6FSM
| Crystal structure of TCE-treated Thermolysin | 分子名称: | CALCIUM ION, GLYCEROL, LYSINE, ... | 著者 | Pichlo, C, Baumann, U. | 登録日 | 2018-02-19 | 公開日 | 2018-05-02 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | 主引用文献 | Improved protein-crystal identification by using 2,2,2-trichloroethanol as a fluorescence enhancer. Acta Crystallogr F Struct Biol Commun, 74, 2018
|
|
1U5V
| Structure of CitE complexed with triphosphate group of ATP form Mycobacterium tuberculosis | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, FORMIC ACID, citE | 著者 | Goulding, C.W, Lerkin, T, Kim, C.Y, Segelke, B, Terwilliger, T, Eisenberg, E, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2004-07-28 | 公開日 | 2004-10-12 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure of Mycobacterium tuberculosis citrate lyase beta subunit and its unusual triphosphate binding site To be Published
|
|
1UAG
| |
1U65
| Ache W. CPT-11 | 分子名称: | (4S)-4,11-DIETHYL-4-HYDROXY-3,14-DIOXO-3,4,12,14-TETRAHYDRO-1H-PYRANO[3',4':6,7]INDOLIZINO[1,2-B]QUINOLIN-9-YL 1,4'-BIPIPERIDINE-1'-CARBOXYLATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, ... | 著者 | Harel, M, Hyatt, J.L, Brumshtein, B, Morton, C.L, Wadkins, R.W, Silman, I, Sussman, J.L, Potter, P.M, Israel Structural Proteomics Center (ISPC) | 登録日 | 2004-07-29 | 公開日 | 2005-07-19 | 最終更新日 | 2021-06-02 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | The crystal structure of the complex of the anticancer prodrug 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin (CPT-11) with Torpedo californica acetylcholinesterase provides a molecular explanation for its cholinergic action Mol.Pharmacol., 67, 2005
|
|
3ZGI
| Crystal structure of the KRT10-binding region domain of the pneumococcal serine rich repeat protein PsrP | 分子名称: | 1,2-ETHANEDIOL, CELL WALL SURFACE ANCHOR FAMILY PROTEIN, SULFATE ION | 著者 | Schulte, T, Loefling, J, Mikaelsson, C, Kikhney, A, Hentrich, K, Diamante, A, Ebel, C, Normark, S, Svergun, D, Henriques-Normark, B, Achour, A. | 登録日 | 2012-12-17 | 公開日 | 2013-12-25 | 最終更新日 | 2019-05-08 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | The Basic Keratin 10-Binding Domain of the Virulence-Associated Pneumococcal Serine-Rich Protein Psrp Adopts a Novel Mscramm Fold. Open Biol., 4, 2014
|
|
6G2H
| Filament of acetyl-CoA carboxylase and BRCT domains of BRCA1 (ACC-BRCT) core at 4.6 A resolution | 分子名称: | Acetyl-CoA carboxylase 1 | 著者 | Hunkeler, M, Hagmann, A, Stuttfeld, E, Chami, M, Stahlberg, H, Maier, T. | 登録日 | 2018-03-23 | 公開日 | 2018-06-13 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Structural basis for regulation of human acetyl-CoA carboxylase. Nature, 558, 2018
|
|
1TZS
| Crystal Structure of an activation intermediate of Cathepsin E | 分子名称: | 23-mer peptide from PelB-IgG kappa light chain fusion protein, Cathepsin E, activation peptide from Cathepsin E | 著者 | Ostermann, N, Gerhartz, B, Worpenberg, S, Trappe, J, Eder, J. | 登録日 | 2004-07-12 | 公開日 | 2005-07-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Crystal structure of an activation intermediate of cathepsin e J.Mol.Biol., 342, 2004
|
|
6FOM
| Copper transporter OprC | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Putative copper transport outer membrane porin OprC | 著者 | Bhamidimarri, S.P, van den Berg, B. | 登録日 | 2018-02-07 | 公開日 | 2019-03-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Acquisition of ionic copper by the bacterial outer membrane protein OprC through a novel binding site. Plos Biol., 19, 2021
|
|
3X1O
| Crystal structure of the ROQ domain of human Roquin | 分子名称: | IODIDE ION, Roquin-1 | 著者 | Ose, T, Verma, A, Cockburn, J.B, Berrow, N.S, Alderton, D, Stuart, D, Owens, R.J, Jones, E.Y. | 登録日 | 2014-11-26 | 公開日 | 2015-03-11 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | 主引用文献 | Roquin binds microRNA-146a and Argonaute2 to regulate microRNA homeostasis Nat Commun, 6, 2015
|
|
3NAE
| RB69 DNA Polymerase (Y567A) Ternary Complex with dATP Opposite Guanidinohydantoin | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... | 著者 | Wang, M, Beckman, J, Blaha, G, Wang, J, Konigsberg, W.H. | 登録日 | 2010-06-01 | 公開日 | 2010-09-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.003 Å) | 主引用文献 | Substitution of Ala for Tyr567 in RB69 DNA Polymerase Allows dAMP and dGMP To Be Inserted opposite Guanidinohydantoin . Biochemistry, 49, 2010
|
|
3P50
| Structure of propofol bound to a pentameric ligand-gated ion channel, GLIC | 分子名称: | 2,6-BIS(1-METHYLETHYL)PHENOL, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ... | 著者 | Nury, H, Van Renterghem, C, Weng, Y, Tran, A, Baaden, M, Dufresne, V, Changeux, J.P, Sonner, J.M, Delarue, M, Corringer, P.J. | 登録日 | 2010-10-07 | 公開日 | 2011-01-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel Nature, 469, 2011
|
|
1RK4
| Crystal Structure of a Soluble Dimeric Form of Oxidised CLIC1 | 分子名称: | CHLORIDE INTRACELLULAR CHANNEL PROTEIN 1 | 著者 | Littler, D.R, Harrop, S.J, Fairlie, W.D, Brown, L.J, Pankhurst, G.J, Pankhurst, S, DeMaere, M.Z, Campbell, T.J, Bauskin, A.R, Tonini, R, Mazzanti, M, Breit, S.N, Curmi, P.M. | 登録日 | 2003-11-20 | 公開日 | 2003-12-02 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.792 Å) | 主引用文献 | The Intracellular Chloride Ion Channel Protein CLIC1 Undergoes a Redox-controlled Structural Transition J.Biol.Chem., 279, 2004
|
|
3P4W
| Structure of desflurane bound to a pentameric ligand-gated ion channel, GLIC | 分子名称: | (2S)-2-(difluoromethoxy)-1,1,1,2-tetrafluoroethane, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ... | 著者 | Nury, H, Van Renterghem, C, Weng, Y, Tran, A, Baaden, M, Dufresne, V, Changeux, J.P, Sonner, J.M, Delarue, M, Corringer, P.J. | 登録日 | 2010-10-07 | 公開日 | 2011-01-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel Nature, 469, 2011
|
|
6G1Q
| ADP-ribosylserine hydrolase ARH3 of Latimeria chalumnae in complex with ADP-ribose | 分子名称: | ADP-ribosylhydrolase like 2, MAGNESIUM ION, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | 著者 | Ariza, A. | 登録日 | 2018-03-21 | 公開日 | 2018-11-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | (ADP-ribosyl)hydrolases: Structural Basis for Differential Substrate Recognition and Inhibition. Cell Chem Biol, 25, 2018
|
|
7K16
| Tamana Bat Virus xrRNA1 | 分子名称: | MAGNESIUM ION, RNA (51-MER), SODIUM ION | 著者 | Jones, R.A, Kieft, J.S. | 登録日 | 2020-09-07 | 公開日 | 2020-10-14 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Different tertiary interactions create the same important 3D features in a distinct flavivirus xrRNA. Rna, 27, 2021
|
|
1R6G
