1RK4

Crystal Structure of a Soluble Dimeric Form of Oxidised CLIC1

Summary for 1RK4

Related1K0M
DescriptorCHLORIDE INTRACELLULAR CHANNEL PROTEIN 1 (2 entities in total)
Functional Keywordsglutathione-s-tranferase superfamily; chloride ion channel; redox-controlled structural transition, ion transport-membrane protein complex, ion transport/membrane protein
Biological sourceHomo sapiens (human)
Cellular locationNucleus O00299
Total number of polymer chains2
Total molecular weight54193.63
Authors
Primary citation
Littler, D.R.,Harrop, S.J.,Fairlie, W.D.,Brown, L.J.,Pankhurst, G.J.,Pankhurst, S.,DeMaere, M.Z.,Campbell, T.J.,Bauskin, A.R.,Tonini, R.,Mazzanti, M.,Breit, S.N.,Curmi, P.M.
The Intracellular Chloride Ion Channel Protein CLIC1 Undergoes a Redox-controlled Structural Transition
J.Biol.Chem., 279:9298-9305, 2004
PubMed: 14613939 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M308444200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.792 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.22230 3.0% 6.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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168889
PDB entries from 2020-09-16