6QDV
 
 | | Human post-catalytic P complex spliceosome | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | | 著者 | Fica, S.M, Oubridge, C, Wilkinson, M.E, Newman, A.J, Nagai, K. | | 登録日 | 2019-01-03 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | A human postcatalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation.
Science, 363, 2019
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7OW7
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6QI9
 | | Truncated human R2TP complex, structure 4 (ADP-empty) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2 | | 著者 | Munoz-Hernandez, H, Rodriguez, C.F, Llorca, O. | | 登録日 | 2019-01-18 | | 公開日 | 2019-05-15 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.63 Å) | | 主引用文献 | Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM.
Sci Adv, 5, 2019
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3G73
 | | Structure of the FOXM1 DNA binding | | 分子名称: | DNA (5'-D(P*AP*AP*AP*TP*TP*GP*TP*TP*TP*AP*TP*AP*AP*AP*CP*AP*GP*CP*CP*CP*G)-3'), DNA (5'-D(P*TP*TP*CP*GP*GP*GP*CP*TP*GP*TP*TP*TP*AP*TP*AP*AP*AP*CP*AP*AP*T)-3'), Forkhead box protein M1, ... | | 著者 | Littler, D.R, Perrakis, A, Hibbert, R.G, Medema, R.H. | | 登録日 | 2009-02-09 | | 公開日 | 2009-03-03 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Structure of the FoxM1 DNA-recognition domain bound to a promoter sequence
Nucleic Acids Res., 2010
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6QI8
 | | Truncated human R2TP complex, structure 3 (ADP-filled) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2 | | 著者 | Munoz-Hernandez, H, Rodriguez, C.F, Llorca, O. | | 登録日 | 2019-01-18 | | 公開日 | 2019-04-10 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | | 主引用文献 | Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM.
Sci Adv, 5, 2019
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3G2G
 | | S437Y Mutant of human muscle pyruvate kinase, isoform M2 | | 分子名称: | Pyruvate kinase isozymes M1/M2, SULFATE ION, UNKNOWN ATOM OR ION | | 著者 | Hong, B, Dimov, S, Allali-Hassani, A, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, c, Weigelt, J, Bochkarev, A, Vedadi, M, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2009-01-31 | | 公開日 | 2009-03-03 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | S437Y Mutant of human muscle pyruvate kinase, isoform M2
To be Published
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3G1E
 | | X-ray crystal structure of coil 1A of human vimentin | | 分子名称: | Vimentin | | 著者 | Meier, M, Padilla, G.P, Herrmann, H, Wedig, T, Hergt, M, Patel, T.R, Stetefeld, J, Aebi, U, Burkhard, P. | | 登録日 | 2009-01-29 | | 公開日 | 2009-05-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Vimentin coil 1A-A molecular switch involved in the initiation of filament elongation.
J.Mol.Biol., 390, 2009
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3GEF
 | | Crystal structure of the R482W mutant of lamin A/C | | 分子名称: | Lamin-A/C | | 著者 | Magracheva, E, Kozlov, S, Stuart, C, Wlodawer, A, Zdanov, A. | | 登録日 | 2009-02-25 | | 公開日 | 2009-08-04 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of the lamin A/C R482W mutant responsible for dominant familial partial lipodystrophy (FPLD).
Acta Crystallogr.,Sect.F, 65, 2009
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6QNX
 | | Structure of the SA2/SCC1/CTCF complex | | 分子名称: | Cohesin subunit SA-2, Double-strand-break repair protein rad21 homolog, Transcriptional repressor CTCF | | 著者 | Li, Y, Muir, K.W, Panne, D. | | 登録日 | 2019-02-12 | | 公開日 | 2020-01-22 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The structural basis for cohesin-CTCF-anchored loops.
Nature, 578, 2020
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6R0C
 | | Human-D02 Nucleosome Core Particle with biotin-streptavidin label | | 分子名称: | DNA (142-MER), Histone H2A type 1, Histone H2B type 1-C/E/F/G/I, ... | | 著者 | Pye, V.E, Wilson, M.D, Cherepanov, P, Costa, A. | | 登録日 | 2019-03-12 | | 公開日 | 2019-09-25 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Retroviral integration into nucleosomes through DNA looping and sliding along the histone octamer.
Nat Commun, 10, 2019
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6R94
 | | Cryo-EM structure of NCP_THF2(-3) | | 分子名称: | Histone H2A type 1-B/E, Histone H2B type 1-J, Histone H3.1, ... | | 著者 | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | | 登録日 | 2019-04-02 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | DNA damage detection in nucleosomes involves DNA register shifting.
Nature, 571, 2019
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6R6P
 | | Structure of XBP1u-paused ribosome nascent chain complex (rotated state) | | 分子名称: | 18S rRNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | | 著者 | Shanmuganathan, V, Cheng, J, Berninghausen, O, Beckmann, R. | | 登録日 | 2019-03-27 | | 公開日 | 2019-07-10 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural and mutational analysis of the ribosome-arresting human XBP1u.
