1H18

Pyruvate Formate-Lyase (E.coli) in complex with Pyruvate

Summary for 1H18

Entry DOI	10.2210/pdb1h18/pdb
Related	1CM5 1H16 1H17 1QHM 2PFL 3PFL
Descriptor	FORMATE ACETYLTRANSFERASE 1, PYRUVIC ACID, SODIUM ION, ... (6 entities in total)
Functional Keywords	lyase, glycyl radical enzyme, transferase, acyltransferase, acetylation
Biological source	ESCHERICHIA COLI
Cellular location	Cytoplasm: P09373
Total number of polymer chains	2
Total formula weight	172452.46
Authors	Becker, A.,Kabsch, W. (deposition date: 2002-07-04, release date: 2002-11-01, Last modification date: 2023-12-13)
Primary citation	Becker, A.,Kabsch, W. X-Ray Structure of Pyruvate Formate-Lyase in Complex with Pyruvate and Coa.How the Enzyme Uses the Cys-418 Thiyl Radical for Pyruvate Cleavage J.Biol.Chem., 277:40036-, 2002 Cited by PubMed: 12163496 DOI: 10.1074/JBC.M205821200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation