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1H10
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HIGH RESOLUTION STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN OF PROTEIN KINASE B/AKT BOUND TO INS(1,3,4,5)-TETRAKISPHOPHATE
分子名称: INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, RAC-ALPHA SERINE/THREONINE KINASE
著者Thomas, C.C, Deak, M, Alessi, D.R, Van Aalten, D.M.F.
登録日2002-07-01
公開日2003-06-27
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献High Resolution Structure of the Pleckstrin Homology Domain of Protein Kinase B/Akt Bound to Phosphatidylinositol (3,4,5)-Trisphosphate
Curr.Biol., 12, 2002
1H11
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2-DEOXY-2-FLURO-B-D-CELLOTRIOSYL/ENZYME INTERMEDIATE COMPLEX OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHEARANS AT 1.08 ANGSTROM RESOLUTION
分子名称: ENDOGLUCANASE 5A, GLYCEROL, SULFATE ION, ...
著者Varrot, A, Davies, G.J.
登録日2002-07-01
公開日2002-08-08
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献Direct Experimental Observation of the Hydrogen-Bonding Network of a Glycosidase Along its Reaction Coordinate Revealed by Atomic Resolution Analyses of Endoglucanase Cel5A
Acta Crystallogr.,Sect.D, 59, 2003
1H12
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Structure of a cold-adapted family 8 xylanase
分子名称: ENDO-1,4-BETA-XYLANASE, alpha-D-xylopyranose, beta-D-xylopyranose
著者Van Petegem, F, Collins, T, Meuwis, M.A, Feller, G, Gerday, C, Van Beeumen, J.
登録日2002-07-02
公開日2003-03-13
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献The Structure of a Cold-Adapted Family 8 Xylanase at 1.3 A Resolution: Structural Adaptations to Cold and Investigation of the Active Site
J.Biol.Chem., 278, 2003
1H13
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Structure of a cold-adapted family 8 xylanase
分子名称: ENDO-1,4-BETA-XYLANASE
著者Van Petegem, F, Collins, T, Meuwis, M.A, Feller, G, Gerday, C, Van Beeumen, J.
登録日2002-07-02
公開日2003-03-13
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献The Structure of a Cold-Adapted Family 8 Xylanase at 1.3 A Resolution: Structural Adaptations to Cold and Investigation of the Active Site
J.Biol.Chem., 278, 2003
1H14
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Structure of a cold-adapted family 8 xylanase
分子名称: ENDO-1,4-BETA-XYLANASE
著者Van Petegem, F, Collins, T, Meuwis, M.A, Feller, G, Gerday, C, Van Beeumen, J.
登録日2002-07-02
公開日2003-03-13
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The Structure of a Cold-Adapted Family 8 Xylanase at 1.3 A Resolution: Structural Adaptations to Cold and Investigation of the Active Site
J.Biol.Chem., 278, 2003
1H15
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X-ray crystal structure of HLA-DRA1*0101/DRB5*0101 complexed with a peptide from Epstein Barr Virus DNA polymerase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DNA POLYMERASE, ...
著者Lang, H, Jacobsen, H, Ikemizu, S, Andersson, C, Harlos, K, Madsen, L, Hjorth, P, Sondergaard, L, Svejgaard, A, Wucherpfennig, K, Stuart, D.I, Bell, J.I, Jones, E.Y, Fugger, L.
登録日2002-07-02
公開日2002-10-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A Functional and Structural Basis for Tcr Cross-Reactivity in Multiple Sclerosis
Nat.Immunol., 3, 2002
1H16
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Pyruvate Formate-Lyase (E.coli) in complex with Pyruvate and CoA
分子名称: COENZYME A, FORMATE ACETYLTRANSFERASE 1, L-TREITOL, ...
著者Becker, A, Kabsch, W.
登録日2002-07-03
公開日2002-11-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献X-Ray Structure of Pyruvate Formate-Lyase in Complex with Pyruvate and Coa.How the Enzyme Uses the Cys-418 Thiyl Radical for Pyruvate Cleavage
J.Biol.Chem., 277, 2002
1H17
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Pyruvate Formate-Lyase (E.coli) in complex with CoA and the substrate analog oxamate
分子名称: COENZYME A, FORMATE ACETYLTRANSFERASE 1, L-TREITOL, ...
著者Becker, A, Kabsch, W.
登録日2002-07-03
公開日2002-11-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献X-Ray Structure of Pyruvate Formate-Lyase in Complex with Pyruvate and Coa.How the Enzyme Uses the Cys-418 Thiyl Radical for Pyruvate Cleavage
J.Biol.Chem., 277, 2002
1H18
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Pyruvate Formate-Lyase (E.coli) in complex with Pyruvate
分子名称: FORMATE ACETYLTRANSFERASE 1, L-TREITOL, PYRUVIC ACID, ...
著者Becker, A, Kabsch, W.
