6O56
HNH Nuclease from S. pyogenes Cas9
Summary for 6O56
| Entry DOI | 10.2210/pdb6o56/pdb |
| Descriptor | CRISPR-associated endonuclease Cas9/Csn1 (2 entities in total) |
| Functional Keywords | nuclease, crispr cas9, dna binding protein |
| Biological source | Streptococcus pyogenes serotype M1 |
| Total number of polymer chains | 2 |
| Total formula weight | 31970.09 |
| Authors | Newton, J.C.,Lisi, G.P.,Jogl, G. (deposition date: 2019-03-01, release date: 2020-01-15, Last modification date: 2023-10-11) |
| Primary citation | East, K.W.,Newton, J.C.,Morzan, U.N.,Narkhede, Y.B.,Acharya, A.,Skeens, E.,Jogl, G.,Batista, V.S.,Palermo, G.,Lisi, G.P. Allosteric Motions of the CRISPR-Cas9 HNH Nuclease Probed by NMR and Molecular Dynamics. J.Am.Chem.Soc., 142:1348-1358, 2020 Cited by PubMed: 31885264DOI: 10.1021/jacs.9b10521 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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