PDB: 184249 件ウェブページステータス検索Chemie searchBIRD

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8BNA	BINDING OF HOECHST 33258 TO THE MINOR GROOVE OF B-DNA 分子名称: 2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION 著者 Pjura, P.E, Grzeskowiak, K, Dickerson, R.E. 登録日 1986-08-29 公開日 1987-01-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Binding of Hoechst 33258 to the minor groove of B-DNA. J.Mol.Biol., 197, 1987
1HGE	BINDING OF INFLUENZA VIRUS HEMAGGLUTININ TO ANALOGS OF ITS CELL-SURFACE RECEPTOR, SIALIC ACID: ANALYSIS BY PROTON NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND X-RAY CRYSTALLOGRAPHY 分子名称: 2-O-methyl-5-N-acetyl-alpha-D-neuraminic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, ... 著者 Sauter, N.K, Hanson, J.E, Glick, G.D, Brown, J.H, Crowther, R.L, Park, S.-J, Skehel, J.J, Wiley, D.C. 登録日 1991-11-01 公開日 1994-01-31 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Binding of influenza virus hemagglutinin to analogs of its cell-surface receptor, sialic acid: analysis by proton nuclear magnetic resonance spectroscopy and X-ray crystallography. Biochemistry, 31, 1992
4X65	Crystal Structure of 30S ribosomal subunit from Thermus thermophilus 分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Demirci, H, Chen, J, Choi, J, Soltis, M, Puglisi, J.D. 登録日 2014-12-06 公開日 2015-11-18 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (3.345 Å) 主引用文献 N(6)-methyladenosine in mRNA disrupts tRNA selection and translation-elongation dynamics. Nat.Struct.Mol.Biol., 23, 2016
5WEW	Crystal structure of Klebsiella pneumoniae fosfomycin resistance protein (FosAKP) with inhibitor (ANY1) bound 分子名称: 6,6'-(4-nitro-1H-pyrazole-3,5-diyl)bis(3-bromopyrazolo[1,5-a]pyrimidin-2(1H)-one), Fosfomycin resistance protein, MANGANESE (II) ION 著者 Klontz, E.H, Sundberg, E.J. 登録日 2017-07-10 公開日 2018-07-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.178 Å) 主引用文献 Small-Molecule Inhibitor of FosA Expands Fosfomycin Activity to Multidrug-Resistant Gram-Negative Pathogens. Antimicrob. Agents Chemother., 63, 2019
1H48	The structure of 2C-Methyl-D-erythritol 2,4-cyclodiphosphate synthase in complex with CMP and product 分子名称: 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE, 2C-METHYL-D-ERYTHRITOL-2,4-CYCLODIPHOSPHATE SYNTHASE, CYTIDINE-5'-MONOPHOSPHATE, ... 著者 Kemp, L.E, Alphey, M.S, Bond, C.S, Hunter, W.N. 登録日 2003-02-24 公開日 2004-12-22 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The Identification of Isoprenoids that Bind in the Intersubunit Cavity of Escherichia Coli 2C-Methyl-D-Erythritol-2,4-Cyclodiphosphate Synthase by Complementary Biophysical Methods Acta Crystallogr.,Sect.D, 61, 2005
6QHZ	Time resolved structural analysis of the full turnover of an enzyme - 6788 ms 分子名称: Fluoroacetate dehalogenase, fluoroacetic acid 著者 Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D. 登録日 2019-01-17 公開日 2019-09-25 実験手法 X-RAY DIFFRACTION (1.799 Å) 主引用文献 Time-resolved crystallography reveals allosteric communication aligned with molecular breathing. Science, 365, 2019
7LRM	Structure of HIV-1 Reverse Transcriptase in complex with DNA, dCTP, and CA(2+) ion 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA/RNA (38-MER), ... 著者 Hoang, A, Ruiz, F.X, Arnold, E. 登録日 2021-02-16 公開日 2022-02-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.14 Å) 主引用文献 Structural basis of HIV inhibition by L-nucleosides: Opportunities for drug development and repurposing. Drug Discov Today, 27, 2022
