PDB: 2849 件ウェブページステータス検索Chemie searchBIRD

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8I5N	Rat Kir4.1 in complex with PIP2 and Lys05 分子名称: ATP-sensitive inward rectifier potassium channel 10, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate 著者 Zhao, C, Guo, J. 登録日 2023-01-26 公開日 2024-02-28 実験手法 ELECTRON MICROSCOPY (2.85 Å) 主引用文献 Pharmacological inhibition of astrocytic Kir4.1 channel evokes rapid-onset antidepressant responses To Be Published
6PBY	Single particle cryo-EM structure of the voltage-gated K+ channel Eag1 3-13 deletion mutant bound to calmodulin (conformation 1) 分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1 著者 Whicher, J.R, MacKinnon, R. 登録日 2019-06-14 公開日 2019-09-18 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.67 Å) 主引用文献 Regulation of Eag1 gating by its intracellular domains. Elife, 8, 2019
6PBX	Single particle cryo-EM structure of the voltage-gated K+ channel Eag1 3-13 deletion mutant bound to calmodulin (conformation 2) 分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1 著者 Whicher, J.R, MacKinnon, R. 登録日 2019-06-14 公開日 2019-09-18 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Regulation of Eag1 gating by its intracellular domains. Elife, 8, 2019
7TCI	Structure of Xenopus KCNQ1-CaM in complex with ML277 分子名称: (2R)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylbenzene-1-sulfonyl)piperidine-2-carboxamide, CALCIUM ION, Calmodulin-1, ... 著者 Willegems, K, Kyriakis, E, Van Petegem, F, Eldstrom, J, Fedida, D. 登録日 2021-12-23 公開日 2022-07-06 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural and electrophysiological basis for the modulation of KCNQ1 channel currents by ML277. Nat Commun, 13, 2022
7TCP	Structure of Xenopus KCNQ1-CaM 分子名称: CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 1 著者 Willegems, K, Kyriakis, E, Van Petegem, F, Eldstrom, J, Fedida, D. 登録日 2021-12-27 公開日 2022-07-06 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (3.84 Å) 主引用文献 Structural and electrophysiological basis for the modulation of KCNQ1 channel currents by ML277. Nat Commun, 13, 2022
1JLZ	Solution Structure of a K+-Channel Blocker from the Scorpion Toxin of Tityus cambridgei 分子名称: Tityustoxin alpha-KTx 著者 Wang, I, Wu, S.-H, Chang, H.-K, Shieh, R.-C, Yu, H.-M, Chen, C. 登録日 2001-07-17 公開日 2002-02-06 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 Solution structure of a K(+)-channel blocker from the scorpion Tityus cambridgei. Protein Sci., 11, 2002
6PZB	Cryo-EM structure of the pancreatic beta-cell SUR1 Apo state 分子名称: ATP-binding cassette sub-family C member 8 著者 Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W. 登録日 2019-07-31 公開日 2019-08-14 最終更新日 2020-10-07 実験手法 ELECTRON MICROSCOPY (4.55 Å) 主引用文献 Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM. Elife, 8, 2019
6PZI	Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP only 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8 著者 Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W. 登録日 2019-07-31 公開日 2019-08-14 最終更新日 2020-10-07 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM. Elife, 8, 2019
5MRW	Structure of the KdpFABC complex 分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, POTASSIUM ION, Potassium-transporting ATPase ATP-binding subunit, ... 著者 Huang, C, Pedersen, B.P, Stokes, D.L. 登録日 2016-12-27 公開日 2017-06-21 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structure of the potassium-importing KdpFABC membrane complex. Nature, 546, 2017
6IYX	Crystal Structure Analysis of a Eukaryotic Membrane Protein 分子名称: BROMIDE ION, CALCIUM ION, Trimeric intracellular cation channel type A 著者 Zeng, Y, Wang, X.H, Gao, F, Su, M, Chen, Y.H. 登録日 2018-12-17 公開日 2019-05-01 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis for activity of TRIC counter-ion channels in calcium release. Proc.Natl.Acad.Sci.USA, 116, 2019
6IZ5	Crystal Structure Analysis of a Eukaryotic Membrane Protein 分子名称: Trimeric intracellular cation channel type B-B 著者 Li, D, Su, M, Hendrickson, W.A, Chen, Y.H. 登録日 2018-12-18 公開日 2019-05-01 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.701 Å) 主引用文献 Structural basis for activity of TRIC counter-ion channels in calcium release. Proc.Natl.Acad.Sci.USA, 116, 2019
8WUI	SKOR D312N L271P double mutation 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Potassium channel SKOR 著者 Gao, X, Sun, T, Lu, Y, Jia, Y, Xu, X, Zhang, Y, Fu, P, Yang, G. 登録日 2023-10-20 公開日 2024-04-10 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural changes in the conversion of an Arabidopsis outward-rectifying K + channel into an inward-rectifying channel. Plant Commun., 5, 2024
3WFN	Crystal Structure of Nav1.6 IQ motif in complex with apo-CaM 分子名称: Calmodulin, Sodium channel protein type 8 subunit alpha 著者 Chichili, V.P.R, Sivaraman, J. 登録日 2013-07-23 公開日 2013-08-28 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural Basis for the Modulation of the Neuronal Voltage-Gated Sodium Channel NaV1.6 by Calmodulin Sci Rep, 3, 2013