登録日2002-07-04
公開日2002-11-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献X-Ray Structure of Pyruvate Formate-Lyase in Complex with Pyruvate and Coa.How the Enzyme Uses the Cys-418 Thiyl Radical for Pyruvate Cleavage
J.Biol.Chem., 277, 2002
1H19
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STRUCTURE OF [E271Q]LEUKOTRIENE A4 HYDROLASE
分子名称: ACETIC ACID, IMIDAZOLE, LEUKOTRIENE A-4 HYDROLASE, ...
著者Rudberg, P.C, Tholander, F, Thunnissen, M.M.G.M, Haeggstrom, J.Z.
登録日2002-07-04
公開日2002-08-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Leukotriene A4 Hydrolase/Aminopeptidase, Glutamate 271 is a Catalyticresidue with Specific Roles in Two Distinct Enzyme Mechanisms
J.Biol.Chem., 277, 2002
1H1A
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Thermophilic beta-1,4-xylanase from Chaetomium thermophilum
分子名称: CALCIUM ION, Endo-1,4-beta-xylanase, GLYCEROL, ...
著者Hakulinen, N, Rouvinen, J.
登録日2002-07-05
公開日2003-07-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Three-Dimensional Structures of Thermophilic Beta-1,4-Xylanases from Chaetomium Thermophilum and Nonomuraea Flexuosa. Comparison of Twelve Xylanases in Relation to Their Thermal Stability.
Eur.J.Biochem., 270, 2003
1H1B
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Crystal structure of human neutrophil elastase complexed with an inhibitor (GW475151)
分子名称: (2S)-3-METHYL-2-((2R,3S)-3-[(METHYLSULFONYL)AMINO]-1-{[2-(PYRROLIDIN-1-YLMETHYL)-1,3-OXAZOL-4-YL]CARBONYL}PYRROLIDIN-2-YL)BUTANOIC ACID, LEUKOCYTE ELASTASE, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Macdonald, S.J.F, Dowle, M.D, Harrison, L.A, Clarke, G.D.E, Inglis, G.G.A, Johnson, M.R, Smith, R.A, Amour, A, Fleetwood, G, Humphreys, D.C, Molloy, C.R, Dixon, M, Godward, R.E, Wonacott, A.J, Singh, O.M.P, Hodgson, S.T, Hardy, G.W.
登録日2002-07-05
公開日2002-08-29
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of Further Pyrrolidine Trans-Lactams as Inhibitors of Human Neutrophil Elastase (Hne) with Potential as Development Candidates and the Crystal Structure of Hne Complexed with an Inhibitor (Gw475151)
J.Med.Chem., 45, 2002
1H1C
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Histidinol-phosphate aminotransferase (HisC) from Thermotoga maritima
分子名称: HISTIDINOL-PHOSPHATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE
著者Vega, M.C, Fernandez, F.J, Wilmanns, M.
登録日2002-07-08
公開日2004-03-19
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural Studies of the Catalytic Reaction Pathway of a Hyperthermophilic Histidinol-Phosphate Aminotransferase
J.Biol.Chem., 279, 2004
1H1D
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Catechol O-Methyltransferase
分子名称: 1-(3,4,DIHYDROXY-5-NITROPHENYL)-3-{4-[3-(TRIFLUOROMETHYL) PHENYL] PIPERAZIN-1-YL}PROPAN-1-ONE, CATECHOL-O-METHYLTRANSFERASE, MAGNESIUM ION, ...
著者Archer, M, Rodrigues, M.L, Matias, P.M, Bonifacio, M.J, Learmonth, D.A, Soares-da-Silva, P, Carrondo, M.A.
登録日2002-07-12
公開日2003-07-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Kinetics and Crystal Structure of Catechol-O-Methyltransferase Complex with Co-Substrate and a Novel Inhibitor with Potential Therapeutic Application
Mol.Pharmacol., 62, 2002
1H1H
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Crystal Structure of Eosinophil Cationic Protein in Complex with 2',5'-ADP at 2.0 A resolution Reveals the Details of the Ribonucleolytic Active site
分子名称: ADENOSINE-2'-5'-DIPHOSPHATE, EOSINOPHIL CATIONIC PROTEIN
著者Mohan, C.G, Boix, E, Evans, H.R, Nikolovski, Z, Nogues, M.V, Cuchillo, C.M, Acharya, K.R.
登録日2002-07-15
公開日2002-10-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Crystal Structure of Eosinophil Cationic Protein in Complex with 2'5'-Adp at 2.0 A Resolution Reveals the Details of the Ribonucleolytic Active Site
Biochemistry, 41, 2002
1H1I
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CRYSTAL STRUCTURE OF QUERCETIN 2,3-DIOXYGENASE ANAEROBICALLY COMPLEXED WITH THE SUBSTRATE QUERCETN
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Steiner, R.A, Dijkstra, B.W.
