6XFL
 
 | | Structural characterization of the type III secretion system pilotin-secretin complex InvH-InvG by NMR spectroscopy | | 分子名称: | Type 3 secretion system pilotin, Type 3 secretion system secretin | | 著者 | Majewski, D.D, Okon, M, Heinkel, F, Robb, C.S, Vuckovic, M, McIntosh, L.P, Strynadka, N.C.J. | | 登録日 | 2020-06-15 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Characterization of the Pilotin-Secretin Complex from the Salmonella enterica Type III Secretion System Using Hybrid Structural Methods.
Structure, 29, 2021
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6N12
 | | Structure of GTPase Domain of Human Septin 7 at High Resolution | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Septin-7 | | 著者 | Brognara, G, Pereira, H.M, Brandao-Neto, J, Araujo, A.P.U, Garratt, R.C. | | 登録日 | 2018-11-08 | | 公開日 | 2019-05-01 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Revisiting SEPT7 and the slippage of beta-strands in the septin family.
J.Struct.Biol., 207, 2019
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7WZ6
 | | Crystal structure of MyoD-E47 | | 分子名称: | Isoform E47 of Transcription factor E2-alpha, Myoblast determination protein 1 | | 著者 | Zhong, J, Huang, Y, Ma, J. | | 登録日 | 2022-02-17 | | 公開日 | 2022-06-22 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural basis of the bHLH domains of MyoD-E47 heterodimer.
Biochem.Biophys.Res.Commun., 621, 2022
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7Z8N
 | | GacS histidine kinase from Pseudomonas aeruginosa | | 分子名称: | CALCIUM ION, Histidine kinase, R-1,2-PROPANEDIOL | | 著者 | Fadel, F, Bassim, V, Francis, V.I, Porter, S.L, Botzanowski, T, Legrand, P, Bourne, Y, Cianferani, S, Vincent, F. | | 登録日 | 2022-03-17 | | 公開日 | 2022-07-13 | | 最終更新日 | 2023-01-25 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Insights into the atypical autokinase activity of the Pseudomonas aeruginosa GacS histidine kinase and its interaction with RetS.
Structure, 30, 2022
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5IZ6
 | | Protein-protein interaction | | 分子名称: | Adenomatous polyposis coli protein, DI(HYDROXYETHYL)ETHER, PHQ-ALA-GLY-GLU-ALA-LEU-TYR-GLU-NH2, ... | | 著者 | Zhao, Y, Jiang, H, Yang, X, Jiang, F, Song, K, Zhang, J. | | 登録日 | 2016-03-25 | | 公開日 | 2017-07-05 | | 最終更新日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration.
Nat. Chem. Biol., 13, 2017
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5NC8
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5ND9
 | | Hibernating ribosome from Staphylococcus aureus (Rotated state) | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Khusainov, I, Vicens, Q, Ayupov, R, Usachev, K, Myasnikov, A, Simonetti, A, Validov, S, Kieffer, B, Yusupova, G, Yusupov, M, Hashem, Y. | | 登録日 | 2017-03-07 | | 公開日 | 2017-06-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structures and dynamics of hibernating ribosomes from Staphylococcus aureus mediated by intermolecular interactions of HPF.
EMBO J., 36, 2017
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6YTF
 | | Acinetobacter baumannii ribosome-tigecycline complex - 30S subunit head | | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S13, ... | | 著者 | Nicholson, D, Edwards, T.A, O'Neill, A.J, Ranson, N.A. | | 登録日 | 2020-04-24 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structure of the 70S Ribosome from the Human Pathogen Acinetobacter baumannii in Complex with Clinically Relevant Antibiotics.
Structure, 28, 2020
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6CF2
 | | Crystal structure of HIV-1 Rev (residues 1-93)-RNA aptamer complex | | 分子名称: | Anti-Rev Antibody, heavy chain, light chain, ... | | 著者 | Eren, E, Dearborn, A.D, Wingfield, P.T. | | 登録日 | 2018-02-13 | | 公開日 | 2018-07-25 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure of an RNA Aptamer that Can Inhibit HIV-1 by Blocking Rev-Cognate RNA (RRE) Binding and Rev-Rev Association.
