8WCR
 
 | | Cryo-EM structure of nanodisc (PE:PS:PC) reconstituted GLIC at pH 4 in open state | | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CHLORIDE ION, Proton-gated ion channel | | 著者 | Bharambe, N, Li, Z, Basak, S. | | 登録日 | 2023-09-13 | | 公開日 | 2024-04-17 | | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | | 主引用文献 | Cryo-EM structures of prokaryotic ligand-gated ion channel GLIC provide insights into gating in a lipid environment.
Nat Commun, 15, 2024
|
|
8WCQ
 | | Cryo-EM structure of nanodisc (PE:PS:PC) reconstituted GLIC at pH 4 in intermediate state | | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CHLORIDE ION, Proton-gated ion channel | | 著者 | Bharambe, N, Li, Z, Basak, S. | | 登録日 | 2023-09-13 | | 公開日 | 2024-04-17 | | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | | 主引用文献 | Cryo-EM structures of prokaryotic ligand-gated ion channel GLIC provide insights into gating in a lipid environment.
Nat Commun, 15, 2024
|
|
3OTF
 | | Structural basis for the cAMP-dependent gating in human HCN4 channel | | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | | 著者 | Xu, X, Vysotskaya, Z.V, Liu, Q, Zhou, L. | | 登録日 | 2010-09-11 | | 公開日 | 2010-10-13 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for the cAMP-dependent gating in the human HCN4 channel.
J.Biol.Chem., 285, 2010
|
|
5VKQ
 | | Structure of a mechanotransduction ion channel Drosophila NOMPC in nanodisc | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, No mechanoreceptor potential C isoform L | | 著者 | Jin, P, Bulkley, D, Guo, Y, Zhang, W, Guo, Z, Huynh, W, Wu, S, Meltzer, S, Chen, T, Jan, L.Y, Jan, Y.-N, Cheng, Y. | | 登録日 | 2017-04-22 | | 公開日 | 2017-06-28 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.55 Å) | | 主引用文献 | Electron cryo-microscopy structure of the mechanotransduction channel NOMPC.
Nature, 547, 2017
|
|
3MT5
 | |
6MC9
 | |
4L11
 | |
5WJ9
 | | Human TRPML1 channel structure in agonist-bound open conformation | | 分子名称: | 2-{2-oxo-2-[(4S)-2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl]ethyl}-1H-isoindole-1,3(2H)-dione, Mucolipin-1 | | 著者 | Schmiege, P, Li, X. | | 登録日 | 2017-07-21 | | 公開日 | 2017-10-18 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | | 主引用文献 | Human TRPML1 channel structures in open and closed conformations.
Nature, 550, 2017
|
|
1PX9
 | | Solution structure of the native CnErg1 Ergtoxin, a highly specific inhibitor of HERG channel | | 分子名称: | ergtoxin | | 著者 | Frenal, K, Wecker, K, Gurrola, G.B, Possani, L.D, Wolff, N, Delepierre, M. | | 登録日 | 2003-07-03 | | 公開日 | 2004-06-22 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Exploring structural features of the interaction between the scorpion toxinCnErg1 and ERG K+ channels.
Proteins, 56, 2004
|
|
5WJ5
 | |
7YO4
 | |
4RO0
 | | Crystal structure of MthK gating ring in a ligand-free form | | 分子名称: | Calcium-gated potassium channel MthK | | 著者 | Dong, W, Guo, R, Chai, H, Chen, Z, Cui, H, Ren, Z, Li, Y, Ye, S. | | 登録日 | 2014-10-27 | | 公開日 | 2015-10-28 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | | 主引用文献 | The principle of cooperative gating in a calcium-gated K+ channel
To be Published
|
|
4HBN
 | | Crystal structure of the human HCN4 channel C-terminus carrying the S672R mutation | | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, PHOSPHATE ION, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | | 著者 | Xu, X, Marni, F, Wu, X, Su, Z, Musayev, F, Shrestha, S, Xie, C, Gao, W, Liu, Q, Zhou, L. | | 登録日 | 2012-09-28 | | 公開日 | 2013-01-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Local and Global Interpretations of a Disease-Causing Mutation near the Ligand Entry Path in Hyperpolarization-Activated cAMP-Gated Channel.
