5KFM
Human DNA polymerase eta-DNA ternary complex with Sp-dATP-alpha-S: ground state at pH7.0 (K+ MES) with 1 Ca2+ ion
Summary for 5KFM
Entry DOI | 10.2210/pdb5kfm/pdb |
Descriptor | DNA polymerase eta, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... (7 entities in total) |
Functional Keywords | in crystallo reaction, dna polymerase, metal ion dependent catalysis, replication, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 55505.32 |
Authors | |
Primary citation | Gao, Y.,Yang, W. Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352:1334-1337, 2016 Cited by PubMed: 27284197DOI: 10.1126/science.aad9633 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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