PDB: 10970 件ウェブページステータス検索Chemie searchBIRD

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6N43	Crystal structure of cysteine, nitric oxide-bound ferrous form of the crosslinked human cysteine dioxygenase in the anaerobic condition 分子名称: CYSTEINE, Cysteine dioxygenase type 1, FE (III) ION, ... 著者 Liu, A, Li, J. 登録日 2018-11-16 公開日 2019-04-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.289 Å) 主引用文献 Probing the Cys-Tyr Cofactor Biogenesis in Cysteine Dioxygenase by the Genetic Incorporation of Fluorotyrosine. Biochemistry, 58, 2019
6MOE	Monomeric DARPin E2 complex with EpoR 分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, E2 DARPin, ... 著者 Jude, K.M, Mohan, K, Garcia, K.C. 登録日 2018-10-04 公開日 2019-06-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.091 Å) 主引用文献 Topological control of cytokine receptor signaling induces differential effects in hematopoiesis. Science, 364, 2019
6CA4	Crystal structure of humanized D. rerio TDP2 by 14 mutations 分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, MALONATE ION, ... 著者 Shi, K, Aihrara, H. 登録日 2018-01-29 公開日 2018-05-02 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.623 Å) 主引用文献 New fluorescence-based high-throughput screening assay for small molecule inhibitors of tyrosyl-DNA phosphodiesterase 2 (TDP2). Eur J Pharm Sci, 118, 2018
5MY9	Crystal structure of human 14-3-3 sigma in complex with LRRK2 peptide pS935 分子名称: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ... 著者 Stevers, L.M, de Vries, R.M.J.M, Ottmann, C. 登録日 2017-01-26 公開日 2017-03-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.327 Å) 主引用文献 Structural interface between LRRK2 and 14-3-3 protein. Biochem. J., 474, 2017
5MX0	Crystal structure of human fibromodulin 分子名称: CHLORIDE ION, Fibromodulin, NICKEL (II) ION, ... 著者 Paracuellos, P, Hohenester, E. 登録日 2017-01-20 公開日 2017-03-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Structural and functional analysis of two small leucine-rich repeat proteoglycans, fibromodulin and chondroadherin. Matrix Biol., 63, 2017
5CJP	The Structural Basis for Cdc42-Induced Dimerization of IQGAPs 分子名称: Cell division cycle 42 (GTP binding protein, 25kDa), isoform CRA_a, ... 著者 Worthylake, D.K, Boyapati, V.K, LeCour Jr, L. 登録日 2015-07-14 公開日 2016-08-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The Structural Basis for Cdc42-Induced Dimerization of IQGAPs. Structure, 24, 2016
6N4Q	CryoEM structure of Nav1.7 VSD2 (actived state) in complex with the gating modifier toxin ProTx2 分子名称: Beta/omega-theraphotoxin-Tp2a, Fab heavy chain, Fab light chain, ... 著者 Xu, H, Rohou, A, Arthur, C.P, Estevez, A, Ciferri, C, Payandeh, J, Koth, C.M. 登録日 2018-11-20 公開日 2019-01-23 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin. Cell, 176, 2019
3KEC	Crystal Structure of Human MMP-13 complexed with a phenyl-2H-tetrazole compound 分子名称: 4-{[({3-[2-(4-methoxybenzyl)-2H-tetrazol-5-yl]phenyl}carbonyl)amino]methyl}benzoic acid, ACETOHYDROXAMIC ACID, CALCIUM ION, ... 著者 Shieh, H.-S, Pavlovsky, A.G, Collins, B, Schnute, M.E. 登録日 2009-10-25 公開日 2010-11-10 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis. Bioorg.Med.Chem.Lett., 20, 2010
6FHG	Crystal structure of the Ts2631 endolysin from Thermus scotoductus phage with the unique N-terminal moiety responsible for peptidoglycan anchoring 分子名称: LysT endolysin, ZINC ION 著者 Zeth, K, Sancho-Vaello, E, Plotka, M. 登録日 2018-01-14 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure and function of the Ts2631 endolysin of Thermus scotoductus phage vB_Tsc2631 with unique N-terminal extension used for peptidoglycan binding. Sci Rep, 9, 2019