8QTT	Crystal structure of a C-terminally truncated version of Arabidopsis thaliana 14-3-3 omega in complex with a phosphopeptide from the inhibitor protein BKI1. 分子名称: 1,2-ETHANEDIOL, 14-3-3-like protein GF14 omega, BRI1 kinase inhibitor 1, ... 著者 Hothorn, M, Obergfell, E. 登録日 2023-10-13 公開日 2023-11-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Mechanistic insights into the function of 14-3-3 proteins as negative regulators of brassinosteroid signaling in Arabidopsis. Plant Cell.Physiol., 2024
7LRY	Structure of HIV-1 Reverse Transcriptase in complex with DNA, (-)FTC-TP, and CA(2+) ion 分子名称: AMMONIUM ION, CALCIUM ION, DNA/RNA (38-MER), ... 著者 Hoang, A, Ruiz, F.X, Arnold, E. 登録日 2021-02-17 公開日 2022-02-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structural basis of HIV inhibition by L-nucleosides: Opportunities for drug development and repurposing. Drug Discov Today, 27, 2022
8QTF	Crystal structure of a C-terminally truncated version of Arabidopsis thaliana 14-3-3 omega in complex with a phosphopeptide from the transcription factor BZR1. 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 14-3-3-like protein GF14 omega, ... 著者 Hothorn, M, Obergfell, E. 登録日 2023-10-12 公開日 2023-11-22 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Mechanistic insights into the function of 14-3-3 proteins as negative regulators of brassinosteroid signaling in Arabidopsis. Plant Cell.Physiol., 2024
7LSK	Structure of HIV-1 Reverse Transcriptase in complex with DNA, L-dTTP, and CA(2+) ion 分子名称: 1-{2-deoxy-5-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-L-erythro-pentofuranosyl}-5-methylpyrimidine-2,4(1H,3H)-dione, AMMONIUM ION, CALCIUM ION, ... 著者 Hoang, A, Ruiz, F.X, Arnold, E. 登録日 2021-02-18 公開日 2022-02-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis of HIV inhibition by L-nucleosides: Opportunities for drug development and repurposing. Drug Discov Today, 27, 2022
7LRI	Structure of HIV-1 Reverse Transcriptase in complex with DNA, dTTP, and CA(2+) ion 分子名称: CALCIUM ION, DNA/RNA (38-MER), GLYCEROL, ... 著者 Hoang, A, Ruiz, F.X, Arnold, E. 登録日 2021-02-16 公開日 2022-02-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Structural basis of HIV inhibition by L-nucleosides: Opportunities for drug development and repurposing. Drug Discov Today, 27, 2022
7B8F	Notum-Fragment 154 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(benzimidazol-1-ylmethyl)benzenecarbonitrile, ... 著者 Zhao, Y, Jonees, E.Y. 登録日 2020-12-12 公開日 2022-01-12 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Structural Analysis and Development of Notum Fragment Screening Hits. Acs Chem Neurosci, 13, 2022
1GT7	L-rhamnulose-1-phosphate aldolase from Escherichia coli 分子名称: PHOSPHOGLYCOLOHYDROXAMIC ACID, RHAMNULOSE-1-PHOSPHATE ALDOLASE, ZINC ION 著者 Kroemer, M, Schulz, G.E. 登録日 2002-01-14 公開日 2002-05-03 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The Structure of L-Rhamnulose-1-Phosphate Aldolase (Class II) Solved by Low-Resolution Sir Phasing and 20-Fold Ncs Averaging Acta Crystallogr.,Sect.D, 58, 2002
8SUG	Cryo-EM structure of the wild type P. aeruginosa flagellar filament 分子名称: B-type flagellin 著者 Kreutzberger, M.A, Nedeljkovic, M, Egelman, E.H, Sundberg, E.J. 登録日 2023-05-12 公開日 2023-06-14 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 An unbroken network of interactions connecting flagellin domains is required for motility in viscous environments. Plos Pathog., 19, 2023
6CI9	RMM microcompartment-associated aminopropanol dehydrogenase NADP + aminoacetone holo-structure 分子名称: 1-aminopropan-2-one, 3-oxoacyl-[acyl-carrier-protein] reductase, CHLORIDE ION, ... 著者 Mallette, E, Kimber, M.S. 登録日 2018-02-23 公開日 2018-05-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure and Kinetics of the S-(+)-1-Amino-2-propanol Dehydrogenase from the RMM Microcompartment of Mycobacterium smegmatis. Biochemistry, 57, 2018
