8AC8
 
 | | The nucleoprotein complex of Rep protein with DUE ssDNA | | 分子名称: | DNA (5'-D(*AP*TP*TP*TP*TP*TP*AP*TP*A)-3'), Replication initiation protein | | 著者 | Nowacka, M, Wegrzyn, K, Oliwa, M, Konieczny, I. | | 登録日 | 2022-07-05 | | 公開日 | 2023-09-27 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Rep protein accommodates together dsDNA and ssDNA which enables a loop-back mechanism to plasmid DNA replication initiation.
Nucleic Acids Res., 51, 2023
|
|
3N06
 | | A mutant human Prolactin receptor antagonist H27A in complex with the extracellular domain of the human prolactin receptor | | 分子名称: | CHLORIDE ION, Prolactin, Prolactin receptor, ... | | 著者 | Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E. | | 登録日 | 2010-05-13 | | 公開日 | 2010-09-29 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation.
J.Biol.Chem., 285, 2010
|
|
8JAY
 | | CrtSPARTA Octamer bound with guide-target | | 分子名称: | DNA (25-MER), MAGNESIUM ION, Piwi domain-containing protein, ... | | 著者 | Guo, L.J, Huang, P.P, Li, Z.X, Xiao, Y.B, Chen, M.R. | | 登録日 | 2023-05-07 | | 公開日 | 2024-03-20 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system.
Nat.Chem.Biol., 20, 2024
|
|
6NXX
 | | Crystal structure of Arabidopsis thaliana cytosolic triosephosphate isomerase C218K mutant | | 分子名称: | SODIUM ION, Triosephosphate isomerase, cytosolic | | 著者 | Jimenez-Sandoval, P, Fuentes-Pascacio, A, Diaz-Quezada, C, Torres-Larios, A, Brieba, L.G. | | 登録日 | 2019-02-10 | | 公開日 | 2020-02-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Structural basis for the modulation of plant cytosolic triosephosphate isomerase activity by mimicry of redox-based modifications.
Plant J., 99, 2019
|
|
4J0B
 | | Structure of mitochondrial Hsp90 (TRAP1) with ADP-BeF3 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, COBALT (II) ION, ... | | 著者 | Partridge, J.R, Lavery, L.A, Agard, D.A. | | 登録日 | 2013-01-30 | | 公開日 | 2014-01-22 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.352 Å) | | 主引用文献 | Structural asymmetry in the closed state of mitochondrial Hsp90 (TRAP1) supports a two-step ATP hydrolysis mechanism.
Mol.Cell, 53, 2014
|
|
7UD6
 | |
6CQ8
 | | K2P2.1(TREK-1):ML335 complex | | 分子名称: | CADMIUM ION, HEXADECANE, N-((E,2S,3R)-1,3-DIHYDROXYOCTADEC-4-EN-2-YL)PALMITAMIDE, ... | | 著者 | Lolicato, M, Minor, D.L. | | 登録日 | 2018-03-14 | | 公開日 | 2018-03-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site.
Nature, 547, 2017
|
|
6CQD
 | | Crystal structure of HPK1 in complex with ATP analogue (AMPPNP) | | 分子名称: | MAGNESIUM ION, Mitogen-activated protein kinase kinase kinase kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | 著者 | Wu, P, Lehoux, I, Franke, Y, Mortara, K, Wang, W. | | 登録日 | 2018-03-14 | | 公開日 | 2018-12-19 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Hematopoietic Progenitor Kinase-1 Structure in a Domain-Swapped Dimer.
Structure, 27, 2019
|
|
3NQJ
 | |
8JES
 | | Cryo-EM structure of DltB homo-tetramer | | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, DIACYL GLYCEROL, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Zhang, P, Liu, Z. | | 登録日 | 2023-05-16 | | 公開日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | | 主引用文献 | Structural insights into the transporting and catalyzing mechanism of DltB in LTA D-alanylation.
Nat Commun, 15, 2024
|
|
8JF2
 | | Cryo-EM structure of tetrameric DltB/DltC complex | | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, D-alanyl carrier protein, DIACYL GLYCEROL, ... | | 著者 | Zhang, P, Liu, Z. | | 登録日 | 2023-05-17 | | 公開日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural insights into the transporting and catalyzing mechanism of DltB in LTA D-alanylation.
Nat Commun, 15, 2024
|
|
4IVG
 | | Crystal structure of mitochondrial Hsp90 (TRAP1) NTD-Middle domain dimer with AMPPNP | | 分子名称: | MAGNESIUM ION, PHOSPHATE ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Partridge, J.R, Lavery, L.A, Agard, D.A. | | 登録日 | 2013-01-22 | | 公開日 | 2014-01-22 | | 最終更新日 | 2014-08-27 | | 実験手法 | X-RAY DIFFRACTION (1.749 Å) | | 主引用文献 | Structural asymmetry in the closed state of mitochondrial Hsp90 (TRAP1) supports a two-step ATP hydrolysis mechanism.
Mol.Cell, 53, 2014
|
|
6BJ8
 | | TCR55 in complex with Pep20/HLA-B35 | | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | | 著者 | Jude, K.M, Sibener, L.V, Yang, X, Garcia, K.C. | | 登録日 | 2017-11-05 | | 公開日 | 2018-07-25 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding.
