8GUS

Cryo-EM structure of HU-CB2-G protein complex

Summary for 8GUS

• Entry DOI: 10.2210/pdb8gus/pdb
• EMDB information: 34278
• Descriptor: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• Functional Keywords: gpcr, g protein, cryo-em, membrane protein, structural protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 153615.34

Authors

Wu, L.J.,Hua, T.,Liu, Z.J.,Li, X.T.,Chang, H. (deposition date: 2022-09-13, release date: 2023-05-10)

• Primary citation: Li, X.,Chang, H.,Bouma, J.,de Paus, L.V.,Mukhopadhyay, P.,Paloczi, J.,Mustafa, M.,van der Horst, C.,Kumar, S.S.,Wu, L.,Yu, Y.,van den Berg, R.J.B.H.N.,Janssen, A.P.A.,Lichtman, A.,Liu, Z.J.,Pacher, P.,van der Stelt, M.,Heitman, L.H.,Hua, T.; Structural basis of selective cannabinoid CB 2 receptor activation.; Nat Commun, 14:1447-1447, 2023; PubMed: 36922494; DOI: 10.1038/s41467-023-37112-9

Experimental method

ELECTRON MICROSCOPY (2.97 Å)