PDB: 66212 件ウェブページステータス検索Chemie searchBIRD

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6CZN	Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Z2OHTPE and a glucocorticoid receptor-interacting protein 1 NR box II peptide 分子名称: 4,4'-[(1R,2R)-1-phenylbutane-1,2-diyl]diphenol, Estrogen receptor, GRIP Peptide 著者 Fanning, S.W, Han, R, Maximov, P, Jordan, V.C, Greene, G.L. 登録日 2018-04-09 公開日 2019-03-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Z2OHTPE and a glucocorticoid receptor-interacting protein 1 NR box II peptide To Be Published
3PQC	Crystal structure of Thermotoga maritima ribosome biogenesis GTP-binding protein EngB (YsxC/YihA) in complex with GDP 分子名称: DI(HYDROXYETHYL)ETHER, GUANOSINE-5'-DIPHOSPHATE, Probable GTP-binding protein engB 著者 Chan, K.H, Wong, K.B. 登録日 2010-11-26 公開日 2011-06-08 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of an essential GTPase, YsxC, from Thermotoga maritima Acta Crystallogr.,Sect.F, 67, 2011
3PR1	Crystal structure of apo Thermotoga maritima ribosome biogenesis GTP-binding protein EngB 分子名称: PHOSPHATE ION, Probable GTP-binding protein engB 著者 Chan, K.H, Wong, K.B. 登録日 2010-11-29 公開日 2011-06-08 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of an essential GTPase, YsxC, from Thermotoga maritima Acta Crystallogr.,Sect.F, 67, 2011
2YBS	JMJD2A COMPLEXED WITH S-2-HYDROXYGLUTARATE AND HISTONE H3K36me3 PEPTIDE (30-41) 分子名称: (2S)-2-HYDROXYPENTANEDIOIC ACID, GLYCEROL, HISTONE H3.1T, ... 著者 Chowdhury, R, Schofield, C.J. 登録日 2011-03-10 公開日 2011-03-30 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases. EMBO Rep., 12, 2011
6ITK	Crystal structure of malate dehydrogenase from Corynebacterium glutamicum ATCC 13032 in complex with NAD and malate 分子名称: (2S)-2-hydroxybutanedioic acid, Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Seo, H, Kim, K.-J. 登録日 2018-11-23 公開日 2019-11-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Enhanced succinic acid production by Mannheimia employing optimal malate dehydrogenase. Nat Commun, 11, 2020
2QCL	Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to OMP 分子名称: GLYCEROL, OROTIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase (UMP synthase) 著者 Wittmann, J, Rudolph, M. 登録日 2007-06-19 公開日 2007-11-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure, 16, 2008
2QCC	Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase, apo form 分子名称: GLYCEROL, Orotidine 5'- phosphate decarboxylase (OMPdecase), SULFATE ION 著者 Wittmann, J, Rudolph, M. 登録日 2007-06-19 公開日 2007-11-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure, 16, 2008
2QCM	Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 6-hydroxymethyl-UMP 分子名称: 6-(HYDROXYMETHYL)URIDINE 5'-(DIHYDROGEN PHOSPHATE), Uridine 5'-monophosphate synthase (UMP synthase) 著者 Wittmann, J, Rudolph, M. 登録日 2007-06-19 公開日 2007-11-06 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure, 16, 2008
3FYO	Crystal structure of the triple mutant (N23C/D247E/P249A) of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis 分子名称: 3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase, CHLORIDE ION, MANGANESE (II) ION, ... 著者 Jameson, G.B, Parker, E.J, Cochrane, F.P, Patchett, M.L. 登録日 2009-01-22 公開日 2009-03-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Reversing evolution: re-establishing obligate metal ion dependence in a metal-independent KDO8P synthase J.Mol.Biol., 390, 2009
