8RNU

CryoEM structure of recombinant human Bri2 BRICHOS oligomers

Summary for 8RNU

• Entry DOI: 10.2210/pdb8rnu/pdb
• EMDB information: 19395
• Descriptor: Integral membrane protein 2B (1 entity in total)
• Functional Keywords: chaperone, anti-amyloid, dementia, bri2
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 12
• Total formula weight: 167399.82

Authors

Chen, G.,Johansson, J.,Hebert, H. (deposition date: 2024-01-11, release date: 2024-06-19)

• Primary citation: Chen, G.,Wang, Y.,Zheng, Z.,Jiang, W.,Leppert, A.,Zhong, X.,Belorusova, A.,Siegal, G.,Jegerschold, C.,Koeck, P.J.B.,Abelein, A.,Hebert, H.,Knight, S.D.,Johansson, J.; Molecular basis for different substrate-binding sites and chaperone functions of the BRICHOS domain.; Protein Sci., 33:e5063-e5063, 2024; PubMed: 38864729; DOI: 10.1002/pro.5063

Experimental method

ELECTRON MICROSCOPY (3.4 Å)