8WPV
 
 | | Truncated mutant (1-171) of ferritin from Ureaplasma diversum soaked in Fe2+ solution for 30min | | 分子名称: | CHLORIDE ION, FE (III) ION, MAGNESIUM ION, ... | | 著者 | Wang, W.M, Xi, H.F, Gong, W.J, Ma, D.Y, Wang, H.F. | | 登録日 | 2023-10-10 | | 公開日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (2.059 Å) | | 主引用文献 | Growth Process of Fe-O Nanoclusters with Different Sizes Biosynthesized by Protein Nanocages.
J.Am.Chem.Soc., 146, 2024
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8WBP
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8W0V
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9ATD
 | | Crystal structure of MERS 3CL protease in complex with a ethylcyclohexyl 2-pyrrolidone inhibitor (S-enantiomer) inhibitor | | 分子名称: | (1R,2S)-2-{[N-({[(2S)-1-(2-cyclohexylethyl)-5-oxopyrrolidin-2-yl]methoxy}carbonyl)-L-leucyl]amino}-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, (1S,2S)-2-{[N-({[(2S)-1-(2-cyclohexylethyl)-5-oxopyrrolidin-2-yl]methoxy}carbonyl)-L-leucyl]amino}-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase nsp5 | | 著者 | Liu, L, Lovell, S, Battaile, K.P, Dampalla, C.S, Groutas, W.C. | | 登録日 | 2024-02-26 | | 公開日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure-Guided Design of Potent Coronavirus Inhibitors with a 2-Pyrrolidone Scaffold: Biochemical, Crystallographic, and Virological Studies.
J.Med.Chem., 2024
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8VBW
 | | Structure of the monofunctional Staphylococcus aureus PBP1 in its beta-lactam (Ertapenem) inhibited form | | 分子名称: | (4R,5S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, Penicillin-binding protein 1 | | 著者 | Bon, C.G, Lee, J, Caveney, N.A, Strynadka, N.C.J. | | 登録日 | 2023-12-12 | | 公開日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1.
J.Struct.Biol., 216, 2024
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8UDT
 | | The X-RAY co-crystal structure of human FGFR3 and KIN-3248 | | 分子名称: | 3-[(1-cyclopropyl-4,6-difluoro-1H-benzimidazol-5-yl)ethynyl]-1-[(3R,5R)-5-(methoxymethyl)-1-propanoylpyrrolidin-3-yl]-5-(methylamino)-1H-pyrazole-4-carboxamide, D-MALATE, Fibroblast growth factor receptor 3 | | 著者 | Tyhonas, J.S, Arnold, L.D, Cox, J, Franovic, A, Gardiner, E, Grandinetti, K, Kania, R, Kanouni, T, Lardy, M, Li, C, Martin, E.S, Miller, N, Mohan, A, Murphy, E.A, Perez, M, Soroceanu, L, Timple, N, Uryu, S, Womble, S, Kaldor, S.W. | | 登録日 | 2023-09-29 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.829 Å) | | 主引用文献 | Discovery of KIN-3248, An Irreversible, Next Generation FGFR Inhibitor for the Treatment of Advanced Tumors Harboring FGFR2 and/or FGFR3 Gene Alterations.
J.Med.Chem., 67, 2024
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9FBX
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8XMZ
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8XN6
 | | The Crystal Structure of GSK3b from Biortus. | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Glycogen synthase kinase-3 beta, ... | | 著者 | Wang, F, Cheng, W, Yuan, Z, Qi, J, Wu, B. | | 登録日 | 2023-12-29 | | 公開日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The Crystal Structure of GSK3b from Biortus.
To Be Published
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8WD3
 | | The Crystal Structure of JMJD2A(M1-L359) from Biortus. | | 分子名称: | Lysine-specific demethylase 4A, NICKEL (II) ION, ZINC ION | | 著者 | Wang, F, Cheng, W, Lv, Z, Ju, C, Bao, C. | | 登録日 | 2023-09-14 | | 公開日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | The Crystal Structure of JMJD2A(M1-L359) from Biortus.
To Be Published
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8VM2
 | | Crystal Structure of NRAS Q61K bound to GTP | | 分子名称: | GTPase NRas, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Gebregiworgis, T, Chan, J.Y.L, Kuntz, D.A, Prive, G.G, Marshall, C.B, Ikura, M. | | 登録日 | 2024-01-12 | | 公開日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Crystal structure of NRAS Q61K with a ligand-induced pocket near switch II.
