PDB: 231319 件ウェブページステータス検索Chemie searchBIRD

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5UIJ	X-ray structure of The FdtF N-formyltransferase from Salmonella enteric O60 in complex with TDP 分子名称: 1,2-ETHANEDIOL, Formyltransferase, SODIUM ION, ... 著者 Thoden, J.B, Woodford, C.R, Holden, H.M. 登録日 2017-01-14 公開日 2017-03-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular architecture of an N-formyltransferase from Salmonella enterica O60. J. Struct. Biol., 200, 2017
4FIT	FHIT-APO 分子名称: FRAGILE HISTIDINE TRIAD PROTEIN 著者 Lima, C.D, Klein, M.G, Hendrickson, W.A. 登録日 1997-09-25 公開日 1998-03-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure-based analysis of catalysis and substrate definition in the HIT protein family. Science, 278, 1997
2W37	CRYSTAL STRUCTURE OF THE HEXAMERIC CATABOLIC ORNITHINE TRANSCARBAMYLASE FROM Lactobacillus hilgardii 分子名称: NICKEL (II) ION, ORNITHINE CARBAMOYLTRANSFERASE, CATABOLIC 著者 de las Rivas, B, Fox, G.C, Angulo, I, Rodriguez, H, Munoz, R, Mancheno, J.M. 登録日 2008-11-06 公開日 2009-11-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of the Hexameric Catabolic Ornithine Transcarbamylase from Lactobacillus Hilgardii: Structural Insights Into the Oligomeric Assembly and Metal Binding. J.Mol.Biol., 393, 2009
7MZ2	Structure of human DNA polymerase beta complexed with dzA at N-1 of the template base paired with incoming dTTP 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*CP*GP*AP*CP*GP*(4DU)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*T)-3'), ... 著者 Koag, M.-C, Lee, S. 登録日 2021-05-23 公開日 2022-05-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.088 Å) 主引用文献 Structure of human DNA polymerase beta complexed with dzA at N-1 of the template base paired with incoming dTTP To Be Published
7MZ1	Structure of human DNA polymerase beta complexed with dzA in the template base paired with incoming non-hydrolyzable TTP 分子名称: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*CP*CP*GP*AP*CP*(4DU)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... 著者 Koag, M.-C, Lee, S. 登録日 2021-05-23 公開日 2022-05-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.175 Å) 主引用文献 Structure of human DNA polymerase beta complexed with dzA in the template base paired with incoming non-hydrolyzable TTP To Be Published
7MZ0	Structure of human DNA polymerase beta complexed with dzA as the template base in a 1-nucleotide gapped DNA 分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*(4DU)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... 著者 Koag, M.-C, Lee, S. 登録日 2021-05-23 公開日 2022-05-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.021 Å) 主引用文献 Structure Of Human Dna Polymerase Beta Complexed With dzA As The Template Base In A 1-Nucleotide Gapped Dna To Be Published
4Z6F	Structure of human DNA polymerase beta 279NA mutant complexed with G in the template base paired with incoming non-hydrolyzable TTP and MANGANESE 分子名称: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*CP*CP*GP*AP*CP*(6OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... 著者 Koag, M.-C, Lee, S. 登録日 2015-04-04 公開日 2016-04-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.444 Å) 主引用文献 Insights into the effect of minor groove interactions and metal cofactors on mutagenic replication by human DNA polymerase beta. Biochem. J., 475, 2018
7MZ4	Structure of human DNA polymerase beta complexed with 3-deaza-3-methyladenine (3dMeA) in the template base paired with incoming dTTP 分子名称: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*CP*CP*GP*AP*CP*(DZM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... 著者 Koag, M.-C, Lee, S. 登録日 2021-05-24 公開日 2022-06-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.076 Å) 主引用文献 Structure of human DNA polymerase beta complexed with 3-deaza-3-methyladenine (3dMeA) in the template base paired with incoming dTTP To Be Published
