PDB: 1957 件ウェブページステータス検索Chemie searchBIRD

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7QSA	Structural basis on the interaction of Scribble PDZ domains with the Tick Born encephalitis virus (TBEV) NS5 protein 分子名称: Protein scribble homolog, RNA-directed RNA polymerase NS5 著者 Javorsky, A, Humbert, P.O, Kvansakul, M. 登録日 2022-01-13 公開日 2022-08-31 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Molecular basis of Tick Born encephalitis virus NS5 mediated subversion of apico-basal cell polarity signalling. Biochem.J., 479, 2022
7QS9	Structural basis on the interaction of Scribble PDZ domains with the Tick Born encephalitis virus (TBEV) NS5 protein 分子名称: Protein scribble homolog, RNA-directed RNA polymerase NS5 著者 Javorsky, A, Humbert, P.O, Kvansakul, M. 登録日 2022-01-13 公開日 2022-08-31 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Molecular basis of Tick Born encephalitis virus NS5 mediated subversion of apico-basal cell polarity signalling. Biochem.J., 479, 2022
8GWM	SARS-CoV-2 E-RTC bound with MMP-nsp9 and GMPPNP 分子名称: 2'-deoxy-2'-fluoro-2'-methyluridine 5'-(trihydrogen diphosphate), Helicase, Non-structural protein 7, ... 著者 Yan, L.M, Rao, Z.H, Lou, Z.Y. 登録日 2022-09-17 公開日 2024-02-28 実験手法 ELECTRON MICROSCOPY (2.64 Å) 主引用文献 A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
8GWK	SARS-CoV-2 RNA E-RTC complex with RMP-nsp9 and GMPPNP 分子名称: Helicase, MAGNESIUM ION, Non-structural protein 7, ... 著者 Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. 登録日 2022-09-17 公開日 2024-02-28 実験手法 ELECTRON MICROSCOPY (2.72 Å) 主引用文献 A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
4HXD	Diversity of ubiquitin and ISG15 specificity amongst nairoviruses viral ovarian tumor domain proteases 分子名称: 1.7.6 3-bromanylpropan-1-amine, Polyubiquitin-C, RNA-directed RNA polymerase L, ... 著者 Capodagli, G.C, Pegan, S.D. 登録日 2012-11-09 公開日 2013-02-13 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Diversity of Ubiquitin and ISG15 Specificity among Nairoviruses' Viral Ovarian Tumor Domain Proteases. J.Virol., 87, 2013
8X01	Structure of the Mumps Virus L Protein (state2) Bound by Phosphoprotein Tetramer 分子名称: Phosphoprotein, RNA-directed RNA polymerase L, ZINC ION 著者 Li, T.H, Shen, Q.T. 登録日 2023-11-02 公開日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.01 Å) 主引用文献 Structures of the mumps virus polymerase complex via cryo-electron microscopy. Nat Commun, 15, 2024
8YXM	Structure of N-terminal domain of L protein bound with Phosphoprotein from Mumps Virus 分子名称: Phosphoprotein, RNA-directed RNA polymerase L, ZINC ION 著者 Li, T.H, Shen, Q.T. 登録日 2024-04-02 公開日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.93 Å) 主引用文献 Structures of the mumps virus polymerase complex via cryo-electron microscopy. Nat Commun, 15, 2024
1YN6	Crystal structure of a mouse MHC class I protein, H2-Db, in complex with a peptide from the influenza A acid polymerase 分子名称: 10-mer peptide from RNA-directed RNA polymerase subunit P2, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... 著者 Turner, S.J, Kedzierska, K, Komodromou, H, La Gruta, N.L, Dunstone, M.A, Webb, A.I, Webby, R, Walden, H, Xie, W, McCluskey, J, Purcell, A.W, Rossjohn, J, Doherty, P.C. 登録日 2005-01-23 公開日 2005-06-28 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations Nat.Immunol., 6, 2005
5HHG	Mouse importin alpha: Dengue 2 NS5 C-terminal NLS peptide complex 分子名称: Importin subunit alpha-1, RNA-directed RNA polymerase NS5 著者 Smith, K.M, Forwood, J.K. 登録日 2016-01-11 公開日 2016-05-18 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production. PLoS Pathog., 12, 2016
5V5H	OTU protease of Crimean Congo Hemorrhagic Fever Virus bound to ubiquitin variant CC.2 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, RNA-directed RNA polymerase L, SODIUM ION, ... 著者 Khare, B, Mark, B.L. 登録日 2017-03-14 公開日 2017-05-10 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants. PLoS Pathog., 13, 2017
5V5G	OTU protease of Crimean Congo Hemorrhagic Fever Virus bound to ubiquitin variant CC.4 分子名称: 1,2-ETHANEDIOL, RNA-directed RNA polymerase L, SODIUM ION, ... 著者 Khare, B, Mark, B.L. 登録日 2017-03-14 公開日 2017-05-10 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants. PLoS Pathog., 13, 2017
8V38	Structure of the human systemic RNAi defective transmembrane protein 1 (hSIDT1) 分子名称: SID1 transmembrane family member 1,RNA-directed RNA polymerase L 著者 Navratna, V, Kumar, A, Rana, J.K, Mosalaganti, S. 登録日 2023-11-27 公開日 2024-06-26 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure of the human systemic RNAi defective transmembrane protein 1 (hSIDT1) reveals the conformational flexibility of its lipid binding domain. Biorxiv, 2024
8PEM	Zika Methyltransferase in complex with AT-9010 and SAH 分子名称: MAGNESIUM ION, RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Krejcova, K, Boura, E, Klima, M. 登録日 2023-06-14 公開日 2024-06-26 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of Zika Methyltransferase in complex with AT-9010 and SAH to be published
