PDB: 37819 件ウェブページステータス検索Chemie searchBIRD

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5KFM	Human DNA polymerase eta-DNA ternary complex with Sp-dATP-alpha-S: ground state at pH7.0 (K+ MES) with 1 Ca2+ ion 分子名称: 2'-DEOXYADENOSINE 5'-O-(1-THIOTRIPHOSPHATE), CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... 著者 Gao, Y, Yang, W. 登録日 2016-06-12 公開日 2016-06-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352, 2016
5KFW	Human DNA polymerase eta R61A-DNA ternary complex: reaction with 1 mM Mg2+ for 200s 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... 著者 Gao, Y, Yang, W. 登録日 2016-06-12 公開日 2016-06-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352, 2016
5KQR	Structure of NS5 methyltransferase from Zika virus bound to S-adenosylmethionine 分子名称: CHLORIDE ION, Methyltransferase, PHOSPHATE ION, ... 著者 Jain, R, Coloma, J, Rajashankar, K.R, Aggarwal, A.K. 登録日 2016-07-06 公開日 2016-09-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.331 Å) 主引用文献 Structures of NS5 Methyltransferase from Zika Virus. Cell Rep, 16, 2016
5KNM	Human leukocyte antigen F (HLA-F) presents peptides and regulates immunity through interactions with NK-cell receptors 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Leukocyte immunoglobulin-like receptor subfamily B member 1, ... 著者 Dulberger, C.L, Adams, E.J. 登録日 2016-06-28 公開日 2017-06-14 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Human Leukocyte Antigen F Presents Peptides and Regulates Immunity through Interactions with NK Cell Receptors. Immunity, 46, 2017
5L7H	MCR IN COMPLEX WITH ligand 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 3-methyl-5,8-dioxa-17lambda-thia-4,18-diazatetracyclo[18.2.2.1,.0]pentacosa-1(22),2(6),3,9,11,13(25),20,23-octaene-17,17-dione, Mineralocorticoid receptor, ... 著者 Xue, Y, Aagaard, A, Backstrom, S, Edman, K. 登録日 2016-06-03 公開日 2016-12-07 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Structure-Based Drug Design of Mineralocorticoid Receptor Antagonists to Explore Oxosteroid Receptor Selectivity. ChemMedChem, 12, 2017
8WV1	Ambient Temperature Structure of 50S Ribosomal Subunit from Thermus Thermophilus 分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L15, ... 著者 DeMirci, H, Tosun, B. 登録日 2023-10-22 公開日 2024-11-06 実験手法 X-RAY DIFFRACTION (3.99 Å) 主引用文献 Ambient Temperature Structure of 50S Ribosomal Subunit from Thermus Thermophilus To Be Published
6C67	Mycobacterium tuberculosis adenosine kinase bound to iodotubercidin 分子名称: (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL, Adenosine kinase, GLYCEROL, ... 著者 Crespo, R.A, TB Structural Genomics Consortium (TBSGC) 登録日 2018-01-17 公開日 2019-05-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase. J.Med.Chem., 62, 2019
5L7E	MCR IN COMPLEX WITH ligand 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ... 著者 Edman, K, Aagaard, A, Backstrom, S, Xue, Y. 登録日 2016-06-03 公開日 2016-12-07 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Structure-Based Drug Design of Mineralocorticoid Receptor Antagonists to Explore Oxosteroid Receptor Selectivity. ChemMedChem, 12, 2017
6C9V	Mycobacterium tuberculosis adenosine kinase bound to (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-(4-phenylpiperazin-1-yl)-9H-purin-9-yl)tetrahydrofuran-3,4-diol 分子名称: (2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-(4-phenylpiperazin-1-yl)-9H-purin-9-yl]tetrahydrofuran-3,4-diol, Adenosine kinase, GLYCEROL, ... 著者 Crespo, R.A, TB Structural Genomics Consortium (TBSGC) 登録日 2018-01-28 公開日 2019-05-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase. J.Med.Chem., 62, 2019
6C9R	Mycobacterium tuberculosis adenosine kinase bound to (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-(thiophen-3-yl)-9H-purin-9-yl)tetrahydrofuran-3,4-diol 分子名称: 9-beta-D-ribofuranosyl-6-(thiophen-3-yl)-9H-purine, Adenosine kinase, GLYCEROL, ... 著者 Crespo, R.A, TB Structural Genomics Consortium (TBSGC) 登録日 2018-01-28 公開日 2019-05-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase. J.Med.Chem., 62, 2019
6C9Q	Mycobacterium tuberculosis adenosine kinase bound to 5'-aminoadenosine 分子名称: 5'-amino-5'-deoxyadenosine, Adenosine kinase 著者 Crespo, R.A, TB Structural Genomics Consortium (TBSGC) 登録日 2018-01-28 公開日 2019-05-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase. J.Med.Chem., 62, 2019
5KU5	Crystal Structure of CusS Sensor Domain with Silver Bound 分子名称: ACETATE ION, SILVER ION, Sensor kinase CusS 著者 Affandi, T, Issaian, A.V, McEvoy, M.M. 登録日 2016-07-12 公開日 2016-09-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The Structure of the Periplasmic Sensor Domain of the Histidine Kinase CusS Shows Unusual Metal Ion Coordination at the Dimeric Interface. Biochemistry, 55, 2016
