5LV5
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![BU of 5lv5 by Molmil](/molmil-images/mine/5lv5) | Crystal structure of mouse PRMT6 in complex with inhibitor LH1458 | 分子名称: | 2-[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]ethyl-[[4-azanyl-1-(methoxymethyl)-2-oxidanylidene-pyrimidin-5-yl]methyl]-[(3~{S})-3-azanyl-4-oxidanyl-4-oxidanylidene-butyl]azanium, Protein arginine N-methyltransferase 6 | 著者 | Cura, V, Marechal, N, Troffer-Charlier, N, Halby, L, Arimondo, P, Bonnefond, L, Cavarelli, J. | 登録日 | 2016-09-12 | 公開日 | 2017-09-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | 主引用文献 | Hijacking DNA methyltransferase transition state analogues to produce chemical scaffolds for PRMT inhibitors. Philos. Trans. R. Soc. Lond., B, Biol. Sci., 373, 2018
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1DD9
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![BU of 1dd9 by Molmil](/molmil-images/mine/1dd9) | STRUCTURE OF THE DNAG CATALYTIC CORE | 分子名称: | DNA PRIMASE, STRONTIUM ION | 著者 | Keck, J.L, Roche, D.D, Lynch, A.S, Berger, J.M. | 登録日 | 1999-11-09 | 公開日 | 2000-04-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure of the RNA polymerase domain of E. coli primase. Science, 287, 2000
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2ZKG
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![BU of 2zkg by Molmil](/molmil-images/mine/2zkg) | Crystal structure of unliganded SRA domain of mouse Np95 | 分子名称: | 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase UHRF1 | 著者 | Arita, K, Ariyoshi, M, Tochio, H, Nakamura, Y, Shirakawa, M. | 登録日 | 2008-03-19 | 公開日 | 2008-09-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism Nature, 455, 2008
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1DDE
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![BU of 1dde by Molmil](/molmil-images/mine/1dde) | STRUCTURE OF THE DNAG CATALYTIC CORE | 分子名称: | DNA PRIMASE, YTTRIUM ION | 著者 | Keck, J.L, Roche, D.D, Lynch, A.S, Berger, J.M. | 登録日 | 1999-11-09 | 公開日 | 2000-04-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of the RNA polymerase domain of E. coli primase. Science, 287, 2000
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5XFR
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![BU of 5xfr by Molmil](/molmil-images/mine/5xfr) | Ternary complex of MTF2, DNA and histone | 分子名称: | DNA (5'-D(*GP*GP*GP*CP*GP*GP*CP*CP*GP*CP*CP*CP*T)-3'), Metal-response element-binding transcription factor 2, Peptide from Histone H3.1, ... | 著者 | Wang, Z, Li, H. | 登録日 | 2017-04-11 | 公開日 | 2017-09-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Polycomb-like proteins link the PRC2 complex to CpG islands Nature, 549, 2017
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7PLA
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![BU of 7pla by Molmil](/molmil-images/mine/7pla) | |
6QHD
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![BU of 6qhd by Molmil](/molmil-images/mine/6qhd) | Lysine acetylated and tyrosine phosphorylated STAT3 in a complex with DNA | 分子名称: | DNA (5'-D(*AP*AP*GP*AP*TP*TP*TP*AP*CP*GP*GP*GP*AP*AP*AP*TP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*AP*TP*TP*TP*CP*CP*CP*GP*TP*AP*AP*AP*TP*CP*T)-3'), Signal transducer and activator of transcription 3 | 著者 | Arbely, E, Belo, Y, Shahar, A, Zarivach, R. | 登録日 | 2019-01-16 | 公開日 | 2019-06-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Unexpected implications of STAT3 acetylation revealed by genetic encoding of acetyl-lysine. Biochim Biophys Acta Gen Subj, 1863, 2019
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7VOV
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5EYO
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![BU of 5eyo by Molmil](/molmil-images/mine/5eyo) | The crystal structure of the Max bHLH domain in complex with 5-carboxyl cytosine DNA | 分子名称: | DNA (5'-D(*AP*GP*TP*AP*GP*CP*AP*(1CC)P*GP*TP*GP*CP*TP*AP*CP*T)-3'), Protein max | 著者 | Wang, D, Hashimoto, H, Zhang, X, Cheng, X. | 登録日 | 2015-11-25 | 公開日 | 2016-12-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | MAX is an epigenetic sensor of 5-carboxylcytosine and is altered in multiple myeloma. Nucleic Acids Res., 45, 2017
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6J4G
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![BU of 6j4g by Molmil](/molmil-images/mine/6j4g) | Crystal structure of the AtWRKY33 domain | 分子名称: | DNA (5'-D(*AP*GP*CP*CP*TP*TP*TP*GP*AP*CP*CP*AP*GP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*CP*TP*GP*GP*TP*CP*AP*AP*AP*GP*GP*C)-3'), Probable WRKY transcription factor 33, ... | 著者 | Xu, Y.P, Xu, H, Wang, B, Su, X.D. | 登録日 | 2019-01-08 | 公開日 | 2020-01-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of the N-terminal DNA binding domain of AtWRKY33 To Be Published
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8G0Z
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![BU of 8g0z by Molmil](/molmil-images/mine/8g0z) | |
6PQU