5NZZ	Crystal structure of phosphorylated p38aMAPK in complex with TAB1 分子名称: MAGNESIUM ION, Mitogen-activated protein kinase 14, NICKEL (II) ION, ... 著者 Nichols, C.E, De Nicola, G.F. 登録日 2017-05-15 公開日 2018-05-30 最終更新日 2018-09-19 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The TAB1-p38 alpha complex aggravates myocardial injury and can be targeted by small molecules. JCI Insight, 3, 2018
5O9Z	Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Homo sapiens RNA, U6 small nuclear 1 (RNU6-1), ... 著者 Bertram, K, Kastner, B. 登録日 2017-06-20 公開日 2017-08-16 最終更新日 2018-10-24 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation. Cell, 170, 2017
4ZL6	Crystal structure of the PmFTN variant E44H soaked in iron (3 h) 分子名称: FE (III) ION, Ferritin 著者 Pfaffen, S, Murphy, M.E.P. 登録日 2015-05-01 公開日 2015-09-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A Diatom Ferritin Optimized for Iron Oxidation but Not Iron Storage. J.Biol.Chem., 290, 2015
7LRX	Structure of HIV-1 Reverse Transcriptase in complex with DNA, L-dCTP, and CA(2+) ion 分子名称: 4-amino-1-{2-deoxy-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-L-erythro-pentofuranosyl}pyrimidin-2(1H)-one, AMMONIUM ION, CALCIUM ION, ... 著者 Hoang, A, Ruiz, F.X, Arnold, E. 登録日 2021-02-17 公開日 2022-02-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis of HIV inhibition by L-nucleosides: Opportunities for drug development and repurposing. Drug Discov Today, 27, 2022
2D6F	Crystal structure of Glu-tRNA(Gln) amidotransferase in the complex with tRNA(Gln) 分子名称: Glutamyl-tRNA(Gln) amidotransferase subunit D, Glutamyl-tRNA(Gln) amidotransferase subunit E, ZINC ION, ... 著者 Nureki, O. 登録日 2005-11-13 公開日 2006-07-11 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Structural basis of RNA-dependent recruitment of glutamine to the genetic code Science, 312, 2006
7UAV	Structure of Clostridium botulinum prophage Tad1 in apo state 分子名称: ABC transporter ATPase 著者 Lu, A, Leavitt, A, Yirmiya, E, Amitai, G, Garb, J, Morehouse, B.R, Hobbs, S.J, Sorek, R, Kranzusch, P.J. 登録日 2022-03-14 公開日 2022-10-05 最終更新日 2022-11-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Viruses inhibit TIR gcADPR signalling to overcome bacterial defence. Nature, 611, 2022
8B3B	Structure of metacyclic VSG (mVSG) 531 from Trypanosoma brucei 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Variant surface glycoprotein 531, alpha-D-mannopyranose, ... 著者 Chandra, M, Stebbins, C.E. 登録日 2022-09-16 公開日 2023-01-25 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.949 Å) 主引用文献 Structural similarities between the metacyclic and bloodstream form variant surface glycoproteins of the African trypanosome. Plos Negl Trop Dis, 17, 2023
4ZL5	Crystal structure of the PmFTN variant E44H soaked in iron (45 min) 分子名称: FE (III) ION, Ferritin 著者 Pfaffen, S, Murphy, M.E.P. 登録日 2015-05-01 公開日 2015-09-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 A Diatom Ferritin Optimized for Iron Oxidation but Not Iron Storage. J.Biol.Chem., 290, 2015
5CRK	Crystal Structure of the MTERF1 F243A substitution bound to the termination sequence. 分子名称: DNA (5'-D(*AP*TP*TP*AP*CP*CP*GP*GP*GP*CP*TP*CP*TP*GP*CP*CP*AP*TP*CP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*CP*CP*CP*GP*GP*TP*AP*AP*T)-3'), Transcription termination factor 1, ... 著者 Byrnes, J, Hauser, K, Norona, L, Mejia, E, Simmerling, C, Garcia-Diaz, M. 登録日 2015-07-23 公開日 2015-11-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Base Flipping by MTERF1 Can Accommodate Multiple Conformations and Occurs in a Stepwise Fashion. J.Mol.Biol., 428, 2016

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