PDB: 36667 件ウェブページステータス検索Chemie searchBIRD

---

5RP5	PanDDA analysis group deposition -- Proteinase K crystal structure Apo48 分子名称: Proteinase K, SULFATE ION 著者 Lima, G.M.A, Talibov, V, Benz, L.S, Jagudin, E, Mueller, U. 登録日 2020-09-23 公開日 2021-05-26 最終更新日 2021-06-23 実験手法 X-RAY DIFFRACTION (1.09 Å) 主引用文献 FragMAXapp: crystallographic fragment-screening data-analysis and project-management system. Acta Crystallogr D Struct Biol, 77, 2021
5RPA	PanDDA analysis group deposition -- Proteinase K changed state model for fragment Frag Xtal Screen E3a 分子名称: 3-[(4E)-4-imino-5,6-dimethylfuro[2,3-d]pyrimidin-3(4H)-yl]-N,N-dimethylpropan-1-amine, Proteinase K, SULFATE ION 著者 Lima, G.M.A, Talibov, V, Benz, L.S, Jagudin, E, Mueller, U. 登録日 2020-09-23 公開日 2021-05-26 最終更新日 2021-06-23 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 FragMAXapp: crystallographic fragment-screening data-analysis and project-management system. Acta Crystallogr D Struct Biol, 77, 2021
5RPG	PanDDA analysis group deposition -- Proteinase K changed state model for fragment Frag Xtal Screen H2a 分子名称: Proteinase K, SULFATE ION, TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACID 著者 Lima, G.M.A, Talibov, V, Benz, L.S, Jagudin, E, Mueller, U. 登録日 2020-09-23 公開日 2021-05-26 最終更新日 2021-06-23 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 FragMAXapp: crystallographic fragment-screening data-analysis and project-management system. Acta Crystallogr D Struct Biol, 77, 2021
5RPJ	PanDDA analysis group deposition -- Proteinase K changed state model for fragment Frag Xtal Screen B12a 分子名称: 4-oxo-N-[(1S)-1-(pyridin-3-yl)ethyl]-4-(thiophen-2-yl)butanamide, Proteinase K, SULFATE ION 著者 Lima, G.M.A, Talibov, V, Benz, L.S, Jagudin, E, Mueller, U. 登録日 2020-09-23 公開日 2021-05-26 最終更新日 2021-06-23 実験手法 X-RAY DIFFRACTION (1.27 Å) 主引用文献 FragMAXapp: crystallographic fragment-screening data-analysis and project-management system. Acta Crystallogr D Struct Biol, 77, 2021
5RON	PanDDA analysis group deposition -- Proteinase K changed state model for fragment Frag Xtal Screen E4a 分子名称: 2-(1H-imidazol-1-yl)-N-(trans-4-methylcyclohexyl)acetamide, Proteinase K, SULFATE ION 著者 Lima, G.M.A, Talibov, V, Benz, L.S, Jagudin, E, Mueller, U. 登録日 2020-09-23 公開日 2021-05-26 最終更新日 2021-06-23 実験手法 X-RAY DIFFRACTION (1.22 Å) 主引用文献 FragMAXapp: crystallographic fragment-screening data-analysis and project-management system. Acta Crystallogr D Struct Biol, 77, 2021
5ROM	PanDDA analysis group deposition -- Proteinase K crystal structure Apo45 分子名称: Proteinase K, SULFATE ION 著者 Lima, G.M.A, Talibov, V, Benz, L.S, Jagudin, E, Mueller, U. 登録日 2020-09-23 公開日 2021-05-26 最終更新日 2021-06-23 実験手法 X-RAY DIFFRACTION (1.07 Å) 主引用文献 FragMAXapp: crystallographic fragment-screening data-analysis and project-management system. Acta Crystallogr D Struct Biol, 77, 2021
5ROZ	PanDDA analysis group deposition -- Proteinase K crystal structure Apo41 分子名称: Proteinase K, SULFATE ION 著者 Lima, G.M.A, Talibov, V, Benz, L.S, Jagudin, E, Mueller, U. 登録日 2020-09-23 公開日 2021-05-26 最終更新日 2021-06-23 実験手法 X-RAY DIFFRACTION (1.14 Å) 主引用文献 FragMAXapp: crystallographic fragment-screening data-analysis and project-management system. Acta Crystallogr D Struct Biol, 77, 2021
5RPU	PanDDA analysis group deposition -- Proteinase K crystal structure Apo67 分子名称: Proteinase K, SULFATE ION 著者 Lima, G.M.A, Talibov, V, Benz, L.S, Jagudin, E, Mueller, U. 登録日 2020-09-23 公開日 2021-05-26 最終更新日 2021-06-23 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 FragMAXapp: crystallographic fragment-screening data-analysis and project-management system. Acta Crystallogr D Struct Biol, 77, 2021
