2QS1

Crystal structure of the GluR5 ligand binding core dimer in complex with UBP315 at 1.80 Angstroms resolution

Summary for 2QS1

Entry DOI	10.2210/pdb2qs1/pdb
Related	1TXF 2F34 2F35 2F36 2QS2 2QS3 2QS4
Descriptor	Glutamate receptor, ionotropic kainate 1, CHLORIDE ION, PENTAETHYLENE GLYCOL, ... (5 entities in total)
Functional Keywords	membrane protein, cell junction, glycoprotein, ion transport, ionic channel, phosphorylation, postsynaptic cell membrane, receptor, rna editing, synapse, transmembrane, transport
Biological source	Rattus norvegicus (rat) More
Cellular location	Cell membrane; Multi-pass membrane protein: P22756
Total number of polymer chains	2
Total formula weight	59992.81
Authors	Alushin, G.M.,Jane, D.E.,Mayer, M.L. (deposition date: 2007-07-30, release date: 2008-08-05, Last modification date: 2023-08-30)
Primary citation	Alushin, G.M.,Jane, D.,Mayer, M.L. Binding site and ligand flexibility revealed by high resolution crystal structures of GluK1 competitive antagonists. Neuropharmacology, 60:126-134, 2011 Cited by PubMed: 20558186 DOI: 10.1016/j.neuropharm.2010.06.002 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation