PDB: 2596 件ウェブページステータス検索Chemie searchBIRD

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4U4U	Crystal structure of Lycorine bound to the yeast 80S ribosome 分子名称: (1S,2S,12bS,12cS)-2,4,5,7,12b,12c-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol, 18S ribosomal RNA, 25S ribosomal RNA, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-24 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
6CF1	Proteus vulgaris HigA antitoxin structure 分子名称: Antitoxin HigA, POTASSIUM ION 著者 Schureck, M.A, Hoffer, E.D, Ei Cho, S, Dunham, C.M. 登録日 2018-02-13 公開日 2019-02-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis of transcriptional regulation by the HigA antitoxin. Mol.Microbiol., 111, 2019
9BUL	The structure of NiaR from Thermotoga maritima bound to nicotinic acid 分子名称: FE (II) ION, NICOTINIC ACID, PROLINE, ... 著者 Glasfeld, A, Cheng, D.W.C, Li, Y. 登録日 2024-05-17 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The structure of NiaR from Thermotoga maritima bound to nicotinic acid To Be Published
2IF5	Structure of the POZ domain of human LRF, a master regulator of oncogenesis 分子名称: PRASEODYMIUM ION, Zinc finger and BTB domain-containing protein 7A 著者 Schubot, F.D, Waugh, D.S, Tropea, J. 登録日 2006-09-20 公開日 2006-11-21 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of the POZ domain of human LRF, a master regulator of oncogenesis. Biochem.Biophys.Res.Commun., 351, 2006
2IWD	Oxacilloyl-acylated MecR1 extracellular antibiotic-sensor domain. 分子名称: (2R,4S)-5,5-dimethyl-2-[(1R)-1-{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}-2-oxoethyl]-1,3-thiazolidine-4-carb oxylic acid, Methicillin resistance mecR1 protein 著者 Marrero, A, Mallorqui-Fernandez, G, Guevara, T, Garcia-Castellanos, R, Gomis-Ruth, F.X. 登録日 2006-06-27 公開日 2006-07-03 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Unbound and Acylated Structures of the Mecr1 Extracellular Antibiotic-Sensor Domain Provide Insights Into the Signal-Transduction System that Triggers Methicillin Resistance. J.Mol.Biol., 361, 2006
2IWB	MecR1 unbound extracellular antibiotic-sensor domain. 分子名称: GLYCEROL, METHICILLIN RESISTANCE MECR1 PROTEIN, NICKEL (II) ION, ... 著者 Marrero, A, Mallorqui-Fernandez, G, Guevara, T, Garcia-Castellanos, R, Gomis-Ruth, F.X. 登録日 2006-06-27 公開日 2006-07-04 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Unbound and Acylated Structures of the Mecr1 Extracellular Antibiotic-Sensor Domain Provide Insights Into the Signal-Transduction System that Triggers Methicillin Resistance. J.Mol.Biol., 361, 2006
8SLN	Crystal structure of Deinococcus geothermalis PprI complexed with ssDNA 分子名称: DNA (29-MER), MANGANESE (II) ION, Zn dependent hydrolase fused to HTH domain, ... 著者 Zhao, Y, Lu, H. 登録日 2023-04-23 公開日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The Deinococcus protease PprI senses DNA damage by directly interacting with single-stranded DNA. Nat Commun, 15, 2024
8SLM	Crystal structure of Deinococcus geothermalis PprI 分子名称: MANGANESE (II) ION, SULFATE ION, Zn dependent hydrolase fused to HTH domain, ... 著者 Zhao, Y, Lu, H. 登録日 2023-04-23 公開日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 The Deinococcus protease PprI senses DNA damage by directly interacting with single-stranded DNA. Nat Commun, 15, 2024
1SV4	Crystal Structure of Yan-SAM 分子名称: Ets DNA-binding protein pokkuri 著者 Qiao, F, Song, H, Kim, C.A, Sawaya, M.R, Hunter, J.B, Gingery, M, Rebay, I, Courey, A.J, Bowie, J.U. 登録日 2004-03-27 公開日 2004-07-27 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Derepression by depolymerization; structural insights into the regulation of yan by mae. Cell(Cambridge,Mass.), 118, 2004
