
1HWI
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COMPLEX OF THE CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH FLUVASTATIN
分子名称: (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid, ADENOSINE-5'-DIPHOSPHATE, HMG-COA REDUCTASE
著者Istvan, E.S, Deisenhofer, J.
登録日2001-01-09
公開日2001-05-11
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural mechanism for statin inhibition of HMG-CoA reductase.
Science, 292, 2001
1HWJ
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COMPLEX OF THE CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH CERIVASTATIN
分子名称: 7-[4-(4-FLUORO-PHENYL)-5-HYDROXYMETHYL-2,6-DIISOPROPYL-PYRIDIN-3-YL]-3,5-DIHYDROXY-HEPTANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, HMG-COA REDUCTASE
著者Istvan, E.S, Deisenhofer, J.
登録日2001-01-09
公開日2001-05-11
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structural mechanism for statin inhibition of HMG-CoA reductase.
Science, 292, 2001
1HWK
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COMPLEX OF THE CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH ATORVASTATIN
分子名称: 7-[2-(4-FLUORO-PHENYL)-5-ISOPROPYL-3-PHENYL-4-PHENYLCARBAMOYL-PYRROL-1-YL]- 3,5-DIHYDROXY-HEPTANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, HMG-COA REDUCTASE
著者Istvan, E.S, Deisenhofer, J.
登録日2001-01-09
公開日2001-05-11
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Structural mechanism for statin inhibition of HMG-CoA reductase.
Science, 292, 2001
1HWL
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COMPLEX OF THE CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH ROSUVASTATIN (FORMALLY KNOWN AS ZD4522)
分子名称: 7-[4-(4-FLUORO-PHENYL)-6-ISOPROPYL-2-(METHANESULFONYL-METHYL-AMINO)-PYRIMIDIN-5-YL] -3,5-DIHYDROXY-HEPTANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, HMG-COA REDUCTASE
著者Istvan, E.S, Deisenhofer, J.
登録日2001-01-09
公開日2001-05-11
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural mechanism for statin inhibition of HMG-CoA reductase.
Science, 292, 2001
1HWM
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EBULIN,ORTHORHOMBIC CRYSTAL FORM MODEL
分子名称: EBULIN, alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose
著者Pascal, J.M, Day, P.J, Monzingo, A.F, Ernst, S.R, Robertus, J.D.
登録日2001-01-09
公開日2001-01-24
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献2.8-A crystal structure of a nontoxic type-II ribosome-inactivating protein, ebulin l.
Proteins, 43, 2001
1HWN
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EBULIN COMPLEXED WITH GALACTOSE, TRIGONAL CRYSTAL FORM
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EBULIN, beta-D-galactopyranose
著者Pascal, J.M, Day, P.J, Monzingo, A.F, Ernst, S.R, Robertus, J.D.
登録日2001-01-09
公開日2001-01-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献2.8-A crystal structure of a nontoxic type-II ribosome-inactivating protein, ebulin l.
Proteins, 43, 2001
1HWO
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EBULIN COMPLEXED WITH LACTOSE, TRIGONAL CRYSTAL FORM
分子名称: EBULIN, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Pascal, J.M, Day, P.J, Monzingo, A.F, Ernst, S.R, Robertus, J.D.
登録日2001-01-09
公開日2001-01-24
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献2.8-A crystal structure of a nontoxic type-II ribosome-inactivating protein, ebulin l.
Proteins, 43, 2001
1HWP
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EBULIN COMPLEXED WITH PTEROIC ACID, TRIGONAL CRYSTAL FORM
分子名称: EBULIN, PTEROIC ACID, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ...
著者Pascal, J.M, Day, P.J, Monzingo, A.F, Ernst, S.R, Robertus, J.D.
登録日2001-01-09
公開日2001-01-24
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献2.8-A crystal structure of a nontoxic type-II ribosome-inactivating protein, ebulin l.
Proteins, 43, 2001

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