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4QL7
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Crystal structure of C-terminus truncated Alkylhydroperoxide Reductase subunit C (AhpC1-172) from E. coli
分子名称: Alkylhydroperoxide Reductase subunit C
著者Kamariah, N, Gruber, G, Eisenhaber, F, Eisenhaber, B.
登録日2014-06-11
公開日2014-09-24
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (3.75 Å)
主引用文献Key roles of the Escherichia coli AhpC C-terminus in assembly and catalysis of alkylhydroperoxide reductase, an enzyme essential for the alleviation of oxidative stress.
Biochim.Biophys.Acta, 1837, 2014
4QL9
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Crystal structure of C-terminus truncated Alkylhydroperoxide Reductase subunit C (AhpC1-182) from E. coli
分子名称: Alkylhydroperoxide Reductase subunit C
著者Nartey, W, Kamariah, N, Gruber, G.
登録日2014-06-11
公開日2014-09-24
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Key roles of the Escherichia coli AhpC C-terminus in assembly and catalysis of alkylhydroperoxide reductase, an enzyme essential for the alleviation of oxidative stress.
Biochim.Biophys.Acta, 1837, 2014
1RJH
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Structure of the Calcium Free Form of the C-type Lectin-like Domain of Tetranectin
分子名称: Tetranectin
著者Nielbo, S, Thomsen, J.K, Graversen, J.H, Etzerodt, M, Poulsen, F.M, Thoegersen, H.C.
登録日2003-11-19
公開日2004-07-20
最終更新日2024-10-16
実験手法SOLUTION NMR
主引用文献Structure of the Plasminogen Kringle 4 Binding Calcium-Free Form of the C-Type Lectin-Like Domain of Tetranectin.
Biochemistry, 43, 2004
6LBG
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Structure of OR51B2 bound FEM1C
分子名称: Protein fem-1 homolog C,Peptide from Olfactory receptor 51B2, SULFATE ION
著者Chen, X, Liao, S, Xu, C.
登録日2019-11-14
公開日2020-10-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
5TRG
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Structure of Mycobacterium tuberculosis proteasome in complex with N,C-capped dipeptide DPLG-2
分子名称: N,N-diethyl-N~2~-[(2E)-3-phenylprop-2-enoyl]-L-asparaginyl-4-fluoro-N-[(naphthalen-1-yl)methyl]-L-phenylalaninamide, Proteasome subunit alpha, Proteasome subunit beta
著者Hsu, H.-C, Fan, H, Singh, R.K, Wang, R, Sukenick, G, Nathan, C, Lin, G, Li, H.
登録日2016-10-26
公開日2017-01-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.804 Å)
主引用文献Structural Basis for the Species-Selective Binding of N,C-Capped Dipeptides to the Mycobacterium tuberculosis Proteasome.
Biochemistry, 56, 2017
6LE6
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Structure of LNLPTQGRAR bound FEM1C
分子名称: Protein fem-1 homolog C,10-mer peptide, SULFATE ION
著者Chen, X, Liao, S, Xu, C.
登録日2019-11-24
公開日2020-10-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
2TN4
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FOUR CALCIUM TNC
分子名称: CALCIUM ION, TROPONIN C
著者Love, M.L, Dominguez, R, Houdusse, A, Cohen, C.
登録日1997-09-18
公開日1998-04-08
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of four Ca2+-bound troponin C at 2.0 A resolution: further insights into the Ca2+-switch in the calmodulin superfamily.
Structure, 5, 1997
3CJ0
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BU of 3cj0 by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with small molecule fragments
分子名称: 4-[(5-bromopyridin-2-yl)amino]-4-oxobutanoic acid, RNA-directed RNA polymerase
著者Kissinger, c.
登録日2008-03-12
公開日2008-04-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
1ERJ
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CRYSTAL STRUCTURE OF THE C-TERMINAL WD40 DOMAIN OF TUP1
分子名称: TRANSCRIPTIONAL REPRESSOR TUP1
著者Sprague, E.R, Redd, M.J, Johnson, A.D, Wolberger, C.
登録日2000-04-06
公開日2000-07-26
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the C-terminal domain of Tup1, a corepressor of transcription in yeast.
