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3UMM
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BU of 3umm by Molmil
Formylglycinamide ribonucleotide amidotransferase from Salmonella typhimurium: Role of the ATP complexation and glutaminase domain in catalytic coupling
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Anand, R, Morar, M, Tanwar, A.S, Panjikar, S.
登録日2011-11-14
公開日2012-06-06
最終更新日2025-03-26
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Formylglycinamide ribonucleotide amidotransferase from Salmonella typhimurium: role of ATP complexation and the glutaminase domain in catalytic coupling
Acta Crystallogr.,Sect.D, 68, 2012
3UGJ
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BU of 3ugj by Molmil
Formyl Glycinamide ribonucletide amidotransferase from Salmonella Typhimurum: Role of the ATP complexation and glutaminase domain in catalytic coupling
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Phosphoribosylformylglycinamidine synthase, ...
著者Morar, M, Tanwar, A.S, Panjikar, S, Anand, R.
登録日2011-11-02
公開日2012-06-06
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Formylglycinamide ribonucleotide amidotransferase from Salmonella typhimurium: role of ATP complexation and the glutaminase domain in catalytic coupling
Acta Crystallogr.,Sect.D, 68, 2012
4AT1
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BU of 4at1 by Molmil
STRUCTURAL CONSEQUENCES OF EFFECTOR BINDING TO THE T STATE OF ASPARTATE CARBAMOYLTRANSFERASE. CRYSTAL STRUCTURES OF THE UNLIGATED AND ATP-, AND CTP-COMPLEXED ENZYMES AT 2.6-ANGSTROMS RESOLUTION
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ASPARTATE CARBAMOYLTRANSFERASE (T STATE), CATALYTIC CHAIN, ...
著者Stevens, R.C, Gouaux, J.E, Lipscomb, W.N.
登録日1990-04-26
公開日1990-10-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural consequences of effector binding to the T state of aspartate carbamoyltransferase: crystal structures of the unligated and ATP- and CTP-complexed enzymes at 2.6-A resolution.
Biochemistry, 29, 1990
2Y5J
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BU of 2y5j by Molmil
Crystal structure of Burkholderia cenocepacia dihydropteroate synthase.
分子名称: 1,2-ETHANEDIOL, DIHYDROPTEROATE SYNTHASE
著者Morgan, R.E, Batot, G.O, Dement, J.M, Rao, V.A, Eadsforth, T.C, Hunter, W.N.
登録日2011-01-13
公開日2011-01-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Crystal Structures of Burkholderia Cenocepacia Dihydropteroate Synthase in the Apo-Form and Complexed with the Product 7,8-Dihydropteroate.
Bmc Struct.Biol., 11, 2011
3NVA
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BU of 3nva by Molmil
Dimeric form of CTP synthase from Sulfolobus solfataricus
分子名称: CTP synthase
著者Harris, P, Willemoes, M, Lauritsen, I, Johansson, E, Jensen, K.F.
登録日2010-07-08
公開日2010-09-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.504 Å)
主引用文献Structure of the dimeric form of CTP synthase from Sulfolobus solfataricus
Acta Crystallogr.,Sect.F, 67, 2011
8U7J
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BU of 8u7j by Molmil
Crystal Structure of Staphylococcus aureus PLP synthase complex
分子名称: GLUTAMINE, PHOSPHATE ION, Pyridoxal 5'-phosphate synthase subunit PdxS, ...
著者Barra, A.L.C, Brognaro, H, Betzel, C, Nascimento, A.S.
登録日2023-09-15
公開日2024-07-24
最終更新日2024-07-31
実験手法X-RAY DIFFRACTION (3.02 Å)
主引用文献Structure and dynamics of the staphylococcal pyridoxal 5-phosphate synthase complex reveal transient interactions at the enzyme interface.
J.Biol.Chem., 300, 2024
2Y5S
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BU of 2y5s by Molmil
Crystal structure of Burkholderia cenocepacia dihydropteroate synthase complexed with 7,8-dihydropteroate.
分子名称: 1,2-ETHANEDIOL, 7,8-DIHYDROPTEROATE, CHLORIDE ION, ...
著者Morgan, R.E, Batot, G.O, Dement, J.M, Rao, V.A, Eadsforth, T.C, Hunter, W.N.
登録日2011-01-17
公開日2011-01-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structures of Burkholderia Cenocepacia Dihydropteroate Synthase in the Apo-Form and Complexed with the Product 7,8-Dihydropteroate.
