8GGJ
 
 | | Locally refined cryoEM structure of receptor from beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #2 of 20) | | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor | | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | | 登録日 | 2023-03-08 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
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8GGK
 | | Locally refined cryoEM structure of receptor from beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #3 of 20) | | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor | | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | | 登録日 | 2023-03-08 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
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8GGL
 | | Locally refined cryoEM structure of receptor from beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #4 of 20) | | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor | | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | | 登録日 | 2023-03-08 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
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8GGM
 | | Locally refined cryoEM structure of receptor from beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #5 of 20) | | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor | | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | | 登録日 | 2023-03-08 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
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8GGN
 | | Locally refined cryoEM structure of receptor from beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #6 of 20) | | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor | | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | | 登録日 | 2023-03-08 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
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8GGO
 | | Locally refined cryoEM structure of receptor from beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #7 of 20) | | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor | | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | | 登録日 | 2023-03-08 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
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8GGP
 | | Locally refined cryoEM structure of receptor from beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #8 of 20) | | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor | | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | | 登録日 | 2023-03-08 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
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8GGQ
 | | Locally refined cryoEM structure of receptor from beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #9 of 20) | | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor | | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | | 登録日 | 2023-03-08 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
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8GGR
 | | Locally refined cryoEM structure of receptor from beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #10 of 20) | | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor | | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | | 登録日 | 2023-03-08 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
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8GGS
 | | Locally refined cryoEM structure of receptor from beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #11 of 20) | | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor | | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | | 登録日 | 2023-03-08 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
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8GGT
 | | Locally refined cryoEM structure of receptor from beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #12 of 20) | | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor | | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | | 登録日 | 2023-03-08 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
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8GGU
 | | Locally refined cryoEM structure of receptor from beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #13 of 20) | | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor | | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | | 登録日 | 2023-03-08 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
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8GGV
 | | Locally refined cryoEM structure of receptor from beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #14 of 20) | | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor | | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | | 登録日 | 2023-03-08 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
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8GGW
 | | Locally refined cryoEM structure of receptor from beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #15 of 20) | | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor | | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | | 登録日 | 2023-03-08 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
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8GGX
 | | Locally refined cryoEM structure of receptor from beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #16 of 20) | | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor | | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | | 登録日 | 2023-03-08 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
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8GGY
 | | Locally refined cryoEM structure of receptor from beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #17 of 20) | | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor | | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | | 登録日 | 2023-03-08 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
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8GGZ
 | | Locally refined cryoEM structure of receptor from beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #18 of 20) | | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor | | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | | 登録日 | 2023-03-08 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
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8GH0
 | | Locally refined cryoEM structure of receptor from beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #19 of 20) | | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor | | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | | 登録日 | 2023-03-08 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
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8GH1
 | | Locally refined cryoEM structure of receptor from beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (transition intermediate #20 of 20) | | 分子名称: | (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor | | 著者 | Papasergi-Scott, M.M, Skiniotis, G. | | 登録日 | 2023-03-08 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
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8GHV
 | | Cannabinoid Receptor 1-G Protein Complex | | 分子名称: | (5Z,8Z,11Z,13S,14Z)-N-[(2R)-1-hydroxypropan-2-yl]-13-methylicosa-5,8,11,14-tetraenamide, Cannabinoid receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Krishna Kumar, K, Robertson, M.J, Skiniotis, G, Kobilka, B.K. | | 登録日 | 2023-03-12 | | 公開日 | 2023-05-24 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural basis for activation of CB1 by an endocannabinoid analog.
Nat Commun, 14, 2023
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8GNE
 | | Crystal structure of human adenosine A2A receptor in complex with an insurmountable inverse agonist, KW-6356. | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Adenosine receptor A2a,Soluble cytochrome b562, ... | | 著者 | Suzuki, M, Saito, J, Miyagi, H, Yasunaga, M. | | 登録日 | 2022-08-23 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | In Vitro Pharmacological Profile of KW-6356, a Novel Adenosine A 2A Receptor Antagonist/Inverse Agonist.
Mol.Pharmacol., 103, 2023
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8GNG
 | | Crystal structure of human adenosine A2A receptor in complex with istradefylline. | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 8-[(~{E})-2-(3,4-dimethoxyphenyl)ethenyl]-1,3-diethyl-7-methyl-purine-2,6-dione, Adenosine receptor A2a, ... | | 著者 | Suzuki, M, Saito, J, Miyagi, H, Yasunaga, M. | | 登録日 | 2022-08-23 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | In Vitro Pharmacological Profile of KW-6356, a Novel Adenosine A 2A Receptor Antagonist/Inverse Agonist.
Mol.Pharmacol., 103, 2023
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8GUQ
 | | Cryo-EM structure of CB2-G protein complex | | 分子名称: | Cannabinoid receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Wu, L.J, Hua, T, Liu, Z.J, Li, X.T, Chang, H. | | 登録日 | 2022-09-13 | | 公開日 | 2023-05-10 | | 最終更新日 | 2023-09-27 | | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | | 主引用文献 | Structural basis of selective cannabinoid CB 2 receptor activation.
Nat Commun, 14, 2023
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8GUR
 | | Cryo-EM structure of CP-CB2-G protein complex | | 分子名称: | 2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenol, Cannabinoid receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Wu, L.J, Hua, T, Liu, Z.J, Li, X.T, Chang, H. | | 登録日 | 2022-09-13 | | 公開日 | 2023-05-10 | | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | | 主引用文献 | Structural basis of selective cannabinoid CB 2 receptor activation.
Nat Commun, 14, 2023
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8GUS
 | | Cryo-EM structure of HU-CB2-G protein complex | | 分子名称: | Cannabinoid receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Wu, L.J, Hua, T, Liu, Z.J, Li, X.T, Chang, H. | | 登録日 | 2022-09-13 | | 公開日 | 2023-05-10 | | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | | 主引用文献 | Structural basis of selective cannabinoid CB 2 receptor activation.
Nat Commun, 14, 2023
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