2N4I
| The solution structure of Skint-1, a critical determinant of dendritic epidermal gamma-delta T cell selection | 分子名称: | Selection and upkeep of intraepithelial T-cells protein 1 | 著者 | Salim, M, Knowles, T.J, Hart, R, Mohammed, F, Woodward, M.J, Willcox, C.R, Overduin, M, Hayday, A.C, Willcox, B.E. | 登録日 | 2015-06-18 | 公開日 | 2016-03-02 | 最終更新日 | 2024-10-09 | 実験手法 | SOLUTION NMR | 主引用文献 | Characterization of a Putative Receptor Binding Surface on Skint-1, a Critical Determinant of Dendritic Epidermal T Cell Selection. J.Biol.Chem., 291, 2016
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5C6W
| anti-CXCL13 scFv - E10 | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Tu, C, Bard, J, Mosyak, L. | 登録日 | 2015-06-23 | 公開日 | 2015-11-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Optimization of a scFv-based biotherapeutic by CDR side-chain clash repair To Be Published
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5C7K
| Crystal structure BG505 SOSIP gp140 HIV-1 Env trimer bound to broadly neutralizing antibodies PGT128 and 8ANC195 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab 8ANC195 heavy chain, ... | 著者 | Kong, L, Stanfield, R.L, Wilson, I.A. | 登録日 | 2015-06-24 | 公開日 | 2015-10-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (4.6019 Å) | 主引用文献 | Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer. Acta Crystallogr.,Sect.D, 71, 2015
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5C9K
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5CBA
| 3B4 in complex with CXCL13 - 3B4-CXCL13 | 分子名称: | 1,2-ETHANEDIOL, 3b4 heavy chain, 3b4 light chain, ... | 著者 | Tu, C, Bard, J, Mosyak, L. | 登録日 | 2015-06-30 | 公開日 | 2015-11-04 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A Combination of Structural and Empirical Analyses Delineates the Key Contacts Mediating Stability and Affinity Increases in an Optimized Biotherapeutic Single-chain Fv (scFv). J. Biol. Chem., 291, 2016
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5CBE
| E10 in complex with CXCL13 | 分子名称: | 1,2-ETHANEDIOL, C-X-C motif chemokine 13, E10 heavy chain, ... | 著者 | Tu, C, Bard, J, Mosyak, L. | 登録日 | 2015-06-30 | 公開日 | 2015-11-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A Combination of Structural and Empirical Analyses Delineates the Key Contacts Mediating Stability and Affinity Increases in an Optimized Biotherapeutic Single-chain Fv (scFv). J. Biol. Chem., 291, 2016
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5CUS
| Crystal Structure of sErbB3-Fab3379 Complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab LC region of KTN3379, IgG H chain, ... | 著者 | Lee, S, Schlessinger, J. | 登録日 | 2015-07-25 | 公開日 | 2015-10-14 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Inhibition of ErbB3 by a monoclonal antibody that locks the extracellular domain in an inactive configuration. Proc.Natl.Acad.Sci.USA, 112, 2015
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5D4K
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5ACL
| Mcg immunoglobulin variable domain with sulfasalazine | 分子名称: | 2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID, MCG, SULFATE ION | 著者 | Brumshtein, B, Esswein, S.R, Salwinski, L, Phillips, M.L, Ly, A.T, Cascio, D, Sawaya, M.R, Eisenberg, D.S. | 登録日 | 2015-08-17 | 公開日 | 2015-12-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Inhibition by small-molecule ligands of formation of amyloid fibrils of an immunoglobulin light chain variable domain. Elife, 4, 2015
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5ACM
| Mcg immunoglobulin variable domain with methylene blue | 分子名称: | 3,7-BIS(DIMETHYLAMINO)PHENOTHIAZIN-5-IUM, GLYCEROL, MCG, ... | 著者 | Brumshtein, B, Esswein, S.R, Salwinski, L, Phillips, M.L, Ly, A.T, Cascio, D, Sawaya, M.R, Eisenberg, D.S. | 登録日 | 2015-08-17 | 公開日 | 2015-12-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | 主引用文献 | Inhibition by small-molecule ligands of formation of amyloid fibrils of an immunoglobulin light chain variable domain. Elife, 4, 2015
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5D9Q
| Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with the Broadly Neutralizing Fab PGT122 and scFv NIH45-46 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | 著者 | Julien, J.-P, Stanfield, R.L, Ward, A.B, Wilson, I.A. | 登録日 | 2015-08-18 | 公開日 | 2016-08-17 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (4.4 Å) | 主引用文献 | Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design. Plos Pathog., 12, 2016
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5AYQ
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2N7B
| Solution structure of the human Siglec-8 lectin domain in complex with 6'sulfo sialyl Lewisx | 分子名称: | 3-aminopropan-1-ol, N-acetyl-alpha-neuraminic acid-(2-3)-6-O-sulfo-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, Sialic acid-binding Ig-like lectin 8 | 著者 | Proepster, J.M, Yang, F, Rabbani, S, Ernst, B, Allain, F.H.-T, Schubert, M. | 登録日 | 2015-09-07 | 公開日 | 2016-07-06 | 最終更新日 | 2020-07-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for sulfation-dependent self-glycan recognition by the human immune-inhibitory receptor Siglec-8. Proc.Natl.Acad.Sci.USA, 113, 2016
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2N7A
| Solution structure of the human Siglec-8 lectin domain | 分子名称: | Sialic acid-binding Ig-like lectin 8 | 著者 | Proepster, J.M, Yang, F, Rabbani, S, Ernst, B, Allain, F.H.-T, Schubert, M. | 登録日 | 2015-09-07 | 公開日 | 2016-07-06 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for sulfation-dependent self-glycan recognition by the human immune-inhibitory receptor Siglec-8. Proc.Natl.Acad.Sci.USA, 113, 2016
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5DZO
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5DZN
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5DZL
| Crystal structure of the protein human CEACAM1 | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 1 | 著者 | Huang, Y.H, Russell, A, Gandhi, A.K, Kondo, Y, Chen, Q, Petsko, G.A, Blumberg, R.S. | 登録日 | 2015-09-25 | 公開日 | 2015-10-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.4006 Å) | 主引用文献 | CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. Nature, 517, 2015
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5E56
| Crystal structure of mouse CTLA-4 | 分子名称: | Cytotoxic T-lymphocyte protein 4, SODIUM ION | 著者 | Fedorov, A.A, Fedorov, E.V, SAMANTA, D, Bonanno, J.B, Almo, S.C. | 登録日 | 2015-10-07 | 公開日 | 2015-10-28 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.504 Å) | 主引用文献 | Crystal structure of mouse CTLA-4 To Be Published
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5E5M
| Crystal structure of mouse CTLA-4 in complex with nanobody | 分子名称: | CTLA-4 nanobody, Cytotoxic T-lymphocyte protein 4, GLYCEROL | 著者 | Fedorov, A.A, Fedorov, E.V, Samanta, D, Bonanno, J.B, Almo, S.C. | 登録日 | 2015-10-08 | 公開日 | 2016-10-12 | 最終更新日 | 2019-01-30 | 実験手法 | X-RAY DIFFRACTION (2.182 Å) | 主引用文献 | Crystal structure of mouse CTLA-4 in complex with nanobody To Be Published
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5E6I
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5E9D
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5FKA
| Crystal structure of staphylococcal enterotoxin E in complex with a T cell receptor | 分子名称: | STAPHYLOCOCCAL ENTEROTOXIN E, T CELL RECEPTOR ALPHA CHAIN, T CELL RECEPTOR BETA CHAIN, ... | 著者 | Rodstrom, K.E.J, Regenthal, P, Lindkvist-Petersson, K. | 登録日 | 2015-10-15 | 公開日 | 2016-05-25 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Two Common Structural Motifs for Tcr Recognition by Staphylococcal Enterotoxins. Sci.Rep., 6, 2016
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5FK9
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5EB9
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5EBG
| Crystal structure of bovine CD8aa homodimer | 分子名称: | T-cell surface glycoprotein CD8 alpha chain | 著者 | Liu, Y, Li, X, Zhang, N, Qi, J, Xia, C. | 登録日 | 2015-10-19 | 公開日 | 2016-09-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The structural basis of chicken, swine and bovine CD8 alpha alpha dimers provides insight into the co-evolution with MHC I in endotherm species. Sci Rep, 6, 2016
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