EMBO J., 19, 2000
2AX1
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Hepatitis C Virus NS5b RNA Polymerase in complex with a covalent inhibitor (5ee)
分子名称: 5R-(3,4-DICHLOROPHENYLMETHYL)-3-(2-THIOPHENESULFONYLAMINO)-4-OXO-2-THIONOTHIAZOLIDINE, Genome polyprotein, SULFATE ION
著者Powers, J.P, Piper, D.E, Li, Y, Mayorga, V, Anzola, J, Chen, J.M, Jaen, J.C, Lee, G, Liu, J, Peterson, M.G, Tonn, G.R, Ye, Q, Walker, N.P, Wang, Z.
登録日2005-09-02
公開日2006-01-24
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献SAR and Mode of Action of Novel Non-Nucleoside Inhibitors of Hepatitis C NS5b RNA Polymerase.
J.Med.Chem., 49, 2006
3CJ3
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Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
分子名称: 4-bromo-2-{[(2R)-2-(2-chlorobenzyl)pyrrolidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase
著者Kissinger, c.
登録日2008-03-12
公開日2008-04-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
3CJ2
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Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
分子名称: 4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase
著者Kissinger, c.
登録日2008-03-12
公開日2008-04-15
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
2EDN
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BU of 2edn by Molmil
Solution structure of the first ig-like domain from human Myosin-binding protein C, fast-type
分子名称: Myosin-binding protein C, fast-type
著者Nagashima, K, Kurosaki, C, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-02-14
公開日2007-08-14
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the first ig-like domain from human Myosin-binding protein C, fast-type
To be Published
2VIF
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BU of 2vif by Molmil
Crystal structure of SOCS6 SH2 domain in complex with a c-KIT phosphopeptide
分子名称: 1,2-ETHANEDIOL, MAST/STEM CELL GROWTH FACTOR RECEPTOR, SUPPRESSOR OF CYTOKINE SIGNALLING 6
著者Bullock, A, Pike, A.C.W, Savitsky, P, Keates, T, Pilka, E.S, von Delft, F, Edwards, A, Weigelt, J, Arrowsmith, C.H, Knapp, S.
登録日2007-11-30
公開日2007-12-25
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural Basis for C-Kit Inhibition by the Suppressor of Cytokine Signaling 6 (Socs6) Ubiquitin Ligase.
J.Biol.Chem., 286, 2011
7CLZ
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Crystal structure of Alp1U W187F/Y247F in complex with fluostatin C
分子名称: BORIC ACID, D-MALATE, Fluostatin C, ...
著者Zhang, L, De, B.C.
登録日2020-07-22
公開日2020-10-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.10001016 Å)
主引用文献Mutation of an atypical oxirane oxyanion hole improves regioselectivity of the alpha / beta-fold epoxide hydrolase Alp1U.
J.Biol.Chem., 295, 2020
1H4J
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Methylobacterium extorquens methanol dehydrogenase D303E mutant
分子名称: CALCIUM ION, Methanol dehydrogenase [cytochrome c] subunit 1, Methanol dehydrogenase [cytochrome c] subunit 2, ...
著者Mohammed, F, Gill, R, Thompson, D, Cooper, J.B, Wood, S.P, Afolabi, P.R, Anthony, C.
登録日2001-05-11
公開日2001-08-23
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Site-Directed Mutagenesis and X-Ray Crystallography of the Pqq-Containing Quinoprotein Methanol Dehydrogenase and its Electron Acceptor, Cytochrome C(L)(,)
Biochemistry, 40, 2001
2QEE
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BU of 2qee by Molmil
Crystal structure of putative amidohydrolase BH0493 from Bacillus halodurans C-125
分子名称: BH0493 protein, CHLORIDE ION, MAGNESIUM ION, ...
著者Malashkevich, V.N, Toro, R, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-06-25
公開日2007-07-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of putative amidohydrolase BH0493 from Bacillus halodurans C-125.