| Crystal structure of the thyroid hormone receptor beta ligand binding domain in complex with a beta selective compound | 分子名称: | 2-[3,5-DIBROMO-4-(4-HYDROXY-3-{HYDROXY[(2-PHENYLETHYL)AMINO]METHYL}PHENOXY)PHENYL]ETHANE-1,1-DIOL, Thyroid hormone receptor beta-1 | 著者 | Hangeland, J.J, Dejneka, T, Friends, T.J, Devasthale, P, Mellstrom, K, Sandberg, J, Grynfarb, M, Doweyko, A.M, Sack, J.S, Einspahr, H, Farnegardh, M, Husman, B, Ljunggren, J, Koehler, K, Sheppard, C, Malm, J, Ryono, D.E. | 登録日 | 2003-10-15 | 公開日 | 2005-02-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Thyroid receptor ligands. Part 2: Thyromimetics with improved selectivity for the thyroid hormone receptor beta. Bioorg.Med.Chem.Lett., 14, 2004
|
|
3OX0
| |
1R2W
| Coordinates of L11 with 58nts of 23S rRNA fitted into the cryo-EM map of the 70S ribosome | 分子名称: | 50S ribosomal protein L11, 58nts of 23S rRNA | 著者 | Valle, M, Zavialov, A, Li, W, Stagg, S.M, Sengupta, J, Nielsen, R.C, Nissen, P, Harvey, S.C, Ehrenberg, M, Frank, J. | 登録日 | 2003-09-30 | 公開日 | 2003-11-04 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (9 Å) | 主引用文献 | Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron Microscopy Nat.Struct.Biol., 10, 2003
|
|
6FXX
| Crystal Structure of full-length Human Lysyl Hydroxylase LH3 - Cocrystal with Fe2+, Mn2+, UDP-Gal, Hg2+ Soak | 分子名称: | 2-OXOGLUTARIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Scietti, L, Chiapparino, A, De Giorgi, F, Fumagalli, M, Khoriauli, L, Nergadze, S, Basu, S, Olieric, V, Banushi, B, Giulotto, E, Gissen, P, Forneris, F. | 登録日 | 2018-03-09 | 公開日 | 2018-08-22 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3. Nat Commun, 9, 2018
|
|
7LH6
| |
6FVF
| The Structure of CK2alpha with CCh503 bound | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Casein kinase II subunit alpha, [1-[2-(phenylsulfonylamino)ethyl]piperidin-4-yl]methyl 5-fluoranyl-2-methoxy-1~{H}-indole-3-carboxylate | 著者 | Brear, P, Prudent, R, Laudet, B, Filhol, O, Cochet, C, Sautel, C, Moucadel, V, Bestgen, B, Engel, M, Ettaoussi, M, Lomberget, T, Le Borgne, M, Kufareva, I, Abagyan, R, Hyvonen, M. | 登録日 | 2018-03-02 | 公開日 | 2019-06-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Discovery of holoenzyme-disrupting chemicals as substrate-selective CK2 inhibitors. Sci Rep, 9, 2019
|
|
6QCY
| MloK1 model from single particle analysis of 2D crystals, class 2 (intermediate conformation) | 分子名称: | Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION | 著者 | Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H. | 登録日 | 2018-12-31 | 公開日 | 2019-04-24 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM. Nat Commun, 10, 2019
|
|
1RH5
| The structure of a protein conducting channel | 分子名称: | Preprotein translocase secE subunit, Preprotein translocase secY subunit, SecBeta | 著者 | van den Berg, B, Clemons Jr, W.M, Collinson, I, Modis, Y, Hartmann, E, Harrison, S.C, Rapoport, T.A. | 登録日 | 2003-11-13 | 公開日 | 2004-01-06 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | X-ray structure of a protein-conducting channel Nature, 427, 2004
|
|
7LHA
| |
6G2D
| Citrate-induced acetyl-CoA carboxylase (ACC-Cit) filament at 5.4 A resolution | 分子名称: | Acetyl-CoA carboxylase 1 | 著者 | Hunkeler, M, Hagmann, A, Stuttfeld, E, Chami, M, Stahlberg, H, Maier, T. | 登録日 | 2018-03-23 | 公開日 | 2018-06-13 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (5.4 Å) | 主引用文献 | Structural basis for regulation of human acetyl-CoA carboxylase. Nature, 558, 2018
|
|