5TUS	Potent competitive inhibition of human ribonucleotide reductase by a novel non-nucleoside small molecule 分子名称: 2-hydroxy-N'-[(Z)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large subunit, ... 著者 Mohammed, F.A, Alam, I, Dealwis, C.G. 登録日 2016-11-07 公開日 2017-08-02 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Potent competitive inhibition of human ribonucleotide reductase by a nonnucleoside small molecule. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7MZ8	Structure of human DNA polymerase beta complexed with 3-deaza-3-methyladenine (3dMeA) at N-1 of the template base paired with incoming dTTP 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*CP*GP*AP*CP*GP*(DZM)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*T)-3'), ... 著者 Koag, M.-C, Lee, S. 登録日 2021-05-24 公開日 2022-06-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure Of Human Dna Polymerase Beta Complexed With 8Oa As The Template Base In A 1-Nucleotide Gapped Dna To Be Published
7MZ3	Structure of human DNA polymerase beta complexed with 3-deaza-3-methyladenine (3dMeA) as the template base in a 1-nucleotide gapped DNA 分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*(DZM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... 著者 Koag, M.-C, Lee, S. 登録日 2021-05-24 公開日 2022-06-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.418 Å) 主引用文献 Structure of human DNA polymerase beta complexed with 3-deaza-3-methyladenine (3dMeA) as the template base in a 1-nucleotide gapped DNA To Be Published
7JXY	Structure of TTBK1 kinase domain in complex with Compound 18 分子名称: (3S)-1-[1-(2-aminopyrimidin-4-yl)-1H-pyrazolo[4,3-c]pyridin-6-yl]-3-methylpent-1-yn-3-ol, Tau-tubulin kinase 1 著者 Chodaprambil, J.V. 登録日 2020-08-28 公開日 2021-05-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Discovery of Potent and Brain-Penetrant Tau Tubulin Kinase 1 (TTBK1) Inhibitors that Lower Tau Phosphorylation In Vivo. J.Med.Chem., 64, 2021
2WHW	Selective oxidation of carbolide C-H bonds by engineered macrolide P450 monooxygenase 分子名称: CYCLOTRIDECYL 3,4,6-TRIDEOXY-3-(DIMETHYLAMINO)-BETA-D-XYLO-HEXOPYRANOSIDE, CYTOCHROME P450 MONOOXYGENASE, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Li, S, Chaulagain, M.R, Knauff, A.R, Podust, L.M, Montgomery, J, Sherman, D.H. 登録日 2009-05-07 公開日 2009-10-27 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Selective Oxidation of Carbolide C-H Bonds by an Engineered Macrolide P450 Mono-Oxygenase. Proc.Natl.Acad.Sci.USA, 106, 2009
5Y4U	Crystal structure of Grx domain of Grx3 from Saccharomyces cerevisiae 分子名称: Monothiol glutaredoxin-3 著者 Chi, C.B, Tang, Y.J, Zhang, J.H, Dai, Y.N, Abdalla, M, Chen, Y.X, Zhou, C.Z. 登録日 2017-08-05 公開日 2018-08-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural and Biochemical Insights into the Multiple Functions of Yeast Grx3. J.Mol.Biol., 430, 2018
4ZJ7	Crystal structure of the karyopherin Kap121p bound to the extreme C-terminus of the protein phosphatase Cdc14p 分子名称: Importin subunit beta-3, Tyrosine-protein phosphatase CDC14 著者 Kobayashi, J, Hirano, H, Matsuura, Y. 登録日 2015-04-29 公開日 2015-06-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of the karyopherin Kap121p bound to the extreme C-terminus of the protein phosphatase Cdc14p Biochem.Biophys.Res.Commun., 463, 2015
7JSR	Crystal structure of the large glutamate dehydrogenase composed of 180 kDa subunits from Mycobacterium smegmatis 分子名称: NAD-specific glutamate dehydrogenase 著者 Lazaro, M, Melero, R, Huet, C, Lopez-Alonso, J.P, Delgado, S, Dodu, A, Bruch, E.M, Abriata, L.A, Alzari, P.M, Valle, M, Lisa, M.N. 登録日 2020-08-15 公開日 2021-06-09 最終更新日 2025-05-14 実験手法 X-RAY DIFFRACTION (6.27 Å) 主引用文献 3D architecture and structural flexibility revealed in the subfamily of large glutamate dehydrogenases by a mycobacterial enzyme. Commun Biol, 4, 2021