Bmc Struct.Biol., 11, 2011
5U3C
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BU of 5u3c by Molmil
CryoEM structure of the CTP synthase filament at 4.6 Angstrom resolution
分子名称: ADENOSINE-5'-DIPHOSPHATE, CTP synthase, CYTIDINE-5'-TRIPHOSPHATE
著者Kollman, J.M, Lynch, E.M.
登録日2016-12-01
公開日2017-04-26
最終更新日2024-11-20
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Human CTP synthase filament structure reveals the active enzyme conformation.
Nat. Struct. Mol. Biol., 24, 2017
9DVF
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BU of 9dvf by Molmil
Structure of the native PLP synthase subunit PdxS from Methanosarcina acetivorans
分子名称: Pyridoxal 5'-phosphate synthase subunit PdxS
著者Agnew, A, Humm, E, Zhou, K, Gunsalus, R, Zhou, Z.H.
登録日2024-10-07
公開日2024-10-30
最終更新日2025-01-22
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Structure and identification of the native PLP synthase complex from Methanosarcina acetivorans lysate.
Mbio, 16, 2025
5U6R
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BU of 5u6r by Molmil
E. coli CTP synthase CC mutant filament (product-bound)
分子名称: ADENOSINE-5'-DIPHOSPHATE, CTP synthase, CYTIDINE-5'-TRIPHOSPHATE
著者Kollman, J.M, Lynch, E.M.
登録日2016-12-08
公開日2017-04-26
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (5.7 Å)
主引用文献Human CTP synthase filament structure reveals the active enzyme conformation.
Nat. Struct. Mol. Biol., 24, 2017
5VDR
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BU of 5vdr by Molmil
Human cyclic GMP-AMP synthase (cGAS) in complex with 3',3'-cdIMP
分子名称: 3',3'-cdIMP, Cyclic GMP-AMP synthase, ZINC ION
著者Byrnes, L.J, Hall, J.D.
登録日2017-04-03
公開日2017-09-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.042 Å)
主引用文献The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.
Protein Sci., 26, 2017
5VDP
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BU of 5vdp by Molmil
Human cyclic GMP-AMP synthase (cGAS) in complex with 2',3'-cGAMP
分子名称: Cyclic GMP-AMP synthase, SULFATE ION, ZINC ION, ...
著者Byrnes, L.J, Hall, J.D.
登録日2017-04-03
公開日2017-09-27
最終更新日2024-12-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.
Protein Sci., 26, 2017
5VDO
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BU of 5vdo by Molmil
Human cyclic GMP-AMP synthase (cGAS) in complex with 2',2'-cGAMP
分子名称: 2-amino-9-[(1R,3R,6R,8R,9R,11S,14R,16R,17R,18R)-16-(6-amino-9H-purin-9-yl)-3,11,17,18-tetrahydroxy-3,11-dioxido-2,4,7,10,12,15-hexaoxa-3,11-diphosphatricyclo[12.2.1.1~6,9~]octadec-8-yl]-1,9-dihydro-6H-purin-6-one, Cyclic GMP-AMP synthase, ZINC ION
著者Byrnes, L.J, Hall, J.D.
登録日2017-04-03
公開日2017-09-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.218 Å)
主引用文献The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.
Protein Sci., 26, 2017
5VDQ
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BU of 5vdq by Molmil
Human cyclic GMP-AMP synthase (cGAS) in complex with 2',5'-GpAp
分子名称: 2',5'-GpAp, Cyclic GMP-AMP synthase, ZINC ION
著者Byrnes, L.J, Hall, J.D.
登録日2017-04-03
公開日2017-09-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.246 Å)
主引用文献The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.
Protein Sci., 26, 2017
5VDU
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BU of 5vdu by Molmil
Human cyclic GMP-AMP synthase (cGAS) in complex with Compound F2
分子名称: 2-(pyridin-2-yl)pyrimidine, Cyclic GMP-AMP synthase, ZINC ION
著者Byrnes, L.J, Hall, J.D.
登録日2017-04-03
公開日2017-09-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.729 Å)
主引用文献The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.
Protein Sci., 26, 2017
5VDV
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BU of 5vdv by Molmil
Human cyclic GMP-AMP synthase (cGAS) in complex with Compound F3
分子名称: Cyclic GMP-AMP synthase, SULFATE ION, ZINC ION, ...