6WEJ	Structure of cGMP-unbound WT TAX-4 reconstituted in lipid nanodiscs 分子名称: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cyclic nucleotide-gated cation channel, ... 著者 Zheng, X, Fu, Z, Su, D, Zhang, Y, Li, M, Pan, Y, Li, H, Li, S, Grassucci, R.A, Ren, Z, Hu, Z, Li, X, Zhou, M, Li, G, Frank, J, Yang, J. 登録日 2020-04-02 公開日 2020-06-03 最終更新日 2020-07-22 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Mechanism of ligand activation of a eukaryotic cyclic nucleotide-gated channel. Nat.Struct.Mol.Biol., 27, 2020
1JPQ	Crystal Structure of the Oxytricha Telomeric DNA at 1.6A 分子名称: 5'-D(*GP*GP*GP*GP*(BRU)P*TP*TP*TP*GP*GP*GP*G)-3', POTASSIUM ION 著者 Haider, S.M, Parkinson, G, Neidle, S. 登録日 2001-08-03 公開日 2002-06-28 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of the potassium form of an Oxytricha nova G-quadruplex. J.Mol.Biol., 320, 2002
1JRN	Orthorhombic form of Oxytricha telomeric DNA at 2.0A 分子名称: 5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)-3', POTASSIUM ION 著者 Haider, S.M, Parkinson, G, Neidle, S. 登録日 2001-08-14 公開日 2002-06-28 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of the potassium form of an Oxytricha nova G-quadruplex. J.Mol.Biol., 320, 2002
2I1T	Solution structure of Jingzhaotoxin-III, a novel toxin inhibiting both Nav and Kv channels 分子名称: Jingzhaotoxin-3 著者 Liao, Z, Peng, K, Liang, S. 登録日 2006-08-15 公開日 2006-08-29 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Solution structure of Jingzhaotoxin-III, a novel toxin inhibiting both Nav and Kv channels To be Published
7F3F	CryoEM structure of human Kv4.2-KChIP1 complex 分子名称: Isoform 2 of Kv channel-interacting protein 1, Potassium voltage-gated channel subfamily D member 2 著者 Kise, Y, Nureki, O. 登録日 2021-06-16 公開日 2021-10-13 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of gating modulation of Kv4 channel complexes. Nature, 599, 2021
6FEH	Solution Structure of CaM/Kv7.2-hAB Complex 分子名称: CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2,Potassium voltage-gated channel subfamily KQT member 2 著者 Bernardo-Seisdedos, G, Villarroel, A, Millet, O. 登録日 2018-01-02 公開日 2018-02-21 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural basis and energy landscape for the Ca2+gating and calmodulation of the Kv7.2 K+channel. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FEG	Solution Structure of CaM/Kv7.2-hAB Complex 分子名称: CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2,Potassium voltage-gated channel subfamily KQT member 2 著者 Bernardo-Seisdedos, G, Villarroel, A, Millet, O. 登録日 2018-01-02 公開日 2018-02-21 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural basis and energy landscape for the Ca2+gating and calmodulation of the Kv7.2 K+channel. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6N5W	Crystal structure of the Ca2+/CaM complex with independent peptides of Kv7.4 (KCNQ4) A & B domains 分子名称: CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 4 著者 Taylor, A.B, Archer, C.R, Shapiro, M.S. 登録日 2018-11-22 公開日 2019-03-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 A mutually induced conformational fit underlies Ca2+-directed interactions between calmodulin and the proximal C terminus of KCNQ4 K+channels. J. Biol. Chem., 294, 2019
7E83	CryoEM structure of the human Kv4.2-KChIP1 complex, intracellular region 分子名称: Kv channel-interacting protein 1, Potassium voltage-gated channel subfamily D member 2 著者 Kise, Y, Nureki, O. 登録日 2021-02-28 公開日 2021-10-13 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of gating modulation of Kv4 channel complexes. Nature, 599, 2021
7E84	CryoEM structure of human Kv4.2-KChIP1 complex 分子名称: Kv channel-interacting protein 1, Potassium voltage-gated channel subfamily D member 2 著者 Kise, Y, Nureki, O. 登録日 2021-02-28 公開日 2021-10-13 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of gating modulation of Kv4 channel complexes. Nature, 599, 2021
7E8E	CryoEM structure of human Kv4.2-DPP6S-KChIP1 complex, transmembrane and intracellular region 分子名称: Dipeptidyl aminopeptidase-like protein 6, Kv channel-interacting protein 1, Potassium voltage-gated channel subfamily D member 2 著者 Kise, Y, Nureki, O. 登録日 2021-03-01 公開日 2021-10-13 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis of gating modulation of Kv4 channel complexes. Nature, 599, 2021
7E8H	CryoEM structure of human Kv4.2-DPP6S-KChIP1 complex 分子名称: Dipeptidyl aminopeptidase-like protein 6, Kv channel-interacting protein 1, Potassium voltage-gated channel subfamily D member 2 著者 Kise, Y, Nureki, O. 登録日 2021-03-01 公開日 2021-10-13 最終更新日 2022-02-16 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structural basis of gating modulation of Kv4 channel complexes. Nature, 599, 2021

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