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8GUS

Cryo-EM structure of HU-CB2-G protein complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Guanine nucleotide-binding protein G(i) subunit alpha-1polymer35440415.01UniProt (P63096)
Pfam (PF00503)
Homo sapiens (human)Adenylate cyclase-inhibiting G alpha protein
2B
(B)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1polymer34037416.91UniProt (P62873)
Pfam (PF00400)
Homo sapiens (human)Transducin beta chain 1,G protein beta subunit
3C
(C)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2polymer717861.11UniProt (P59768)
Pfam (PF00631)
Homo sapiens (human)G gamma-I,G protein gamma subunit
4D
(R)
Cannabinoid receptor 2polymer36039722.71UniProt (P34972)
Pfam (PF00001)
Homo sapiens (human)hCB2,CX5
5E
(S)
scFv16polymer25927784.91Homo sapiens
6F
(R)
[(1~{S},4~{S},5~{S})-4-[2,6-dimethoxy-4-(2-methyloctan-2-yl)phenyl]-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methanolnon-polymer414.61Chemie (KO3)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight153200.7
Non-Polymers*Number of molecules1
Total formula weight414.6
All*Total formula weight153615.3
*Water molecules are not included.

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PDB entries from 2025-05-21

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