7X7H	Crystal structure of Fructose regulator/Histidine phosphocarrier protein complex from Vibrio cholerae 分子名称: CALCIUM ION, Catabolite repressor/activator, HPr family phosphocarrier protein 著者 Kim, M.-K, Zhang, J, Yoon, C.-K, Seok, Y.-J. 登録日 2022-03-09 公開日 2023-03-15 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 HPr prevents FruR-mediated facilitation of RNA polymerase binding to the fru promoter in Vibrio cholerae. Nucleic Acids Res., 51, 2023
5K5J	Homo sapiens CCCTC-binding factor (CTCF) ZnF5-8 and DNA complex structure in space group P41212 分子名称: ACETATE ION, DNA (5'-D(*CP*CP*CP*TP*GP*CP*TP*GP*GP*CP*AP*AP*C)-3'), DNA (5'-D(*TP*TP*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*G)-3'), ... 著者 Hashimoto, H, Cheng, X. 登録日 2016-05-23 公開日 2017-05-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.287 Å) 主引用文献 Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA. Mol. Cell, 66, 2017
4RTS	Complex of Escherichia coli DNA Adenine Methyltransferase (DAM) with AdoMet and a 5-bp non-canonical site (GTCTA) 分子名称: DNA (5'-D(*AP*CP*TP*TP*AP*GP*AP*CP*TP*TP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*GP*TP*CP*TP*AP*AP*G)-3'), DNA adenine methylase, ... 著者 Horton, J.R, Cheng, X. 登録日 2014-11-15 公開日 2015-04-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression. Nucleic Acids Res., 43, 2015
7ZVI	Non-canonical Staphylococcus aureus pathogenicity island repression 分子名称: Orf22, Sri 著者 Miguel-Romero, L, Alqasmi, M, Bacarizo, J, Marina, A, Penades, J.R. 登録日 2022-05-16 公開日 2022-09-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.973 Å) 主引用文献 Non-canonical Staphylococcus aureus pathogenicity island repression. Nucleic Acids Res., 50, 2022
6PF6	Crystal structure of TS-DHFR from Cryptosporidium hominis in complex with NADPH, FdUMP and 2-(4-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl)benzamido)terephthalic acid 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2-({4-[(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]benzene-1-carbonyl}amino)benzene-1,4-dicarboxylic acid, Thymidylate synthase,Thymidylate synthase 著者 Czyzyk, D.L, Valhondo, M, Jorgensen, W.L, Anderson, K.S. 登録日 2019-06-21 公開日 2019-10-16 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.502 Å) 主引用文献 Structure activity relationship towards design of cryptosporidium specific thymidylate synthase inhibitors. Eur.J.Med.Chem., 183, 2019
6PF5	Crystal structure of human thymidylate synthase Delta (7-29) in complex with dUMP and 2-(2-(4-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl)benzamido)-4-methoxyphenyl)acetic acid 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Thymidylate synthase, [2-({4-[(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]benzene-1-carbonyl}amino)-4-methoxyphenyl]acetic acid 著者 Czyzyk, D.J, Valhondo, M, Jorgensen, W.L, Anderson, K.S. 登録日 2019-06-21 公開日 2019-10-02 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Structure activity relationship towards design of cryptosporidium specific thymidylate synthase inhibitors. Eur.J.Med.Chem., 183, 2019
2ISY	Crystal structure of the nickel-activated two-domain iron-dependent regulator (IdeR) 分子名称: Iron-dependent repressor ideR, NICKEL (II) ION, PHOSPHATE ION 著者 Wisedchaisri, G, Chou, C.J, Wu, M, Roach, C, Rice, A.E, Holmes, R.K, Beeson, C, Hol, W.G. 登録日 2006-10-18 公開日 2007-02-13 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.955 Å) 主引用文献 Crystal structures, metal activation, and DNA-binding properties of two-domain IdeR from Mycobacterium tuberculosis Biochemistry, 46, 2007
