1H1D

Catechol O-Methyltransferase

Summary for 1H1D

Entry DOI	10.2210/pdb1h1d/pdb
Related	1VID
Descriptor	CATECHOL-O-METHYLTRANSFERASE, MAGNESIUM ION, S-ADENOSYLMETHIONINE, ... (5 entities in total)
Functional Keywords	transferase, methyltransferase, neurotransmitter degradation
Biological source	RATTUS NORVEGICUS (NORWAY RAT)
Cellular location	Isoform 2: Cytoplasm. Isoform 1: Cell membrane; Single-pass type II membrane protein; Extracellular side: P22734
Total number of polymer chains	1
Total formula weight	25634.53
Authors	Archer, M.,Rodrigues, M.L.,Matias, P.M.,Bonifacio, M.J.,Learmonth, D.A.,Soares-da-Silva, P.,Carrondo, M.A. (deposition date: 2002-07-12, release date: 2003-07-17, Last modification date: 2023-12-13)
Primary citation	Bonifacio, M.J.,Archer, M.,Rodrigues, M.L.,Matias, P.M.,Learmonth, D.A.,Carrondo, M.A.,Soares-da-Silva, P. Kinetics and Crystal Structure of Catechol-O-Methyltransferase Complex with Co-Substrate and a Novel Inhibitor with Potential Therapeutic Application Mol.Pharmacol., 62:795-, 2002 Cited by PubMed: 12237326 DOI: 10.1124/MOL.62.4.795 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation