PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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3QB7	Interleukin-4 mutant RGA bound to cytokine receptor common gamma 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit gamma, ... 著者 Bates, D.L, Junttila, I.S, Creusot, R.J, Moraga, I, Lupardus, P, Fathman, C.G, Paul, W.E, Garcia, K.C. 登録日 2011-01-12 公開日 2012-04-25 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.245 Å) 主引用文献 Redirecting cell-type specific cytokine responses with engineered interleukin-4 superkines. Nat.Chem.Biol., 8, 2012
3QFX	Trypanosoma brucei dihydrofolate reductase pyrimethamine complex 分子名称: 5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE, Bifunctional dihydrofolate reductase-thymidylate synthase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Vanichtanankul, J, Yuvaniyama, J, Taweechai, S, Chitnumsub, P, Kamchonwongpaisan, S, Yuthavong, Y. 登録日 2011-01-24 公開日 2011-06-29 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Trypanosomal dihydrofolate reductase reveals natural antifolate resistance Acs Chem.Biol., 6, 2011
3QJ7	Crystal Structure of the Mycobacterium tuberculosis Thymidylate synthase (ThyA) bound to dUMP 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, SPERMINE, Thymidylate synthase 著者 Reddy, M.C.M, Bruning, J.B, Harshbarger, W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) 登録日 2011-01-28 公開日 2011-06-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.504 Å) 主引用文献 Crystal structure of binary and ternary complexes of thymidylate synthase (ThyA) from Mycobacterium tuberculosis: insights into the selectivity and mode of inhibition To be Published
3QKA	Crystal structure of enoyl-CoA hydratase EchA5 from Mycobacterium marinum 分子名称: Enoyl-CoA hydratase, EchA5 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-01-31 公開日 2011-02-09 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3QLX	Candida glabrata dihydrofolate reductase complexed with NADPH and 6-methyl-5-[(3R)-3-(3,4,5-trimethoxyphenyl)pent-1-yn-1-yl]pyrimidine-2,4-diamine (UCP112A) 分子名称: 6-methyl-5-[(3R)-3-(3,4,5-trimethoxyphenyl)pent-1-yn-1-yl]pyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Paulsen, J.L, Bendel, S.D, Anderson, A.C. 登録日 2011-02-03 公開日 2011-07-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.239 Å) 主引用文献 Crystal Structures of Candida albicans Dihydrofolate Reductase Bound to Propargyl-Linked Antifolates Reveal the Flexibility of Active Site Loop Residues Critical for Ligand Potency and Selectivity. Chem.Biol.Drug Des., 78, 2011
3QME	Crystal Structure of an Anopheles gambiae Odorant-binding Protein AgamOBP22a with Bound Odorant Cyclohexanone 分子名称: AMMONIUM ION, CYCLOHEXANONE, Odorant binding protein (AGAP010409-PA) 著者 Ren, H, Zhang, S. 登録日 2011-02-04 公開日 2011-02-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.002 Å) 主引用文献 Crystal Structures of an Anopheles gambiae Odorant-binding Protein AgamOBP22a and Complexes with Bound Odorants To be Published
3QIY	Crystal Structure of BoNT/A LC complexed with Hydroxamate-based Inhibitor PT-1 分子名称: 1,2-ETHANEDIOL, 4-[bis(4-chlorobenzyl)amino]-N-hydroxybutanamide, Botulinum neurotoxin type A, ... 著者 Thompson, A.A, Han, G.W, Stevens, R.C. 登録日 2011-01-28 公開日 2011-04-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Characterization of Three Novel Hydroxamate-Based Zinc Chelating Inhibitors of the Clostridium botulinum Serotype A Neurotoxin Light Chain Metalloprotease Reveals a Compact Binding Site Resulting from 60/70 Loop Flexibility. Biochemistry, 50, 2011
3QMM	Structure of 6B, a thermostable mutant of Bacillus subtilis lipase obtained through directed evolution 分子名称: Lipase estA 著者 Sankaranarayanan, R, Kamal, M.Z. 登録日 2011-02-04 公開日 2011-10-05 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 In vitro evolved non-aggregating and thermostable lipase: structural and thermodynamic investigation J.Mol.Biol., 413, 2011
3QNX	Orthorhombic form of human IgA1 Fab fragment, sharing same Fv as IgG 分子名称: Fab fragment of IMMUNOGLOBULIN A1 HEAVY CHAIN, Fab fragment of IMMUNOGLOBULIN A1 LIGHT CHAIN, GLYCEROL 著者 Trajtenberg, F, Correa, A, Buschiazzo, A. 登録日 2011-02-09 公開日 2012-02-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of a human IgA1 Fab fragment at 1.55 angstrom resolution: potential effect of the constant domains on antigen-affinity modulation Acta Crystallogr.,Sect.D, 69, 2013
3QK5	Crystal structure of fatty acid amide hydrolase with small molecule inhibitor 分子名称: (3-{(3R)-1-[4-(1-benzothiophen-2-yl)pyrimidin-2-yl]piperidin-3-yl}-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)acetonitrile, 1,2-ETHANEDIOL, Fatty-acid amide hydrolase 1, ... 著者 Min, X, Walker, N.P.C, Wang, Z. 登録日 2011-01-31 公開日 2011-04-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Identification of potent, noncovalent fatty acid amide hydrolase (FAAH) inhibitors. Bioorg.Med.Chem.Lett., 21, 2011
3QQ7	Crystal Structure of the p97 N-terminal domain 分子名称: CHLORIDE ION, COBALT (II) ION, GLYCEROL, ... 著者 Haenzelmann, P, Schindelin, H. 登録日 2011-02-15 公開日 2011-06-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Hierarchical Binding of Cofactors to the AAA ATPase p97. Structure, 19, 2011
3QII	Crystal structure of tudor domain 2 of human PHD finger protein 20 分子名称: PHD finger protein 20, UNKNOWN ATOM OR ION 著者 Li, Z, Tempel, W, Wernimont, A.K, Chao, X, Bian, C, Lam, R, Crombet, L, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) 登録日 2011-01-27 公開日 2011-02-09 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structures of the Tudor domains of human PHF20 reveal novel structural variations on the Royal Family of proteins. Febs Lett., 586, 2012
3QQM	Crystal structure of a Putative amino-acid aminotransferase (NP_104211.1) from Mesorhizobium loti at 2.30 A resolution 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2011-02-15 公開日 2011-03-02 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of a Putative amino-acid aminotransferase (NP_104211.1) from Mesorhizobium loti at 2.30 A resolution To be published
3QTI	c-Met Kinase in Complex with NVP-BVU972 分子名称: 6-{[6-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-b]pyridazin-3-yl]methyl}quinoline, CHLORIDE ION, GLYCEROL, ... 著者 Appleton, B.A. 登録日 2011-02-22 公開日 2011-07-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A Drug Resistance Screen Using a Selective MET Inhibitor Reveals a Spectrum of Mutations That Partially Overlap with Activating Mutations Found in Cancer Patients. Cancer Res., 71, 2011
3QLS	Candida albicans dihydrofolate reductase complexed with NADPH and 6-methyl-5-[3-methyl-3-(3,4,5-trimethoxyphenyl)but-1-yn-1-yl]pyrimidine-2,4-diamine (UCP115A) 分子名称: 6-methyl-5-[3-methyl-3-(3,4,5-trimethoxyphenyl)but-1-yn-1-yl]pyrimidine-2,4-diamine, GLYCEROL, GLYCINE, ... 著者 Paulsen, J.L, Bendel, S.D, Anderson, A.C. 登録日 2011-02-03 公開日 2011-07-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.733 Å) 主引用文献 Crystal Structures of Candida albicans Dihydrofolate Reductase Bound to Propargyl-Linked Antifolates Reveal the Flexibility of Active Site Loop Residues Critical for Ligand Potency and Selectivity. Chem.Biol.Drug Des., 78, 2011
3QC0	Crystal structure of a sugar isomerase (SMc04130) from SINORHIZOBIUM MELILOTI 1021 at 1.45 A resolution 分子名称: TETRAETHYLENE GLYCOL, UNKNOWN LIGAND, ZINC ION, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2011-01-14 公開日 2011-04-06 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystal structure of a sugar isomerase (SMc04130) from SINORHIZOBIUM MELILOTI 1021 at 1.45 A resolution To be published