8W1S	Cryo-EM structure of BTV pre-core 分子名称: Core protein VP3, RNA-directed RNA polymerase 著者 Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H. 登録日 2024-02-17 公開日 2024-04-24 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells. Cell, 187, 2024
8W1R	Cryo-EM structure of BTV core 分子名称: Core protein VP3, RNA-directed RNA polymerase 著者 Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H. 登録日 2024-02-17 公開日 2024-04-24 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells. Cell, 187, 2024
8W1O	Cryo-EM structure of BTV virion 分子名称: Core protein VP3, Outer capsid protein VP2, RNA-1, ... 著者 Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H. 登録日 2024-02-16 公開日 2024-04-24 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells. Cell, 187, 2024
8R1L	Structure of avian H5N1 influenza A polymerase in complex with human ANP32B. 分子名称: Acidic leucine-rich nuclear phosphoprotein 32 family member B, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Carrique, L, Staller, E, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M. 登録日 2023-11-02 公開日 2024-05-08 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structures of H5N1 influenza polymerase with ANP32B reveal mechanisms of genome replication and host adaptation. Nat Commun, 15, 2024
8R1J	Structure of avian H5N1 influenza A polymerase dimer in complex with human ANP32B. 分子名称: Acidic leucine-rich nuclear phosphoprotein 32 family member B, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Carrique, L, Staller, E, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M. 登録日 2023-11-02 公開日 2024-05-08 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structures of H5N1 influenza polymerase with ANP32B reveal mechanisms of genome replication and host adaptation. Nat Commun, 15, 2024
3PRM	Structural analysis of a viral OTU domain protease from the Crimean-Congo Hemorrhagic Fever virus in complex with human ubiquitin 分子名称: Polyubiquitin-B (Fragment), RNA-directed RNA polymerase L 著者 Capodagli, G.C, McKercher, M.A, Baker, E.A, Masters, E.M, Brunzelle, J.S, Pegan, S.D. 登録日 2010-11-30 公開日 2011-01-26 最終更新日 2023-02-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural analysis of a viral ovarian tumor domain protease from the crimean-congo hemorrhagic Fever virus in complex with covalently bonded ubiquitin. J.Virol., 85, 2011
3EVF	Crystal structure of Me7-GpppA complex of yellow fever virus methyltransferase and S-adenosyl-L-homocysteine 分子名称: P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE 著者 Thompson, A.A, Geiss, B.J, Peersen, O.B. 登録日 2008-10-13 公開日 2009-01-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Analysis of flavivirus NS5 methyltransferase cap binding. J.Mol.Biol., 385, 2009
5GP1	Crystal structure of ZIKV NS5 Methyltransferase in complex with GTP and SAH 分子名称: NICKEL (II) ION, P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, RNA-directed RNA polymerase NS5, ... 著者 Zhang, C, Jin, T. 登録日 2016-07-30 公開日 2016-12-07 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (2.444 Å) 主引用文献 Structure of the NS5 methyltransferase from Zika virus and implications in inhibitor design Biochem. Biophys. Res. Commun., 492, 2017
3EVE	Crystal structure of GpppA complex of yellow fever virus methyltransferase and S-adenosyl-L-homocysteine 分子名称: GUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE 著者 Thompson, A.A. 登録日 2008-10-13 公開日 2009-01-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Analysis of flavivirus NS5 methyltransferase cap binding. J.Mol.Biol., 385, 2009
3PRP	Structural analysis of a viral OTU domain protease from the Crimean-Congo Hemorrhagic Fever virus in complex with human ubiquitin 分子名称: Polyubiquitin-B (Fragment), RNA-directed RNA polymerase L 著者 Capodagli, G.C, McKercher, M.A, Baker, E.A, Masters, E.M, Brunzelle, J.S, Pegan, S.D. 登録日 2010-11-30 公開日 2011-01-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.699 Å) 主引用文献 Structural analysis of a viral ovarian tumor domain protease from the crimean-congo hemorrhagic Fever virus in complex with covalently bonded ubiquitin. J.Virol., 85, 2011
5GOZ	Crystal structure of ZIKV NS5 Methyltransferase in complex with GTP and SAH 分子名称: GUANOSINE-5'-TRIPHOSPHATE, PHOSPHATE ION, PYROPHOSPHATE 2-, ... 著者 Zhang, C, Jin, T. 登録日 2016-07-30 公開日 2016-12-07 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (2.049 Å) 主引用文献 Structure of the NS5 methyltransferase from Zika virus and implications in inhibitor design Biochem. Biophys. Res. Commun., 492, 2017
3EVD	Crystal structure of GTP complex of yellow fever virus methyltransferase and S-adenosyl-L-homocysteine 分子名称: GUANOSINE-5'-TRIPHOSPHATE, RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE 著者 Thompson, A.A, Geiss, B.J, Peersen, O.B. 登録日 2008-10-13 公開日 2009-01-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Analysis of flavivirus NS5 methyltransferase cap binding. J.Mol.Biol., 385, 2009

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