Human DNA polymerase eta-DNA ternary complex: reaction with 10 mM Mn2+ for 60s

Summary for 5L9X

DescriptorDNA polymerase eta, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ... (9 entities in total)
Functional Keywordsin crystallo reaction, dna polymerase, metal ion dependent catalysis, transferase
Biological sourceHomo sapiens (Human)
Cellular locationNucleus  Q9Y253
Total number of polymer chains3
Total molecular weight56141.22
Gao, Y.,Yang, W. (deposition date: 2016-06-12, release date: 2016-06-22, Last modification date: 2018-01-31)
Primary citation
Gao, Y.,Yang, W.
Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352:1334-1337, 2016
PubMed: 27284197 (PDB entries with the same primary citation)
DOI: 10.1126/science.aad9633
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.21640 1.1% 5.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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PDB entries from 2020-10-21