2QCH	Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to 5-iodo-UMP 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-IODO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, IODIDE ION, ... 著者 Wittmann, J, Rudolph, M. 登録日 2007-06-19 公開日 2007-11-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure, 16, 2008
3FYP	Crystal structure of the quadruple mutant (N23C/C246S/D247E/P249A) of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis 分子名称: 3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase, CHLORIDE ION, GLYCEROL, ... 著者 Jameson, G.B, Parker, E.J, Cochrane, F.P, Patchett, M.L. 登録日 2009-01-22 公開日 2009-03-31 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Reversing evolution: re-establishing obligate metal ion dependence in a metal-independent KDO8P synthase J.Mol.Biol., 390, 2009
2QCN	Covalent complex of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase with 6-iodo-UMP 分子名称: GLYCEROL, SULFATE ION, URIDINE-5'-MONOPHOSPHATE, ... 著者 Wittmann, J, Rudolph, M. 登録日 2007-06-19 公開日 2007-11-13 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure, 16, 2008
6UVD	Crystal structure of BCL-XL bound to compound 2: (2R)-3-(Benzylsulfanyl)-2-({[(4-methylphenyl)methyl] [(4 phenylphenyl)carbonyl] carbamoyl}amino) propanoic acid 分子名称: (2R)-3-(Benzylsulfanyl)-2-({[(4-methylphenyl)methyl] [(4 phenylphenyl)carbonyl] carbamoyl}amino) propanoic acid, 1,2-ETHANEDIOL, Bcl-2-like protein 1, ... 著者 Roy, M.J, Birkinshaw, R, Lessene, G, Czabotar, P.E. 登録日 2019-11-02 公開日 2021-05-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structure-Guided Development of Potent Benzoylurea Inhibitors of BCL-X L and BCL-2. J.Med.Chem., 64, 2021
2UUY	Structure of a tick tryptase inhibitor in complex with bovine trypsin 分子名称: CALCIUM ION, CATIONIC TRYPSIN, CHLORIDE ION, ... 著者 Siebold, C, Paesen, G.C, Harlos, K, Peacey, M.F, Nuttall, P.A, Stuart, D.I. 登録日 2007-03-08 公開日 2007-04-10 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 A Tick Protein with a Modified Kunitz Fold Inhibits Human Tryptase. J.Mol.Biol., 368, 2007
2QCD	Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to UMP 分子名称: URIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase (UMP synthase) 著者 Wittmann, J, Rudolph, M. 登録日 2007-06-19 公開日 2007-11-06 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure, 16, 2008
6PRD	S. aureus dihydrofolate reductase co-crystallized with para-methoxyphenyl-dimethyoxydihydropthalazine inhibitor and NADP(H) 分子名称: 3-{5-[(2,4-diaminopyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}-1-[(1S)-6,7-dimethoxy-1-(4-methoxyphenyl)-3,4-dihydrophthalazin-2(1H)-yl]propan-1-one, Dihydrofolate reductase, GLYCEROL, ... 著者 Bourne, C.R, Thomas, L.M. 登録日 2019-07-10 公開日 2020-06-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Inhibitor design to target a unique feature in the folate pocket of Staphylococcus aureus dihydrofolate reductase. Eur.J.Med.Chem., 200, 2020
2VPR	Tet repressor class H in complex with 5a,6- anhydrotetracycline-Mg 分子名称: 5A,6-ANHYDROTETRACYCLINE, MAGNESIUM ION, SULFATE ION, ... 著者 Schuldt, L, Palm, G, Hinrichs, W. 登録日 2008-03-03 公開日 2008-03-11 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Tet Repressor Induction by Tetracycline: A Molecular Dynamics, Continuum Electrostatics, and Crystallographic Study J.Mol.Biol., 378, 2008
