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1W98
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The structural basis of CDK2 activation by cyclin E
分子名称: CELL DIVISION PROTEIN KINASE 2, G1/S-SPECIFIC CYCLIN E1
著者Lowe, E.D, Honda, R, Dubinina, E, Skamnaki, V, Cook, A, Johnson, L.N.
登録日2004-10-07
公開日2005-02-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The Structure of Cyclin E1/Cdk2: Implications for Cdk2 Activation and Cdk2-Independent Roles
Embo J., 24, 2005
7ZLV
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Tail tip of siphophage T5 : central fibre protein pb4
分子名称: Probable central straight fiber
著者Linares, R, Arnaud, C.A, Effantin, G, Epalle, N, Boeri Erba, E, Schoehn, G, Breyton, C.
登録日2022-04-15
公開日2023-02-08
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (4.22 Å)
主引用文献Structural basis of bacteriophage T5 infection trigger and E. coli cell wall perforation.
Sci Adv, 9, 2023
1U1G
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Structure of E. coli uridine phosphorylase complexed to 5-(m-(benzyloxy)benzyl)barbituric acid (BBBA)
分子名称: 1-((2-HYDROXYETHOXY)METHYL)-5-(3-(BENZYLOXY)BENZYL)-6-HYDROXYPYRIMIDINE-2,4(1H,3H)-DIONE, POTASSIUM ION, Uridine phosphorylase
著者Bu, W, Settembre, E.C, Ealick, S.E.
登録日2004-07-15
公開日2005-07-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis for inhibition of Escherichia coli uridine phosphorylase by 5-substituted acyclouridines.
Acta Crystallogr.,Sect.D, 61, 2005
1LWF
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CRYSTAL STRUCTURE OF A MUTANT HIV-1 REVERSE TRANSCRIPTASE (RTMQ+M184V: M41L/D67N/K70R/M184V/T215Y) IN COMPLEX WITH NEVIRAPINE
分子名称: 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, HIV-1 REVERSE TRANSCRIPTASE
著者Ren, J, Chamberlain, P.P, Nichols, C.E, Douglas, L, Stuart, D.I, Stammers, D.K.
登録日2002-05-31
公開日2002-10-30
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of Zidovudine- or Lamivudine-resistant human immunodeficiency virus type 1 reverse transcriptases containing mutations at codons 41, 184, and 215.
J.Virol., 76, 2002
1LW0
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CRYSTAL STRUCTURE OF T215Y MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH NEVIRAPINE
分子名称: 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, HIV-1 REVERSE TRANSCRIPTASE, PHOSPHATE ION
著者Ren, J, Chamberlain, P.P, Nichols, C.E, Douglas, L, Stuart, D.I, Stammers, D.K.
登録日2002-05-30
公開日2002-10-30
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of Zidovudine- or Lamivudine-resistant human immunodeficiency virus type 1 reverse transcriptases containing mutations at codons 41, 184, and 215.
J.Virol., 76, 2002
2OML
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crystal structure of E. coli pseudouridine synthase RluE
分子名称: Ribosomal large subunit pseudouridine synthase E, SULFATE ION
著者Pan, H, Ho, J.D, Stroud, R.M, Finer-Moore, J.
登録日2007-01-22
公開日2007-03-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献The Crystal Structure of E. coli rRNA Pseudouridine Synthase RluE.
J.Mol.Biol., 367, 2007
2OLW
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Crystal Structure of E. coli pseudouridine synthase RluE
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ACETIC ACID, Ribosomal large subunit pseudouridine synthase E, ...
著者Pan, H, Ho, J.D, Stroud, R.M, Finer-Moore, J.
登録日2007-01-19
公開日2007-03-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The Crystal Structure of E. coli rRNA Pseudouridine Synthase RluE.
J.Mol.Biol., 367, 2007
5CYM
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HIV-1 reverse transcriptase complexed with 4-iodopyrazole
分子名称: 1,2-ETHANEDIOL, 4-IODOPYRAZOLE, 4-{[4-({4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile, ...
著者Bauman, J.D, Arnold, E.
登録日2015-07-30
公開日2015-12-30
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Rapid experimental SAD phasing and hot spot identification with halogenated fragments
Iucrj, 3, 2016
1U1D
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Structure of e. coli uridine phosphorylase complexed to 5-(phenylthio)acyclouridine (ptau)
分子名称: 1-((2-HYDROXYETHOXY)METHYL)-5-(PHENYLTHIO)PYRIMIDINE-2,4(1H,3H)-DIONE, PHOSPHATE ION, POTASSIUM ION, ...
著者Bu, W, Settembre, E.C, Ealick, S.E.
登録日2004-07-15
公開日2005-07-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Structural basis for inhibition of Escherichia coli uridine phosphorylase by 5-substituted acyclouridines.