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![BU of 6pqu by Molmil](/molmil-images/mine/6pqu) | Cryo-EM structure of HzTransib/nicked TIR substrate DNA pre-reaction complex (PRC) | 分子名称: | DNA (5'-D(P*AP*TP*CP*TP*GP*GP*CP*CP*TP*AP*GP*AP*TP*CP*T)-3'), DNA (5'-D(P*CP*AP*CP*GP*GP*TP*GP*GP*AP*TP*CP*GP*AP*AP*AP*A)-3'), DNA-mediated transposase, ... | 著者 | Liu, C, Yang, Y, Schatz, D.G. | 登録日 | 2019-07-10 | 公開日 | 2019-10-09 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structures of a RAG-like transposase during cut-and-paste transposition. Nature, 575, 2019
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7RHZ
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3D2W
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![BU of 3d2w by Molmil](/molmil-images/mine/3d2w) | |
6M9M
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6PQR
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![BU of 6pqr by Molmil](/molmil-images/mine/6pqr) | Cryo-EM structure of HzTransib/intact TIR substrate DNA pre-reaction complex (PRC) | 分子名称: | DNA (5'-D(*CP*TP*AP*GP*AP*TP*CP*TP*CP*AP*CP*GP*GP*TP*GP*GP*AP*TP*CP*GP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*CP*GP*AP*TP*CP*CP*AP*CP*CP*GP*TP*GP*AP*GP*AP*TP*CP*TP*AP*G)-3'), DNA-mediated transposase, ... | 著者 | Liu, C, Yang, Y, Schatz, D.G. | 登録日 | 2019-07-09 | 公開日 | 2019-10-09 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structures of a RAG-like transposase during cut-and-paste transposition. Nature, 575, 2019
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5FPR
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![BU of 5fpr by Molmil](/molmil-images/mine/5fpr) | Structure of Bacterial DNA Ligase with small-molecule ligand pyrimidin-2-amine (AT371) in an alternate binding site. | 分子名称: | DNA LIGASE, PYRIMIDIN-2-AMINE, SULFATE ION | 著者 | Jhoti, H, Ludlow, R.F, Pathuri, P, Saini, H.K, Tickle, I.J, Tisi, D, Verdonk, M, Williams, P.A. | 登録日 | 2015-12-02 | 公開日 | 2015-12-16 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Detection of Secondary Binding Sites in Proteins Using Fragment Screening. Proc.Natl.Acad.Sci.USA, 112, 2015
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6P0G
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6PQY
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7O24
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5ZAD
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![BU of 5zad by Molmil](/molmil-images/mine/5zad) | Human topoisomerase II beta in complex with DNA | 分子名称: | DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), DNA topoisomerase 2-beta | 著者 | Sun, L.Y, Zhu, L.W, Tang, Y.J. | 登録日 | 2018-02-07 | 公開日 | 2019-03-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | 主引用文献 | Increasing the distance between two monomers of topoisomerase II beta under the action of antitumor agent 4 beta-sulfur-(benzimidazole) 4'-demethylepipodophyllotoxin. Sci Rep, 8, 2018
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8E9A
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![BU of 8e9a by Molmil](/molmil-images/mine/8e9a) | Crystal structure of AsfvPolX in complex with 10-23 DNAzyme and Mg | 分子名称: | DNA/RNA (52-MER), MAGNESIUM ION, Repair DNA polymerase X, ... | 著者 | Cramer, E.R, Robart, A.R, Kaya, A.I. | 登録日 | 2022-08-26 | 公開日 | 2023-06-21 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Structure of a 10-23 deoxyribozyme exhibiting a homodimer conformation. Commun Chem, 6, 2023
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5HSO
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![BU of 5hso by Molmil](/molmil-images/mine/5hso) | Crystal structure of MYCOBACTERIUM TUBERCULOSIS MARR FAMILY PROTEIN Rv2887 complex with DNA | 分子名称: | DNA (30-MER), the upstream sequence of Rv0560c, Uncharacterized HTH-type transcriptional regulator Rv2887 | 著者 | Gao, Y.R, Li, D.F, Wang, D.C, Bi, L.J. | 登録日 | 2016-01-26 | 公開日 | 2017-02-01 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural analysis of the regulatory mechanism of MarR protein Rv2887 in M. tuberculosis Sci Rep, 7, 2017
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6S6V
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![BU of 6s6v by Molmil](/molmil-images/mine/6s6v) | Resting state of the E. coli Mre11-Rad50 (SbcCD) head complex bound to ATPgS | 分子名称: | MAGNESIUM ION, MANGANESE (II) ION, Nuclease SbcCD subunit C, ... | 著者 | Kaeshammer, L, Saathoff, J.H, Gut, F, Bartho, J, Alt, A, Kessler, B, Lammens, K, Hopfner, K.P. | 登録日 | 2019-07-03 | 公開日 | 2019-09-04 | 最終更新日 | 2019-11-20 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Mechanism of DNA End Sensing and Processing by the Mre11-Rad50 Complex. Mol.Cell, 76, 2019
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7DVV
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![BU of 7dvv by Molmil](/molmil-images/mine/7dvv) | Heme sensor protein PefR from Streptococcus agalactiae bound to operator DNA (28-mer) | 分子名称: | DNA (28-MER), HTH marR-type domain-containing protein | 著者 | Nishinaga, M, Nagai, S, Nishitani, Y, Sugimoto, H, Shiro, Y, Sawai, H. | 登録日 | 2021-01-15 | 公開日 | 2021-09-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Heme controls the structural rearrangement of its sensor protein mediating the hemolytic bacterial survival. Commun Biol, 4, 2021
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