登録日2002-07-15
公開日2002-11-28
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Anaerobic Enzyme.Substrate Structures Provide Insight Into the Reaction Mechanism of the Copper- Dependent Quercetin 2,3-Dioxygenase.
Proc.Natl.Acad.Sci.USA, 99, 2002
1H1J
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The SAP domain is a DNA-Binding Domain Capable of Binding S/MAR DNA
分子名称: THO1 PROTEIN
著者Jacobsen, J.O.B, Freund, S.M.V, Bycroft, M.
登録日2002-07-16
公開日2002-08-08
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The Sap Domain is a DNA-Binding Domain Capable of Binding S/Mar DNA
To be Published
1H1K
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THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA
分子名称: RNA
著者Diprose, J.M, Grimes, J.M, Sutton, G.C, Burroughs, J.N, Meyer, A, Maan, S, Mertens, P.P.C, Stuart, D.I.
登録日2002-07-17
公開日2002-09-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (10 Å)
主引用文献The Core of Bluetongue Virus Binds Double-Stranded RNA
J.Virol., 76, 2002
1H1L
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NITROGENASE MO-FE PROTEIN FROM KLEBSIELLA PNEUMONIAE, NIFV MUTANT
分子名称: CHLORIDE ION, CITRIC ACID, FE(8)-S(7) CLUSTER, ...
著者Mayer, S.M, Gormal, C.A, Smith, B.E, Lawson, D.M.
登録日2002-07-18
公開日2002-07-29
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystallographic Analysis of the Mofe Protein of Nitrogenase from a Nifv Mutant of Klebsiella Pneumoniae Identifies Citrate as a Ligand to the Molybdenum of Iron Molybdenum Cofactor (Femoco).
J.Biol.Chem., 277, 2002
1H1M
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CRYSTAL STRUCTURE OF QUERCETIN 2,3-DIOXYGENASE ANAEROBICALLY COMPLEXED WITH THE SUBSTRATE KAEMPFEROL
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Steiner, R.A, Dijkstra, B.W.
登録日2002-07-19
公開日2002-11-28
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Anaerobic Enzyme.Substrate Structures Provide Insight Into the Reaction Mechanism of the Copper- Dependent Quercetin 2,3-Dioxygenase.
Proc.Natl.Acad.Sci.USA, 99, 2002
1H1N
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Atomic resolution structure of the major endoglucanase from Thermoascus aurantiacus
分子名称: ENDO TYPE CELLULASE ENGI
著者Van Petegem, F, Vandenberghe, I, Bhat, M.K, Van Beeumen, J.
登録日2002-07-19
公開日2002-08-12
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Atomic Resolution Structure of the Major Endoglucanase from Thermoascus Aurantiacus
Biochem.Biophys.Res.Commun., 296, 2002
1H1O
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Acidithiobacillus ferrooxidans cytochrome c4 structure supports a complex-induced tuning of electron transfer
分子名称: CYTOCHROME C-552, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Abergel, C, Nitschke, W, Malarte, G, Bruschi, M, Claverie, J.-M, Guidici-Orticoni, M.-T.
登録日2002-07-19
公開日2003-07-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献The Structure of Acidithiobacillus Ferrooxidans C(4)-Cytochrome. A Model for Complex-Induced Electron Transfer Tuning
Structure, 11, 2003
1H1P
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Structure of human Thr160-phospho CDK2/cyclin A complexed with the inhibitor NU2058
分子名称: 6-O-CYCLOHEXYLMETHYL GUANINE, CELL DIVISION PROTEIN KINASE 2, CYCLIN A2
著者Davies, T.G, Noble, M.E.M, Endicott, J.A, Johnson, L.N.
登録日2002-07-21
公開日2002-09-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure-Based Design of a Potent Purine-Based Cyclin-Dependent Kinase Inhibitor
Nat.Struct.Biol., 9, 2002
1H1Q
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Structure of human Thr160-phospho CDK2/cyclin A complexed with the inhibitor NU6094
分子名称: 2-ANILINO-6-CYCLOHEXYLMETHOXYPURINE, CELL DIVISION PROTEIN KINASE 2, CYCLIN A2
著者Davies, T.G, Noble, M.E.M, Endicott, J.A, Johnson, L.N.
登録日2002-07-21
公開日2002-09-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure-Based Design of a Potent Purine-Based Cyclin-Dependent Kinase Inhibitor
Nat.Struct.Biol., 9, 2002
1H1R
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Structure of human Thr160-phospho CDK2/cyclin A complexed with the inhibitor NU6086
分子名称: 6-CYCLOHEXYLMETHOXY-2-(3'-CHLOROANILINO) PURINE, CELL DIVISION PROTEIN KINASE 2, CYCLIN A2
著者Davies, T.G, Noble, M.E.M, Endicott, J.A, Johnson, L.N.
登録日2002-07-21
公開日2002-09-19
最終更新日2019-10-02
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor.
Nat. Struct. Biol., 9, 2002

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