PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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8RFF	Crystal structure of N-terminal SARS-CoV-2 nsp1 in complex with fragment hit 6A6 refined against the anomalous diffraction data 分子名称: 1,3-benzothiazol-2-amine, Host translation inhibitor nsp1 著者 Ma, S, Damfo, S, Mykhaylyk, V, Kozielski, F. 登録日 2023-12-12 公開日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.31 Å) 主引用文献 High-confidence placement of low-occupancy fragments into electron density using the anomalous signal of sulfur and halogen atoms. Acta Crystallogr D Struct Biol, 80, 2024
2YAC	Crystal structure of Polo-like kinase 1 in complex with NMS-P937 分子名称: 1-(2-HYDROXYETHYL)-8-[[5-(4-METHYLPIPERAZIN-1-YL)-2-(TRIFLUOROMETHOXY)PHENYL]AMINO]-4,5-DIHYDROPYRIMIDO[5,4-G]INDAZOLE-3-CARBOXAMIDE, L(+)-TARTARIC ACID, SERINE/THREONINE-PROTEIN KINASE PLK1, ... 著者 Bertrand, J.A, Bossi, R.T. 登録日 2011-02-18 公開日 2011-04-06 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Nms-P937, a 4,5-Dihydro-1H-Pyrazolo[4,3-H]Quinazoline Derivative as Potent and Selective Polo-Like Kinase 1 Inhibitor. Bioorg.Med.Chem.Lett., 21, 2011
5DHR	Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with a novel inhibitor 分子名称: 5'-azido-8-[(2-{[2-(1H-benzimidazol-2-yl)ethyl]amino}-2-oxoethyl)sulfanyl]-5'-deoxyadenosine, CITRIC ACID, GLYCEROL, ... 著者 Gelin, M, Paoletti, J, Assairi, L, Huteau, V, Pochet, S, Labesse, G. 登録日 2015-08-31 公開日 2016-09-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 8-Thioalkyl-adenosine derivatives inhibit Listeria monocytogenes NAD kinase through a novel binding mode. Eur.J.Med.Chem., 124, 2016
8RF4	Crystal structure of N-terminal SARS-CoV-2 nsp1 in complex with fragment hit 9D4 refined against the anomalous diffraction data 分子名称: 4-chloranyl-1~{H}-indazol-3-amine, Host translation inhibitor nsp1 著者 Ma, S, Damfo, S, Mykhaylyk, V, Kozielski, F. 登録日 2023-12-12 公開日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.11 Å) 主引用文献 High-confidence placement of low-occupancy fragments into electron density using the anomalous signal of sulfur and halogen atoms. Acta Crystallogr D Struct Biol, 80, 2024
5DI3	Crystal structure of Arl13B in complex with Arl3 of Chlamydomonas reinhardtii 分子名称: ADP-ribosylation factor-like protein 13B, ADP-ribosylation factor-like protein 3, MAGNESIUM ION, ... 著者 Gotthardt, K, Lokaj, M, Falk, N, Koerner, C, Giessl, A, Wittinghofer, A. 登録日 2015-08-31 公開日 2015-11-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A G-protein activation cascade from Arl13B to Arl3 and implications for ciliary targeting of lipidated proteins. Elife, 4, 2015
8RF8	Crystal structure of N-terminal SARS-CoV-2 nsp1 in complex with fragment hit 11A7_AL6 refined against the anomalous diffraction data 分子名称: 6-bromanyl-1,3-benzothiazol-2-amine, Host translation inhibitor nsp1 著者 Ma, S, Damfo, S, Mykhaylyk, V, Kozielski, F. 登録日 2023-12-12 公開日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 High-confidence placement of low-occupancy fragments into electron density using the anomalous signal of sulfur and halogen atoms. Acta Crystallogr D Struct Biol, 80, 2024
8RPL	AMP-forming acetyl-CoA synthetase from Chloroflexota bacterium with bound acetyl AMP 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Acetate--CoA ligase, MAGNESIUM ION, ... 著者 Striska, K, Palm, G.J, Lammers, M. 登録日 2024-01-16 公開日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 The AMP-forming acetyl-CoA-synthetase is regulated by lysine acetylation and has an intrinsic phosphotransacetylase activity to adjust its activity to the cellular acetyl-phosphate level Nature Comm, 2024
8RT9	Stalk complex full-length structure (TrwJ/VirB5-TrwI/VirB6) from the fully-assembled R388 type IV secretion system determined by cryo-EM. 分子名称: TrwI protein, TrwJ protein 著者 Mace, K, Waksman, G. 登録日 2024-01-25 公開日 2024-06-19 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (2.97 Å) 主引用文献 Cryo-EM structure of a conjugative type IV secretion system suggests a molecular switch regulating pilus biogenesis. Embo J., 2024
8RNU	CryoEM structure of recombinant human Bri2 BRICHOS oligomers 分子名称: Integral membrane protein 2B 著者 Chen, G, Johansson, J, Hebert, H. 登録日 2024-01-11 公開日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Molecular basis for different substrate-binding sites and chaperone functions of the BRICHOS domain. Protein Sci., 33, 2024
2G04	Crystal structure of fatty acid-CoA racemase from Mycobacterium tuberculosis H37Rv 分子名称: PROBABLE FATTY-ACID-CoA RACEMASE FAR 著者 Lee, K.S, Park, S.M, Rhee, K.H, Bang, W.G, Hwang, K.Y, Chi, Y.M. 登録日 2006-02-11 公開日 2007-01-02 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of fatty acid-CoA racemase from Mycobacterium tuberculosis H37Rv Proteins, 64, 2006
8RYT	Structural characterization of Thogoto Virus nucleoprotein provides insights into RNA encapsidation and assembly 分子名称: Nucleoprotein 著者 Roske, Y, Mikirtumov, V, Daumke, O, Kudryashev, M, Dick, A. 登録日 2024-02-09 公開日 2024-06-19 実験手法 ELECTRON MICROSCOPY (18 Å) 主引用文献 Structural characterization of Thogoto Virus nucleoprotein provides insights into viral RNA encapsidation and RNP assembly. Structure, 2024
2G47	Crystal structure of human insulin-degrading enzyme in complex with amyloid-beta (1-40) 分子名称: 1,4-DIETHYLENE DIOXIDE, Insulin-degrading enzyme, amyloid protein beta A4 著者 Shen, Y, Tang, W.-J. 登録日 2006-02-21 公開日 2006-10-24 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism. Nature, 443, 2006
8RT8	Conformation-C of the full-length outer membrane core complex (TrwH/VirB7, TrwF/VirB9, TrwE/VirB10CTD) from the fully-assembled R388 type IV secretion system determined by cryo-EM. 分子名称: TrwE protein, TrwF protein, TrwH protein 著者 Mace, K, Waksman, G. 登録日 2024-01-25 公開日 2024-06-19 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.05 Å) 主引用文献 Cryo-EM structure of a conjugative type IV secretion system suggests a molecular switch regulating pilus biogenesis. Embo J., 2024
2G1G	Solution structure of the anticodon loop of S. Pombe tRNAi including the naturally occurring N6-threonyl adenine 分子名称: 5'-R(*AP*CP*GP*GP*GP*CP*UP*CP*AP*UP*(T6A)P*AP*CP*CP*CP*GP*U)-3' 著者 Lescrinier, E. 登録日 2006-02-14 公開日 2006-06-20 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 The naturally occurring N6-threonyl adenine in anticodon loop of Schizosaccharomyces pombe tRNAi causes formation of a unique U-turn motif Nucleic Acids Res., 34, 2006
2G1W	NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1 分子名称: 5'-R(*GP*GP*GP*GP*UP*GP*GP*CP*UP*CP*CP*CP*CP*UP*AP*AP*CP*AP*GP*CP*CP*G)-3' 著者 Nonin-Lecomte, S, Dardel, F. 登録日 2006-02-15 公開日 2006-04-11 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1: new insights into the recoding event of the ribosomal trans-translation. Nucleic Acids Res., 34, 2006
8RT7	Conformation-B of the full-length outer membrane core complex (TrwH/VirB7, TrwF/VirB9, TrwE/VirB10CTD) from the fully-assembled R388 type IV secretion system determined by cryo-EM. 分子名称: TrwE protein, TrwF protein, TrwH 著者 Mace, K, Waksman, G. 登録日 2024-01-25 公開日 2024-06-19 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (2.93 Å) 主引用文献 Cryo-EM structure of a conjugative type IV secretion system suggests a molecular switch regulating pilus biogenesis. Embo J., 2024
5KJF	V222I horse liver alcohol dehydrogenase complexed with NAD+ and trifluoroethanol 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, Alcohol dehydrogenase E chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ... 著者 Plapp, B.V. 登録日 2016-06-18 公開日 2016-07-27 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Contribution of buried distal amino acid residues in horse liver alcohol dehydrogenase to structure and catalysis. Protein Sci., 27, 2018
