PDB: 8861 件ウェブページステータス検索Chemie searchBIRD

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3MRH	Crystal Structure of MHC class I HLA-A2 molecule complexed with HCV NS3-1073-1081 nonapeptide N3S variant 分子名称: 9-meric peptide from Serine protease/NTPase/helicase NS3, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... 著者 Gras, S, Reiser, J.-B, Chouquet, A, Le Gorrec, M, Debeaupuis, E, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D. 登録日 2010-04-29 公開日 2011-05-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Analysis of Relationships between Peptide/MHC Structural Features and Naive T Cell Frequency in Humans. J.Immunol., 193, 2014
6ZD1	Structure of apo telomerase from Candida Tropicalis 分子名称: Telomerase reverse transcriptase 著者 Zhai, L, Rety, S, Chen, W.F, Auguin, D, Xi, X.G. 登録日 2020-06-13 公開日 2021-04-28 最終更新日 2021-05-12 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 Crystal structures of N-terminally truncated telomerase reverse transcriptase from fungi‡. Nucleic Acids Res., 49, 2021
6ZD6	Structure of apo telomerase from Candida Tropicalis 分子名称: Telomerase reverse transcriptase 著者 Zhai, L, Rety, S, Chen, W.F, Auguin, D, Xi, X.G. 登録日 2020-06-13 公開日 2021-04-28 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Crystal structures of N-terminally truncated telomerase reverse transcriptase from fungi‡. Nucleic Acids Res., 49, 2021
1A1R	HCV NS3 PROTEASE DOMAIN:NS4A PEPTIDE COMPLEX 分子名称: NS3 PROTEIN, NS4A PROTEIN, ZINC ION 著者 Kim, J.L, Morgenstern, K.A, Lin, C, Fox, T, Dwyer, M.D, Landro, J.A, Chambers, S.P, Markland, W, Lepre, C.A, O'Malley, E.T, Harbeson, S.L, Rice, C.M, Murcko, M.A, Caron, P.R, Thomson, J.A. 登録日 1997-12-15 公開日 1998-06-17 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide. Cell(Cambridge,Mass.), 87, 1996
7U1A	RFC:PCNA bound to dsDNA with a ssDNA gap of six nucleotides 分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA - Primer, DNA - Template, ... 著者 Liu, X, Gaubitz, C, Pajak, J, Kelch, B.A. 登録日 2022-02-20 公開日 2022-07-06 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 A second DNA binding site on RFC facilitates clamp loading at gapped or nicked DNA. Elife, 11, 2022
7U1P	RFC:PCNA bound to DNA with a ssDNA gap of five nucleotides 分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA - Primer, DNA - Template, ... 著者 Liu, X, Gaubitz, C, Pajak, J, Kelch, B.A. 登録日 2022-02-21 公開日 2022-07-06 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 A second DNA binding site on RFC facilitates clamp loading at gapped or nicked DNA. Elife, 11, 2022
1T03	HIV-1 reverse transcriptase crosslinked to tenofovir terminated template-primer (complex P) 分子名称: MAGNESIUM ION, POL polyprotein, Synthetic oligonucleotide primer, ... 著者 Tuske, S, Sarafianos, S.G, Ding, J, Arnold, E. 登録日 2004-04-07 公開日 2004-05-11 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure of HIV-1 RT-DNA complexes before and after incorporation of the anti-AIDS drug tenofovir Nat.Struct.Mol.Biol., 11, 2004
1T05	HIV-1 reverse transcriptase crosslinked to template-primer with tenofovir-diphosphate bound as the incoming nucleotide substrate 分子名称: GLYCEROL, MAGNESIUM ION, POL polyprotein, ... 著者 Tuske, S, Sarafianos, S.G, Ding, J, Arnold, E. 登録日 2004-04-07 公開日 2004-05-11 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structures of HIV-1 RT-DNA complexes before and after incorporation of the anti-AIDS drug tenofovir Nat.Struct.Mol.Biol., 11, 2004
