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7Y1T
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Complex of integrin alphaV/beta8 and L-TGF-beta1 at a ratio of 1:2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Duan, Z, Zhang, Z.
登録日2022-06-08
公開日2022-08-31
最終更新日2022-09-07
実験手法ELECTRON MICROSCOPY (3.24 Å)
主引用文献Specificity of TGF-beta 1 signal designated by LRRC33 and integrin alpha V beta 8.
Nat Commun, 13, 2022
7Y1R
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Human L-TGF-beta1 in complex with the anchor protein LRRC33
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Duan, Z, Zhang, Z.
登録日2022-06-08
公開日2022-08-31
最終更新日2022-09-07
実験手法ELECTRON MICROSCOPY (4.01 Å)
主引用文献Specificity of TGF-beta 1 signal designated by LRRC33 and integrin alpha V beta 8.
Nat Commun, 13, 2022
1SGH
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BU of 1sgh by Molmil
Moesin FERM domain bound to EBP50 C-terminal peptide
分子名称: Ezrin-radixin-moesin binding phosphoprotein 50, Moesin
著者Finnerty, C.M, Chambers, D, Ingraffea, J, Faber, H.R, Karplus, P.A, Bretscher, A.
登録日2004-02-23
公開日2004-06-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献The EBP50-moesin interaction involves a binding site regulated by direct masking on the FERM domain
J.Cell.Sci., 117, 2004
5Y44
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A novel moderator XD4 for bile acid receptor
分子名称: Bile acid receptor, Peptide from Nuclear receptor coactivator 1, SULFATE ION, ...
著者Lu, Y, Li, Y.
登録日2017-08-01
公開日2019-02-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献A novel moderator XD4 for bile acid receptor
To Be Published
1S9D
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ARF1[DELTA 1-17]-GDP-MG IN COMPLEX WITH BREFELDIN A AND A SEC7 DOMAIN
分子名称: 1,6,7,8,9,11A,12,13,14,14A-DECAHYDRO-1,13-DIHYDROXY-6-METHYL-4H-CYCLOPENT[F]OXACYCLOTRIDECIN-4-ONE, ADP-Ribosylation Factor 1, Arno, ...
著者Renault, L, Guibert, B, Cherfils, J.
登録日2004-02-04
公開日2004-02-10
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Snapshots of the Mechanism and Inhibition of a Guanine Nucleotide Exchange Factor
Nature, 426, 2003
5XZH
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Vitamin D receptor with a synthetic ligand ADRO2
分子名称: (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,6R)-6-(1-adamantyl)-6-oxidanyl-hex-4-yn-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol, Mediator of RNA polymerase II transcription subunit 1, Vitamin D3 receptor
著者Otero, R, Numoto, N, Ikura, T, Yamada, S, Mourino, A, Makishima, M, Ito, N.
登録日2017-07-12
公開日2018-07-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献25 S-Adamantyl-23-yne-26,27-dinor-1 alpha ,25-dihydroxyvitamin D3: Synthesis, Tissue Selective Biological Activities, and X-ray Crystal Structural Analysis of Its Vitamin D Receptor Complex.
J. Med. Chem., 61, 2018
2PG1
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BU of 2pg1 by Molmil
Structural analysis of a cytoplasmic dynein Light Chain-Intermediate Chain complex
分子名称: Cytoplasmic dynein 1 intermediate chain 2, Dynein light chain 1, cytoplasmic, ...
著者Williams, J.C, Hendrickson, W.A.
登録日2007-04-06
公開日2007-06-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and thermodynamic characterization of a cytoplasmic dynein light chain-intermediate chain complex
Proc.Natl.Acad.Sci.Usa, 104, 2007
2Q4G
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BU of 2q4g by Molmil
Ensemble refinement of the protein crystal structure of human ribonuclease inhibitor complexed with ribonuclease I
分子名称: CITRIC ACID, Ribonuclease inhibitor, Ribonuclease pancreatic
著者Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG)
登録日2007-05-31
公開日2007-06-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.954 Å)
主引用文献Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein.
J.Mol.Biol., 368, 2007
4GK0
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BU of 4gk0 by Molmil
Crystal structure of human Rev3-Rev7-Rev1 complex
分子名称: DNA polymerase zeta catalytic subunit, DNA repair protein REV1, Mitotic spindle assembly checkpoint protein MAD2B
著者Tao, J, Min, X, Wei, X.
登録日2012-08-10
公開日2013-03-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural insights into the assembly of human translesion polymerase complexes
Protein Cell, 3, 2012
5Y1J
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BU of 5y1j by Molmil
Crystal structure of human FXR in complex with a functional drug ligand
分子名称: 2-[[2-fluoranyl-4-(3-methoxyphenyl)phenyl]carbamoyl]cyclopentene-1-carboxylic acid, Bile acid receptor, Peptide from Nuclear receptor coactivator 2
著者Lu, Y, Li, Y.
登録日2017-07-20
公開日2018-10-31
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of human FXR in complex with a functional drug liagnd
To Be Published
2Q91
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BU of 2q91 by Molmil
Structure of the Ca2+-Bound Activated Form of the S100A4 Metastasis Factor
分子名称: CALCIUM ION, S100A4 Metastasis Factor
著者Malashkevich, V.N, Knight, D, Ramagopal, U.A, Almo, S.C, Bresnick, A.R.
登録日2007-06-12
公開日2008-02-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Structure of Ca(2+)-Bound S100A4 and Its Interaction with Peptides Derived from Nonmuscle Myosin-IIA.