2G66	Crystal structure of a collagen-like peptide with 3(S)Hyp in the Xaa position 分子名称: collagen 著者 Schumacher, M.A, Mizuno, K, Bachinger, H.P. 登録日 2006-02-24 公開日 2006-08-08 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The Crystal Structure of a Collagen-like Polypeptide with 3(S)-Hydroxyproline Residues in the Xaa Position Forms a Standard 7/2 Collagen Triple Helix J.Biol.Chem., 281, 2006
2G29	crystal structure of the periplasmic nitrate-binding protein NrtA from Synechocystis PCC 6803 分子名称: NITRATE ION, Nitrate transport protein nrtA 著者 Koropatkin, N.M, Pakrasi, H.B, Smith, T.J. 登録日 2006-02-15 公開日 2006-07-11 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Atomic structure of a nitrate-binding protein crucial for photosynthetic productivity Proc.Natl.Acad.Sci.Usa, 103, 2006
5DIU	The Fk1 domain of FKBP51 in complex with the new synthetic ligand 2-(3-((R)-1-((S)-1-((S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl)piperidine-2-carboxamido)-3-(3,4-dimethoxyphenyl)propyl)phenoxy)acetic acid 分子名称: Peptidyl-prolyl cis-trans isomerase FKBP5, {3-[(1R)-1-[({(2S)-1-[(2S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl]piperidin-2-yl}carbonyl)amino]-3-(3,4-dimethoxyphenyl)propyl]phenoxy}acetic acid 著者 Gaali, S, Feng, X, Sippel, C, Bracher, A, Hausch, F. 登録日 2015-09-01 公開日 2016-03-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Rapid, Structure-Based Exploration of Pipecolic Acid Amides as Novel Selective Antagonists of the FK506-Binding Protein 51. J.Med.Chem., 59, 2016
5DHP	Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with a novel inhibitor 分子名称: 8-({2-oxo-2-[(2-phenylethyl)amino]ethyl}sulfanyl)adenosine, CITRIC ACID, GLYCEROL, ... 著者 Gelin, M, Paoletti, J, Assairi, L, Huteau, V, Pochet, S, Labesse, G. 登録日 2015-08-31 公開日 2016-09-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 8-Thioalkyl-adenosine derivatives inhibit Listeria monocytogenes NAD kinase through a novel binding mode. Eur.J.Med.Chem., 124, 2016
8RT4	O-layer structure (TrwH/VirB7, TrwF/VirB9CTD, TrwE/VirB10CTD) of the outer membrane core complex from the fully-assembled R388 type IV secretion system determined by cryo-EM. 分子名称: TrwE protein, TrwF protein, TrwH protein 著者 Mace, K, Waksman, G. 登録日 2024-01-25 公開日 2024-06-19 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (2.46 Å) 主引用文献 Cryo-EM structure of a conjugative type IV secretion system suggests a molecular switch regulating pilus biogenesis. Embo J., 2024
2YRN	Solution structure of the CH domain from Human Neuron navigator 2 分子名称: Neuron navigator 2 isoform 4 著者 Tomizawa, T, Tochio, N, Koshiba, S, Inoue, M, Nakamura, Y, Furukawa, Y, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-04-02 公開日 2008-02-12 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the CH domain from Human Neuron navigator 2 To be Published
2G6U	Solution structures of MP-2: a high affinity miniprotein ligand to Streptavidin 分子名称: Miniprotein MP2 著者 Fox, R.O, Mukherjee, M. 登録日 2006-02-25 公開日 2007-04-10 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Structural studies of high affinity miniprotein ligands to Streptavidin To be Published
2YSA	Solution structure of the zinc finger CCHC domain from the human retinoblastoma-binding protein 6 (Retinoblastoma-binding Q protein 1, RBQ-1) 分子名称: Retinoblastoma-binding protein 6, ZINC ION 著者 Ohnishi, S, Sato, M, Tochio, N, Koshiba, S, Harada, T, Watanabe, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-04-03 公開日 2007-10-09 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the zinc finger CCHC domain from the human retinoblastoma-binding protein 6 (Retinoblastoma-binding Q protein 1, RBQ-1) To be Published

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