Acta Crystallogr.,Sect.D, 61, 2005
1T4R
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arginase-descarboxy-nor-NOHA complex
分子名称: 3-{[(E)-AMINO(HYDROXYIMINO)METHYL]AMINO}PROPAN-1-AMINIUM, Arginase 1, MANGANESE (II) ION
著者Cama, E, Pethe, S, Boucher, J.-L, Shoufa, H, Emig, F.A, Ash, D.E, Viola, R.E, Mansuy, D, Christianson, D.W.
登録日2004-04-30
公開日2005-04-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Inhibitor coordination interactions in the binuclear manganese cluster of arginase
Biochemistry, 43, 2004
1U1E
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Structure of e. coli uridine phosphorylase complexed to 5(phenylseleno)acyclouridine (PSAU)
分子名称: 1-((2-HYDROXYETHOXY)METHYL)-5-(PHENYLSELANYL)PYRIMIDINE-2,4(1H,3H)-DIONE, PHOSPHATE ION, POTASSIUM ION, ...
著者Bu, W, Settembre, E.C, Ealick, S.E.
登録日2004-07-15
公開日2005-07-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Structural basis for inhibition of Escherichia coli uridine phosphorylase by 5-substituted acyclouridines.
Acta Crystallogr.,Sect.D, 61, 2005
1U1C
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Structure of E. coli uridine phosphorylase complexed to 5-benzylacyclouridine (BAU)
分子名称: 1-((2-HYDROXYETHOXY)METHYL)-5-BENZYLPYRIMIDINE-2,4(1H,3H)-DIONE, PHOSPHATE ION, POTASSIUM ION, ...
著者Bu, W, Settembre, E.C, Ealick, S.E.
登録日2004-07-15
公開日2005-07-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for inhibition of Escherichia coli uridine phosphorylase by 5-substituted acyclouridines.
Acta Crystallogr.,Sect.D, 61, 2005
1U1F
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Structure of e. coli uridine phosphorylase complexed to 5-(m-(benzyloxy)benzyl)acyclouridine (BBAU)
分子名称: 1-((2-HYDROXYETHOXY)METHYL)-5-(3-(BENZYLOXY)BENZYL)PYRIMIDINE-2,4(1H,3H)-DIONE, PHOSPHATE ION, POTASSIUM ION, ...
著者Bu, W, Settembre, E.C, Ealick, S.E.
登録日2004-07-15
公開日2005-07-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for inhibition of Escherichia coli uridine phosphorylase by 5-substituted acyclouridines.
Acta Crystallogr.,Sect.D, 61, 2005
1LWE
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BU of 1lwe by Molmil
CRYSTAL STRUCTURE OF M41L/T215Y MUTANT HIV-1 REVERSE TRANSCRIPTASE (RTMN) IN COMPLEX WITH NEVIRAPINE
分子名称: 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, HIV-1 REVERSE TRANSCRIPTASE, PHOSPHATE ION
著者Ren, J, Chamberlain, P.P, Nichols, C.E, Douglas, L, Stuart, D.I, Stammers, D.K.
登録日2002-05-31
公開日2002-10-30
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Crystal structures of Zidovudine- or Lamivudine-resistant human immunodeficiency virus type 1 reverse transcriptases containing mutations at codons 41, 184, and 215.
J.Virol., 76, 2002
1T5C
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Crystal structure of the motor domain of human kinetochore protein CENP-E
分子名称: ADENOSINE-5'-DIPHOSPHATE, Centromeric protein E, MAGNESIUM ION, ...
著者Garcia-Saez, I, Yen, T, Wade, R.H, Kozielski, F, Structural Proteomics in Europe (SPINE)
登録日2004-05-04
公開日2005-05-10
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the motor domain of the human kinetochore protein CENP-E.
J.Mol.Biol., 340, 2004
1ZKX
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Crystal structure of Glu158Ala/Thr159Ala/Asn160Ala- a triple mutant of Clostridium botulinum neurotoxin E catalytic domain
分子名称: CHLORIDE ION, ZINC ION, botulinum neurotoxin type E
著者Agarwal, R, Binz, T, Swaminathan, S.
登録日2005-05-04
公開日2005-07-05
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Analysis of Active Site Residues of Botulinum Neurotoxin E by Mutational, Functional, and Structural Studies: Glu335Gln Is an Apoenzyme.
Biochemistry, 44, 2005
1LLR
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CHOLERA TOXIN B-PENTAMER WITH LIGAND BMSC-0012
分子名称: 3-AMINO-4-{3-[2-(2-PROPOXY-ETHOXY)-ETHOXY]-PROPYLAMINO}-CYCLOBUT-3-ENE-1,2-DIONE, 5-aminocarbonyl-3-nitrophenyl alpha-D-galactopyranoside, CHOLERA TOXIN B SUBUNIT
著者Merritt, E.A, Hol, W.G.J.