Eur J Cell Biol, 103, 2024
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8W0W
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8VW2
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8U78
 | | Structure of a N-Me-D-Gln4,Lys10-teixobactin analogue | | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, CHLORIDE ION, N-Methyl-D-Gln4,Lys10-teixobactin | | 著者 | Nowick, J.S, Yang, H, Kreutzer, A.G. | | 登録日 | 2023-09-14 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Supramolecular Interactions of Teixobactin Analogues in the Crystal State.
J.Org.Chem., 89, 2024
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8XFD
 | | Crystal structure of pyruvate kinase tetramer in complex with allosteric activator, Mitapivat (MTPV, AG-348) | | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, Isoform L-type of Pyruvate kinase PKLR, MAGNESIUM ION, ... | | 著者 | Sun, R, Achour, A. | | 登録日 | 2023-12-13 | | 公開日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | High Resolution Crystal Structure of the Pyruvate Kinase Tetramer in Complex with the Allosteric Activator Mitapivat/AG-348
Crystals, 2024
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8V7U
 | | PanDDA analysis -- Crystal Structure of Zika virus NS3 Helicase in complex with Z729726784 | | 分子名称: | 1,2-ETHANEDIOL, 2-cyclopentyl-N-(3-methyl-1,2,4-oxadiazol-5-yl)acetamide, DIMETHYL SULFOXIDE, ... | | 著者 | Godoy, A.S, Noske, G.D, Fairhead, M, Lithgo, R.M, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Marples, P.G, Ni, X, Tomlinson, C.W.E, Wild, C, Mesquita, N.C.M.R, Oliva, G, Fearon, D, Walsh, M.A, von Delft, F. | | 登録日 | 2023-12-04 | | 公開日 | 2023-12-20 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | PanDDA analysis -- Crystal Structure of Zika virus NS3 Helicase in complex with Z729726784
To Be Published
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8XP5
 | | The Crystal Structure of p53/BCL-xL fusion complex from Biortus. | | 分子名称: | Bcl-2-like protein 1,Cellular tumor antigen p53, ZINC ION | | 著者 | Wang, F, Cheng, W, Yuan, Z, Lin, D, Bao, C. | | 登録日 | 2024-01-03 | | 公開日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | The Crystal Structure of p53/BCL-xL fusion complex from Biortus.
To Be Published
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8W21
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8WFQ
 | | The Crystal Structure of RALDH1 from Biortus. | | 分子名称: | 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Aldehyde dehydrogenase 1A1 | | 著者 | Wang, F, Cheng, W, Lv, Z, Qi, J, Shen, Z. | | 登録日 | 2023-09-20 | | 公開日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | The Crystal Structure of RALDH1 from Biortus.
To Be Published
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8ZMN
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8TV1
 | | Structure of the EphA2 LBDCRD bound to FabS1C_L1 | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Ephrin type-A receptor 2, ... | | 著者 | Singer, A.U, Bruce, H.A, Blazer, L, Adams, J.J, Sicheri, F, Sidhu, S.S. | | 登録日 | 2023-08-17 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Synthetic Antibodies targeting EPHA2 Induce Diverse Signaling-Competent Clusters with Differential Activation
To be published
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8XPT
 | | The Crystal Structure of EHMT1 from Biortus. | | 分子名称: | Histone-lysine N-methyltransferase EHMT1, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... | | 著者 | Wang, F, Cheng, W, Yuan, Z, Lin, D, Bao, C. | | 登録日 | 2024-01-04 | | 公開日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | | 主引用文献 | The Crystal Structure of EHMT1 from Biortus.
To Be Published
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8ZBO
 | | Crystal structure of the biphotochromic fluorescent protein moxSAASoti (F97M variant) in its green on-state | | 分子名称: | 1,2-ETHANEDIOL, F97M variant of the biphotochromic fluorescent protein moxSAASoti, NITRATE ION, ... | | 著者 | Boyko, K.M, Matyuta, I.O, Marynich, N.K, Minyaev, M.E, Khadiyatova, A.A, Popov, V.O, Savitsky, A.P. | | 登録日 | 2024-04-26 | | 公開日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and fluorescent study of the in cellulo crystallizable fluorescent protein moxSAASoti F97M
To Be Published
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9BKW
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8VRU
 | | GII.4c apo norovirus protruding domain | | 分子名称: | 1,2-ETHANEDIOL, Capsid protein, FORMIC ACID | | 著者 | Kher, G, Prewitt, A, Pancera, M, Hansman, G. | | 登録日 | 2024-01-22 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | | 主引用文献 | Advancement of norovirus therapies
To Be Published
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