3KFW
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3KH3
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3KI0
| Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-D | 分子名称: | 3-(morpholin-4-ylmethyl)-1,5-dihydro-6H-[1,2]diazepino[4,5,6-cd]indol-6-one, CHLORIDE ION, Cholix toxin | 著者 | Jorgensen, R, Edwards, P.R, Merrill, A.R. | 登録日 | 2009-10-31 | 公開日 | 2010-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | 主引用文献 | Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae To be Published
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3KG6
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3KH2
| Crystal structure of the P1 bacteriophage Doc toxin (F68S) in complex with the Phd antitoxin (L17M/V39A). Northeast Structural Genomics targets ER385-ER386 | 分子名称: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, Death on curing protein, ... | 著者 | Arbing, M.A, Kuzin, A.P, Su, M, Abashidze, M, Verdon, G, Liu, M, Xiao, R, Acton, T, Inouye, M, Montelione, G.T, Woychik, N.A, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-10-29 | 公開日 | 2010-08-18 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Crystal Structures of Phd-Doc, HigA, and YeeU Establish Multiple Evolutionary Links between Microbial Growth-Regulating Toxin-Antitoxin Systems. Structure, 18, 2010
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3KJ0
| Mcl-1 in complex with Bim BH3 mutant I2dY | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bcl-2-like protein 11, Induced myeloid leukemia cell differentiation protein Mcl-1 | 著者 | Fire, E, Grant, R.A, Keating, A.E. | 登録日 | 2009-11-02 | 公開日 | 2010-02-16 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Mcl-1-Bim complexes accommodate surprising point mutations via minor structural changes. Protein Sci., 19, 2010
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2QME
| Crystal structure of human RAC3 in complex with CRIB domain of human p21-activated kinase 1 (PAK1) | 分子名称: | CRIB domain of the Serine/threonine-protein kinase PAK 1, GLYCEROL, MAGNESIUM ION, ... | 著者 | Ugochukwu, E, Yang, X, Elkins, J.M, Burgess-Brown, N, Bunkoczi, G, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A, von Delft, F, Knapp, S, Doyle, D, Structural Genomics Consortium (SGC) | 登録日 | 2007-07-16 | 公開日 | 2007-08-28 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | The crystal structure of the human RAC3 in complex with the CRIB domain of human p21-activated kinase 1 (PAK1). To be Published
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3KDS
| apo-FtsH crystal structure | 分子名称: | Cell division protein FtsH, N-{(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl}-3-naphthalen-2-yl-L-alanyl-L-alaninamide, ZINC ION | 著者 | Bieniossek, C, Niederhauser, B, Baumann, U. | 登録日 | 2009-10-23 | 公開日 | 2009-12-01 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.601 Å) | 主引用文献 | The crystal structure of apo-FtsH reveals domain movements necessary for substrate unfolding and translocation Proc.Natl.Acad.Sci.USA, 106, 2009
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6UJB
| Integrin alpha-v beta-8 in complex with the Fabs C6D4 and 11D12v2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C6D4 heavy chain Fab, ... | 著者 | Campbell, M.G, Cormier, A, Cheng, Y, Nishimura, S.L. | 登録日 | 2019-10-02 | 公開日 | 2020-02-05 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.51 Å) | 主引用文献 | Cryo-EM Reveals Integrin-Mediated TGF-beta Activation without Release from Latent TGF-beta. Cell, 180, 2020
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6UJS
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3KJP
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2QBW
| The crystal structure of PDZ-Fibronectin fusion protein | 分子名称: | PDZ-Fibronectin fusion protein, Polypeptide | 著者 | Huang, J, Makabe, K, Koide, A, Koide, S. | 登録日 | 2007-06-18 | 公開日 | 2008-04-22 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Design of protein function leaps by directed domain interface evolution. Proc.Natl.Acad.Sci.Usa, 105, 2008
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6UJN
| P-glycoprotein mutant-C952A-with BDE100 | 分子名称: | 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1 | 著者 | Aller, S.G, Le, C.A. | 登録日 | 2019-10-03 | 公開日 | 2020-05-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.98 Å) | 主引用文献 | Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein. Iucrj, 7, 2020
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3KEV
| X-ray crystal structure of a DCUN1 domain-containing protein from Galdieria sulfuraria | 分子名称: | ACETATE ION, Galieria sulfuraria DCUN1 domain-containing protein, SULFATE ION | 著者 | Burgie, E.S, Bingman, C.A, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | 登録日 | 2009-10-26 | 公開日 | 2009-12-01 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Structural architecture of Galdieria sulphuraria DCN1L. Proteins, 79, 2011
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3KFG
| Major mouse urinary protein IV complexed with 2-heptanone | 分子名称: | (2S)-2-ethylhexan-1-ol, CHLORIDE ION, Major urinary protein 4, ... | 著者 | Perez-Miller, S, Zou, Q, Hurley, T.D. | 登録日 | 2009-10-27 | 公開日 | 2010-06-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | High resolution X-ray structures of mouse major urinary protein nasal isoform in complex with pheromones. Protein Sci., 19, 2010
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3KFL
| Leishmania major methionyl-tRNA synthetase in complex with methionyladenylate and pyrophosphate | 分子名称: | 1,2-ETHANEDIOL, FORMIC ACID, MAGNESIUM ION, ... | 著者 | Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP) | 登録日 | 2009-10-27 | 公開日 | 2010-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of Leishmania major methionyl-tRNA synthetase in complex with intermediate products methionyladenylate and pyrophosphate. Biochimie, 93, 2011
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3KG8
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3KAY
| Crystal structure of abscisic acid receptor PYL1 | 分子名称: | Putative uncharacterized protein At5g46790 | 著者 | Zhou, X.E, Melcher, K, Ng, L.-M, Soon, F.-F, Xu, Y, Suino-Powell, K.M, Kovach, A, Li, J, Xu, H.E. | 登録日 | 2009-10-19 | 公開日 | 2009-12-08 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Agate-latch-lock mechanism for hormone signalling by abscisic acid receptors Nature, 462, 2009
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3KGX
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3KHI
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6ESQ
| Structure of the acetoacetyl-CoA thiolase/HMG-CoA synthase complex from Methanothermococcus thermolithotrophicus soaked with acetyl-CoA | 分子名称: | CHLORIDE ION, COENZYME A, HydroxyMethylGlutaryl-CoA synthase, ... | 著者 | Voegeli, B, Engilberge, S, Girard, E, Riobe, F, Maury, O, Erb, J.T, Shima, S, Wagner, T. | 登録日 | 2017-10-24 | 公開日 | 2018-03-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Archaeal acetoacetyl-CoA thiolase/HMG-CoA synthase complex channels the intermediate via a fused CoA-binding site. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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2QS1
| Crystal structure of the GluR5 ligand binding core dimer in complex with UBP315 at 1.80 Angstroms resolution | 分子名称: | 3-({3-[(2S)-2-amino-2-carboxyethyl]-5-methyl-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl}methyl)-4,5-dibromothiophene-2-carboxylic acid, CHLORIDE ION, Glutamate receptor, ... | 著者 | Alushin, G.M, Jane, D.E, Mayer, M.L. | 登録日 | 2007-07-30 | 公開日 | 2008-08-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Binding site and ligand flexibility revealed by high resolution crystal structures of GluK1 competitive antagonists. Neuropharmacology, 60, 2011
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3KI2
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3KCK
| A Novel Chemotype of Kinase Inhibitors | 分子名称: | 3-chloro-4-(4H-3,4,7-triazadibenzo[cd,f]azulen-6-yl)phenol, Tyrosine-protein kinase JAK2 | 著者 | Zuccola, H.J, Wang, T, Ledeboer, M.W. | 登録日 | 2009-10-21 | 公開日 | 2009-11-24 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A novel chemotype of kinase inhibitors: Discovery of 3,4-ring fused 7-azaindoles and deazapurines as potent JAK2 inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
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3KB0
| Crystal structure of abscisic acid-bound PYL2 | 分子名称: | (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, Putative uncharacterized protein At2g26040 | 著者 | Zhou, X.E, Melcher, K, Ng, L.-M, Soon, F.-F, Xu, Y, Suino-Powell, K.M, Kovach, A, Li, J, Xu, H.E. | 登録日 | 2009-10-19 | 公開日 | 2009-12-08 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Agate-latch-lock mechanism for hormone signalling by abscisic acid receptors Nature, 462, 2009
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