登録日2002-04-30
公開日2002-08-14
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Characterization and crystal structure of a high-affinity pentavalent receptor-binding inhibitor for cholera toxin and E. coli heat-labile enterotoxin.
J.Am.Chem.Soc., 124, 2002
1ZL6
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Crystal structure of Tyr350Ala mutant of Clostridium botulinum neurotoxin E catalytic domain
分子名称: SULFATE ION, ZINC ION, botulinum neurotoxin type E
著者Agarwal, R, Binz, T, Swaminathan, S.
登録日2005-05-05
公開日2005-06-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Analysis of Active Site Residues of Botulinum Neurotoxin E by Mutational, Functional, and Structural Studies: Glu335Gln Is an Apoenzyme.
Biochemistry, 44, 2005
1ZN3
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BU of 1zn3 by Molmil
Crystal structure of Glu335Ala mutant of Clostridium botulinum neurotoxin type E
分子名称: CHLORIDE ION, ZINC ION, botulinum neurotoxin type E
著者Agarwal, R, Binz, T, Swaminathan, S.
登録日2005-05-11
公開日2005-07-05
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Analysis of Active Site Residues of Botulinum Neurotoxin E by Mutational, Functional, and Structural Studies: Glu335Gln Is an Apoenzyme.
Biochemistry, 44, 2005
1ZKW
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Crystal structure of Arg347Ala mutant of botulinum neurotoxin E catalytic domain
分子名称: CHLORIDE ION, ZINC ION, botulinum neurotoxin type E
著者Agarwal, R, Binz, T, Swaminathan, S.
登録日2005-05-04
公開日2005-06-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Analysis of Active Site Residues of Botulinum Neurotoxin E by Mutational, Functional, and Structural Studies: Glu335Gln Is an Apoenzyme.
Biochemistry, 44, 2005
1ZL5
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Crystal structure of Glu335Gln mutant of Clostridium botulinum neurotoxin E catalytic domain
分子名称: CHLORIDE ION, botulinum neurotoxin type E
著者Agarwal, R, Binz, T, Swaminathan, S.
登録日2005-05-05
公開日2005-07-05
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Analysis of Active Site Residues of Botulinum Neurotoxin E by Mutational, Functional, and Structural Studies: Glu335Gln Is an Apoenzyme.
Biochemistry, 44, 2005
5CC9
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L28F E.coli dihydrofolate reductase complexed with 5,10-dideazatetrahydrofolate and oxidized nicotinamide adenine dinucleotide phosphate
分子名称: 5,10-DIDEAZATETRAHYDROFOLIC ACID, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Oyen, D, Wright, P.E.
登録日2015-07-01
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.199 Å)
主引用文献Cofactor-Mediated Conformational Dynamics Promote Product Release From Escherichia coli Dihydrofolate Reductase via an Allosteric Pathway.
J.Am.Chem.Soc., 137, 2015
7L2A
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Molybdopterin cofactor biosynthesis protein E from Burkholderia multivorans ATCC 17616
分子名称: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, IMIDAZOLE, ...
著者Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2020-12-16
公開日2020-12-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Molybdopterin cofactor biosynthesis protein E from Burkholderia multivorans ATCC 17616
to be published
1QCZ
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CRYSTAL STRUCTURE OF E. COLI PURE, AN UNUSUAL MUTASE THAT CATALYZES THE CONVERSION OF N5-CARBOXYAMINOIMIDAZOLE RIBONUCLEOTIDE (N5-CAIR) TO 4-CARBOXYAMINOIMIDAZOLE RIBONUCLEOTIDE (CAIR) IN THE PURINE BIOSYNTHETIC PATHWAY
分子名称: N5-CARBOXYAMINOIMIDAZOLE RIBONUCLEOTIDE MUTASE
著者Ealick, S.E, Mathews, I.I.
登録日1999-05-10
公開日1999-11-10
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of Escherichia coli PurE, an unusual mutase in the purine biosynthetic pathway.
Structure Fold.Des., 7, 1999
7BAQ
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Crystal structure of the cAMP-dependent protein kinase A cocrystallized with a chiral ligand (S- and E-configuration) and PKI (5-24)
分子名称: (S,E)-3-(2-(3-bromo-4-hydroxybenzylidene)hydrazineyl)-2-(3-chlorophenyl)-3-oxopropan-1-aminium, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha
著者Oebbeke, M, Heine, A, Klebe, G.
登録日2020-12-16
公開日2022-01-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Crystal structure of the cAMP-dependent protein kinase A cocrystallized with a chiral ligand (S- and E-configuration) and PKI (5-24)
To Be Published

223532

件を2024-08-07に公開中

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