5J2Q
| HIV-1 reverse transcriptase in complex with DNA that has incorporated a mismatched EFdA-MP at the N-(pre-translocation) site | 分子名称: | 2'-deoxy-4'-ethynyl-2-fluoroadenosine 5'-(dihydrogen phosphate), DNA (27-MER), DNA (5'-D(*AP*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*(6FM)P*(6FM))-3'), ... | 著者 | Salie, Z.L, Kirby, K.A, Sarafianos, S.G. | 登録日 | 2016-03-29 | 公開日 | 2016-08-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.789 Å) | 主引用文献 | Structural basis of HIV inhibition by translocation-defective RT inhibitor 4'-ethynyl-2-fluoro-2'-deoxyadenosine (EFdA). Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
6LUA
| |
6LUF
| |
5J2M
| HIV-1 reverse transcriptase in complex with DNA and EFdA-triphosphate, a translocation-defective RT inhibitor | 分子名称: | 2'-deoxy-4'-ethynyl-2-fluoroadenosine 5'-(tetrahydrogen triphosphate), DNA (27-MER), DNA (5'-D(*AP*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*G)-3'), ... | 著者 | Salie, Z.L, Kirby, K.A, Sarafianos, S.G. | 登録日 | 2016-03-29 | 公開日 | 2016-08-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.432 Å) | 主引用文献 | Structural basis of HIV inhibition by translocation-defective RT inhibitor 4'-ethynyl-2-fluoro-2'-deoxyadenosine (EFdA). Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
5J2P
| HIV-1 reverse transcriptase in complex with DNA that has incorporated EFdA-MP at the P-(post-translocation) site and a second EFdA-MP at the N-(pre-translocation) site | 分子名称: | 2'-deoxy-4'-ethynyl-2-fluoroadenosine 5'-(dihydrogen phosphate), DNA (27-MER), DNA (5'-D(*AP*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*(6FM)P*(6FM))-3'), ... | 著者 | Salie, Z.L, Kirby, K.A, Sarafianos, S.G. | 登録日 | 2016-03-29 | 公開日 | 2016-08-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Structural basis of HIV inhibition by translocation-defective RT inhibitor 4'-ethynyl-2-fluoro-2'-deoxyadenosine (EFdA). Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
5TW3
| Crystal Structure of HIV-1 Reverse Transcriptase in Complex with 5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)-4-fluorophenoxy)-7-fluoro-2-naphthonitrile (JLJ636), a Non-nucleoside Inhibitor | 分子名称: | 5-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]-4-fluorophenoxy}-7-fluoronaphthalene-2-carbonitrile, HIV-1 REVERSE TRANSCRIPTASE, P51 SUBUNIT, ... | 著者 | Chan, A.H, Anderson, K.S. | 登録日 | 2016-11-11 | 公開日 | 2017-03-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.853 Å) | 主引用文献 | Structural and Preclinical Studies of Computationally Designed Non-Nucleoside Reverse Transcriptase Inhibitors for Treating HIV infection. Mol. Pharmacol., 91, 2017
|
|
6X0N
| |
6UPL
| Structure of FACT_subnucleosome complex 2 | 分子名称: | DNA (79-mer), FACT complex subunit SPT16, FACT complex subunit SSRP1, ... | 著者 | Zhou, K, Tan, Y.Z, Wei, H, Liu, Y, Carragher, B, Potter, C, Luger, K. | 登録日 | 2019-10-17 | 公開日 | 2019-12-11 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (7.4 Å) | 主引用文献 | FACT caught in the act of manipulating the nucleosome. Nature, 577, 2020
|
|
6UPK
| Structure of FACT_subnucleosome complex 1 | 分子名称: | DNA (79-mer), FACT complex subunit SPT16, FACT complex subunit SSRP1, ... | 著者 | Zhou, K, Tan, Y.Z, Wei, H, Liu, Y, Carragher, B, Potter, C, Luger, K. | 登録日 | 2019-10-17 | 公開日 | 2019-12-11 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | FACT caught in the act of manipulating the nucleosome. Nature, 577, 2020
|
|
4UIH
| Cryo-EM structure of Dengue virus serotype 2 strain New Guinea-C complexed with human antibody 2D22 Fab at 37 degree C. The Fab molecules were added to the virus before 37 degree C incubation. | 分子名称: | ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 -HEAVY CHAIN, ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 -LIGHT CHAIN, DENGUE VIRUS SEROTYPE 2 STRAIN NEW GUINEA-C E PROTEIN ECTODOMAIN | 著者 | Fibriansah, G, Ibarra, K.D, Ng, T.-S, Smith, S.A, Tan, J.L, Lim, X.N, Ooi, J.S.G, Kostyuchenko, V.A, Wang, J, de Silva, A.M, Harris, E, Crowe, J.E, Lok, S.-M. | 登録日 | 2015-03-30 | 公開日 | 2015-07-15 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (20 Å) | 主引用文献 | Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers. Science, 349, 2015
|
|
8VAR
| |
8VAL
| |
8VAQ
| |
8VAS
| |
6K3L
| Crystal structure of CX-4945 bound Cka1 from C. neoformans | 分子名称: | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, CMGC/CK2 protein kinase, SULFATE ION | 著者 | Cho, H.S, Yoo, Y. | 登録日 | 2019-05-20 | 公開日 | 2019-11-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Structural analysis of fungal pathogenicity-related casein kinase alpha subunit, Cka1, in the human fungal pathogen Cryptococcus neoformans. Sci Rep, 9, 2019
