8WCR
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![BU of 8wcr by Molmil](/molmil-images/mine/8wcr) | Cryo-EM structure of nanodisc (PE:PS:PC) reconstituted GLIC at pH 4 in open state | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CHLORIDE ION, Proton-gated ion channel | 著者 | Bharambe, N, Li, Z, Basak, S. | 登録日 | 2023-09-13 | 公開日 | 2024-04-17 | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | 主引用文献 | Cryo-EM structures of prokaryotic ligand-gated ion channel GLIC provide insights into gating in a lipid environment. Nat Commun, 15, 2024
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8WCQ
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![BU of 8wcq by Molmil](/molmil-images/mine/8wcq) | Cryo-EM structure of nanodisc (PE:PS:PC) reconstituted GLIC at pH 4 in intermediate state | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CHLORIDE ION, Proton-gated ion channel | 著者 | Bharambe, N, Li, Z, Basak, S. | 登録日 | 2023-09-13 | 公開日 | 2024-04-17 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | Cryo-EM structures of prokaryotic ligand-gated ion channel GLIC provide insights into gating in a lipid environment. Nat Commun, 15, 2024
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3OTF
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![BU of 3otf by Molmil](/molmil-images/mine/3otf) | Structural basis for the cAMP-dependent gating in human HCN4 channel | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | 著者 | Xu, X, Vysotskaya, Z.V, Liu, Q, Zhou, L. | 登録日 | 2010-09-11 | 公開日 | 2010-10-13 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis for the cAMP-dependent gating in the human HCN4 channel. J.Biol.Chem., 285, 2010
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5VKQ
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![BU of 5vkq by Molmil](/molmil-images/mine/5vkq) | Structure of a mechanotransduction ion channel Drosophila NOMPC in nanodisc | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, No mechanoreceptor potential C isoform L | 著者 | Jin, P, Bulkley, D, Guo, Y, Zhang, W, Guo, Z, Huynh, W, Wu, S, Meltzer, S, Chen, T, Jan, L.Y, Jan, Y.-N, Cheng, Y. | 登録日 | 2017-04-22 | 公開日 | 2017-06-28 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.55 Å) | 主引用文献 | Electron cryo-microscopy structure of the mechanotransduction channel NOMPC. Nature, 547, 2017
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3MT5
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![BU of 3mt5 by Molmil](/molmil-images/mine/3mt5) | |
6MC9
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4L11
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![BU of 4l11 by Molmil](/molmil-images/mine/4l11) | |
5WJ9
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![BU of 5wj9 by Molmil](/molmil-images/mine/5wj9) | Human TRPML1 channel structure in agonist-bound open conformation | 分子名称: | 2-{2-oxo-2-[(4S)-2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl]ethyl}-1H-isoindole-1,3(2H)-dione, Mucolipin-1 | 著者 | Schmiege, P, Li, X. | 登録日 | 2017-07-21 | 公開日 | 2017-10-18 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | 主引用文献 | Human TRPML1 channel structures in open and closed conformations. Nature, 550, 2017
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1PX9
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![BU of 1px9 by Molmil](/molmil-images/mine/1px9) | Solution structure of the native CnErg1 Ergtoxin, a highly specific inhibitor of HERG channel | 分子名称: | ergtoxin | 著者 | Frenal, K, Wecker, K, Gurrola, G.B, Possani, L.D, Wolff, N, Delepierre, M. | 登録日 | 2003-07-03 | 公開日 | 2004-06-22 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Exploring structural features of the interaction between the scorpion toxinCnErg1 and ERG K+ channels. Proteins, 56, 2004
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5WJ5
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7YO4
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4RO0
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![BU of 4ro0 by Molmil](/molmil-images/mine/4ro0) | Crystal structure of MthK gating ring in a ligand-free form | 分子名称: | Calcium-gated potassium channel MthK | 著者 | Dong, W, Guo, R, Chai, H, Chen, Z, Cui, H, Ren, Z, Li, Y, Ye, S. | 登録日 | 2014-10-27 | 公開日 | 2015-10-28 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | 主引用文献 | The principle of cooperative gating in a calcium-gated K+ channel To be Published
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4HBN
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![BU of 4hbn by Molmil](/molmil-images/mine/4hbn) | Crystal structure of the human HCN4 channel C-terminus carrying the S672R mutation | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, PHOSPHATE ION, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | 著者 | Xu, X, Marni, F, Wu, X, Su, Z, Musayev, F, Shrestha, S, Xie, C, Gao, W, Liu, Q, Zhou, L. | 登録日 | 2012-09-28 | 公開日 | 2013-01-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Local and Global Interpretations of a Disease-Causing Mutation near the Ligand Entry Path in Hyperpolarization-Activated cAMP-Gated Channel. Structure, 20, 2012