5L7G	MCR IN COMPLEX WITH ligand 分子名称: 1,2-ETHANEDIOL, Mineralocorticoid receptor, NCOA1 peptide, ... 著者 Edman, K, Aagaard, A, Backstrom, S, Xue, Y. 登録日 2016-06-03 公開日 2016-12-07 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Structure-Based Drug Design of Mineralocorticoid Receptor Antagonists to Explore Oxosteroid Receptor Selectivity. ChemMedChem, 12, 2017
8OQY	Structure of apo form of human gamma-secretase PSEN1 APH-1B isoform reconstituted into lipid nanodisc 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Odorcic, I, Chavez Gutierrez, L, Efremov, R.G. 登録日 2023-04-12 公開日 2024-04-24 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Apo and A beta 46-bound gamma-secretase structures provide insights into amyloid-beta processing by the APH-1B isoform. Nat Commun, 15, 2024
5L4G	The human 26S proteasome at 3.9 A 分子名称: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... 著者 Schweitzer, A, Aufderheide, A, Rudack, T, Beck, F. 登録日 2016-05-25 公開日 2016-09-07 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structure of the human 26S proteasome at a resolution of 3.9 angstrom. Proc.Natl.Acad.Sci.USA, 113, 2016
5L1I	Crystal Structure of Human DNA Polymerase Eta Inserting dCTP Opposite O6-Methyl-2'-deoxyguanosine 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*C)-3'), ... 著者 Patra, A, Egli, M. 登録日 2016-07-29 公開日 2016-10-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Mechanisms of Insertion of dCTP and dTTP Opposite the DNA Lesion O6-Methyl-2'-deoxyguanosine by Human DNA Polymerase eta. J.Biol.Chem., 291, 2016
3DT4	The structure of rat cytosolic PEPCK in complex with oxalate and GTP 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, OXALATE ION, ... 著者 Sullivan, S.M, Holyoak, T. 登録日 2008-07-14 公開日 2008-08-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection. Proc.Natl.Acad.Sci.Usa, 105, 2008
5KQS	Structure of NS5 methyltransferase from Zika virus bound to S-adenosylmethionine and 7-methyl-guanosine-5'-diphosphate 分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, ACETATE ION, GLYCEROL, ... 著者 Coloma, J, Jain, R, Rajashankar, K.R, Aggarwal, A.K. 登録日 2016-07-06 公開日 2016-09-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structures of NS5 Methyltransferase from Zika Virus. Cell Rep, 16, 2016
8X5B	Cryo-EM structures of human XPR1 in closed states 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHOLESTEROL, PHOSPHATE ION, ... 著者 Jiang, D.H, Yan, R. 登録日 2023-11-16 公開日 2024-07-03 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (2.84 Å) 主引用文献 Human XPR1 structures reveal phosphate export mechanism. Nature, 633, 2024
8X5E	Cryo-EM structure of human XPR1 in open state 分子名称: PHOSPHATE ION, Solute carrier family 53 member 1, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate 著者 Jiang, D.H, Yan, R. 登録日 2023-11-17 公開日 2024-07-03 最終更新日 2024-10-30 実験手法 ELECTRON MICROSCOPY (3.61 Å) 主引用文献 Human XPR1 structures reveal phosphate export mechanism. Nature, 633, 2024
4P70	Crystal Structure of Unmodified tRNA Proline (CGG) Bound to Codon CCG on the Ribosome 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Maehigashi, T, Dunkle, J.A, Dunham, C.M. 登録日 2014-03-25 公開日 2014-08-13 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (3.68 Å) 主引用文献 Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops. Proc.Natl.Acad.Sci.USA, 111, 2014
5L1L	PostInsertion complex of Human DNA Polymerase Eta bypassing an O6-Methyl-2'-deoxyguanosine : dT site 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*GP*(6OG)P*TP*GP*AP*CP*GP*CP*T)-3'), ... 著者 Patra, A, Egli, M. 登録日 2016-07-29 公開日 2016-10-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Mechanisms of Insertion of dCTP and dTTP Opposite the DNA Lesion O6-Methyl-2'-deoxyguanosine by Human DNA Polymerase eta. J.Biol.Chem., 291, 2016
4P6F	Crystal structure of the peptolide 12C bound to bacterial ribosome 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Fagan, C.E, Dunham, C.M. 登録日 2014-03-24 公開日 2014-10-01 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Macrolide-Peptide Conjugates as Probes of the Path of Travel of the Nascent Peptides through the Ribosome. Acs Chem.Biol., 9, 2014
5L2J	Crystal Structure of human CD1b in complex with C36-GMM 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-O-[(2R,3R)-3-hydroxy-2-tetradecyldocosanoyl]-alpha-L-idopyranose, ACETATE ION, ... 著者 Gras, S, Shahine, A, Le Nours, J, Rossjohn, J. 登録日 2016-08-02 公開日 2016-11-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 T cell receptor recognition of CD1b presenting a mycobacterial glycolipid. Nat Commun, 7, 2016
5L9X	Human DNA polymerase eta-DNA ternary complex: reaction with 10 mM Mn2+ for 60s 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... 著者 Gao, Y, Yang, W. 登録日 2016-06-12 公開日 2016-06-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352, 2016

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