3QTL	Structural Basis for Dual-inhibition Mechanism of a Non-classical Kazal-type Serine Protease Inhibitor from Horseshoe Crab in Complex with Subtilisin 分子名称: Kazal-type serine protease inhibitor SPI-1, Subtilisin-like serin protease 著者 Shenoy, R.T, Sivaraman, J. 登録日 2011-02-23 公開日 2011-06-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for dual-inhibition mechanism of a non-classical kazal-type serine protease inhibitor from horseshoe crab in complex with subtilisin. Plos One, 6, 2011
3QUE	Human p38 MAP Kinase in Complex with Skepinone-L 分子名称: 2-[(2,4-difluorophenyl)amino]-7-{[(2R)-2,3-dihydroxypropyl]oxy}-10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-one, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside 著者 Gruetter, C, Mayer-Wrangowski, S, Richters, A, Rauh, D. 登録日 2011-02-23 公開日 2012-01-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor. Nat.Chem.Biol., 8, 2012
3QL1	Crystal Structure of Ribonuclease A Variant A4C/D83E/V118C 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Ribonuclease pancreatic, ... 著者 Arnold, U, Schoepfel, M. 登録日 2011-02-02 公開日 2012-02-29 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.29 Å) 主引用文献 Significant stabilization of ribonuclease A by additive effects Febs J., 279, 2012
3QLJ	Crystal structure of a short chain dehydrogenase from Mycobacterium avium 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, SODIUM ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-02-02 公開日 2011-02-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
5EBH	Crystal Structure HEW Lysozyme processed with the CrystalDirect automated mounting and cryo-cooling technology 分子名称: Lysozyme C 著者 Zander, U, Hoffmann, G, Cornaciu, I, Marquez, J.A. 登録日 2015-10-19 公開日 2016-04-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Automated harvesting and processing of protein crystals through laser photoablation. Acta Crystallogr D Struct Biol, 72, 2016
3QXI	Crystal structure of enoyl-CoA hydratase EchA1 from Mycobacterium marinum 分子名称: Enoyl-CoA hydratase EchA1 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-03-01 公開日 2011-03-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3Q6P	Salivary protein from Lutzomyia longipalpis. Selenomethionine derivative 分子名称: 43.2 kDa salivary protein, CITRIC ACID 著者 Andersen, J.F, Xu, X, Chang, B.W, Collin, N, Valenzuela, J.G, Ribeiro, J.M. 登録日 2011-01-03 公開日 2011-07-27 最終更新日 2019-10-23 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structure and function of a "yellow" protein from saliva of the sand fly Lutzomyia longipalpis that confers protective immunity against Leishmania major infection. J.Biol.Chem., 286, 2011
3Q80	Structure of Mtb 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (IspD) Complexed with CDP-ME 分子名称: 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase, 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL, CHLORIDE ION, ... 著者 Reddy, M.C.M, Bruning, J.B, Thurman, C, Ioerger, T.R, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) 登録日 2011-01-05 公開日 2011-05-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of Mycobacterium tuberculosis 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (IspD): a candidate antitubercular drug target Proteins, 2011
3Q8M	Crystal Structure of Human Flap Endonuclease FEN1 (D181A) in complex with substrate 5'-flap DNA and K+ 分子名称: DNA (5'-D(*AP*CP*CP*GP*TP*CP*C)-3'), DNA (5'-D(*AP*CP*TP*CP*TP*GP*CP*CP*TP*CP*AP*AP*GP*AP*CP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*GP*AP*GP*GP*CP*AP*GP*AP*GP*T)-3'), ... 著者 Tsutakawa, S.E, Classen, S, Chapados, B.R, Arvai, A, Finger, D.L, Guenther, G, Tomlinson, C.G, Thompson, P, Sarker, A.H, Shen, B, Cooper, P.K, Grasby, J.A, Tainer, J.A. 登録日 2011-01-06 公開日 2011-04-27 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Human Flap Endonuclease Structures, DNA Double-Base Flipping, and a Unified Understanding of the FEN1 Superfamily. Cell(Cambridge,Mass.), 145, 2011

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