8SLN

Crystal structure of Deinococcus geothermalis PprI complexed with ssDNA

Summary for 8SLN

• Entry DOI: 10.2210/pdb8sln/pdb
• Descriptor: Zn dependent hydrolase fused to HTH domain, IrrE ortholog, DNA (29-MER), MANGANESE (II) ION (3 entities in total)
• Functional Keywords: dna damage response, single-stranded dna, dimer, protease, hydrolase, hydrolase-dna complex, hydrolase/dna
• Biological source: Deinococcus geothermalis DSM 11300; More
• Total number of polymer chains: 2
• Total formula weight: 40460.35

Authors

Zhao, Y.,Lu, H. (deposition date: 2023-04-23, release date: 2024-03-13)

• Primary citation: Lu, H.,Chen, Z.,Xie, T.,Zhong, S.,Suo, S.,Song, S.,Wang, L.,Xu, H.,Tian, B.,Zhao, Y.,Zhou, R.,Hua, Y.; The Deinococcus protease PprI senses DNA damage by directly interacting with single-stranded DNA.; Nat Commun, 15:1892-1892, 2024; PubMed: 38424107; DOI: 10.1038/s41467-024-46208-9

Experimental method

X-RAY DIFFRACTION (2.2 Å)