7AGG	HAd7 knob in complex with 2 EC2-EC3 modules of DSG-2 分子名称: Desmoglein-2, Fiber 著者 Effantin, G, Vassal-Stermann, E, Fender, P. 登録日 2020-09-22 公開日 2020-10-14 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Binding Mechanism Elucidation of the Acute Respiratory Disease Causing Agent Adenovirus of Serotype 7 to Desmoglein-2. Viruses, 12, 2020
7AGF	HAd7 knob in complex with 3 EC2-EC3 modules of DSG-2 分子名称: Desmoglein-2, Fiber 著者 Effantin, G, Vassal-Stermann, E, Fender, P. 登録日 2020-09-22 公開日 2020-10-14 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Binding Mechanism Elucidation of the Acute Respiratory Disease Causing Agent Adenovirus of Serotype 7 to Desmoglein-2. Viruses, 12, 2020
7K7J	EphB6 receptor ectodomain 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-B receptor 6 著者 Goldgur, Y, Himanen, J. 登録日 2020-09-22 公開日 2021-04-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.004 Å) 主引用文献 Structure of the EphB6 receptor ectodomain. Plos One, 16, 2021
7AGB	Protease Sapp1p from Candida parapsilosis in complex with KB70 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, Candidapepsin, ... 著者 Dostal, J, Heidingsfeld, O, Brynda, J. 登録日 2020-09-22 公開日 2021-04-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural determinants for subnanomolar inhibition of the secreted aspartic protease Sapp1p from Candida parapsilosis . J Enzyme Inhib Med Chem, 36, 2021
7AGE	Protease Sapp1p from Candida parapsilosis in complex with KB32 分子名称: Candidapepsin, DI(HYDROXYETHYL)ETHER, Pepstatin 著者 Dostal, J, Heidingsfeld, O, Brynda, J. 登録日 2020-09-22 公開日 2021-04-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structural determinants for subnanomolar inhibition of the secreted aspartic protease Sapp1p from Candida parapsilosis . J Enzyme Inhib Med Chem, 36, 2021
7AGD	Protease Sapp1p from Candida parapsilosis in complex with KB75 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Candidapepsin, DI(HYDROXYETHYL)ETHER, ... 著者 Dostal, J, Heidingsfeld, O, Brynda, J. 登録日 2020-09-22 公開日 2021-04-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural determinants for subnanomolar inhibition of the secreted aspartic protease Sapp1p from Candida parapsilosis . J Enzyme Inhib Med Chem, 36, 2021
7AGC	Protease Sapp1p from Candida parapsilosis in complex with KB74 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Candidapepsin, DI(HYDROXYETHYL)ETHER, ... 著者 Dostal, J, Heidingsfeld, O, Brynda, J. 登録日 2020-09-22 公開日 2021-04-21 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structural determinants for subnanomolar inhibition of the secreted aspartic protease Sapp1p from Candida parapsilosis . J Enzyme Inhib Med Chem, 36, 2021
7D43	eIF2B-eIF2(aP), aPg complex 分子名称: Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit 3, ... 著者 Kashiwagi, K, Ito, T. 登録日 2020-09-22 公開日 2020-12-09 最終更新日 2021-01-27 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B. Mol.Cell, 81, 2021
7AG0	Complex between the bone morphogenetic protein 2 and its antagonist Noggin 分子名称: Bone morphogenetic protein 2, GLYCEROL, Noggin 著者 Robert, C, Bruck, F, Herman, R, Vandevenne, M, Filee, P, Kerff, F, Matagne, A. 登録日 2020-09-21 公開日 2022-04-13 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.104 Å) 主引用文献 Structural analysis of the interaction between human cytokine BMP-2 and the antagonist Noggin reveals molecular details of cell chondrogenesis inhibition. J.Biol.Chem., 299, 2023