5C1C	Crystal Structure of the Pectin Methylesterase from Aspergillus niger in Deglycosylated Form 分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ... 著者 Jameson, G.B, Williams, M.A.K, Loo, T.S, Kent, L.M, Melton, L.D, Mercadante, D. 登録日 2015-06-13 公開日 2015-07-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure and Properties of a Non-processive, Salt-requiring, and Acidophilic Pectin Methylesterase from Aspergillus niger Provide Insights into the Key Determinants of Processivity Control. J.Biol.Chem., 291, 2016
6MOL	Monoextended DARPin M_R12 complex with EpoR 分子名称: Erythropoietin receptor, GLYCEROL, Monoextended DARPin R12 (M_R12) 著者 Jude, K.M, Mohan, K, Garcia, K.C, Guo, Y. 登録日 2018-10-04 公開日 2019-06-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.163 Å) 主引用文献 Topological control of cytokine receptor signaling induces differential effects in hematopoiesis. Science, 364, 2019
6MQI	Crystal Structure of the All-trans Retinal bound R111K:Y134F:T54V:R132Q:P39Y:R59Y:L121Q mutant of Human Cellular Retinoic Acid Binding Protein II Irradiated with 400 nm Laser for 5 minutes at 1.87 Angstrom Resolution 分子名称: Cellular retinoic acid-binding protein 2, RETINAL 著者 Ghanbarpour, A, Geiger, J. 登録日 2018-10-09 公開日 2019-01-09 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Mimicking Microbial Rhodopsin Isomerization in a Single Crystal. J. Am. Chem. Soc., 141, 2019
6CO4	Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets 分子名称: 26S proteasome non-ATPase regulatory subunit 1, Proteasomal ubiquitin receptor ADRM1 著者 Lu, X, Walters, K.J. 登録日 2018-03-11 公開日 2018-04-04 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets. Nat Commun, 8, 2017
6MQZ	Crystal Structure of the 13-cis Product of the All-trans Retinal-Bound R111K:Y134F:T54V:R132Q:P39Y:R59Y:L121E Mutant of Human Cellular Retinoic Acid Binding Protein II Irradiated with 400 nm Laser (5 minutes) at 2.07 Angstrom 分子名称: Cellular retinoic acid-binding protein 2, GLYCEROL, RETINAL 著者 Ghanbarpour, A, Geiger, J. 登録日 2018-10-11 公開日 2019-01-09 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Mimicking Microbial Rhodopsin Isomerization in a Single Crystal. J. Am. Chem. Soc., 141, 2019
5CBA	3B4 in complex with CXCL13 - 3B4-CXCL13 分子名称: 1,2-ETHANEDIOL, 3b4 heavy chain, 3b4 light chain, ... 著者 Tu, C, Bard, J, Mosyak, L. 登録日 2015-06-30 公開日 2015-11-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A Combination of Structural and Empirical Analyses Delineates the Key Contacts Mediating Stability and Affinity Increases in an Optimized Biotherapeutic Single-chain Fv (scFv). J. Biol. Chem., 291, 2016
6MQX	Crystal Structure of All-trans Retinal-Bound R111K:Y134F:T54V:R132Q:P39Y:R59Y:L121E Human Cellular Retinoic Acid Binding Protein II Irradiated with 400 nm Laser (30 seconds) and Subsequently Dark Adapted (25 minutes) at 2.0 Angstrom Resolution 分子名称: Cellular retinoic acid-binding protein 2, GLYCEROL, RETINAL 著者 Ghanbarpour, A, Geiger, J. 登録日 2018-10-11 公開日 2019-01-09 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Mimicking Microbial Rhodopsin Isomerization in a Single Crystal. J. Am. Chem. Soc., 141, 2019
6F8H	antitoxin GraA 分子名称: XRE family transcriptional regulator 著者 Talavera, A, Loris, R. 登録日 2017-12-13 公開日 2019-01-30 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.002 Å) 主引用文献 A dual role in regulation and toxicity for the disordered N-terminus of the toxin GraT. Nat Commun, 10, 2019
