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8S1X
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Crystal structure of Actinonin-bound PDF1 and the computationally designed DBAct553_1 protein binder
分子名称: ACTINONIN, DBAct553_1, FORMIC ACID, ...
著者Marchand, A, Pacesa, M, Correia, B.E.
登録日2024-02-16
公開日2024-10-30
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Targeting hybrid neosurface fingerprints for the design of de novo drug-induced protein interactions
To Be Published
8YBX
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BU of 8ybx by Molmil
Structure of the FADD/Caspase-8/cFLIP death effector domain assembly
分子名称: CASP8 and FADD-like apoptosis regulator subunit p43, Caspase-8 subunit p10, FAS-associated death domain protein
著者Lin, S.-C, Yang, C.-Y.
登録日2024-02-16
公開日2024-05-15
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献Deciphering DED assembly mechanisms in FADD-procaspase-8-cFLIP complexes regulating apoptosis.
Nat Commun, 15, 2024
8W1N
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BU of 8w1n by Molmil
Structure of transthyretin pathogenic mutation A120S
分子名称: Transthyretin
著者Ferguson, J.A, Stanfield, R.L, Wright, P.E.
登録日2024-02-16
公開日2024-02-28
最終更新日2024-08-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Mispacking of the F87 sidechain drives aggregation-promoting conformational fluctuations in the subunit interfaces of the transthyretin tetramer.
Protein Sci., 33, 2024
8W1L
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BU of 8w1l by Molmil
Structure of CSF1R kinase domain in complex with Cpd 32
分子名称: GLYCEROL, Macrophage colony-stimulating factor 1 receptor,CSF1R, SULFATE ION, ...
著者Kothe, M, Chodaparambil, J.
登録日2024-02-16
公開日2024-05-29
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Identification of Selective Imidazopyridine CSF1R Inhibitors.
Acs Med.Chem.Lett., 15, 2024
8S1M
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BU of 8s1m by Molmil
Crystal structure of human GABARAP fused to EGFR (1076-1099)
分子名称: CHLORIDE ION, Epidermal growth factor receptor,Gamma-aminobutyric acid receptor-associated protein, GLYCEROL
著者Ueffing, A, Willbold, D, Weiergraeber, O.H.
登録日2024-02-15
公開日2024-08-14
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of human GABARAP fused to EGFR (1076-1099)
To Be Published
8S1K
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BU of 8s1k by Molmil
Crystal Structure of human FABP4 in complex with 2-[1-(methoxymethyl)cyclopentyl]-6-pentyl-4-phenyl-3-(1H-tetrazol-5-yl)-5,6,7,8-tetrahydroquinoline
分子名称: (6~{S})-2-[1-(methoxymethyl)cyclopentyl]-6-pentyl-4-phenyl-3-(1~{H}-1,2,3,4-tetrazol-5-yl)-5,6,7,8-tetrahydroquinoline, DIMETHYL SULFOXIDE, Fatty acid-binding protein, ...
著者Ehler, A, Benz, J, Obst-Sander, U, Rudolph, M.G.
登録日2024-02-15
公開日2024-03-06
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献Crystal Structure of a human FABP4 complex
To be published
8W1D
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BU of 8w1d by Molmil
CRYSTAL STRUCTURE OF DPS-LIKE PROTEIN PA4880 FROM PSEUDOMONAS AERUGINOSA (DIMERIC FORM)
分子名称: DPS-LIKE PROTEIN, FE (II) ION
著者Lovell, S, Battaile, K.P, Rivera, M.
登録日2024-02-15
公開日2024-05-29
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Pseudomonas aeruginosa gene PA4880 encodes a Dps-like protein with a Dps fold, bacterioferritin-type ferroxidase centers, and endonuclease activity.
Front Mol Biosci, 11, 2024
8W1E
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BU of 8w1e by Molmil
Crystal Structure of DPS-like protein PA4880 from Pseudomonas aeruginosa (dodecamer)
分子名称: DPS-LIKE PROTEIN, FE (II) ION, SULFATE ION
著者Lovell, S, Liu, L, Seibold, S, Battaile, K.P, Rivera, M.
登録日2024-02-15
公開日2024-05-29
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Pseudomonas aeruginosa gene PA4880 encodes a Dps-like protein with a Dps fold, bacterioferritin-type ferroxidase centers, and endonuclease activity.
Front Mol Biosci, 11, 2024
8W1F
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BU of 8w1f by Molmil
Crystal Structure of DPS-like protein PA4880 from Pseudomonas aeruginosa (dodecamer, Mg bound)
分子名称: DPS-LIKE PROTEIN, FE (II) ION, MAGNESIUM ION, ...
著者Lovell, S, Liu, L, Seibold, S, Battaile, K.P, Rivera, M.
登録日2024-02-15
公開日2024-05-29
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Pseudomonas aeruginosa gene PA4880 encodes a Dps-like protein with a Dps fold, bacterioferritin-type ferroxidase centers, and endonuclease activity.
Front Mol Biosci, 11, 2024
8W18
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The crystal structure of the Michaelis-Menten complex of a C1s/C1-INH at 3.94 Angstroms
分子名称: Complement C1s subcomponent heavy chain, Complement C1s subcomponent light chain, Plasma protease C1 inhibitor
著者Garrigues, R.J, Garcia, B.L.
登録日2024-02-15
公開日2024-06-26
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.94 Å)
主引用文献The Crystal Structure of the Michaelis-Menten Complex of C1 Esterase Inhibitor and C1s Reveals Novel Insights into Complement Regulation.
J Immunol., 213, 2024
8S0N
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BU of 8s0n by Molmil
Crystal structure of the TMPRSS2 zymogen in complex with the nanobody A07
分子名称: Transmembrane protease serine 2, nanobody A07
著者Duquerroy, S, Fernandez, I, Rey, F.
登録日2024-02-14
公開日2024-06-26
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis of TMPRSS2 zymogen activation and recognition by the HKU1 seasonal coronavirus.
Cell, 187, 2024
8YBK
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BU of 8ybk by Molmil
Cryo-EM structure of the human nucleosome containing the H3.1 E97K mutant
分子名称: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Kimura, T, Hirai, S, Kujirai, T, Ogasawara, M, Takizawa, Y, Kurumizaka, H.
登録日2024-02-14
公開日2024-07-24
最終更新日2024-09-11
実験手法ELECTRON MICROSCOPY (2.69 Å)
主引用文献Cryo-EM structure and biochemical analyses of the nucleosome containing the cancer-associated histone H3 mutation E97K.
Genes Cells, 29, 2024
8YBJ
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BU of 8ybj by Molmil
Cryo-EM structure of human nucleosome core particle composed of the Widom 601 DNA sequence
分子名称: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Kimura, T, Hirai, S, Kujirai, T, Ogasawara, M, Takizawa, Y, Kurumizaka, H.
登録日2024-02-14
公開日2024-07-24
最終更新日2024-09-11
実験手法ELECTRON MICROSCOPY (2.38 Å)
主引用文献Cryo-EM structure and biochemical analyses of the nucleosome containing the cancer-associated histone H3 mutation E97K.
Genes Cells, 29, 2024
8S0U
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BU of 8s0u by Molmil
Structure of the LytM domain of PrgK from E. faecalis
分子名称: PrgK
著者Sun, W.-S, Berntsson, R.P.-A.
登録日2024-02-14
公開日2024-02-28
最終更新日2024-08-28
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Breaking barriers: pCF10 type 4 secretion system relies on a self-regulating muramidase to modulate the cell wall.
Mbio, 15, 2024
8W0U
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BU of 8w0u by Molmil
Human LCAD complexed with Acetoacetyl Coenzyme A
分子名称: ACETOACETYL-COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE, Long-chain specific acyl-CoA dehydrogenase, ...
著者Xia, C, Kim, J.J.P.
登録日2024-02-14
公開日2024-06-19
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for expanded substrate specificities of human long chain acyl-CoA dehydrogenase and related acyl-CoA dehydrogenases.