Structure, 26, 2018
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6SRX
 | | Structure of the arginase-2-inhibitory human antigen-binding fragment Fab C0021158 | | 分子名称: | ACETATE ION, CHLORIDE ION, Fab C0021158 heavy chain (IgG1), ... | | 著者 | Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M. | | 登録日 | 2019-09-06 | | 公開日 | 2020-06-10 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Mabs, 12
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6YY0
 | | bovine ATP synthase F1-peripheral stalk domain, state 1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F(0) complex subunit B1, ... | | 著者 | Spikes, T, Montgomery, M.G, Walker, J.E. | | 登録日 | 2020-05-04 | | 公開日 | 2020-09-09 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | | 主引用文献 | Structure of the dimeric ATP synthase from bovine mitochondria.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6SV1
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6YXA
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5NOO
 | | Crystal Structure of C.elegans Thymidylate Synthase in Complex with dUMP and Tomudex | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, TOMUDEX, Thymidylate synthase | | 著者 | Wilk, P, Jarmula, A, Maj, P, Dowiercial, A, Banaszak, K, Rypniewski, W, Rode, W. | | 登録日 | 2017-04-12 | | 公開日 | 2017-05-03 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structures of nematode (parasitic T. spiralis and free living C. elegans), compared to mammalian, thymidylate synthases (TS). Molecular docking and molecular dynamics simulations in search for nematode-specific inhibitors of TS.
J. Mol. Graph. Model., 77, 2017
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5H8Q
 | | Structure of the human GluN1/GluN2A LBD in complex with GNE8324 | | 分子名称: | 6-[[ethyl-(4-fluorophenyl)amino]methyl]-2,3-dihydro-1~{H}-cyclopenta[3,4][1,3]thiazolo[1,4-~{a}]pyrimidin-8-one, ACETATE ION, GLUTAMIC ACID, ... | | 著者 | Wallweber, H.J.A, Lupardus, P.J. | | 登録日 | 2015-12-23 | | 公開日 | 2016-02-24 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function.
Neuron, 89, 2016
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8B2I
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7F75
 | | Cryo-EM structure of Spx-dependent transcription activation complex | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Lin, W, Feng, Y, Shi, J. | | 登録日 | 2021-06-28 | | 公開日 | 2021-10-13 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural basis of transcription activation by the global regulator Spx.
Nucleic Acids Res., 49, 2021
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6CAJ
 | | Electron cryo-microscopy of the eukaryotic translation initiation factor 2B from Homo sapiens | | 分子名称: | 2-(4-chloranylphenoxy)-~{N}-[4-[2-(4-chloranylphenoxy)ethanoylamino]cyclohexyl]ethanamide, Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, ... | | 著者 | Tsai, J.C, Miller-Vedam, L.E, Anand, A.A, Jaishankar, P, Nguyen, H.C, Renslo, A.R, Frost, A, Walter, P. | | 登録日 | 2018-01-31 | | 公開日 | 2018-04-11 | | 最終更新日 | 2019-11-20 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structure of the nucleotide exchange factor eIF2B reveals mechanism of memory-enhancing molecule.
Science, 359, 2018
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2VEB
 | | High resolution structure of protoglobin from Methanosarcina acetivorans C2A | | 分子名称: | GLYCEROL, OXYGEN MOLECULE, PHOSPHATE ION, ... | | 著者 | Nardini, M, Pesce, A, Thijs, L, Saito, J.A, Dewilde, S, Alam, M, Ascenzi, P, Coletta, M, Ciaccio, C, Moens, L, Bolognesi, M. | | 登録日 | 2007-10-18 | | 公開日 | 2008-01-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Archaeal Protoglobin Structure Indicates New Ligand Diffusion Paths and Modulation of Haem-Reactivity.
Embo Rep., 9, 2008
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8B2K
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6SRV
 | | Structure of the arginase-2-inhibitory human antigen-binding fragment Fab C0021144 | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | | 著者 | Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M. | | 登録日 | 2019-09-06 | | 公開日 | 2020-06-10 | | 最終更新日 | 2020-09-16 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Mabs, 12
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6BW0
 | | Nipah virus W protein C-terminus in complex with Importin alpha 1 | | 分子名称: | Importin subunit alpha-1, Protein W | | 著者 | Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. | | 登録日 | 2017-12-14 | | 公開日 | 2018-07-04 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
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6BWB
 | | Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 3 | | 分子名称: | Importin subunit alpha-3, Protein W | | 著者 | Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. | | 登録日 | 2017-12-14 | | 公開日 | 2018-07-04 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
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8AIF
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8J6E
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