1RK4

Crystal Structure of a Soluble Dimeric Form of Oxidised CLIC1

Summary for 1RK4

• Entry DOI: 10.2210/pdb1rk4/pdb
• Related: 1K0M
• Descriptor: CHLORIDE INTRACELLULAR CHANNEL PROTEIN 1 (2 entities in total)
• Functional Keywords: glutathione-s-tranferase superfamily; chloride ion channel; redox-controlled structural transition, ion transport-membrane protein complex, ion transport/membrane protein
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: O00299
• Total number of polymer chains: 2
• Total formula weight: 54193.63

Authors

Littler, D.R.,Harrop, S.J.,Fairlie, W.D.,Brown, L.J.,Pankhurst, G.J.,Pankhurst, S.,DeMaere, M.Z.,Campbell, T.J.,Bauskin, A.R.,Tonini, R.,Mazzanti, M.,Breit, S.N.,Curmi, P.M. (deposition date: 2003-11-20, release date: 2003-12-02, Last modification date: 2023-08-23)

• Primary citation: Littler, D.R.,Harrop, S.J.,Fairlie, W.D.,Brown, L.J.,Pankhurst, G.J.,Pankhurst, S.,DeMaere, M.Z.,Campbell, T.J.,Bauskin, A.R.,Tonini, R.,Mazzanti, M.,Breit, S.N.,Curmi, P.M.; The Intracellular Chloride Ion Channel Protein CLIC1 Undergoes a Redox-controlled Structural Transition; J.Biol.Chem., 279:9298-9305, 2004; PubMed: 14613939; DOI: 10.1074/jbc.M308444200

Experimental method

X-RAY DIFFRACTION (1.792 Å)