Cell, 174, 2018
|
|
6NXQ
 | | Crystal structure of Arabidopsis thaliana cytosolic triosephosphate isomerase C13A mutant | | 分子名称: | SODIUM ION, Triosephosphate isomerase, cytosolic | | 著者 | Jimenez-Sandoval, P, Diaz-Quezada, C, Torres-Larios, A, Brieba, L.G. | | 登録日 | 2019-02-09 | | 公開日 | 2020-02-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Structural basis for the modulation of plant cytosolic triosephosphate isomerase activity by mimicry of redox-based modifications.
Plant J., 99, 2019
|
|
8JEM
 | | DltB tetramer in complex with inhibitor m-AMSA | | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, DIACYL GLYCEROL, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Zhang, P, Liu, Z. | | 登録日 | 2023-05-16 | | 公開日 | 2024-05-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | | 主引用文献 | Structural insights into the transporting and catalyzing mechanism of DltB in LTA D-alanylation.
Nat Commun, 15, 2024
|
|
6NXW
 | | Crystal structure of Arabidopsis thaliana cytosolic triosephosphate isomerase C218S mutant | | 分子名称: | Triosephosphate isomerase, cytosolic | | 著者 | Jimenez-Sandoval, P, Diaz-Quezada, C, Torres-Larios, A, Brieba, L.G. | | 登録日 | 2019-02-10 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural basis for the modulation of plant cytosolic triosephosphate isomerase activity by mimicry of redox-based modifications.
Plant J., 99, 2019
|
|
6NXR
 | | Crystal structure of Arabidopsis thaliana cytosolic triosephosphate isomerase C13D mutant | | 分子名称: | GLYCEROL, SODIUM ION, Triosephosphate isomerase, ... | | 著者 | Jimenez-Sandoval, P, Diaz-Quezada, C, Torres-Larios, A, Brieba, L.G. | | 登録日 | 2019-02-09 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structural basis for the modulation of plant cytosolic triosephosphate isomerase activity by mimicry of redox-based modifications.
Plant J., 99, 2019
|
|
6NXY
 | | Crystal structure of Arabidopsis thaliana cytosolic triosephosphate isomerase C218D mutant | | 分子名称: | SODIUM ION, Triosephosphate isomerase, cytosolic | | 著者 | Jimenez-Sandoval, P, Diaz-Quezada, C, Torres-Larios, A, Brieba, L.G. | | 登録日 | 2019-02-10 | | 公開日 | 2020-02-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Structural basis for the modulation of plant cytosolic triosephosphate isomerase activity by mimicry of redox-based modifications.
Plant J., 99, 2019
|
|
5JVK
 | | Structural insights into a family 39 glycoside hydrolase from the gut symbiont Bacteroides cellulosilyticus WH2. | | 分子名称: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, GLYCEROL, SULFATE ION, ... | | 著者 | Ali-Ahmad, A, Garron, M.L, Zamboni, V, Lenfant, N, Bourne, Y, Vincent, F. | | 登録日 | 2016-05-11 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural insights into a family 39 glycoside hydrolase from the gut symbiont Bacteroides cellulosilyticus WH2.
J. Struct. Biol., 197, 2017
|
|
6BVZ
 | | Importin alpha 3 in cargo free state | | 分子名称: | Importin subunit alpha-3 | | 著者 | Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. | | 登録日 | 2017-12-14 | | 公開日 | 2018-07-04 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
|
|
6CQE
 | | Crystal structure of HPK1 kinase domain S171A mutant | | 分子名称: | Mitogen-activated protein kinase kinase kinase kinase 1 | | 著者 | Wu, P, Lehoux, I, Mortara, K, Franke, Y, Wang, W. | | 登録日 | 2018-03-15 | | 公開日 | 2018-12-19 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.886 Å) | | 主引用文献 | Hematopoietic Progenitor Kinase-1 Structure in a Domain-Swapped Dimer.
Structure, 27, 2019
|
|
8BVB
 | |
4IYN
 | | Structure of mitochondrial Hsp90 (TRAP1) with ADP-ALF4- | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, COBALT (II) ION, MAGNESIUM ION, ... | | 著者 | Partridge, J.R, Lavery, L.A, Agard, D.A. | | 登録日 | 2013-01-28 | | 公開日 | 2014-01-22 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.312 Å) | | 主引用文献 | Structural asymmetry in the closed state of mitochondrial Hsp90 (TRAP1) supports a two-step ATP hydrolysis mechanism.
Mol.Cell, 53, 2014
|
|
2AZY
 | | Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with Cholate | | 分子名称: | CALCIUM ION, CHOLIC ACID, Phospholipase A2, ... | | 著者 | Pan, Y.H, Bahnson, B.J, Jain, M.K. | | 登録日 | 2005-09-12 | | 公開日 | 2006-11-14 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural basis for bile salt inhibition of pancreatic phospholipase A2.
J.Mol.Biol., 369, 2007
|
|
7W80
 | | Crystal Structure of the Heterodimeric HIF-2 in Complex with Antagonist Belzutifan | | 分子名称: | 3-{[(1S,2S,3R)-2,3-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl]oxy}-5-fluorobenzonitrile, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1 | | 著者 | Ren, X, Diao, X, Zhuang, J, Wu, D. | | 登録日 | 2021-12-07 | | 公開日 | 2022-09-21 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.754 Å) | | 主引用文献 | Structural basis for the allosteric inhibition of hypoxia-inducible factor (HIF)-2 by belzutifan.
Mol.Pharmacol., 2022
|
|