2ISZ	Crystal structure of a two-domain IdeR-DNA complex crystal form I 分子名称: Iron-dependent repressor ideR, NICKEL (II) ION, SODIUM ION, ... 著者 Wisedchaisri, G, Chou, C.J, Wu, M, Roach, C, Rice, A.E, Holmes, R.K, Beeson, C, Hol, W.G. 登録日 2006-10-18 公開日 2007-02-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.403 Å) 主引用文献 Crystal structures, metal activation, and DNA-binding properties of two-domain IdeR from Mycobacterium tuberculosis Biochemistry, 46, 2007
3E4U	Crystal Structure of the Wild-Type Human BCL6 BTB/POZ Domain 分子名称: B-cell lymphoma 6 protein 著者 Stead, M.A, Rosbrook, G.O, Hadden, J.M, Trinh, C.H, Carr, S.B, Wright, S.C. 登録日 2008-08-12 公開日 2008-12-09 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of the wild-type human BCL6 POZ domain. Acta Crystallogr.,Sect.F, 64, 2008
6WPA	Structure of AvaR1 bound to DNA half-site 分子名称: AvaR1, PAL2-1-5'-GC 著者 Kapoor, I, Olivares, P.J, Nair, S.K. 登録日 2020-04-26 公開日 2020-07-22 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.09 Å) 主引用文献 Biochemical basis for the regulation of biosynthesis of antiparasitics by bacterial hormones. Elife, 9, 2020
7B0C	[4Fe-4S]-NsrR complexed to 23-bp HmpA1 operator fragment 分子名称: DNA (5'-D(P*AP*AP*CP*AP*CP*GP*AP*AP*TP*AP*TP*CP*AP*TP*CP*TP*AP*CP*CP*AP*AP*TP*T)-3'), DNA (5'-D(P*AP*AP*TP*TP*GP*GP*TP*AP*GP*AP*TP*GP*AP*TP*AP*TP*TP*CP*GP*TP*GP*TP*T)-3'), HTH-type transcriptional repressor NsrR, ... 著者 Rohac, R, Fontecilla-Camps, J.C, Volbeda, A. 登録日 2020-11-19 公開日 2022-06-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural determinants of DNA recognition by the NO sensor NsrR and related Rrf2-type [FeS]-transcription factors. Commun Biol, 5, 2022
6WP9	AvaR1 bound to Avenolide 分子名称: (5S)-5-[(6R)-6-hydroxy-6-methyl-5-oxooctyl]furan-2(5H)-one, AvaR1 著者 Kapoor, I, Olivares, P.J, Nair, S.K. 登録日 2020-04-26 公開日 2020-07-22 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Biochemical basis for the regulation of biosynthesis of antiparasitics by bacterial hormones. Elife, 9, 2020
7UJL	Bacteriophage Lambda Red-Beta N-terminal domain helical assembly in complex with dsDNA 分子名称: Complementary DNA, Recombination protein bet, Template DNA 著者 Newing, T.P, Tolun, G. 登録日 2022-03-31 公開日 2022-10-05 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Red beta 177 annealase structure reveals details of oligomerization and lambda Red-mediated homologous DNA recombination Nat Commun, 13, 2022
7NSQ	Structure of ErmDL-Telithromycin-stalled 70S E. coli ribosomal complex with A and P-tRNA 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Beckert, B, Wilson, D.N. 登録日 2021-03-08 公開日 2021-07-14 最終更新日 2021-08-11 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics. Nat Commun, 12, 2021
7NSO	Structure of ErmDL-Erythromycin-stalled 70S E. coli ribosomal complex with P-tRNA 分子名称: 16S rRNA (1540-MER), 23S rRNA (2903-MER), 30S ribosomal protein S10, ... 著者 Beckert, B, Wilson, D.N. 登録日 2021-03-08 公開日 2021-07-14 最終更新日 2021-08-11 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics. Nat Commun, 12, 2021
7NSP	Structure of ErmDL-Erythromycin-stalled 70S E. coli ribosomal complex with A and P-tRNA 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Beckert, B, Wilson, D.N. 登録日 2021-03-08 公開日 2021-08-11 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics. Nat Commun, 12, 2021

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