3LGU	Y162A mutant of the DegS-deltaPDZ protease 分子名称: Protease degS 著者 Sohn, J, Grant, R.A, Sauer, R.T. 登録日 2010-01-21 公開日 2010-08-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution. J.Biol.Chem., 285, 2010
3FC0	1.8 A crystal structure of murine GITR ligand dimer expressed in Drosophila melanogaster S2 cells 分子名称: ACETATE ION, GITR ligand 著者 Chattopadhyay, K, Ramagopal, U.A, Nathenson, S.G, Almo, S.C. 登録日 2008-11-20 公開日 2008-12-30 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 1.8 A structure of murine GITR ligand dimer expressed in Drosophila melanogaster S2 cells. Acta Crystallogr.,Sect.D, 65, 2009
9EOQ	Cryo-EM Structure of a 1033 Scaffold Base DNA Origami Nanostructure V4 and TBA 分子名称: DNA (42-MER), DNA (5'-D(P*AP*TP*AP*TP*AP*GP*CP*GP*TP*GP*GP*AP*AP*GP*T)-3') 著者 Ali, K, Georg, K, Volodymyr, M, Johanna, G, Maximilian, N.H, Lukas, K, Simone, C, Hendrik, D. 登録日 2024-03-15 公開日 2024-04-24 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (7.5 Å) 主引用文献 Designing Rigid DNA Origami Templates for Molecular Visualization Using Cryo-EM. Nano Lett., 24, 2024
3LGT	Y162A/H198P double mutant of DegS-deltaPDZ protease 分子名称: Protease degS 著者 Sohn, J, Grant, R.A, Sauer, R.T. 登録日 2010-01-21 公開日 2010-08-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution. J.Biol.Chem., 285, 2010
8FAV	HUMAN RETENOID-RELATED ORPHAN RECEPTOR-GAMMA (RORC2) LIGAND-BINDING DOMAIN IN COMPLEX WITH COMPOUND 5 ANDINDAZOLE ACID BOUND IN H12-POCKET 分子名称: 3-cyano-N-(3-{[(3S)-4-(cyclopentanecarbonyl)-3-methylpiperazin-1-yl]methyl}-5-fluoro-2-methylphenyl)benzamide, 4-{1-[2-chloro-6-(trifluoromethyl)benzoyl]-4-fluoro-1H-indazol-3-yl}-3-fluorobenzoic acid, Nuclear receptor ROR-gamma, ... 著者 Vajdos, F.F. 登録日 2022-11-28 公開日 2023-03-01 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Macrocyclic Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonists. Acs Med.Chem.Lett., 14, 2023
6OFK	Crystal structure of green fluorescent protein (GFP); S65T; ih circular permutant (50-51) 分子名称: ACETATE ION, Green Fluorescent Protein (GFP); S65T; ih circular permutant (50-51) 著者 Lin, C.-Y, Romei, M.G, Mathews, I.I, Boxer, S.G. 登録日 2019-03-30 公開日 2019-07-10 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Unified Model for Photophysical and Electro-Optical Properties of Green Fluorescent Proteins. J.Am.Chem.Soc., 141, 2019
4UHV	The structure of VgrG1, the needle tip of the bacterial Type VI Secretion System 分子名称: CHLORIDE ION, SODIUM ION, VGRG1, ... 著者 Spinola-Amilibia, M, Davo-Siguero, I, Ruiz, F.M, Santillana, E, Medrano, F.J, Romero, A. 登録日 2015-03-25 公開日 2016-01-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The Structure of Vgrg1 from Pseudomonas Aeruginosa, the Needle Tip of the Bacterial Type Vi Secretion System Acta Crystallogr.,Sect.D, 72, 2016
5BRZ	MAGE-A3 reactive TCR in complex with MAGE-A3 in HLA-A1 分子名称: Beta-2-microglobulin, GLU-VAL-ASP-PRO-ILE-GLY-HIS-LEU-TYR, HLA class I histocompatibility antigen, ... 著者 Raman, M.C.C, Rizkallah, P.J, Simmons, R, Donnellan, Z, Dukes, J, Bossi, G, LeProvost, G, Mahon, T, Hickman, E, LomaX, M, Oates, J, Hassan, N, Vuidepot, A, Sami, M, Cole, D.K, Jakobsen, B.K. 登録日 2015-06-01 公開日 2016-03-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy. Sci Rep, 6, 2016

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