To be Published
2AWZ
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BU of 2awz by Molmil
Hepatitis C Virus NS5b RNA Polymerase in complex with a covalent inhibitor (5h)
分子名称: 5R-(4-BROMOPHENYLMETHYL)-3-(BENZENESULFONYLAMINO)-4-OXO-2-THIONOTHIAZOLIDINE, Genome polyprotein, SULFATE ION
著者Powers, J.P, Piper, D.E, Li, Y, Mayorga, V, Anzola, J, Chen, J.M, Jaen, J.C, Lee, G, Liu, J, Peterson, M.G, Tonn, G.R, Ye, Q, Walker, N.P, Wang, Z.
登録日2005-09-02
公開日2006-01-24
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献SAR and Mode of Action of Novel Non-Nucleoside Inhibitors of Hepatitis C NS5b RNA Polymerase.
J.Med.Chem., 49, 2006
3QGH
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Crystal structure of the hepatitis C virus NS5B RNA-dependent RNA polymerase genotype 1a complex with N-cyclopropyl-6-[(3R)-3-{[4-(trifluoromethoxy)benzyl]carbamoyl}-4-{[4-(trifluoromethoxy)phenyl]sulfonyl}piperazin-1-yl]pyridazine-3-carboxamide
分子名称: N-cyclopropyl-6-[(3R)-3-{[4-(trifluoromethoxy)benzyl]carbamoyl}-4-{[4-(trifluoromethoxy)phenyl]sulfonyl}piperazin-1-yl]pyridazine-3-carboxamide, PHOSPHATE ION, RNA-directed RNA polymerase
著者Sheriff, S.
登録日2011-01-24
公開日2011-04-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Investigation of the mode of binding of a novel series of N-benzyl-4-heteroaryl-1-(phenylsulfonyl)piperazine-2-carboxamides to the hepatitis C virus polymerase.
Bioorg.Med.Chem.Lett., 21, 2011
3SS3
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Crystal structure of mouse Glutaminase C, ligand-free form
分子名称: CHLORIDE ION, Glutaminase C
著者Ambrosio, A.L.B, Dias, S.M.G, Cerione, R.A.
登録日2011-07-07
公開日2012-01-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
2JDL
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Structure of C-terminal region of acidic P2 ribosomal protein complexed with trichosanthin
分子名称: ACIDIC RIBOSOMAL PROTEIN P2, RIBOSOME-INACTIVATING PROTEIN ALPHA-TRICHOSANTHIN
著者Too, P.H, Mak, A.N, Zhu, G, Au, S.W, Wong, K.B, Shaw, P.C.
登録日2007-01-11
公開日2008-02-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The C-Terminal Fragment of the Ribosomal P Protein Complexed to Trichosanthin Reveals the Interaction between the Ribosome-Inactivating Protein and the Ribosome.
Nucleic Acids Res., 37, 2009
3SS5
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Crystal structure of mouse Glutaminase C, L-glutamate-bound form
分子名称: GLUTAMIC ACID, Glutaminase C
著者Ambrosio, A.L.B, Dias, S.M.G, Cerione, R.A.
登録日2011-07-07
公開日2012-01-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
1H3M
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Structure of 4-diphosphocytidyl-2C-methyl-D-erythritol synthetase
分子名称: 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CHLORIDE ION, PENTANE-1,5-DIAMINE
著者Kemp, L.E, Bond, C.S, Hunter, W.N.
登録日2002-09-10
公開日2003-08-01
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of a Tetragonal Crystal Form of Escherichia Coli 2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase
Acta Crystallogr.,Sect.D, 59, 2003
3PYD
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crystal structure of 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (IspE) from Mycobacterium tuberculosis
分子名称: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, GLYCEROL
著者Shan, S, Chen, X.H, Liu, T, Zhao, H.C, Rao, Z.H, Lou, Z.Y.
登録日2010-12-13
公開日2012-01-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献The Structural Basis for anti-TB Drug Discovery targeting of 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (IspE) from Mycobacterium tuberculosis
To be Published
1HEI
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STRUCTURE OF THE HEPATITIS C VIRUS RNA HELICASE DOMAIN
分子名称: CALCIUM ION, HCV HELICASE
著者Yao, N, Weber, P.
登録日1997-03-31
公開日1998-10-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of the hepatitis C virus RNA helicase domain.
Nat.Struct.Biol., 4, 1997

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