Elife, 8, 2019
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3GR4
 | | Activator-Bound Structure of Human Pyruvate Kinase M2 | | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, 1-[(2,6-difluorophenyl)sulfonyl]-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Hong, B, Dimov, S, Tempel, W, Auld, D, Thomas, C, Boxer, M, Jianq, J.-K, Skoumbourdis, A, Min, S, Southall, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Inglese, J, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2009-03-24 | | 公開日 | 2009-04-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Activator-Bound Structures of Human Pyruvate Kinase M2
to be published
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3GQY
 | | Activator-Bound Structure of Human Pyruvate Kinase M2 | | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, 1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[(4-methoxyphenyl)sulfonyl]piperazine, L(+)-TARTARIC ACID, ... | | 著者 | Hong, B, Dimov, S, Tempel, W, Auld, D, Thomas, C, Boxer, M, Jianq, J.-K, Skoumbourdis, A, Min, S, Southall, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Inglese, J, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2009-03-24 | | 公開日 | 2009-04-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Activator-Bound Structures of Human Pyruvate Kinase M2
to be published
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3H6O
 | | Activator-Bound Structure of Human Pyruvate Kinase M2 | | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, 6-(2-fluorobenzyl)-2,4-dimethyl-4,6-dihydro-5H-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one, Pyruvate kinase isozymes M1/M2, ... | | 著者 | Hong, B, Dimov, S, Tempel, W, Auld, D, Thomas, C, Boxer, M, Jianq, J.-K, Skoumbourdis, A, Min, S, Southall, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Inglese, J, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2009-04-23 | | 公開日 | 2009-05-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Activator-Bound Structures of Human Pyruvate Kinase M2
to be published
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4QGC
 | | crystal structure of PKM2-K422R mutant | | 分子名称: | GLYCEROL, POTASSIUM ION, Pyruvate kinase PKM, ... | | 著者 | Wang, P, Sun, C, Zhu, T, Xu, Y. | | 登録日 | 2014-05-22 | | 公開日 | 2015-02-25 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.296 Å) | | 主引用文献 | Structural insight into mechanisms for dynamic regulation of PKM2.
Protein Cell, 6, 2015
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4QG6
 | | crystal structure of PKM2-Y105E mutant | | 分子名称: | PROLINE, Pyruvate kinase PKM | | 著者 | Wang, P, Sun, C, Zhu, T, Xu, Y. | | 登録日 | 2014-05-22 | | 公開日 | 2015-02-25 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (3.207 Å) | | 主引用文献 | Structural insight into mechanisms for dynamic regulation of PKM2.
Protein Cell, 6, 2015
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4QG8
 | | crystal structure of PKM2-K305Q mutant | | 分子名称: | GLYCEROL, MAGNESIUM ION, MALONATE ION, ... | | 著者 | Wang, P, Sun, C, Zhu, T, Xu, Y. | | 登録日 | 2014-05-22 | | 公開日 | 2015-02-25 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural insight into mechanisms for dynamic regulation of PKM2.
Protein Cell, 6, 2015
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4QG9
 | | crystal structure of PKM2-R399E mutant | | 分子名称: | ACETATE ION, MAGNESIUM ION, Pyruvate kinase PKM | | 著者 | Wang, P, Sun, C, Zhu, T, Xu, Y. | | 登録日 | 2014-05-22 | | 公開日 | 2015-02-25 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.381 Å) | | 主引用文献 | Structural insight into mechanisms for dynamic regulation of PKM2.
Protein Cell, 6, 2015
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4RPP
 | | crystal structure of PKM2-K422R mutant bound with FBP | | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, Pyruvate kinase PKM | | 著者 | Wang, P, Sun, C, Zhu, T, Xu, Y. | | 登録日 | 2014-10-31 | | 公開日 | 2015-02-25 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.585 Å) | | 主引用文献 | Structural insight into mechanisms for dynamic regulation of PKM2.
Protein Cell, 6, 2015
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3VHX
 | | The crystal structure of Arf6-MKLP1 (Mitotic kinesin-like protein 1) complex | | 分子名称: | ADP-ribosylation factor 6, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Makyio, H, Takei, T, Ohgi, H, Takahashi, S, Takatsu, H, Ueda, T, Kanaho, Y, Xie, Y, Shin, H.W, Kamikubo, H, Kataoka, M, Kawasaki, M, Kato, R, Wakatsuki, S, Nakayama, K. | | 登録日 | 2011-09-12 | | 公開日 | 2012-05-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Structural basis for Arf6-MKLP1 complex formation on the Flemming body responsible for cytokinesis
Embo J., 31, 2012
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4M38
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3W99
 | | Crystal Structure of Human Nucleosome Core Particle lacking H4 N-terminal region | | 分子名称: | 146-mer DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Iwasaki, W, Miya, Y, Horikoshi, N, Osakabe, A, Tachiwana, H, Shibata, T, Kagawa, W, Kurumizaka, H. | | 登録日 | 2013-04-01 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Contribution of histone N-terminal tails to the structure and stability of nucleosomes
FEBS Open Bio, 3, 2013
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3W98
 | | Crystal Structure of Human Nucleosome Core Particle lacking H3.1 N-terminal region | | 分子名称: | 146-mer DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Iwasaki, W, Miya, Y, Horikoshi, N, Osakabe, A, Tachiwana, H, Shibata, T, Kagawa, W, Kurumizaka, H. | | 登録日 | 2013-04-01 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.42 Å) | | 主引用文献 | Contribution of histone N-terminal tails to the structure and stability of nucleosomes
FEBS Open Bio, 3, 2013
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3W97
 | | Crystal Structure of Human Nucleosome Core Particle lacking H2B N-terminal region | | 分子名称: | 146-mer DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Iwasaki, W, Miya, Y, Horikoshi, N, Osakabe, A, Tachiwana, H, Shibata, T, Kagawa, W, Kurumizaka, H. | | 登録日 | 2013-04-01 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Contribution of histone N-terminal tails to the structure and stability of nucleosomes
FEBS Open Bio, 3, 2013
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