Pyruvate Formate-Lyase (E.coli) in complex with Pyruvate and CoA

Summary for 1H16

Related1CM5 1H17 1H18 1QHM 2PFL 3PFL
DescriptorFORMATE ACETYLTRANSFERASE 1, COENZYME A, PYRUVIC ACID, ... (8 entities in total)
Functional Keywordslyase, glycyl radical enzyme, transferase, acyltransferase
Biological sourceESCHERICHIA COLI
Total number of polymer chains1
Total molecular weight87195.65
Becker, A.,Kabsch, W. (deposition date: 2002-07-03, release date: 2002-11-01, Last modification date: 2019-07-24)
Primary citation
Becker, A.,Kabsch, W.
X-Ray Structure of Pyruvate Formate-Lyase in Complex with Pyruvate and Coa.How the Enzyme Uses the Cys-418 Thiyl Radical for Pyruvate Cleavage
J.Biol.Chem., 277:40036-, 2002
PubMed: 12163496 (PDB entries with the same primary citation)
DOI: 10.1074/JBC.M205821200
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.17611 0.4% 1.6% 1.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report