PDB: 1848 件ウェブページステータス検索Chemie searchBIRD

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8SCM	Bst DNA polymerase I Large Fragment mutant F710Y/D598A with 3'-amino primer, dGTP, and calcium time-resolved 8h 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... 著者 Fang, Z, Lelyveld, V.S, Szostak, J.W. 登録日 2023-04-05 公開日 2023-10-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity. Science, 382, 2023
8SCN	Bst DNA polymerase I Large Fragment mutant F710Y/D598A with 3'-amino primer, dGTP, and calcium time-resolved 24h (Product State) 分子名称: CALCIUM ION, DIPHOSPHATE, DNA polymerase I, ... 著者 Fang, Z, Lelyveld, V.S, Szostak, J.W. 登録日 2023-04-05 公開日 2023-10-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity. Science, 382, 2023
8SCO	Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 0h (Ground State) 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 3'-Amino DNA primer, CALCIUM ION, ... 著者 Fang, Z, Lelyveld, V.S, Szostak, J.W. 登録日 2023-04-05 公開日 2023-10-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity. Science, 382, 2023
8SCP	Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 1h 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... 著者 Fang, Z, Lelyveld, V.S, Szostak, J.W. 登録日 2023-04-05 公開日 2023-10-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity. Science, 382, 2023
8SCQ	Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 2h 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... 著者 Fang, Z, Lelyveld, V.S, Szostak, J.W. 登録日 2023-04-05 公開日 2023-10-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity. Science, 382, 2023
8SCR	Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 4h 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... 著者 Fang, Z, Lelyveld, V.S, Szostak, J.W. 登録日 2023-04-05 公開日 2023-10-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity. Science, 382, 2023
8SCS	Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 8h 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... 著者 Fang, Z, Lelyveld, V.S, Szostak, J.W. 登録日 2023-04-05 公開日 2023-10-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity. Science, 382, 2023
8SCT	Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 24h 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... 著者 Fang, Z, Lelyveld, V.S, Szostak, J.W. 登録日 2023-04-05 公開日 2023-10-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity. Science, 382, 2023
8SCU	Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 48h (Product State) 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... 著者 Fang, Z, Lelyveld, V.S, Szostak, J.W. 登録日 2023-04-05 公開日 2023-10-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity. Science, 382, 2023
6S2E	Cryo-EM structure of Ctf18-1-8 in complex with the catalytic domain of DNA polymerase epsilon 分子名称: Chromosome transmission fidelity protein 18, Chromosome transmission fidelity protein 8, DNA polymerase epsilon catalytic subunit A, ... 著者 Grabarczyk, D.B, Song, B. 登録日 2019-06-20 公開日 2020-07-08 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Ctf18-RFC and DNA Pol ε form a stable leading strand polymerase/clamp loader complex required for normal and perturbed DNA replication. Nucleic Acids Res., 48, 2020
6S2F	Cryo-EM structure of Ctf18-1-8 in complex with the catalytic domain of DNA polymerase epsilon (Class 2) 分子名称: Chromosome transmission fidelity protein 18, Chromosome transmission fidelity protein 8, DNA polymerase epsilon catalytic subunit A, ... 著者 Grabarczyk, D.B, Song, B. 登録日 2019-06-20 公開日 2020-07-08 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (5.8 Å) 主引用文献 Ctf18-RFC and DNA Pol ε form a stable leading strand polymerase/clamp loader complex required for normal and perturbed DNA replication. Nucleic Acids Res., 48, 2020
2L23	NMR structure of the ACID (ACtivator Interacting Domain) of the human mediator Med25 protein 分子名称: Mediator of RNA polymerase II transcription subunit 25 著者 Bontems, F, Monte, D, Dewitte, F, Villeret, V. 登録日 2010-08-10 公開日 2010-11-24 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 NMR structure of the human Mediator MED25 ACID domain. J.Struct.Biol., 174, 2011
1S29	La autoantigen N-terminal domain 分子名称: La protein 著者 Dong, G, Chakshusmathi, G, Wolin, S.L, Reinisch, K.M. 登録日 2004-01-08 公開日 2004-03-23 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of the La motif: a winged helix domain mediates RNA binding via a conserved aromatic patch. Embo J., 23, 2004
