8PCQ
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![BU of 8pcq by Molmil](/molmil-images/mine/8pcq) | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 500 ms | 分子名称: | BORATE ION, Beta-lactamase, SULFATE ION, ... | 著者 | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | 登録日 | 2023-06-11 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
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8PCU
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![BU of 8pcu by Molmil](/molmil-images/mine/8pcu) | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 5000 ms | 分子名称: | BORATE ION, Beta-lactamase, SULFATE ION, ... | 著者 | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | 登録日 | 2023-06-11 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
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8PC9
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![BU of 8pc9 by Molmil](/molmil-images/mine/8pc9) | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 0 ms - native. | 分子名称: | Beta-lactamase, SULFATE ION | 著者 | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | 登録日 | 2023-06-11 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
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8PCT
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![BU of 8pct by Molmil](/molmil-images/mine/8pct) | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 2500 ms | 分子名称: | BORATE ION, Beta-lactamase, SULFATE ION, ... | 著者 | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | 登録日 | 2023-06-11 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
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8PCM
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![BU of 8pcm by Molmil](/molmil-images/mine/8pcm) | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 80 ms | 分子名称: | BORATE ION, Beta-lactamase, SULFATE ION, ... | 著者 | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | 登録日 | 2023-06-11 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
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8PCI
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![BU of 8pci by Molmil](/molmil-images/mine/8pci) | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 5000 ms | 分子名称: | BORATE ION, Beta-lactamase, SULFATE ION | 著者 | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | 登録日 | 2023-06-11 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
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8PCB
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![BU of 8pcb by Molmil](/molmil-images/mine/8pcb) | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 80 ms | 分子名称: | BORATE ION, Beta-lactamase, SULFATE ION | 著者 | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | 登録日 | 2023-06-11 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
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8PCN
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![BU of 8pcn by Molmil](/molmil-images/mine/8pcn) | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 100 ms | 分子名称: | BORATE ION, Beta-lactamase, SULFATE ION, ... | 著者 | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | 登録日 | 2023-06-11 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
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8PCP
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![BU of 8pcp by Molmil](/molmil-images/mine/8pcp) | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 250 ms | 分子名称: | BORATE ION, Beta-lactamase, SULFATE ION, ... | 著者 | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | 登録日 | 2023-06-11 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
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8PCG
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![BU of 8pcg by Molmil](/molmil-images/mine/8pcg) | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 2000 ms | 分子名称: | BORATE ION, Beta-lactamase, SULFATE ION | 著者 | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | 登録日 | 2023-06-11 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
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8PCV
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![BU of 8pcv by Molmil](/molmil-images/mine/8pcv) | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 10000 ms | 分子名称: | BORATE ION, Beta-lactamase, SULFATE ION, ... | 著者 | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | 登録日 | 2023-06-11 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
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8PCS
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![BU of 8pcs by Molmil](/molmil-images/mine/8pcs) | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 1250 ms | 分子名称: | BORATE ION, Beta-lactamase, SULFATE ION, ... | 著者 | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | 登録日 | 2023-06-11 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
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8PCO
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![BU of 8pco by Molmil](/molmil-images/mine/8pco) | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 150 ms | 分子名称: | BORATE ION, Beta-lactamase, SULFATE ION, ... | 著者 | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | 登録日 | 2023-06-11 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
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6I5G
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![BU of 6i5g by Molmil](/molmil-images/mine/6i5g) | X-ray structure of human soluble Epoxide Hydrolase C-terminal Domain (hsEH CTD)in complex with 15d-PGJ2 | 分子名称: | (5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid, 1,2-ETHANEDIOL, Bifunctional epoxide hydrolase 2 | 著者 | Abis, G, Kopec, J, Yue, W.W, Conte, M.R. | 登録日 | 2018-11-13 | 公開日 | 2019-05-29 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | 15-deoxy-Delta12,14-Prostaglandin J2inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism. Commun Biol, 2, 2019
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6IFH
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![BU of 6ifh by Molmil](/molmil-images/mine/6ifh) | Unphosphorylated Spo0F from Paenisporosarcina sp. TG-14 | 分子名称: | MAGNESIUM ION, Sporulation initiation phosphotransferase F | 著者 | Lee, J.H, Lee, C.W. | 登録日 | 2018-09-20 | 公開日 | 2019-01-16 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of unphosphorylated Spo0F from Paenisporosarcina sp. TG-14, a psychrophilic bacterium isolated from an Antarctic glacier Biodesign, 6(4), 2019