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4DJC
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![BU of 4djc by Molmil](/molmil-images/mine/4djc) | 1.35 A crystal structure of the NaV1.5 DIII-IV-Ca/CaM complex | 分子名称: | CALCIUM ION, Calmodulin, ISOPROPYL ALCOHOL, ... | 著者 | Sarhan, M.F, Tung, C.-C, Van Petegem, F, Ahern, C.A. | 登録日 | 2012-02-01 | 公開日 | 2012-02-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Crystallographic basis for calcium regulation of sodium channels. Proc.Natl.Acad.Sci.USA, 109, 2012
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7YNZ
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7YO0
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7YO1
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3U10
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![BU of 3u10 by Molmil](/molmil-images/mine/3u10) | Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | 著者 | Lolicato, M, Nardini, M, Gazzarrini, S, Moller, S, Bertinetti, D, Herberg, F.W, Bolognesi, M, Martin, H, Fasolini, M, Bertrand, J.A, Arrigoni, C, Thiel, G, Moroni, A. | 登録日 | 2011-09-29 | 公開日 | 2011-10-26 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels. J.Biol.Chem., 286, 2011
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1ROO
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![BU of 1roo by Molmil](/molmil-images/mine/1roo) | NMR SOLUTION STRUCTURE OF SHK TOXIN, NMR, 20 STRUCTURES | 分子名称: | SHK TOXIN | 著者 | Tudor, J.E, Pallaghy, P.K, Pennington, M.W, Norton, R.S. | 登録日 | 1996-01-11 | 公開日 | 1997-01-27 | 最終更新日 | 2017-11-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of ShK toxin, a novel potassium channel inhibitor from a sea anemone. Nat.Struct.Biol., 3, 1996
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1WVR
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![BU of 1wvr by Molmil](/molmil-images/mine/1wvr) | Crystal Structure of a CRISP family Ca-channel blocker derived from snake venom | 分子名称: | CADMIUM ION, Triflin | 著者 | Shikamoto, Y, Suto, K, Yamazaki, Y, Morita, T, Mizuno, H. | 登録日 | 2004-12-24 | 公開日 | 2005-07-05 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of a CRISP family Ca2+ -channel blocker derived from snake venom. J.Mol.Biol., 350, 2005
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2F3Z
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![BU of 2f3z by Molmil](/molmil-images/mine/2f3z) | Calmodulin/IQ-AA domain complex | 分子名称: | CALCIUM ION, Calmodulin, Voltage-dependent L-type calcium channel alpha-1C subunit | 著者 | Fallon, J.L, Quiocho, F.A. | 登録日 | 2005-11-22 | 公開日 | 2005-12-27 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure of Calmodulin Bound to the Hydrophobic IQ Domain of the Cardiac Ca(v)1.2 Calcium Channel. Structure, 13, 2005
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2F3Y
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![BU of 2f3y by Molmil](/molmil-images/mine/2f3y) | Calmodulin/IQ domain complex | 分子名称: | CALCIUM ION, Calmodulin, MAGNESIUM ION, ... | 著者 | Fallon, J.L, Quiocho, F.A. | 登録日 | 2005-11-22 | 公開日 | 2005-12-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structure of Calmodulin Bound to the Hydrophobic IQ Domain of the Cardiac Ca(v)1.2 Calcium Channel. Structure, 13, 2005
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3U11
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![BU of 3u11 by Molmil](/molmil-images/mine/3u11) | Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GLYCEROL, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | 著者 | Lolicato, M, Nardini, M, Gazzarrini, S, Moller, S, Bertinetti, D, Herberg, F.W, Bolognesi, M, Martin, H, Fasolini, M, Bertrand, J.A, Arrigoni, C, Thiel, G, Moroni, A. | 登録日 | 2011-09-29 | 公開日 | 2011-10-26 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels. J.Biol.Chem., 286, 2011
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5YE1
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3TLW
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![BU of 3tlw by Molmil](/molmil-images/mine/3tlw) | The GLIC pentameric Ligand-Gated Ion Channel Loop2-21' oxidized mutant in a locally-closed conformation (LC2 subtype) | 分子名称: | CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Glr4197 protein | 著者 | Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. | 登録日 | 2011-08-30 | 公開日 | 2012-05-16 | 最終更新日 | 2012-06-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | A locally closed conformation of a bacterial pentameric proton-gated ion channel. Nat.Struct.Mol.Biol., 19, 2012
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