Biochemistry, 47, 2008
1PRM
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BU of 1prm by Molmil
TWO BINDING ORIENTATIONS FOR PEPTIDES TO SRC SH3 DOMAIN: DEVELOPMENT OF A GENERAL MODEL FOR SH3-LIGAND INTERACTIONS
分子名称: C-SRC TYROSINE KINASE SH3 DOMAIN, PROLINE-RICH LIGAND PLR1 (AFAPPLPRR)
著者Feng, S, Chen, J.K, Yu, H, Simon, J.A, Schreiber, S.L.
登録日1994-10-10
公開日1995-02-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions.
Science, 266, 1994
1PRL
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BU of 1prl by Molmil
TWO BINDING ORIENTATIONS FOR PEPTIDES TO SRC SH3 DOMAIN: DEVELOPMENT OF A GENERAL MODEL FOR SH3-LIGAND INTERACTIONS
分子名称: C-SRC TYROSINE KINASE SH3 DOMAIN, PROLINE-RICH LIGAND PLR1 (AFAPPLPRR)
著者Feng, S, Chen, J.K, Yu, H, Simon, J.A, Schreiber, S.L.
登録日1994-10-10
公開日1995-02-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions.
Science, 266, 1994
3TAD
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BU of 3tad by Molmil
Crystal Structure of the Liprin-alpha/Liprin-beta complex
分子名称: GLYCEROL, Liprin-alpha-2, Liprin-beta-1
著者Wei, Z, Zheng, S, Yu, C, Zhang, M.
登録日2011-08-04
公開日2011-10-12
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Liprin-mediated large signaling complex organization revealed by the liprin-alpha/CASK and liprin-alpha/liprin-beta complex structures
Mol.Cell, 43, 2011
4GMX
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BU of 4gmx by Molmil
Crystal structure of KPT185 in complex with CRM1-Ran-RanBP1
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ...
著者Sun, Q, Chook, Y.M.
登録日2012-08-16
公開日2012-10-17
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia.
Blood, 120, 2012
7YAG
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BU of 7yag by Molmil
CryoEM structure of SPCA1a in E1-Ca-AMPPCP state subclass 1
分子名称: CALCIUM ION, Calcium-transporting ATPase type 2C member 1, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
著者Chen, Z, Watanabe, S, Inaba, K.
登録日2022-06-28
公開日2023-03-22
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus.
Sci Adv, 9, 2023
7YAH
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BU of 7yah by Molmil
CryoEM structure of SPCA1a in E1-Ca-AMPPCP state subclass 2
分子名称: CALCIUM ION, Calcium-transporting ATPase type 2C member 1, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
著者Chen, Z, Watanabe, S, Inaba, K.
登録日2022-06-28
公開日2023-03-22
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus.
Sci Adv, 9, 2023
7YAI
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CryoEM structure of SPCA1a in E1-Ca-AMPPCP state subclass 3
分子名称: CALCIUM ION, Calcium-transporting ATPase type 2C member 1, Nanobody head piece of megabody, ...
著者Chen, Z, Watanabe, S, Inaba, K.
登録日2022-06-28
公開日2023-03-22
実験手法ELECTRON MICROSCOPY (3.14 Å)
主引用文献Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus.
Sci Adv, 9, 2023
7YAJ
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BU of 7yaj by Molmil
CryoEM structure of SPCA1a in E1-Mn-AMPPCP state subclass 1
分子名称: Calcium-transporting ATPase type 2C member 1, MANGANESE (II) ION, Nanobody head piece of megabody, ...
著者Chen, Z, Watanabe, S, Inaba, K.
登録日2022-06-28
公開日2023-03-22
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus.
Sci Adv, 9, 2023
7YAM
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CryoEM structure of SPCA1a in E2P state
分子名称: BERYLLIUM TRIFLUORIDE ION, Calcium-transporting ATPase type 2C member 1, MAGNESIUM ION
著者Chen, Z, Watanabe, S, Inaba, K.
登録日2022-06-28
公開日2023-03-22
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus.
Sci Adv, 9, 2023
5Y49
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A moderator XD22 binding to bile acid receptor
分子名称: Bile acid receptor, Peptide from Nuclear receptor coactivator 2, [(1R,2S,4S)-2-bicyclo[2.2.1]heptanyl] 4-azanylbenzoate
著者Lu, Y, Li, Y.
登録日2017-08-02
公開日2019-02-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A moderator XD22 binding to bile acid receptor
To Be Published
2QPT
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Crystal structure of an EHD ATPase involved in membrane remodelling
分子名称: CALCIUM ION, EH DOMAIN-CONTAINING PROTEIN-2, MAGNESIUM ION, ...
著者Daumke, O.
登録日2007-07-25
公開日2007-10-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Architectural and mechanistic insights into an EHD ATPase involved in membrane remodelling.
Nature, 449, 2007
2R09
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BU of 2r09 by Molmil
Crystal Structure of Autoinhibited Form of Grp1 Arf GTPase Exchange Factor
分子名称: 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Cytohesin-3, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, ...
著者DiNitto, J.P, Delprato, A, Gabe Lee, M.T, Cronin, T.C, Huang, S, Guilherme, A, Czech, M.P, Lambright, D.G.
登録日2007-08-17
公開日2007-12-04
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Basis and Mechanism of Autoregulation in 3-Phosphoinositide-Dependent Grp1 Family Arf GTPase Exchange Factors.
Mol.Cell, 28, 2007
2QAG
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Crystal structure of human septin trimer 2/6/7
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Septin-2, ...
著者Sirajuddin, M.
登録日2007-06-15
公開日2007-08-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structural insight into filament formation by mammalian septins.
Nature, 449, 2007
4F7G
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Crystal structure of talin autoinhibition complex
分子名称: Talin-1
著者Song, X, Qin, J, Ye, S, Zhang, R.
登録日2012-05-16
公開日2012-07-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesion.
Cell Res., 22, 2012

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