著者Byrnes, L.J, Hall, J.D.
登録日2017-04-03
公開日2017-09-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.998 Å)
主引用文献The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.
Protein Sci., 26, 2017
5VDT
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BU of 5vdt by Molmil
Human cyclic GMP-AMP synthase (cGAS) in complex with 3',3'-cGAMP
分子名称: 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, Cyclic GMP-AMP synthase, ZINC ION
著者Byrnes, L.J, Hall, J.D.
登録日2017-04-03
公開日2017-09-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.576 Å)
主引用文献The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.
Protein Sci., 26, 2017
5VDW
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BU of 5vdw by Molmil
Human cyclic GMP-AMP synthase (cGAS) in complex with Compound F1
分子名称: Cyclic GMP-AMP synthase, ZINC ION, [2-(1,3-thiazol-4-yl)-1H-benzimidazol-1-yl]acetic acid
著者Byrnes, L.J, Hall, J.D.
登録日2017-04-03
公開日2017-09-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.711 Å)
主引用文献The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.
Protein Sci., 26, 2017
5VDS
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BU of 5vds by Molmil
Human cyclic GMP-AMP synthase (cGAS) in complex with 3',3'-cdUMP
分子名称: 3',3'-cdUMP, Cyclic GMP-AMP synthase, ZINC ION
著者Byrnes, L.J, Hall, J.D.
登録日2017-04-03
公開日2017-09-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.766 Å)
主引用文献The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.
Protein Sci., 26, 2017
8QOC
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BU of 8qoc by Molmil
Crystal structure of Staphylococcus aureus PLP Synthase (Pdx1)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ...
著者Ullah, N, Wrenger, C, Betzel, C.
登録日2023-09-28
公開日2024-10-02
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献Structure and dynamics of the staphylococcal pyridoxal 5-phosphate synthase complex reveal transient interactions at the enzyme interface.
J.Biol.Chem., 300, 2024
2P4F
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BU of 2p4f by Molmil
Crystal Structure of Atp11 functional domain from Candida Glabrata
分子名称: HEXAETHYLENE GLYCOL, Similar to sp|P32453 Saccharomyces cerevisiae YNL315c ATP11
著者Ludlam, A.V, Brunzelle, J.S, Gatti, D.L, Ackerman, S.H.
登録日2007-03-12
公開日2008-03-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal Structure of Atp11 functional domain from Candida Glabrata
To be Published
7JT6
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BU of 7jt6 by Molmil
Mycobacterium tuberculosis dethiobiotin synthetase in complex with Tetrazole 2
分子名称: ATP-dependent dethiobiotin synthetase BioD, GLYCEROL, SULFATE ION, ...
著者Pederick, J.P, Bean, J.H, Bruning, J.B.
登録日2020-08-17
公開日2021-09-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Inhibition of Mycobacterium tuberculosis Dethiobiotin Synthase ( Mt DTBS): Toward Next-Generation Antituberculosis Agents.
Acs Chem.Biol., 16, 2021
7JT5
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BU of 7jt5 by Molmil
Mycobacterium tuberculosis dethiobiotin synthetase in complex with fragment analogue 9
分子名称: ATP-dependent dethiobiotin synthetase BioD, GLYCEROL, SULFATE ION, ...
著者Pederick, J.P, Bruning, J.B.
登録日2020-08-17
公開日2021-09-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Inhibition of Mycobacterium tuberculosis Dethiobiotin Synthase ( Mt DTBS): Toward Next-Generation Antituberculosis Agents.
Acs Chem.Biol., 16, 2021
7RIG
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BU of 7rig by Molmil
Structure of ACLY-D1026A-substrates
分子名称: (3S)-citryl-Coenzyme A, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ...
著者Wei, X, Marmorstein, R.
登録日2021-07-19
公開日2023-05-10
最終更新日2025-05-28
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Allosteric role of the citrate synthase homology domain of ATP citrate lyase.
Nat Commun, 14, 2023
7RKZ
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BU of 7rkz by Molmil
Structure of ACLY D1026A-substrates-asym-int
分子名称: (3S)-citryl-Coenzyme A, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ...
著者Wei, X, Marmorstein, R.
登録日2021-07-22
公開日2023-05-10
最終更新日2025-05-21
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Allosteric role of the citrate synthase homology domain of ATP citrate lyase.
Nat Commun, 14, 2023

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件を2025-07-09に公開中

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