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6H0M
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![BU of 6h0m by Molmil](/molmil-images/mine/6h0m) | 17beta-hydroxysteroid dehydrogenase type 14 mutant K158A in complex with Nicotinamide Adenine Dinucleotide | 分子名称: | 17-beta-hydroxysteroid dehydrogenase 14, DIMETHYL SULFOXIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Badran, M, Klebe, G, Heine, A, Marchais-Oberwinkler, S. | 登録日 | 2018-07-10 | 公開日 | 2019-07-31 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | 17beta-hydroxysteroid dehydrogenase type 14 mutant K158A in complex with Nicotinamide Adenine Dinucleotide To Be Published
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1A6T
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![BU of 1a6t by Molmil](/molmil-images/mine/1a6t) | |
3ZG3
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![BU of 3zg3 by Molmil](/molmil-images/mine/3zg3) | STEROL 14-ALPHA DEMETHYLASE (CYP51)FROM TRYPANOSOMA CRUZI IN COMPLEX WITH THE PYRIDINE INHIBITOR N-(1-(5-(trifluoromethyl)(pyridin-2-yl)) piperidin-4yl)-N-(4-(trifluoromethyl)phenyl)pyridin-3-amine (EPL- BS967, UDD) | 分子名称: | N-[4-(trifluoromethyl)phenyl]-N-[1-[5-(trifluoromethyl)pyridin-2-yl]piperidin-4-yl]pyridin-3-amine, PROTOPORPHYRIN IX CONTAINING FE, STEROL 14-ALPHA DEMETHYLASE | 著者 | Hargrove, T.Y, Wawrzak, Z, Keenan, M, Chatelain, E, Lepesheva, G.I. | 登録日 | 2012-12-14 | 公開日 | 2013-09-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Complexes of Trypanosoma Cruzi Sterol 14Alpha-Demethylase (Cyp51) with Two Pyridine-Based Drug Candidates for Chagas Disease: Structural Basis for Pathogen-Selectivity J.Biol.Chem., 288, 2013
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3ZG2
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![BU of 3zg2 by Molmil](/molmil-images/mine/3zg2) | Sterol 14 alpha-demethylase (CYP51) from Trypanosoma cruzi in complex with the pyridine inhibitor (S)-2-(4-chlorophenyl)-2-(pyridin-3-yl)-1- (4-(4-(trifluoromethyl)phenyl)piperazin-1-yl)ethanone (EPL-BS1246,UDO) | 分子名称: | (S)-2-(4-chlorophenyl)-2-pyridin-3-yl-1-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]ethanone, PROTOPORPHYRIN IX CONTAINING FE, STEROL 14-ALPHA DEMETHYLASE | 著者 | Hargrove, T.Y, Wawrzak, Z, Keenan, M, Chatelain, E, Lepesheva, G.I. | 登録日 | 2012-12-14 | 公開日 | 2013-09-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Complexes of Trypanosoma Cruzi Sterol 14Alpha-Demethylase (Cyp51) with Two Pyridine-Based Drug Candidates for Chagas Disease: Structural Basis for Pathogen-Selectivity J.Biol.Chem., 288, 2013
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7RY9
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![BU of 7ry9 by Molmil](/molmil-images/mine/7ry9) | S. CEREVISIAE CYP51 I471T mutant COMPLEXED WITH Voriconazole | 分子名称: | Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE, TETRAETHYLENE GLYCOL, ... | 著者 | Graham, D.O, Wilson, R.K, Ruma, Y.N, Keniya, M.V, Tyndall, J.D, Monk, B.C. | 登録日 | 2021-08-24 | 公開日 | 2021-09-01 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural Insights into the Azole Resistance of the Candida albicans Darlington Strain Using Saccharomyces cerevisiae Lanosterol 14 alpha-Demethylase as a Surrogate. J Fungi (Basel), 7, 2021
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6UNB
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![BU of 6unb by Molmil](/molmil-images/mine/6unb) | Crystal structure of CTX-M-14 in complex with temocillin | 分子名称: | (2R,4S)-2-[(1S)-1-{[(2R)-2-carboxy-2-(thiophen-3-yl)acetyl]amino}-1-methoxy-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4 -carboxylic acid, Beta-lactamase, PHOSPHATE ION | 著者 | Sacco, M, Chen, Y. | 登録日 | 2019-10-11 | 公開日 | 2019-10-30 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Influence of the alpha-Methoxy Group on the Reaction of Temocillin with Pseudomonas aeruginosa PBP3 and CTX-M-14 beta-Lactamase. Antimicrob.Agents Chemother., 64, 2019
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4ZE1
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![BU of 4ze1 by Molmil](/molmil-images/mine/4ze1) | Saccharomyces cerevisiae CYP51 Y140F mutant complexed with posaconazole in the active site | 分子名称: | Lanosterol 14-alpha demethylase, POSACONAZOLE, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Sagatova, A, Keniya, M.V, Wilson, R, Tyndall, J.D.A, Monk, B.C. | 登録日 | 2015-04-20 | 公開日 | 2016-03-30 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14 alpha-demethylase. Sci Rep, 6, 2016
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1P6O
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![BU of 1p6o by Molmil](/molmil-images/mine/1p6o) | The crystal structure of yeast cytosine deaminase bound to 4(R)-hydroxyl-3,4-dihydropyrimidine at 1.14 angstroms. | 分子名称: | 4-HYDROXY-3,4-DIHYDRO-1H-PYRIMIDIN-2-ONE, ACETIC ACID, CALCIUM ION, ... | 著者 | Ireton, G.C, Black, M.E, Stoddard, B.L. | 登録日 | 2003-04-29 | 公開日 | 2003-08-19 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | 主引用文献 | The 1.14 a crystal structure of yeast Cytosine deaminase. Evolution of nucleotide salvage enzymes and implications for genetic chemotherapy. Structure, 11, 2003
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8PCA
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![BU of 8pca by Molmil](/molmil-images/mine/8pca) | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 50 ms | 分子名称: | Beta-lactamase, SULFATE ION | 著者 | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | 登録日 | 2023-06-11 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
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8PCC
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![BU of 8pcc by Molmil](/molmil-images/mine/8pcc) | Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 100 ms | 分子名称: | BORATE ION, Beta-lactamase, SULFATE ION | 著者 | Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. | 登録日 | 2023-06-11 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
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