6Y53
| human 17S U2 snRNP low resolution part | 分子名称: | HIV Tat-specific factor 1, Probable ATP-dependent RNA helicase DDX46, Small nuclear ribonucleoprotein E, ... | 著者 | Zhang, Z, Will, C.L, Bertram, K, Luehrmann, R, Stark, H. | 登録日 | 2020-02-24 | 公開日 | 2020-06-17 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (7.1 Å) | 主引用文献 | Molecular architecture of the human 17S U2 snRNP. Nature, 583, 2020
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7Q4O
| Substrate-bound A-like U2 snRNP | 分子名称: | BPS oligo, PHD finger-like domain-containing protein 5A, Splicing factor 3A subunit 2, ... | 著者 | Tholen, J, Galej, W.P. | 登録日 | 2021-11-01 | 公開日 | 2022-03-30 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.1 Å) | 主引用文献 | Structural basis of branch site recognition by the human spliceosome. Science, 375, 2022
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7Q4P
| U2 snRNP after ATP-dependent remodelling | 分子名称: | PHD finger-like domain-containing protein 5A, Splicing factor 3A subunit 2, Splicing factor 3A subunit 3, ... | 著者 | Tholen, J, Galej, W.P. | 登録日 | 2021-11-01 | 公開日 | 2022-03-30 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.15 Å) | 主引用文献 | Structural basis of branch site recognition by the human spliceosome. Science, 375, 2022
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6Y5Q
| human 17S U2 snRNP | 分子名称: | HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ... | 著者 | Zhang, Z, Will, C.L, Bertram, K, Luehrmann, R, Stark, H. | 登録日 | 2020-02-25 | 公開日 | 2020-06-17 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (7.1 Å) | 主引用文献 | Molecular architecture of the human 17S U2 snRNP. Nature, 583, 2020
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8G5M
| Cryo-EM structure of the Mismatch Locking Complex (III) of Human Mitochondrial DNA Polymerase Gamma | 分子名称: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | 著者 | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | 登録日 | 2023-02-13 | 公開日 | 2024-01-10 | 実験手法 | ELECTRON MICROSCOPY (2.58 Å) | 主引用文献 | Structural basis for DNA proofreading. Nat Commun, 14, 2023
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7OZV
| SARS-CoV-2 RdRp with Molnupiravir/ NHC in the template strand base-paired with G | 分子名称: | Non-structural protein 7, Non-structural protein 8, Product RNA, ... | 著者 | Kabinger, F, Stiller, C, Schmitzova, J, Dienemann, C, Kokic, G, Hillen, H.S, Hoebartner, C, Cramer, P. | 登録日 | 2021-06-28 | 公開日 | 2021-08-18 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis. Nat.Struct.Mol.Biol., 28, 2021
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7OZU
| SARS-CoV-2 RdRp with Molnupiravir/ NHC in the template strand base-paired with A | 分子名称: | Non-structural protein 7, Non-structural protein 8, Product RNA, ... | 著者 | Kabinger, F, Stiller, C, Schmitzova, J, Dienemann, C, Kokic, G, Hillen, H.S, Hoebartner, C, Cramer, P. | 登録日 | 2021-06-28 | 公開日 | 2021-08-18 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis. Nat.Struct.Mol.Biol., 28, 2021
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6Y50
| 5'domain of human 17S U2 snRNP | 分子名称: | HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ... | 著者 | Zhang, Z, Will, C.L, Bertram, K, Luehrmann, R, Stark, H. | 登録日 | 2020-02-24 | 公開日 | 2020-07-01 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Molecular architecture of the human 17S U2 snRNP. Nature, 583, 2020
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7DVQ
| Cryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex) | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, 5'-O-[(S)-hydroxy{[(R)-hydroxy{[(S)-hydroxy(methoxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]guanosine, Armadillo repeat-containing protein 7, ... | 著者 | Bai, R, Wan, R, Wang, L, Xu, K, Zhang, Q, Lei, J, Shi, Y. | 登録日 | 2021-01-14 | 公開日 | 2021-03-31 | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | 主引用文献 | Structure of the activated human minor spliceosome. Science, 371, 2021
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6Q8Y
| Cryo-EM structure of the mRNA translating and degrading yeast 80S ribosome-Xrn1 nuclease complex | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Tesina, P, Heckel, E, Cheng, J, Buschauer, R, Kater, L, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2018-12-16 | 公開日 | 2019-03-13 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure of the 80S ribosome-Xrn1 nuclease complex. Nat.Struct.Mol.Biol., 26, 2019
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6FF7
| human Bact spliceosome core structure | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, BUD13 homolog, ... | 著者 | Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. | 登録日 | 2018-01-03 | 公開日 | 2019-03-13 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structure and Conformational Dynamics of the Human Spliceosomal BactComplex. Cell, 172, 2018
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6FF4
| human Bact spliceosome core structure | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | 著者 | Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. | 登録日 | 2018-01-03 | 公開日 | 2018-08-29 | 最終更新日 | 2020-10-07 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure and Conformational Dynamics of the Human Spliceosomal BactComplex. Cell, 172, 2018
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5Z57
| Cryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstrom | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ALANINE, BUD13 homolog, ... | 著者 | Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. | 登録日 | 2018-01-17 | 公開日 | 2018-09-19 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | 主引用文献 | Structure of the human activated spliceosome in three conformational states. Cell Res., 28, 2018
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7VPX
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8K82
| Cryo-EM structure of the yeast 80S ribosome with tigecycline, Not5 and P-site tRNA | 分子名称: | 18S rRNA, 23S rRNA, 40S ribosomal protein S1-A, ... | 著者 | Buschauer, R, Beckmann, R, Cheng, J. | 登録日 | 2023-07-28 | 公開日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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4UCI
| X-ray structure and activities of an essential Mononegavirales L- protein domain | 分子名称: | ADENOSINE, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Paesen, G.C, Collet, A, Sallamand, C, Debart, F, Vasseur, J.J, Canard, B, Decroly, E, Grimes, J.M. | 登録日 | 2014-12-03 | 公開日 | 2015-10-14 | 最終更新日 | 2019-04-24 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain. Nat.Commun., 6, 2015
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4UCZ
| X-ray structure and activities of an essential Mononegavirales L- protein domain | 分子名称: | GUANOSINE, GUANOSINE-5'-TRIPHOSPHATE, RNA-DIRECTED RNA POLYMERASE L, ... | 著者 | Paesen, G.C, Collet, A, Sallamand, C, Debart, F, Vasseur, J.J, Canard, B, Decroly, E, Grimes, J.M. | 登録日 | 2014-12-05 | 公開日 | 2015-11-18 | 最終更新日 | 2019-04-24 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain. Nat.Commun., 6, 2015
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7EVO
| The cryo-EM structure of the human 17S U2 snRNP | 分子名称: | HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, RNA helicase, ... | 著者 | Zhang, X, Zhan, X, Shi, Y. | 登録日 | 2021-05-21 | 公開日 | 2022-08-03 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structural insights into branch site proofreading by human spliceosome. Nat.Struct.Mol.Biol., 2024
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5FUR
| Structure of human TFIID-IIA bound to core promoter DNA | 分子名称: | SUPER CORE PROMOTER, TATA-BOX-BINDING PROTEIN, TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1, ... | 著者 | Louder, R.K, He, Y, Lopez-Blanco, J.R, Fang, J, Chacon, P, Nogales, E. | 登録日 | 2016-01-29 | 公開日 | 2016-04-06 | 最終更新日 | 2017-08-02 | 実験手法 | ELECTRON MICROSCOPY (8.5 Å) | 主引用文献 | Structure of Promoter-Bound TFIID and Model of Human Pre-Initiation Complex Assembly. Nature, 531, 2016
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7AMV
| Atomic structure of the poxvirus transcription pre-initiation complex in the initially melted state | 分子名称: | ATP-dependent helicase VETFS, DNA-directed RNA polymerase, DNA-directed RNA polymerase 147 kDa polypeptide, ... | 著者 | Grimm, C, Bartuli, J, Fischer, U. | 登録日 | 2020-10-09 | 公開日 | 2021-10-06 | 最終更新日 | 2021-10-20 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis of the complete poxvirus transcription initiation process. Nat.Struct.Mol.Biol., 28, 2021
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7AOF
| Atomic structure of the poxvirus transcription late pre-initiation complex | 分子名称: | DNA-directed RNA polymerase, DNA-directed RNA polymerase 147 kDa polypeptide, DNA-directed RNA polymerase 18 kDa subunit, ... | 著者 | Grimm, C, Bartuli, J, Fischer, U. | 登録日 | 2020-10-14 | 公開日 | 2021-10-06 | 最終更新日 | 2021-10-20 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | Structural basis of the complete poxvirus transcription initiation process. Nat.Struct.Mol.Biol., 28, 2021
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7AP8
| Atomic structure of the poxvirus initially transcribing complex in conformation 2 | 分子名称: | DNA-directed RNA polymerase, DNA-directed RNA polymerase 147 kDa polypeptide, DNA-directed RNA polymerase 18 kDa subunit, ... | 著者 | Grimm, C, Bartuli, J, Fischer, U. | 登録日 | 2020-10-16 | 公開日 | 2021-10-06 | 最終更新日 | 2021-10-20 | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | 主引用文献 | Structural basis of the complete poxvirus transcription initiation process. Nat.Struct.Mol.Biol., 28, 2021
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7AOZ
| Atomic structure of the poxvirus transcription initiation complex in conformation 1 | 分子名称: | DNA-directed RNA polymerase, DNA-directed RNA polymerase 147 kDa polypeptide, DNA-directed RNA polymerase 18 kDa subunit, ... | 著者 | Grimm, C, Bartuli, J, Fischer, U. | 登録日 | 2020-10-15 | 公開日 | 2021-10-06 | 最終更新日 | 2021-10-20 | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | 主引用文献 | Structural basis of the complete poxvirus transcription initiation process. Nat.Struct.Mol.Biol., 28, 2021
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7AOH
| Atomic structure of the poxvirus late initially transcribing complex | 分子名称: | DNA-directed RNA polymerase, DNA-directed RNA polymerase 147 kDa polypeptide, DNA-directed RNA polymerase 18 kDa subunit, ... | 著者 | Grimm, C, Bartuli, J, Fischer, U. | 登録日 | 2020-10-14 | 公開日 | 2021-10-06 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structural basis of the complete poxvirus transcription initiation process. Nat.Struct.Mol.Biol., 28, 2021
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7AP9
| Atomic structure of the poxvirus initially transcribing complex in conformation 3 | 分子名称: | DNA-directed RNA polymerase, DNA-directed RNA polymerase 147 kDa polypeptide, DNA-directed RNA polymerase 18 kDa subunit, ... | 著者 | Grimm, C, Bartuli, J, Fischer, U. | 登録日 | 2020-10-16 | 公開日 | 2021-10-06 | 最終更新日 | 2021-10-20 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | Structural basis of the complete poxvirus transcription initiation process. Nat.Struct.Mol.Biol., 28, 2021
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