Structure, 20, 2012
|
|
4DJC
 | | 1.35 A crystal structure of the NaV1.5 DIII-IV-Ca/CaM complex | | 分子名称: | CALCIUM ION, Calmodulin, ISOPROPYL ALCOHOL, ... | | 著者 | Sarhan, M.F, Tung, C.-C, Van Petegem, F, Ahern, C.A. | | 登録日 | 2012-02-01 | | 公開日 | 2012-02-22 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Crystallographic basis for calcium regulation of sodium channels.
Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
7YNZ
 | |
7YO0
 | |
7YO1
 | |
3U10
 | | Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels | | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | | 著者 | Lolicato, M, Nardini, M, Gazzarrini, S, Moller, S, Bertinetti, D, Herberg, F.W, Bolognesi, M, Martin, H, Fasolini, M, Bertrand, J.A, Arrigoni, C, Thiel, G, Moroni, A. | | 登録日 | 2011-09-29 | | 公開日 | 2011-10-26 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.
J.Biol.Chem., 286, 2011
|
|
1ROO
 | | NMR SOLUTION STRUCTURE OF SHK TOXIN, NMR, 20 STRUCTURES | | 分子名称: | SHK TOXIN | | 著者 | Tudor, J.E, Pallaghy, P.K, Pennington, M.W, Norton, R.S. | | 登録日 | 1996-01-11 | | 公開日 | 1997-01-27 | | 最終更新日 | 2017-11-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of ShK toxin, a novel potassium channel inhibitor from a sea anemone.
Nat.Struct.Biol., 3, 1996
|
|
1WVR
 | | Crystal Structure of a CRISP family Ca-channel blocker derived from snake venom | | 分子名称: | CADMIUM ION, Triflin | | 著者 | Shikamoto, Y, Suto, K, Yamazaki, Y, Morita, T, Mizuno, H. | | 登録日 | 2004-12-24 | | 公開日 | 2005-07-05 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of a CRISP family Ca2+ -channel blocker derived from snake venom.
J.Mol.Biol., 350, 2005
|
|
2F3Z
 | | Calmodulin/IQ-AA domain complex | | 分子名称: | CALCIUM ION, Calmodulin, Voltage-dependent L-type calcium channel alpha-1C subunit | | 著者 | Fallon, J.L, Quiocho, F.A. | | 登録日 | 2005-11-22 | | 公開日 | 2005-12-27 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure of Calmodulin Bound to the Hydrophobic IQ Domain of the Cardiac Ca(v)1.2 Calcium Channel.
Structure, 13, 2005
|
|
2F3Y
 | | Calmodulin/IQ domain complex | | 分子名称: | CALCIUM ION, Calmodulin, MAGNESIUM ION, ... | | 著者 | Fallon, J.L, Quiocho, F.A. | | 登録日 | 2005-11-22 | | 公開日 | 2005-12-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structure of Calmodulin Bound to the Hydrophobic IQ Domain of the Cardiac Ca(v)1.2 Calcium Channel.
Structure, 13, 2005
|
|
3U11
 | | Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels | | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GLYCEROL, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | | 著者 | Lolicato, M, Nardini, M, Gazzarrini, S, Moller, S, Bertinetti, D, Herberg, F.W, Bolognesi, M, Martin, H, Fasolini, M, Bertrand, J.A, Arrigoni, C, Thiel, G, Moroni, A. | | 登録日 | 2011-09-29 | | 公開日 | 2011-10-26 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.
J.Biol.Chem., 286, 2011
|
|
5YE1
 | |
3TLW
 | | The GLIC pentameric Ligand-Gated Ion Channel Loop2-21' oxidized mutant in a locally-closed conformation (LC2 subtype) | | 分子名称: | CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Glr4197 protein | | 著者 | Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. | | 登録日 | 2011-08-30 | | 公開日 | 2012-05-16 | | 最終更新日 | 2012-06-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A locally closed conformation of a bacterial pentameric proton-gated ion channel.
Nat.Struct.Mol.Biol., 19, 2012
|
|