7D3R	FOOT AND MOUTH DISEASE VIRUS A/WH/CHA/09-BOUND THE SINGLE CHAIN FRAGME ANTIBODY R50 分子名称: A/WH/CHA/09 VP1, A/WH/CHA/09 VP2, A/WH/CHA/09 VP3, ... 著者 He, Y, Lou, Z. 登録日 2020-09-20 公開日 2021-04-14 最終更新日 2021-05-12 実験手法 ELECTRON MICROSCOPY (3.49 Å) 主引用文献 Structures of Foot-and-mouth Disease Virus with neutralizing antibodies derived from recovered natural host reveal a mechanism for cross-serotype neutralization. Plos Pathog., 17, 2021
7D3S	Human SECR in complex with an engineered Gs heterotrimer 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Fukuhara, S, Kobayashi, K, Kusakizako, T, Shihoya, W, Nureki, O. 登録日 2020-09-20 公開日 2020-11-04 最終更新日 2020-12-30 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structure of the human secretin receptor coupled to an engineered heterotrimeric G protein. Biochem.Biophys.Res.Commun., 533, 2020
7D3E	Cryo-EM structure of human DUOX1-DUOXA1 in low-calcium state 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Dual oxidase 1, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Chen, L, Wu, J.X. 登録日 2020-09-19 公開日 2020-12-09 最終更新日 2021-06-23 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structures of human dual oxidase 1 complex in low-calcium and high-calcium states. Nat Commun, 12, 2021
7D3M	FOOT AND MOUTH DISEASE VIRUS O/TIBET/99-BOUND THE SINGLE CHAIN FRAGMEN ANTIBODY R50 分子名称: O/TIBET/99 VP1, O/TIBET/99 VP2, O/TIBET/99 VP3, ... 著者 He, Y, Lou, Z. 登録日 2020-09-19 公開日 2021-04-14 最終更新日 2021-05-12 実験手法 ELECTRON MICROSCOPY (3.94 Å) 主引用文献 Structures of Foot-and-mouth Disease Virus with neutralizing antibodies derived from recovered natural host reveal a mechanism for cross-serotype neutralization. Plos Pathog., 17, 2021
7D3K	FOOT AND MOUTH DISEASE VIRUS O/TIBET/99-BOUND THE SINGLE CHAIN FRAGMEN ANTIBODY B77 分子名称: B77 VH, B77 VL, O/TIBET/99 VP1, ... 著者 He, Y, Lou, Z. 登録日 2020-09-19 公開日 2021-04-14 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structures of Foot-and-mouth Disease Virus with neutralizing antibodies derived from recovered natural host reveal a mechanism for cross-serotype neutralization. Plos Pathog., 17, 2021
7D3L	FOOT AND MOUTH DISEASE VIRUS O/TIBET/99-BOUND THE SINGLE CHAIN FRAGMEN ANTIBODY F145 分子名称: F145 VH, F145 VL, O/TIBET/99 VP1, ... 著者 He, Y, Lou, Z. 登録日 2020-09-19 公開日 2021-04-14 最終更新日 2021-05-12 実験手法 ELECTRON MICROSCOPY (3.68 Å) 主引用文献 Structures of Foot-and-mouth Disease Virus with neutralizing antibodies derived from recovered natural host reveal a mechanism for cross-serotype neutralization. Plos Pathog., 17, 2021
7D3F	Cryo-EM structure of human DUOX1-DUOXA1 in high-calcium state 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Dual oxidase 1, ... 著者 Chen, L, Wu, J.X. 登録日 2020-09-19 公開日 2020-12-09 最終更新日 2021-06-23 実験手法 ELECTRON MICROSCOPY (2.3 Å) 主引用文献 Structures of human dual oxidase 1 complex in low-calcium and high-calcium states. Nat Commun, 12, 2021
7D36	Crystal Structure of BACE1 in complex with N-{3-[(3S)-1-amino-5-fluoro-3-methyl-3,4-dihydro-2,6-naphthyridin-3-yl]-4-fluorophenyl}-5-cyano-3-methylpyridine-2-carboxamide 分子名称: Beta-secretase 1, GLYCEROL, IODIDE ION, ... 著者 Nakahara, K, Mitsuoka, Y, Kasuya, S, Yamamoto, T, Yamamoto, S, Ito, H, Kido, Y, Kusakabe, K.I. 登録日 2020-09-18 公開日 2021-07-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Balancing potency and basicity by incorporating fluoropyridine moieties: Discovery of a 1-amino-3,4-dihydro-2,6-naphthyridine BACE1 inhibitor that affords robust and sustained central A beta reduction. Eur.J.Med.Chem., 216, 2021

<312313314315316317318319320321322323324325326327>