2V6Z	Solution Structure of Amino-Terminal Domain of Human DNA Polymerase Epsilon Subunit B 分子名称: DNA POLYMERASE EPSILON SUBUNIT 2 著者 Nuutinen, T, Fredriksson, K, Tossavainen, H, Pospiech, H, Pirila, P, Permi, P, Annila, A, Syvaoja, J.E. 登録日 2007-07-24 公開日 2008-08-05 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 The Solution Structure of the Amino-Terminal Domain of Human DNA Polymerase Epsilon Subunit B is Homologous to C-Domains of Aaa+ Proteins. Nucleic Acids Res., 36, 2008
1S7A	NMR structure of the La motif of human La protein 分子名称: Lupus La protein 著者 Alfano, C, Sanfelice, D, Babon, J, Kelly, G, Jacks, A, Curry, S, Conte, M.R. 登録日 2004-01-29 公開日 2004-04-06 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structural analysis of cooperative RNA binding by the La motif and central RRM domain of human La protein. Nat.Struct.Mol.Biol., 11, 2004
1S79	Solution structure of the central RRM of human La protein 分子名称: Lupus La protein 著者 Alfano, C, Sanfelice, D, Babon, J, Kelly, G, Jacks, A, Curry, S, Conte, M.R. 登録日 2004-01-29 公開日 2004-04-06 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structural analysis of cooperative RNA binding by the La motif and central RRM domain of human La protein. Nat.Struct.Mol.Biol., 11, 2004
2RUH	Chemical Shift Assignments for MIP and MDM2 in bound state 分子名称: E3 ubiquitin-protein ligase Mdm2 著者 Nagata, T, Shirakawa, K, Kobayashi, N, Shiheido, H, Horisawa, K, Katahira, M, Doi, N, Yanagawa, H. 登録日 2014-06-03 公開日 2014-10-15 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural Basis for Inhibition of the MDM2:p53 Interaction by an Optimized MDM2-Binding Peptide Selected with mRNA Display Plos One, 9, 2014
2MAP	Solution structure of the complex formed by the region 2 of E. coli sigmaE and its cognate -10 promoter element non template strand TGTCAAA. 分子名称: DNA, RNA polymerase sigma factor 著者 Campagne, S, Vorholt, J.A, Allain, F.H.-T. 登録日 2013-07-16 公開日 2014-02-19 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural basis for -10 promoter element melting by environmentally induced sigma factors. Nat.Struct.Mol.Biol., 21, 2014
7QTT	Structural organization of a late activated human spliceosome (Baqr, core region) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... 著者 Cretu, C, Pena, V. 登録日 2022-01-15 公開日 2023-05-10 最終更新日 2023-06-14 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of catalytic activation in human splicing. Nature, 617, 2023
4UCJ	X-ray structure and activities of an essential Mononegavirales L- protein domain 分子名称: RNA-DIRECTED RNA POLYMERASE L, SULFATE ION, ZINC ION 著者 Paesen, G.C, Collet, A, Sallamand, C, Debart, F, Vasseur, J.J, Canard, B, Decroly, E, Grimes, J.M. 登録日 2014-12-03 公開日 2015-11-18 最終更新日 2019-04-24 実験手法 X-RAY DIFFRACTION (3.26 Å) 主引用文献 X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain. Nat.Commun., 6, 2015
8CH6	Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex). 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... 著者 Cretu, C, Schmitzova, J, Pena, V. 登録日 2023-02-07 公開日 2023-05-10 最終更新日 2023-06-14 実験手法 ELECTRON MICROSCOPY (5.9 Å) 主引用文献 Structural basis of catalytic activation in human splicing. Nature, 617, 2023
4UCK	X-ray structure and activities of an essential Mononegavirales L- protein domain 分子名称: RNA-DIRECTED RNA POLYMERASE L, S-ADENOSYLMETHIONINE, ZINC ION 著者 Paesen, G.C, Collet, A, Sallamand, C, Debart, F, Vasseur, J.J, Canard, B, Decroly, E, Grimes, J.M. 登録日 2014-12-03 公開日 2015-11-18 最終更新日 2019-04-24 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain. Nat.Commun., 6, 2015
4UD0	X-ray structure and activities of an essential Mononegavirales L- protein domain 分子名称: RNA-DIRECTED RNA POLYMERASE L, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... 著者 Paesen, G.C, Collet, A, Sallamand, C, Debart, F, Vasseur, J.J, Canard, B, Decroly, E, Grimes, J.M. 登録日 2014-12-05 公開日 2015-11-18 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain. Nat.Commun., 6, 2015
4UCL	X-ray structure and activities of an essential Mononegavirales L- protein domain 分子名称: RNA-DIRECTED RNA POLYMERASE L, SULFATE ION, ZINC ION 著者 Paesen, G.C, Collet, A, Sallamand, C, Debart, F, Vasseur, J.J, Canard, B, Decroly, E, Grimes, J.M. 登録日 2014-12-03 公開日 2015-11-18 最終更新日 2019-04-24 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain. Nat.Commun., 6, 2015
4UCY	X-ray structure and activities of an essential Mononegavirales L- protein domain 分子名称: RNA-DIRECTED RNA POLYMERASE L, SULFATE ION, ZINC ION 著者 Paesen, G.C, Collet, A, Sallamand, C, Debart, F, Vasseur, J.J, Canard, B, Decroly, E, Grimes, J.M. 登録日 2014-12-05 公開日 2015-11-18 最終更新日 2019-04-24 実験手法 X-RAY DIFFRACTION (2.83 Å) 主引用文献 X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain. Nat.Commun., 6, 2015

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