2YMN	Organization of the Influenza Virus Replication Machinery 分子名称: NUCLEOPROTEIN 著者 Moeller, A, Kirchdoerfer, R.N, Potter, C.S, Carragher, B, Wilson, I.A. 登録日 2012-10-09 公開日 2012-12-05 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (20 Å) 主引用文献 Organization of the Influenza Virus Replication Machinery. Science, 338, 2012
5T1V	Crystal structure of Zika virus NS2B-NS3 protease in apo-form. 分子名称: NS2B-NS3 protease,NS2B-NS3 protease 著者 Nocadello, S, Light, S.H, Minasov, G, Shuvalova, L, Cardona-Correa, A.A, Ojeda, I, Vargas, J, Johnson, M.E, Lee, H, Anderson, W.F, Center for Structural Genomics of Infectious Diseases, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2016-08-22 公開日 2016-09-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal structure of Zika virus NS2B-NS3 protease in apo-form. To Be Published
2CLZ	Mhc Class I Natural Mutant H-2Kbm8 Heavy Chain Complexed With beta-2 Microglobulin and pBM1 peptide 分子名称: BETA-2 MICROGLOBULIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, K-B ALPHA CHAIN, ... 著者 Mazza, C, Auphan-Anezin, N, Guimezanes, A, Barrett-Wilt, G.A, Montero-Julian, F, Roussel, A, Hunt, D.F, Schmitt-Verhulst, A.M, Malissen, B. 登録日 2006-05-03 公開日 2006-06-14 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Distinct Orientation of the Alloreactive Monoclonal Cd8 T Cell Activation Program by Three Different Peptide/Mhc Complexes. Eur.J.Immunol., 36, 2006
7LUN	Human PARP14 (ARTD8), catalytic fragment in complex with RBN011980 分子名称: 7-(cyclopentylamino)-5-fluoro-2-{[(trans-4-hydroxycyclohexyl)sulfanyl]methyl}quinazolin-4(3H)-one, CHLORIDE ION, GLYCEROL, ... 著者 Dorsey, B.W, Swinger, K.K, Schenkel, L.B, Church, W.D, Perl, N.R, Vasbinder, M.M, Wigle, T.J, Kuntz, K.W. 登録日 2021-02-22 公開日 2021-04-21 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Targeted Degradation of PARP14 Using a Heterobifunctional Small Molecule. Chembiochem, 22, 2021
1TL3	Crystal structure of hiv-1 reverse transcriptase in complex with gw450557 分子名称: 6-CHLORO-4-(CYCLOHEXYLOXY)-3-ISOPROPYLQUINOLIN-2(1H)-ONE, PHOSPHATE ION, Pol polyprotein, ... 著者 Hopkins, A.L, Ren, J, Stuart, D.I, Stammers, D.K. 登録日 2004-06-09 公開日 2004-12-07 最終更新日 2022-12-21 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1. J.Med.Chem., 47, 2004
1OK8	Crystal structure of the dengue 2 virus envelope glycoprotein in the postfusion conformation 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, MAJOR ENVELOPE PROTEIN E 著者 Modis, Y, Harrison, S.C. 登録日 2003-07-19 公開日 2004-01-29 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of the Dengue Virus Envelope Protein After Membrane Fusion Nature, 427, 2004
1TKT	CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH GW426318 分子名称: 6-CHLORO-4-(CYCLOHEXYLOXY)-3-PROPYLQUINOLIN-2(1H)-ONE, MAGNESIUM ION, PHOSPHATE ION, ... 著者 Hopkins, A.L, Ren, J, Stuart, D.I, Stammers, D.K. 登録日 2004-06-09 公開日 2004-12-07 最終更新日 2018-01-31 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1. J.Med.Chem., 47, 2004
1TL1	CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH GW451211 分子名称: 6-CHLORO-4-(CYCLOHEXYLSULFINYL)-3-PROPYLQUINOLIN-2(1H)-ONE, PHOSPHATE ION, Pol polyprotein, ... 著者 Hopkins, A.L, Ren, J, Stuart, D.I, Stammers, D.K. 登録日 2004-06-09 公開日 2004-12-07 最終更新日 2022-12-21 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1. J.Med.Chem., 47, 2004
1DY9	Inhibition of the Hepatitis C Virus NS3/4A Protease. The Crystal Structures of Two Protease-Inhibitor Complexes (inhibitor I) 分子名称: N-(tert-butoxycarbonyl)-L-alpha-glutamyl-N-[(1R)-1-(carboxycarbonyl)-3,3-difluoropropyl]-L-leucinamide, NONSTRUCTURAL PROTEIN NS4A (P4), PROTEASE/HELICASE NS3 (P70), ... 著者 Di Marco, S, Rizzi, M, Volpari, C, Walsh, M, Narjes, F, Colarusso, S, De Francesco, R, Matassa, V.G, Sollazzo, M. 登録日 2000-01-31 公開日 2001-01-28 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Inhibition of the Hepatitis C Virus Ns3/4A Protease the Crystal Structures of Two Protease-Inhibitor Complexes J.Biol.Chem., 275, 2000
