PDB: 66478 件ウェブページステータス検索Chemie searchBIRD

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6VOP	Crystal structure of YgbL, a putative aldolase/epimerase/decarboxylase from Escherichia coli 分子名称: Aldolase 著者 Stogios, P.J, Evdokimova, E, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2020-01-31 公開日 2020-02-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Crystal structure of YgbL, a putative aldolase/epimerase/decarboxylase from Escherichia coli To Be Published
6VOQ	Crystal structure of YgbL, a putative aldolase/epimerase/decarboxylase from Klebsiella pneumoniae 分子名称: Aldolase, CHLORIDE ION, ZINC ION 著者 Stogios, P.J, Evdokimova, E, McChesney, C, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2020-01-31 公開日 2020-02-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Crystal structure of YgbL, a putative aldolase/epimerase/decarboxylase from Klebsiella pneumoniae To Be Published
6OFO	Crystal structure of split green fluorescent protein (GFP); s10 circular permutant (194-195) 分子名称: Green fluorescent protein (GFP); s10 circular permutant (194-195) 著者 Lin, C.-Y, Romei, M.G, Deller, M.C, Doukov, T.I, Boxer, S.G. 登録日 2019-03-31 公開日 2019-07-10 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.603 Å) 主引用文献 Unified Model for Photophysical and Electro-Optical Properties of Green Fluorescent Proteins. J.Am.Chem.Soc., 141, 2019
6VPG	TPX2 residues 7-20 fused to Aurora A residues 116-389 in complex with AMP-PNP 分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... 著者 Lim, D.C, Yaffe, M.B. 登録日 2020-02-03 公開日 2020-08-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Redox priming promotes Aurora A activation during mitosis. Sci.Signal., 13, 2020
6OXX	HIV-1 Protease NL4-3 WT in Complex with LR2-18 分子名称: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-4-[({4-[(1R)-1,2-dihydroxyethyl]phenyl}sulfonyl)(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl}carbamate, Protease NL4-3 著者 Lockbaum, G.J, Rusere, L.N, Lee, S.K, Henes, M, Kosovrasti, K, Spielvogel, E, Nalivaika, E.A, Swanstrom, R, KurtYilmaz, N, Schiffer, C.A, Ali, A. 登録日 2019-05-14 公開日 2019-08-21 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.962 Å) 主引用文献 HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope. J.Med.Chem., 62, 2019
6VSX	X-ray crystal structure of the C-terminal domain of Bacillus subtilis RNA polymerase binding helicase HelD 分子名称: DNA helicase, PHOSPHATE ION 著者 Murakami, K.S, Chon, U. 登録日 2020-02-12 公開日 2020-06-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Mycobacterial HelD is a nucleic acids-clearing factor for RNA polymerase. Nat Commun, 11, 2020
6PXQ	Crystal structure of human thrombin mutant D194A 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Thrombin heavy chain, Thrombin light chain 著者 Stojanovski, B, Chen, Z, Koester, S.K, Pelc, L.A, Di Cera, E. 登録日 2019-07-26 公開日 2019-12-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Role of the I16-D194 ionic interaction in the trypsin fold. Sci Rep, 9, 2019
6PTA	Crystal structure of the ARF family small GTPase ARF1 from Candida albicans in complex with GDP 分子名称: ADP-ribosylation factor, GUANOSINE-5'-DIPHOSPHATE 著者 Stogios, P.J, Evdokimova, E, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2019-07-15 公開日 2019-07-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of the ARF family small GTPase ARF1 from Candida albicans in complex with GDP To Be Published
2WQX	InlB321_4R: S199R, D200R, G206R, A227R, C242A mutant of the Listeria monocytogenes InlB internalin domain 分子名称: INTERNALIN B 著者 Niemann, H.H, Ferraris, D.M, Heinz, D.W. 登録日 2009-08-27 公開日 2009-11-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Ligand-Mediated Dimerization of the met Receptor Tyrosine Kinase by the Bacterial Invasion Protein Inlb. J.Mol.Biol., 395, 2010
6Q2K	The structure of the Streptococcus gordonii surface protein SspB in complex with TEV peptide provides clues to the adherence of oral streptococcal adherence to salivary agglutinin 分子名称: Agglutinin receptor, CALCIUM ION 著者 Schormann, N, Deivanayagam, C. 登録日 2019-08-08 公開日 2020-08-12 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The structure of the Streptococcus gordonii surface protein SspB in complex with TEV peptide provides clues to the adherence of oral streptococcal adherence to salivary agglutinin To Be Published
1YH2	Ubiquitin-Conjugating Enzyme HSPC150 分子名称: HSPC150 protein similar to ubiquitin-conjugating enzyme 著者 Walker, J.R, Avvakumov, G.V, Newman, E.M, Mackenzie, F, Kozieradzki, I, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-paganon, S, Structural Genomics Consortium (SGC) 登録日 2005-01-06 公開日 2005-02-15 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen. Mol Cell Proteomics, 11, 2012
6Q1P	Glucocerebrosidase in complex with pharmacological chaperone norIMX8 分子名称: (2S,3S,4S,5R)-2-{[(4-methylpentyl)sulfonyl]methyl}piperidine-3,4,5-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Vickers, C, Withers, S.G, Boraston, A.B. 登録日 2019-08-05 公開日 2020-08-19 実験手法 X-RAY DIFFRACTION (2.796 Å) 主引用文献 Pharmacological chaperones for GCase that switch conformation with pH enhance enzyme levels in Gaucher animal models. To Be Published
6VPB	A novel membrane-bound 6-phosphogluconate dehydrogenase from the acetic acid bacteria Gluconacetobacter diazotrophicus (Gd6PGD) 分子名称: 6-phosphogluconate dehydrogenase, DI(HYDROXYETHYL)ETHER, ISOPROPYL ALCOHOL, ... 著者 Rodriguez-Romero, A, Rodriguez-Hernandez, A. 登録日 2020-02-02 公開日 2020-07-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 The structure of a novel membrane-associated 6-phosphogluconate dehydrogenase from Gluconacetobacter diazotrophicus (Gd6PGD) reveals a subfamily of short-chain 6PGDs. Febs J., 288, 2021
6OPU	HIV-1 Protease NL4-3 K45I, M46I, V82F, I84V Mutant in complex with darunavir 分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, Protease NL4-3 著者 Lockbaum, G.J, Henes, M, Kosovrasti, K, Leidner, F, Nachum, G.S, Nalivaika, E.A, Bolon, D.N.A, KurtYilmaz, N, Schiffer, C.A. 登録日 2019-04-25 公開日 2019-09-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Picomolar to Micromolar: Elucidating the Role of Distal Mutations in HIV-1 Protease in Conferring Drug Resistance. Acs Chem.Biol., 14, 2019
6OIE	The double PHD finger (DPF) of MORF in complex with histone H3K14cr 分子名称: Histone H3.1t peptide, Histone acetyltransferase KAT6B, ZINC ION 著者 Klein, B.J, Kutateladze, T.G. 登録日 2019-04-09 公開日 2019-11-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.075 Å) 主引用文献 Histone H3K23-specific acetylation by MORF is coupled to H3K14 acylation. Nat Commun, 10, 2019
6OXQ	HIV-1 Protease NL4-3 WT in Complex with UMass8 分子名称: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(1S,2R)-1-benzyl-3-[(2-ethylbutyl){[4-(hydroxymethyl)phenyl]sulfonyl}amino]-2-hydroxypropyl}carbamate, Protease NL4-3, SULFATE ION 著者 Lockbaum, G.J, Rusere, L.N, Lee, S.K, Henes, M, Kosovrasti, K, Spielvogel, E, Nalivaika, E.A, Swanstrom, R, KurtYilmaz, N, Schiffer, C.A, Ali, A. 登録日 2019-05-14 公開日 2019-08-21 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope. J.Med.Chem., 62, 2019
