7OZU

SARS-CoV-2 RdRp with Molnupiravir/ NHC in the template strand base-paired with A

Summary for 7OZU

Entry DOI	10.2210/pdb7ozu/pdb
EMDB information	13135
Descriptor	Replicase polyprotein 1ab, Non-structural protein 8, Non-structural protein 7, ... (6 entities in total)
Functional Keywords	sars-cov-2, rna-dependent rna polymerase, molnupiravir (nhc), viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) More
Total number of polymer chains	5
Total formula weight	161134.37
Authors	Kabinger, F.,Stiller, C.,Schmitzova, J.,Dienemann, C.,Kokic, G.,Hillen, H.S.,Hoebartner, C.,Cramer, P. (deposition date: 2021-06-28, release date: 2021-08-18, Last modification date: 2021-09-29)
Primary citation	Kabinger, F.,Stiller, C.,Schmitzova, J.,Dienemann, C.,Kokic, G.,Hillen, H.S.,Hobartner, C.,Cramer, P. Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis. Nat.Struct.Mol.Biol., 28:740-746, 2021 Cited by PubMed: 34381216 DOI: 10.1038/s41594-021-00651-0 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.3 Å)

Structure validation