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8GUS

Cryo-EM structure of HU-CB2-G protein complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Guanine nucleotide-binding protein G(i) subunit alpha-1polymer35440415.01UniProt (P63096)
Pfam (PF00503)
Homo sapiens (human)Adenylate cyclase-inhibiting G alpha protein
2B
(B)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1polymer34037416.91UniProt (P62873)
Pfam (PF25391)
Homo sapiens (human)Transducin beta chain 1,G protein beta subunit
3C
(C)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2polymer717861.11UniProt (P59768)
Pfam (PF00631)
Homo sapiens (human)G gamma-I,G protein gamma subunit
4D
(R)
Cannabinoid receptor 2polymer36039722.71UniProt (P34972)
Pfam (PF00001)
Homo sapiens (human)hCB2,CX5
5E
(S)
scFv16polymer25927784.91Homo sapiens
6F
(R)
[(1~{S},4~{S},5~{S})-4-[2,6-dimethoxy-4-(2-methyloctan-2-yl)phenyl]-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methanolnon-polymer414.61Chemie (KO3)
PubChem (5311172)
PubChem (9844711)
PubChem (9909745)
PubChem (11553430)
PubChem (20764337)
PubChem (23654859)
PubChem (38988321)
PubChem (57464684)
PubChem (57802194)
PubChem (51028412)
PubChem (59386636)
PubChem (59990116)
PubChem (60167548)
PubChem (70285091)
PubChem (71197165)
PubChem (71469098)
PubChem (101014676)
PubChem (57951695)
PubChem (70846994)
PubChem (70949667)
PubChem (70974211)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight153200.7
Non-Polymers*Number of molecules1
Total formula weight414.6
All*Total formula weight153615.3
*Water molecules are not included.

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PDB entries from 2026-03-25

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