1H48

The structure of 2C-Methyl-D-erythritol 2,4-cyclodiphosphate synthase in complex with CMP and product

Summary for 1H48

• Entry DOI: 10.2210/pdb1h48/pdb
• Related: 1GX1 1H47 1JY8 1KNJ 1KNK
• Descriptor: 2C-METHYL-D-ERYTHRITOL-2,4-CYCLODIPHOSPHATE SYNTHASE, 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE, ZINC ION, ... (7 entities in total)
• Functional Keywords: synthase, isoprenoid, lyase, isoprene biosynthesis
• Biological source: ESCHERICHIA COLI
• Total number of polymer chains: 6
• Total formula weight: 107715.31

Authors

Kemp, L.E.,Alphey, M.S.,Bond, C.S.,Hunter, W.N. (deposition date: 2003-02-24, release date: 2004-12-22, Last modification date: 2023-12-13)

• Primary citation: Kemp, L.E.,Alphey, M.S.,Bond, C.S.,Ferguson, M.,Hecht, S.,Bacher, A.,Eisenreich, W.,Rohdich, F.,Hunter, W.N.; The Identification of Isoprenoids that Bind in the Intersubunit Cavity of Escherichia Coli 2C-Methyl-D-Erythritol-2,4-Cyclodiphosphate Synthase by Complementary Biophysical Methods; Acta Crystallogr.,Sect.D, 61:45-, 2005; PubMed: 15608374; DOI: 10.1107/S0907444904025971

Experimental method

X-RAY DIFFRACTION (2.3 Å)