4FUW	Crystal structure of Ego3 mutant 分子名称: Protein SLM4, SULFATE ION 著者 Zhang, T, Peli-Gulli, M.P, Yang, H, De Virgilio, C, Ding, J. 登録日 2012-06-28 公開日 2012-11-28 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Ego3 functions as a homodimer to mediate the interaction between Gtr1-Gtr2 and Ego1 in the ego complex to activate TORC1. Structure, 20, 2012
5Y4G	Apo Structure of AmbP3 分子名称: AmbP3 著者 Wong, C.P, Awakawa, T, Nakashima, Y. 登録日 2017-08-03 公開日 2018-07-18 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Two Distinct Substrate Binding Modes for the Normal and Reverse Prenylation of Hapalindoles by the Prenyltransferase AmbP3 Angew. Chem. Int. Ed. Engl., 57, 2018
4TGF	SOLUTION STRUCTURES OF HUMAN TRANSFORMING GROWTH FACTOR ALPHA DERIVED FROM 1*H NMR DATA 分子名称: DES-VAL-1,VAL-2,TRANSFORMING GROWTH FACTOR, ALPHA 著者 Kline, T.P, Brown, F.K, Brown, S.C, Jeffs, P.W, Kopple, K.D, Mueller, L. 登録日 1990-06-13 公開日 1991-10-15 最終更新日 2024-11-20 実験手法 SOLUTION NMR 主引用文献 Solution structures of human transforming growth factor alpha derived from 1H NMR data. Biochemistry, 29, 1990
4FDJ	The molecular basis of mucopolysaccharidosis IV A, complex with GalNAc 分子名称: 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Rivera-Colon, Y, Garman, S.C. 登録日 2012-05-28 公開日 2012-09-05 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 The Structure of Human GALNS Reveals the Molecular Basis for Mucopolysaccharidosis IV A. J.Mol.Biol., 423, 2012
2WLC	Crystallographic analysis of the polysialic acid O-acetyltransferase OatWY 分子名称: 1,2-ETHANEDIOL, ACETATE ION, PHOSPHATE ION, ... 著者 Lee, H.J, Rakic, B, Gilbert, M, Wakarchuk, W.W, Withers, S.G, Strynadka, N.C.J. 登録日 2009-06-23 公開日 2009-06-30 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural and Kinetic Characterizations of the Polysialic Acid O-Acetyltransferase Oatwy from Neisseria Meningitidis. J.Biol.Chem., 284, 2009
5UIN	X-ray structure of the W305A variant of the FdtF N-formyltransferase from salmonella enteric O60 分子名称: CHLORIDE ION, Formyltransferase, N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid, ... 著者 Woodford, C.R, Thoden, J.B, Holden, H.M. 登録日 2017-01-14 公開日 2017-03-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Molecular architecture of an N-formyltransferase from Salmonella enterica O60. J. Struct. Biol., 200, 2017
5UIL	X-ray structure of the FdtF N-formyltransferase from Salmonella enterica O60 in complex with TDP-Fuc3N and tetrahydrofolate 分子名称: (3R,4S,5R,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl][hydroxy-[[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate, Formyltransferase, N-[4-({[(6R)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, ... 著者 Woodford, C.R, Thoden, J.B, Holden, H.M. 登録日 2017-01-14 公開日 2017-03-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Molecular architecture of an N-formyltransferase from Salmonella enterica O60. J. Struct. Biol., 200, 2017
4TPH	Selectivity mechanism of a bacterial homologue of the human drug peptide transporters PepT1 and PepT2 分子名称: 3,5 DIBROMOTYROSINE, ALANINE, DODECYL-BETA-D-MALTOSIDE, ... 著者 Guettou, F, Quistgaard, E, Raba, M, Moberg, P, Low, C, Nordlund, P. 登録日 2014-06-07 公開日 2014-07-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.155 Å) 主引用文献 Selectivity mechanism of a bacterial homolog of the human drug-peptide transporters PepT1 and PepT2. Nat.Struct.Mol.Biol., 21, 2014
4RP5	Crystal Structure of the L27 domain of Discs Large 1 (target ID NYSGRC-010766) from Drosophila melanogaster (space group P21) 分子名称: CHLORIDE ION, Disks large 1 tumor suppressor protein 著者 Ghosh, A, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2014-10-29 公開日 2014-11-26 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structures of the L27 Domain of Disc Large Homologue 1 Protein Illustrate a Self-Assembly Module. Biochemistry, 57, 2018

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