3KHP	Crystal structure of a possible dehydrogenase from Mycobacterium tuberculosis at 2.3A resolution 分子名称: CHLORIDE ION, L(+)-TARTARIC ACID, MaoC family protein 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2009-10-30 公開日 2009-12-01 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3KEK	Crystal Structure of Human MMP-13 complexed with a (pyridin-4-yl)-2H-tetrazole compound 分子名称: CALCIUM ION, Collagenase 3, ZINC ION, ... 著者 Shieh, H.-S, Collins, B, Schnute, M.E. 登録日 2009-10-26 公開日 2010-11-10 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis. Bioorg.Med.Chem.Lett., 20, 2009
6N42	Crystal structure of cysteine-bound ferrous form of the crosslinked human cysteine dioxygenase in the anaerobic condition 分子名称: CYSTEINE, Cysteine dioxygenase type 1, FE (II) ION, ... 著者 Liu, A, Li, J. 登録日 2018-11-16 公開日 2019-04-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.199 Å) 主引用文献 Probing the Cys-Tyr Cofactor Biogenesis in Cysteine Dioxygenase by the Genetic Incorporation of Fluorotyrosine. Biochemistry, 58, 2019
6BXT	Crystal structure of Toxoplasma gondii Mitochondrial Association Factor 1 A (MAF1A) in complex with ADPribose 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, mitochondrial association factor 1 著者 Parker, M.L, Ramaswamy, R, Boulanger, M.J. 登録日 2017-12-18 公開日 2018-12-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A Toxoplasma gondii locus required for the direct manipulation of host mitochondria has maintained multiple ancestral functions. Mol. Microbiol., 108, 2018
6FI2	VexL: A periplasmic depolymerase provides new insight into ABC transporter-dependent secretion of bacterial capsular polysaccharides 分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranuronic acid-(1-4)-3-O-acetyl-2-acetamido-2-deoxy-alpha-D-galactopyranuronic acid-(1-4)-3-O-acetyl-2-acetamido-2-deoxy-alpha-D-galactopyranuronic acid, MALONATE ION, VexL 著者 Naismith, J.H, McMahon, S.A, Le Bas, A, Liston, S.D, Whitfield, C. 登録日 2018-01-16 公開日 2018-05-02 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.22 Å) 主引用文献 Periplasmic depolymerase provides insight into ABC transporter-dependent secretion of bacterial capsular polysaccharides. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6CL0	Human caspase-3 in complex with Ac-ATS009-KE 分子名称: ACE-1MH-ASP-PF5-PHE-1U8, Caspase-3 subunit p12, Caspase-3 subunit p17 著者 Solania, A.T, Gonzalez-Paez, G.E, Wolan, D.W. 登録日 2018-03-01 公開日 2019-03-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Selective and Rapid Cell-Permeable Inhibitor of Human Caspase-3. Acs Chem.Biol., 14, 2019
6N2Y	Bacillus PS3 ATP synthase class 1 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... 著者 Guo, H, Rubinstein, J.L. 登録日 2018-11-14 公開日 2019-02-20 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structure of a bacterial ATP synthase. Elife, 8, 2019
6N4I	Structural basis of Nav1.7 inhibition by a gating-modifier spider toxin 分子名称: Beta/omega-theraphotoxin-Tp2a, Nav1.7 VSD2-NavAb channel chimera protein, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate 著者 Xu, H, Koth, C.M, Payandeh, J. 登録日 2018-11-19 公開日 2019-01-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.541 Å) 主引用文献 Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin. Cell, 176, 2019

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