|
|
6KO6
| Crystal structure of AMPPNP bound Cka1 from C. neoformans | 分子名称: | CMGC/CK2 protein kinase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Cho, H.S, Yoo, Y. | 登録日 | 2019-08-08 | 公開日 | 2019-11-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural analysis of fungal pathogenicity-related casein kinase alpha subunit, Cka1, in the human fungal pathogen Cryptococcus neoformans. Sci Rep, 9, 2019
|
|
7JLT
| |
7MC9
| X-RAY STRUCTURE OF PEDV PAPAIN-LIKE PROTEASE 2 bound to UB-PA | 分子名称: | 3C-like proteinase, Ubiquitin, ZINC ION, ... | 著者 | Durie, I.A, Dzimianski, J.V, Daczkowski, C.M, Pegan, S.D. | 登録日 | 2021-04-01 | 公開日 | 2021-07-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.099 Å) | 主引用文献 | Structural insights into the interaction of papain-like protease 2 from the alphacoronavirus porcine epidemic diarrhea virus and ubiquitin Acta Cryst. D, 77, 2021
|
|
8G2Z
| 48-nm doublet microtubule from Tetrahymena thermophila strain CU428 | 分子名称: | B2B3_fMIP, B5B6_fMIP, CFAM166A, ... | 著者 | Black, C.S, Kubo, S, Yang, S.K, Bui, K.H. | 登録日 | 2023-02-06 | 公開日 | 2023-06-14 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Native doublet microtubules from Tetrahymena thermophila reveal the importance of outer junction proteins. Nat Commun, 14, 2023
|
|
8G3D
| 48-nm doublet microtubule from Tetrahymena thermophila strain K40R | 分子名称: | B2B3_fMIP, B5B6_fMIP, CFAM166A, ... | 著者 | Black, C.S, Kubo, S, Yang, S.K, Bui, K.H. | 登録日 | 2023-02-07 | 公開日 | 2023-06-14 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Native doublet microtubules from Tetrahymena thermophila reveal the importance of outer junction proteins. Nat Commun, 14, 2023
|
|
3MRL
| Crystal Structure of MHC class I HLA-A2 molecule complexed with HCV NS3-1073-1081 nonapeptide C6V variant | 分子名称: | 9-meric peptide from Serine protease/NTPase/helicase NS3, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Gras, S, Reiser, J.-B, Chouquet, A, Le Gorrec, M, Debeaupuis, E, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D. | 登録日 | 2010-04-29 | 公開日 | 2011-05-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Analysis of Relationships between Peptide/MHC Structural Features and Naive T Cell Frequency in Humans. J.Immunol., 193, 2014
|
|
3MRJ
| Crystal Structure of MHC class I HLA-A2 molecule complexed with HCV NS3-1073-1081 nonapeptide V5M variant | 分子名称: | 9-meric peptide from Serine protease/NTPase/helicase NS3, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Reiser, J.-B, Le Gorrec, M, Chouquet, A, Debeaupuis, E, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D. | 登録日 | 2010-04-29 | 公開日 | 2011-05-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Crystal Structure of MHC class I HLA-A2 molecule complexed with HCV NS3-1073-1081 nonapeptide V5M variant To be Published
|
|
1TKZ
| CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH GW429576 | 分子名称: | 6-CHLORO-4-(CYCLOHEXYLSULFANYL)-3-PROPYLQUINOLIN-2(1H)-ONE, PHOSPHATE ION, Pol polyprotein, ... | 著者 | Hopkins, A.L, Ren, J, Stuart, D.I, Stammers, D.K. | 登録日 | 2004-06-09 | 公開日 | 2004-12-07 | 最終更新日 | 2020-01-15 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1. J.Med.Chem., 47, 2004
|
|
3MRI
| Crystal Structure of MHC class I HLA-A2 molecule complexed with HCV NS3-1073-1081 nonapeptide G4M-V5W variant | 分子名称: | 9-meric peptide from Serine protease/NTPase/helicase NS3, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Reiser, J.-B, Le Gorrec, M, Chouquet, A, Debeaupuis, E, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D. | 登録日 | 2010-04-29 | 公開日 | 2011-05-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure of MHC class I HLA-A2 molecule complexed with HCV NS3-1073-1081 nonapeptide G4M-V5W variant To be Published
|
|
3MRG
| Crystal Structure of MHC class I HLA-A2 molecule complexed with HCV NS3-1073-1081 nonapeptide | 分子名称: | 9-meric peptide from Serine protease/NTPase/helicase NS3, Beta-2-microglobulin, CITRIC ACID, ... | 著者 | Gras, S, Reiser, J.-B, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D. | 登録日 | 2010-04-29 | 公開日 | 2011-05-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Analysis of Relationships between Peptide/MHC Structural Features and Naive T Cell Frequency in Humans. J.Immunol., 193, 2014
|
|