Sci Rep, 14, 2024
8W0T
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BU of 8w0t by Molmil
Human LCAD
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Long-chain specific acyl-CoA dehydrogenase, mitochondrial
著者Xia, C, Kim, J.J.P.
登録日2024-02-14
公開日2024-06-19
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for expanded substrate specificities of human long chain acyl-CoA dehydrogenase and related acyl-CoA dehydrogenases.
Sci Rep, 14, 2024
8W0Z
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BU of 8w0z by Molmil
Human LCAD complexed with Lauric Acid
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, LAURIC ACID, Long-chain specific acyl-CoA dehydrogenase, ...
著者Xia, C, Kim, J.J.P.
登録日2024-02-14
公開日2024-06-19
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for expanded substrate specificities of human long chain acyl-CoA dehydrogenase and related acyl-CoA dehydrogenases.
Sci Rep, 14, 2024
8W0I
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BU of 8w0i by Molmil
Cryo-EM structure of the human MCM2-7 heterohexamer
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA replication licensing factor MCM2, ...
著者Yang, R, Hunker, O, Bleichert, F.
登録日2024-02-13
公開日2024-10-02
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Multiple pathways for licensing human replication origins
To Be Published
8W0G
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BU of 8w0g by Molmil
Cryo-EM structure of a human MCM2-7 dimer
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA replication licensing factor MCM2, ...
著者Yang, R, Hunker, O, Bleichert, F.
登録日2024-02-13
公開日2024-10-02
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Multiple pathways for licensing human replication origins
To Be Published
8W0F
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BU of 8w0f by Molmil
Cryo-EM structure of a human MCM2-7 double hexamer on dsDNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (47-MER), ...
著者Hunker, O, Yang, R, Bleichert, F.
登録日2024-02-13
公開日2024-10-02
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Multiple pathways for licensing human replication origins
To Be Published
8S09
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BU of 8s09 by Molmil
H. sapiens MCM2-7 double hexamer bound to double stranded DNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (45-mer), ...
著者Greiwe, J.F, Weissmann, F, Diffley, J.F.X, Costa, A.
登録日2024-02-13
公開日2024-10-02
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献MCM Double Hexamer Loading Visualised with Human Proteins
Nature, 2024
8S0C
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BU of 8s0c by Molmil
H. sapiens ORC1-5 bound to double stranded DNA as part of the MCM-ORC complex
分子名称: DNA (26-mer), Isoform 2 of Origin recognition complex subunit 3, MAGNESIUM ION, ...
著者Greiwe, J.F, Weissmann, F, Diffley, J.F.X, Costa, A.
登録日2024-02-13
公開日2024-10-02
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献MCM Double Hexamer Loading Visualised with Human Proteins
Nature, 2024
8S0D
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BU of 8s0d by Molmil
H. sapiens MCM bound to double stranded DNA and ORC1-6
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (58-mer), DNA replication licensing factor MCM2, ...
著者Greiwe, J.F, Weissmann, F, Diffley, J.F.X, Costa, A.
登録日2024-02-13
公開日2024-10-02
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献MCM Double Hexamer Loading Visualised with Human Proteins
Nature, 2024
8S0B
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BU of 8s0b by Molmil
H. sapiens MCM bound to double stranded DNA and ORC6 as part of the MCM-ORC complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (45-mer), DNA replication licensing factor MCM2, ...
著者Greiwe, J.F, Weissmann, F, Diffley, J.F.X, Costa, A.
登録日2024-02-13
公開日2024-10-02
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献MCM Double Hexamer Loading Visualised with Human Proteins
Nature, 2024
8S0F
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BU of 8s0f by Molmil
H. sapiens OC1M bound to double stranded DNA
分子名称: DNA (39-mer), DNA replication factor Cdt1, DNA replication licensing factor MCM2, ...
著者Greiwe, J.F, Weissmann, F, Diffley, J.F.X, Costa, A.
登録日2024-02-13
公開日2024-10-02
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献MCM Double Hexamer Loading Visualised with Human Proteins
Nature, 2024

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件を2024-11-13に公開中

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