4F7M	Crystal Structure of HLA-A*2402 Complexed with a Newly Identified Peptide from 2009 H1N1 PA (649-658) 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ... 著者 Liu, J, Zhang, S, Tan, S, Yi, Y, Wu, B, Zhu, F, Wang, H, Qi, J, George, F.G. 登録日 2012-05-16 公開日 2012-10-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Cross-Allele Cytotoxic T Lymphocyte Responses against 2009 Pandemic H1N1 Influenza A Virus among HLA-A24 and HLA-A3 Supertype-Positive Individuals. J.Virol., 86, 2012
1HBW	Solution nmr structure of the dimerization domain of the yeast transcriptional activator Gal4 (residues 50-106) 分子名称: REGULATORY PROTEIN GAL4 著者 Hidalgo, P, Ansari, A.Z, Schmidt, P, Hare, B, Simkovic, N, Farrell, S, Shin, E.J, Ptashne, M, Wagner, G. 登録日 2001-04-20 公開日 2001-05-10 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Recruitment of the Transcriptional Machinery Through Gal11P: Structure and Interactions of the GAL4 Dimerization Domain Genes Dev., 15, 2001
7U19	RFC:PCNA bound to nicked DNA 分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA, MAGNESIUM ION, ... 著者 Liu, X, Gaubitz, C, Pajak, J, Kelch, B.A. 登録日 2022-02-20 公開日 2022-07-06 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 A second DNA binding site on RFC facilitates clamp loading at gapped or nicked DNA. Elife, 11, 2022
1JXP	BK STRAIN HEPATITIS C VIRUS (HCV) NS3-NS4A 分子名称: NS3 SERINE PROTEASE, NS4A, ZINC ION 著者 Yan, Y, Munshi, S, Chen, Z. 登録日 1997-08-21 公開日 1998-01-14 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Complex of NS3 protease and NS4A peptide of BK strain hepatitis C virus: a 2.2 A resolution structure in a hexagonal crystal form. Protein Sci., 7, 1998
8FS5	Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 3 (open 9-1-1 and stably bound chamber DNA) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DDC1 isoform 1, ... 著者 Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. 登録日 2023-01-09 公開日 2023-06-14 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.76 Å) 主引用文献 Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology. Biorxiv, 2023
8FS8	Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 5-nt gapped DNA (9-1-1 encircling fully bound DNA) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DDC1 isoform 1, ... 著者 Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. 登録日 2023-01-09 公開日 2023-06-14 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.04 Å) 主引用文献 Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology. Biorxiv, 2023
8FS7	Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 5 (closed 9-1-1 and stably bound chamber DNA) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DDC1 isoform 1, ... 著者 Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. 登録日 2023-01-09 公開日 2023-06-14 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.85 Å) 主引用文献 Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology. Biorxiv, 2023
8FS6	Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 4 (partially closed 9-1-1 and stably bound chamber DNA) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DDC1 isoform 1, ... 著者 Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. 登録日 2023-01-09 公開日 2023-06-14 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology. Biorxiv, 2023

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