4RPP

crystal structure of PKM2-K422R mutant bound with FBP

Summary for 4RPP

• Entry DOI: 10.2210/pdb4rpp/pdb
• Related: 4QG6 4QG8 4QG9 4QGC
• Descriptor: Pyruvate kinase PKM, 1,6-di-O-phosphono-beta-D-fructofuranose (3 entities in total)
• Functional Keywords: pkm2, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 234957.59

Authors

Wang, P.,Sun, C.,Zhu, T.,Xu, Y. (deposition date: 2014-10-31, release date: 2015-02-25, Last modification date: 2023-04-05)

• Primary citation: Wang, P.,Sun, C.,Zhu, T.,Xu, Y.; Structural insight into mechanisms for dynamic regulation of PKM2.; Protein Cell, 6:275-287, 2015; PubMed: 25645022; DOI: 10.1007/s13238-015-0132-x

Experimental method

X-RAY DIFFRACTION (2.585 Å)