6OXV	HIV-1 Protease NL4-3 WT in Complex with LR-85 分子名称: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-4-[(2-ethylbutyl)({4-[(1S)-1-hydroxyethyl]phenyl}sulfonyl)amino]-3-hydroxy-1-phenylbutan-2-yl}carbamate, Protease NL4-3 著者 Lockbaum, G.J, Rusere, L.N, Lee, S.K, Henes, M, Kosovrasti, K, Spielvogel, E, Nalivaika, E.A, Swanstrom, R, KurtYilmaz, N, Schiffer, C.A, Ali, A. 登録日 2019-05-14 公開日 2019-08-21 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.991 Å) 主引用文献 HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope. J.Med.Chem., 62, 2019
6OYG	Crystal structure of H62F mutant of human macrophage migration inhibitory factor 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... 著者 Pantouris, G, Lolis, E. 登録日 2019-05-14 公開日 2020-04-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Regulation of MIF Enzymatic Activity by an Allosteric Site at the Central Solvent Channel. Cell Chem Biol, 27, 2020
6OVJ	NMR structure of truncated alpha conotoxin SII: Ile-SII(3-14) 分子名称: Alpha-conotoxin S2 著者 Chin, Y.K.-Y, Wilhelm, P, Alewood, P.F. 登録日 2019-05-08 公開日 2020-05-06 最終更新日 2023-10-11 実験手法 SOLUTION NMR 主引用文献 Cysteine-Rich alpha-Conotoxin SII Displays Novel Interactions at the Muscle Nicotinic Acetylcholine Receptor. Acs Chem Neurosci, 13, 2022
6OXY	HIV-1 Protease NL4-3 WT in Complex with LR2-19 分子名称: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-4-[({4-[(1S)-1,2-dihydroxyethyl]phenyl}sulfonyl)(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl}carbamate, Protease NL4-3, SULFATE ION 著者 Lockbaum, G.J, Rusere, L.N, Lee, S.K, Henes, M, Kosovrasti, K, Spielvogel, E, Nalivaika, E.A, Swanstrom, R, KurtYilmaz, N, Schiffer, C.A, Ali, A. 登録日 2019-05-14 公開日 2019-08-21 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope. J.Med.Chem., 62, 2019
6OY8	Crystal structure of Y99G mutant of human macrophage migration inhibitory factor 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... 著者 Pantouris, G, Lolis, E. 登録日 2019-05-14 公開日 2020-04-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Regulation of MIF Enzymatic Activity by an Allosteric Site at the Central Solvent Channel. Cell Chem Biol, 27, 2020
6OL4	Protein Tyrosine Phosphatase 1B (1-301), F182A mutant, apo state 分子名称: GLYCEROL, Tyrosine-protein phosphatase non-receptor type 1 著者 Cui, D.S, Lipchock, J.M, Loria, J.P. 登録日 2019-04-15 公開日 2020-03-25 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Uncovering the Molecular Interactions in the Catalytic Loop That Modulate the Conformational Dynamics in Protein Tyrosine Phosphatase 1B. J.Am.Chem.Soc., 141, 2019
6OOU	Crystal structure of HIV-1 Protease NL4-3 L89V Mutant in complex with darunavir 分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, NL4-3 PROTEASE, SULFATE ION 著者 Henes, M, Kosovrasti, K, Lockbaum, G.J, Leidner, F, Nachum, G.S, Nalivaika, E.A, Bolon, D.N.A, KurtYilmaz, N, Schiffer, C.A, Whitfield, T.W. 登録日 2019-04-23 公開日 2019-08-21 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.127 Å) 主引用文献 Molecular Determinants of Epistasis in HIV-1 Protease: Elucidating the Interdependence of L89V and L90M Mutations in Resistance. Biochemistry, 58, 2019
6O56	HNH Nuclease from S. pyogenes Cas9 分子名称: CRISPR-associated endonuclease Cas9/Csn1 著者 Newton, J.C, Lisi, G.P, Jogl, G. 登録日 2019-03-01 公開日 2020-01-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Allosteric Motions of the CRISPR-Cas9 HNH Nuclease Probed by NMR and Molecular Dynamics. J.Am.Chem.Soc., 142, 2020
6O62	Crystal structure of Sec4p, a Rab family GTPase from Candida albicans 分子名称: GUANOSINE-5'-DIPHOSPHATE, Ras-related protein SEC4 著者 Stogios, P.J, Skarina, T, Di Leo, R, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2019-03-05 公開日 2019-04-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 To be published To Be Published

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