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3KFW
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Uncharacterized protein Rv0674 from Mycobacterium tuberculosis
分子名称: Uncharacterized protein
著者Ramagopal, U.A, Toro, R, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2009-10-28
公開日2009-12-01
最終更新日2021-02-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Uncharacterized protein Rv0674 from Mycobacterium tuberculosis
To be Published
3KH3
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BU of 3kh3 by Molmil
Crystal structure of human Cu/Zn superoxide dismutase recombinantly produced in Leishmania tarantolae; P212121 crystal form containing 12 chains in the asymmetric unit
分子名称: COPPER (II) ION, SULFATE ION, Superoxide dismutase [Cu-Zn], ...
著者Gazdag, E.M, Blankenfeldt, W.
登録日2009-10-30
公開日2010-08-11
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Purification and crystallization of human Cu/Zn superoxide dismutase recombinantly produced in the protozoan Leishmania tarentolae.
Acta Crystallogr.,Sect.F, 66, 2010
3KI0
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BU of 3ki0 by Molmil
Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-D
分子名称: 3-(morpholin-4-ylmethyl)-1,5-dihydro-6H-[1,2]diazepino[4,5,6-cd]indol-6-one, CHLORIDE ION, Cholix toxin
著者Jorgensen, R, Edwards, P.R, Merrill, A.R.
登録日2009-10-31
公開日2010-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae
To be Published
3KG6
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BU of 3kg6 by Molmil
Dehydratase domain from CurF module of Curacin polyketide synthase
分子名称: CALCIUM ION, CurF
著者Akey, D.L, Smith, J.L.
登録日2009-10-28
公開日2010-01-19
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structures of Dehydratase Domains from the Curacin Polyketide Biosynthetic Pathway.
Structure, 18, 2010
3KH2
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BU of 3kh2 by Molmil
Crystal structure of the P1 bacteriophage Doc toxin (F68S) in complex with the Phd antitoxin (L17M/V39A). Northeast Structural Genomics targets ER385-ER386
分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, Death on curing protein, ...
著者Arbing, M.A, Kuzin, A.P, Su, M, Abashidze, M, Verdon, G, Liu, M, Xiao, R, Acton, T, Inouye, M, Montelione, G.T, Woychik, N.A, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2009-10-29
公開日2010-08-18
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Crystal Structures of Phd-Doc, HigA, and YeeU Establish Multiple Evolutionary Links between Microbial Growth-Regulating Toxin-Antitoxin Systems.
Structure, 18, 2010
3KJ0
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BU of 3kj0 by Molmil
Mcl-1 in complex with Bim BH3 mutant I2dY
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bcl-2-like protein 11, Induced myeloid leukemia cell differentiation protein Mcl-1
著者Fire, E, Grant, R.A, Keating, A.E.
登録日2009-11-02
公開日2010-02-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mcl-1-Bim complexes accommodate surprising point mutations via minor structural changes.
Protein Sci., 19, 2010
2QME
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BU of 2qme by Molmil
Crystal structure of human RAC3 in complex with CRIB domain of human p21-activated kinase 1 (PAK1)
分子名称: CRIB domain of the Serine/threonine-protein kinase PAK 1, GLYCEROL, MAGNESIUM ION, ...
著者Ugochukwu, E, Yang, X, Elkins, J.M, Burgess-Brown, N, Bunkoczi, G, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A, von Delft, F, Knapp, S, Doyle, D, Structural Genomics Consortium (SGC)
登録日2007-07-16
公開日2007-08-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The crystal structure of the human RAC3 in complex with the CRIB domain of human p21-activated kinase 1 (PAK1).
To be Published
3KDS
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BU of 3kds by Molmil
apo-FtsH crystal structure
分子名称: Cell division protein FtsH, N-{(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl}-3-naphthalen-2-yl-L-alanyl-L-alaninamide, ZINC ION
著者Bieniossek, C, Niederhauser, B, Baumann, U.
登録日2009-10-23
公開日2009-12-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献The crystal structure of apo-FtsH reveals domain movements necessary for substrate unfolding and translocation
Proc.Natl.Acad.Sci.USA, 106, 2009
6UJB
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BU of 6ujb by Molmil
Integrin alpha-v beta-8 in complex with the Fabs C6D4 and 11D12v2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C6D4 heavy chain Fab, ...
著者Campbell, M.G, Cormier, A, Cheng, Y, Nishimura, S.L.
登録日2019-10-02
公開日2020-02-05
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.51 Å)
主引用文献Cryo-EM Reveals Integrin-Mediated TGF-beta Activation without Release from Latent TGF-beta.
Cell, 180, 2020
6UJS
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BU of 6ujs by Molmil
P-glycoprotein mutant-F728A and C952A-with BDE100
分子名称: 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1
著者Aller, S.G, Le, C.A.
登録日2019-10-03
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.17 Å)
主引用文献Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein.
Iucrj, 7, 2020
3KJP
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Crystal Structure of hPOT1V2-GGTTAGGGTTAG
分子名称: 5'-D(*G*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3', Protection of telomeres protein 1
著者Nandakumar, J, Cech, T.R, Podell, E.R.
登録日2009-11-03
公開日2010-01-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA.
Proc.Natl.Acad.Sci.USA, 107, 2010
2QBW
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BU of 2qbw by Molmil
The crystal structure of PDZ-Fibronectin fusion protein
分子名称: PDZ-Fibronectin fusion protein, Polypeptide
著者Huang, J, Makabe, K, Koide, A, Koide, S.
登録日2007-06-18
公開日2008-04-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Design of protein function leaps by directed domain interface evolution.
Proc.Natl.Acad.Sci.Usa, 105, 2008
6UJN
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BU of 6ujn by Molmil
P-glycoprotein mutant-C952A-with BDE100
分子名称: 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1
著者Aller, S.G, Le, C.A.
登録日2019-10-03
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.98 Å)
主引用文献Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein.
Iucrj, 7, 2020
3KEV
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BU of 3kev by Molmil
X-ray crystal structure of a DCUN1 domain-containing protein from Galdieria sulfuraria
分子名称: ACETATE ION, Galieria sulfuraria DCUN1 domain-containing protein, SULFATE ION
著者Burgie, E.S, Bingman, C.A, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG)
登録日2009-10-26
公開日2009-12-01
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structural architecture of Galdieria sulphuraria DCN1L.
Proteins, 79, 2011
3KFG
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BU of 3kfg by Molmil
Major mouse urinary protein IV complexed with 2-heptanone
分子名称: (2S)-2-ethylhexan-1-ol, CHLORIDE ION, Major urinary protein 4, ...
著者Perez-Miller, S, Zou, Q, Hurley, T.D.
登録日2009-10-27
公開日2010-06-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献High resolution X-ray structures of mouse major urinary protein nasal isoform in complex with pheromones.
Protein Sci., 19, 2010
3KFL
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BU of 3kfl by Molmil
Leishmania major methionyl-tRNA synthetase in complex with methionyladenylate and pyrophosphate
分子名称: 1,2-ETHANEDIOL, FORMIC ACID, MAGNESIUM ION, ...
著者Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日2009-10-27
公開日2010-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of Leishmania major methionyl-tRNA synthetase in complex with intermediate products methionyladenylate and pyrophosphate.
Biochimie, 93, 2011
3KG8
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BU of 3kg8 by Molmil
Dehydratase domain from CurJ module of Curacin polyketide synthase
分子名称: CurJ
著者Akey, D.L, Smith, J.L.
登録日2009-10-28
公開日2010-01-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal Structures of Dehydratase Domains from the Curacin Polyketide Biosynthetic Pathway.
Structure, 18, 2010
3KAY
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Crystal structure of abscisic acid receptor PYL1
分子名称: Putative uncharacterized protein At5g46790
著者Zhou, X.E, Melcher, K, Ng, L.-M, Soon, F.-F, Xu, Y, Suino-Powell, K.M, Kovach, A, Li, J, Xu, H.E.
登録日2009-10-19
公開日2009-12-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Agate-latch-lock mechanism for hormone signalling by abscisic acid receptors
Nature, 462, 2009
3KGX
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BU of 3kgx by Molmil
Crystal structure of Putative aminotransferase (AAH25799.1) from MUS MUSCULUS at 1.80 A resolution
分子名称: 1,2-ETHANEDIOL, Alanine-glyoxylate aminotransferase, CHLORIDE ION, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2009-10-29
公開日2009-11-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of Putative aminotransferase (AAH25799.1) from MUS MUSCULUS at 1.80 A resolution
To be published
3KHI
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Crystal structure of a Putative Metal-dependent Hydrolase (YP_001336084.1) from Klebsiella pneumoniae subsp. pneumoniae MGH 78578 at 1.95 A resolution
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Putative Metal-dependent Hydrolase, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2009-10-30
公開日2009-11-10
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The Structure of Mlc Titration Factor A (MtfA/YeeI) Reveals a Prototypical Zinc Metallopeptidase Related to Anthrax Lethal Factor.
J.Bacteriol., 194, 2012
6ESQ
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BU of 6esq by Molmil
Structure of the acetoacetyl-CoA thiolase/HMG-CoA synthase complex from Methanothermococcus thermolithotrophicus soaked with acetyl-CoA
分子名称: CHLORIDE ION, COENZYME A, HydroxyMethylGlutaryl-CoA synthase, ...
著者Voegeli, B, Engilberge, S, Girard, E, Riobe, F, Maury, O, Erb, J.T, Shima, S, Wagner, T.
登録日2017-10-24
公開日2018-03-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Archaeal acetoacetyl-CoA thiolase/HMG-CoA synthase complex channels the intermediate via a fused CoA-binding site.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
2QS1
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BU of 2qs1 by Molmil
Crystal structure of the GluR5 ligand binding core dimer in complex with UBP315 at 1.80 Angstroms resolution
分子名称: 3-({3-[(2S)-2-amino-2-carboxyethyl]-5-methyl-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl}methyl)-4,5-dibromothiophene-2-carboxylic acid, CHLORIDE ION, Glutamate receptor, ...
著者Alushin, G.M, Jane, D.E, Mayer, M.L.
登録日2007-07-30
公開日2008-08-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Binding site and ligand flexibility revealed by high resolution crystal structures of GluK1 competitive antagonists.
Neuropharmacology, 60, 2011
3KI2
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Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-G
分子名称: 2-(4-methylpiperazin-1-yl)benzo[c][1,5]naphthyridin-6(5H)-one, Cholix toxin
著者Jorgensen, R, Edwards, P.R, Merrill, A.R.
登録日2009-10-31
公開日2010-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae
To be Published
3KCK
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A Novel Chemotype of Kinase Inhibitors
分子名称: 3-chloro-4-(4H-3,4,7-triazadibenzo[cd,f]azulen-6-yl)phenol, Tyrosine-protein kinase JAK2
著者Zuccola, H.J, Wang, T, Ledeboer, M.W.
登録日2009-10-21
公開日2009-11-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A novel chemotype of kinase inhibitors: Discovery of 3,4-ring fused 7-azaindoles and deazapurines as potent JAK2 inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
3KB0
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Crystal structure of abscisic acid-bound PYL2
分子名称: (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, Putative uncharacterized protein At2g26040
著者Zhou, X.E, Melcher, K, Ng, L.-M, Soon, F.-F, Xu, Y, Suino-Powell, K.M, Kovach, A, Li, J, Xu, H.E.
登録日2009-10-19
公開日2009-12-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Agate-latch-lock mechanism for hormone signalling by abscisic acid receptors
Nature, 462, 2009

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